Skip to main content

Venlafaxine for Hot Flashes User Reviews (Page 3)

Brand names: Effexor, Effexor XR

Venlafaxine has an average rating of 6.7 out of 10 from a total of 130 reviews for the off-label treatment of Hot Flashes. 56% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Venlafaxine

  • ginge...
  • March 11, 2016

"I have been taking Effexor for hot flashes for 4 years now. While it did relieve the flashes I must tell you about a devastating experience I had this week. The Effexor caused me to have a false positive reading for PCP on a pre employment drug screen. I will NEVER take this medication again and am on a mission to let everyone know about this problem."

1 / 10
Was this helpful?YesNo
52 Report
  • thedeb
  • January 11, 2009

Effexor XR (venlafaxine) "I have been taking Effexor XR for approximately 6 months now. My hot flashes were very severe. I would be soaked and wet from top of my head down to my legs. Cold glass of water hardly touched it. After taking Effexor I only have little sweating around my head and neck maybe two to five times a month. It is a great relief."

9 / 10
Was this helpful?YesNo
82 Report
  • Pimfa
  • Taken for 2 to 5 years
  • December 23, 2015

"I started suffering very badly from hot flashes about 2 years ago. When I would work out and do cardio, I would literally leave puddles. It was scary because I didn't know what was going on at the time. Someone I met recommended I try it. I was suffering so bad, I didn't want to be on antidepressants, but I was desperate. I didn't have to wait long, I went from having about six hot flashes a day, lasting about two to three minutes, to having three or four mini flashes. I was incredibly grateful, was able to sleep through the night as well. Just recently, they started to become unbearable again, so they increased the dosage. Really does work. Currently on 150 milligrams. I may have one or two flashes during the day and and maybe two at night"

10 / 10
Was this helpful?YesNo
52 Report

Frequently asked questions

  • Anonymous
  • November 22, 2011

Effexor XR (venlafaxine) "I had horrible hot flashes getting one every 45 minutes to an hour on average. Since I've been on Effexor XR 37.5 my hot flashes have decreased to on average one a day and it's much less severe. I been taking it for over a year. Only draw back for me is a reduced sex drive."

Was this helpful?YesNo
69 Report
  • Sue
  • Taken for 2 to 5 years
  • February 21, 2020

"I was given this med Effexor by my oncologist for hot flashes. I've been on it 4 yrs. If I forgot one dose, the withdrawal it horrific! Brain zaps, dizzy, disoriented, nauseated, shaking, flu like aches from missing one dose is crazy. I've been tapering from 150 mg to 75mg and it's taken 2 yrs. Your brain has to heal. For me it takes a nightmare of two months to level out. Please weigh the pros and cons. It has ruined my life. I'm a total introvert and used to be a social person."

1 / 10
Was this helpful?YesNo
31 Report

Are you taking this medicine?

  • Tinkers
  • Taken for less than 1 month
  • October 22, 2016

"My doctor put me on this medicine for hot flashes and the roller coaster emotions that come along with pre-menopause. 37.5mg. After I took the first dose I started sweating, shaking, got nauseous and started violently vomiting, along with diarrhea. I had the dry heaves for 4 hours. Very scary. I almost went to the ER. I will not be taking this medicine! I'd rather have the hot flashes!!"

1 / 10
Was this helpful?YesNo
46 Report
  • marri...
  • September 4, 2011

Effexor XR (venlafaxine) "I have suffered with hot flashes since my late teens and began menopause at 50. I tried Effexor XR just to see if it would help and was so surprised with the RELIEF that I got from it. It helped so much. It didn't stop them. I don't think anything can, but it sure did cut the number of hot flashes by at least half. When I do have one, it's a butt-kicker, but by cutting the number in half, my quality of life has been improved so much. Between the Effexor XR and Topamax putting a complete halt to my migraines, life is really good again!"

