Comparing Alka-Seltzer Original vs Pepto-Bismol
| Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | Pepto-Bismol (bismuth subsalicylate) |
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| Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | Pepto-Bismol (bismuth subsalicylate) |
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Over-the-counter
Prescribed for Gas, Indigestion, Headache. Alka-Seltzer Original may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Helicobacter Pylori Infection, Diarrhea - Chronic, Indigestion, Traveler's Diarrhea, Diarrhea - Acute, Diarrhea, Lymphocytic Colitis. Pepto-Bismol may also be used for purposes not... View more |
Related suggestions Indigestion
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| More about Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) | More about Pepto-Bismol (bismuth subsalicylate) | |
| Ratings & Reviews | ||
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Alka-Seltzer Original has an average rating of 8.5 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect. |
Pepto-Bismol has an average rating of 7.5 out of 10 from a total of 33 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
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View all Alka-Seltzer Original side effects |
View all Pepto-Bismol side effects |
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| Drug Class | ||
| Generic Availability | ||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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| Brand Names | ||
| Other aspirin/citric acid/sodium bicarbonate brands include: Alka-Seltzer Extra Strength, Alka-Seltzer Lemon-Lime, Bromo Seltzer, Effervescent Pain Relief, Medique Medi-Seltzer, Picot Plus, Vida Mia Pain Relief, Winco Foods Effervescent Antacid and Pain Relief, Zee-Seltzer Antacid and Pain Reliever View more | Other bismuth subsalicylate brands include: Bismarex, Bismatrol, Bismatrol Maximum Strength, Childrens Kaopectate, Kaopectate, Kola-Pectin DS, Maalox Total Relief, Peptic Relief, Pepto-Bismol InstaCool, Pepto-Bismol Original Strength, Percy Medicine, Pink Bismuth, Soothe Caplets, Stomach Relief View more | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
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10 hours |
33 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category N
Not classified
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Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 468 drugs are known to interact with Alka-Seltzer Original:
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A total of 135 drugs are known to interact with Pepto-Bismol:
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
| First Approval Date | ||
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N/A |
N/A |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
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N/A |
N/A |
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| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.