Comparing Adapalene Topical vs Differin
| Adapalene topical | Differin (adapalene) |
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| Adapalene topical | Differin (adapalene) |
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Prescription and OTC
Prescribed for Acne. Adapalene topical may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Acne. Differin may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Adapalene topical | More about Differin (adapalene) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Adapalene topical has an average rating of 6.3 out of 10 from a total of 516 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 32% reported a negative effect. |
Differin has an average rating of 6.1 out of 10 from a total of 344 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 36% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Adapalene topical side effects |
View all Differin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Adapalene topical prices |
View all Differin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Differin, Plixda | Other adapalene brands include: Plixda | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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51 hours |
51 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 12 drugs are known to interact with Adapalene topical:
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A total of 12 drugs are known to interact with Differin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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May 31, 1996 |
May 31, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.