Comparing Baclofen vs Zanaflex
| Baclofen | Zanaflex (tizanidine) |
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| Baclofen | Zanaflex (tizanidine) |
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|---|---|---|
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Prescription only
Baclofen relieves muscle spasms associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Prescription only
Prescribed for Muscle Spasm, Spasticity. Zanaflex may also be used for purposes not listed in this medication guide. |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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| More about Baclofen | More about Zanaflex (tizanidine) | |
| Ratings & Reviews | ||
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Baclofen has an average rating of 7.0 out of 10 from a total of 447 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Zanaflex has an average rating of 7.6 out of 10 from a total of 116 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 12% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all Baclofen side effects |
View all Zanaflex side effects |
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| Drug Class | ||
| Generic Availability | ||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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| Brand Names | ||
| Fleqsuvy, Gablofen, Lioresal, Lioresal Intrathecal, Lyvispah, Ozobax, Ozobax DS | Other tizanidine brands include: Ontralfy | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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6.8 hours |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 369 drugs are known to interact with Baclofen:
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A total of 638 drugs are known to interact with Zanaflex:
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| Alcohol/Food/Lifestyle Interactions | ||
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| Disease Interactions | ||
| First Approval Date | ||
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November 22, 1977 |
November 27, 1996 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.