Benztropine Alternatives Compared
| Benztropine | Trihexyphenidyl | Diphenhydramine |
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| Benztropine | Trihexyphenidyl | Diphenhydramine |
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Prescription only
Benztropine may be used to treat symptoms of Parkinson's disease or alleviate side effects that affect movement caused by antipsychotics. However, it may cause unwanted effects such as blurred... View more |
Prescription only
Prescribed for Extrapyramidal Reaction, Cerebral Spasticity, Parkinson's Disease. Trihexyphenidyl may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Diphenhydramine is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side... View more |
Related suggestions Extrapyramidal Reaction
Popular comparisons
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| More about Benztropine | More about Trihexyphenidyl | More about Diphenhydramine | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Benztropine has an average rating of 6.6 out of 10 from a total of 36 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 32% reported a negative effect. |
Trihexyphenidyl has an average rating of 6.6 out of 10 from a total of 24 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 27% reported a negative effect. |
Diphenhydramine has an average rating of 5.5 out of 10 from a total of 532 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 41% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Benztropine prices |
View all Trihexyphenidyl prices |
View all Diphenhydramine prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Trihexy | Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Aurodryl Children's Allergy, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Histaprin, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nytol, Nytol Caplet, Nytol QuickCaps, Pharbedryl, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep Tab II, Sleep-ettes D, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Trux-adryl, Twilite, Unisom Liquid, Unisom SleepGels, Unisom SleepMelts, Unisom SleepMinis, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief, Z-Sleep, ZzzQuil View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
4.1 hours |
9.3 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 345 drugs are known to interact with Benztropine:
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A total of 336 drugs are known to interact with Trihexyphenidyl:
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A total of 450 drugs are known to interact with Diphenhydramine:
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| First Approval Date | ||||||||||||||||||||||||||
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March 05, 1954 |
May 13, 1949 |
March 04, 1946 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.