Comparing Bupropion vs Sibutramine
| Bupropion | Sibutramine |
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| Bupropion | Sibutramine |
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Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight). Sibutramine may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
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| More about Bupropion | |||||||||
| Ratings & Reviews | |||||||||
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Bupropion has an average rating of 7.0 out of 10 from a total of 2900 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sibutramine has an average rating of 8.5 out of 10 from a total of 93 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 5% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Bupropion side effects |
View all Sibutramine side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Bupropion prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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30 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 527 drugs are known to interact with Bupropion:
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A total of 587 drugs are known to interact with Sibutramine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 30, 1985 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
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N/A |
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| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.