10 / 10
Was this helpful?YesNo
66 Report
  • Bunky
  • June 1, 2015

"I had a hysterectomy over a year ago, and immediately started with hot flashes. The flashes were so bad I was experiencing 5-6 severe hot flashes an hour, immediately after starting venlafaxine 37.5 for 1 week/then 75mg after, they decreased in severity and I may have 4-5 a day, and for the first time in over a year I am able to sleep most nights all the way through. By taking venlafaxine, I was able to discontinue 2 medications (6 pills)."

9 / 10
Was this helpful?YesNo
49 Report
  • chroke
  • February 12, 2016

"My doctor prescribed venlafaxine for my hot flashes. When I talked to her about going on hormone therapy she suggested that venlafaxine may be a good option and not understanding much about anti-depressants it sounded like a good idea.. wow was i wrong! I took this medication for a total of approx. 2 months. At first 37 mg worked great but then my body adjusted within a few days and the hot flashes returned I ended up increasing to a total of 3 37mg per day tablets but continued to have hot flashes and my sex drive became non-existent. I finally realized what I was doing to my body when I ran out for almost 5 days and the withdrawal symptoms made me feel like a zombie (seriously). This stuff is a very strong drug and very addictive."

1 / 10
Was this helpful?YesNo
46 Report
  • Chenise
  • Taken for 2 to 5 years
  • December 6, 2019

"I was prescribed this for hot flashes. My doctor didn't tell me 1) Don't take this later in the day, it can impair your ability to fall asleep. For months after starting it, it took 2-3 hours to fall asleep nightly. I did some web research on my own and learned to take it no later than early afternoon. When I told my doctor she said "I'm sorry I forgot to tell you about that". While traveling, I ran out and didn't take the medicine for two days. I got home from my trip, felt very depressed; I was crying for no reason. My friends picked up my refill (I felt so bad I didn't even want to leave the house) and I felt better once I resumed taking it. Once again, my doctor failed to provide critical information. I am weaning myself off of it and am now at the point where what used to be one day's dose is now split into 5 days doses, I step down to a lesser amount in a gel capsule every 10 days. I will probably be done within a month. No withdrawal side effects at all now."

2 / 10
Was this helpful?YesNo
29 Report
  • Redkat
  • December 21, 2011

"I had run out of Venlafaxine 75mg ER, For 2 days and my side effects were horrible. I felt like I was walking on my nerves, every move was like zap. My emotions were crazy and my hot flashes horrendous. I just wonder what its doing to my insides if I have that bad of side effects."

Was this helpful?YesNo
58 Report
  • moes...
  • February 11, 2018

"A new primary care physician suggested Effexor to treat my hot flashes. I was so sleep deprived and miserable but didn't want the risk of HRT. The very first day I took it, my flashes practically vanished. After a week, I just get a little warm maybe once or twice a day. The first day or two taking Effexor I experienced a little nausea and tiredness but it has since stopped. I take the 37.5 mg dose once a day. My only regret is that this wasn't offered sooner."

10 / 10
Was this helpful?YesNo
35 Report
  • solar...
  • Taken for 1 to 6 months
  • November 18, 2016

"My PCP put me on 37.5 venlaflaxine for hot flashes and anxiety. She did not want to give me the estrogen patch, which is what I hoped for, because she was concerned about my anxiety. The drug worked in 2 days on the hot flashes, eliminating them completely. Also, my appetite dropped and I lost 20 pounds in the five weeks I was on it. My anxiety improved a bit, but unfortunately, the drug caused me to feel jittery and disassociated from my body. I decided to dump the drug and get the patch from my OB-gyn--best thing I ever did. I feel AMAZING and NORMAL and haven't gained an ounce back three weeks later. I do not have my uterus anymore, so my risk is low. So glad I listened to my body!!!"

6 / 10
Was this helpful?YesNo
38 Report
  • Sunny...
  • August 13, 2008

Effexor XR (venlafaxine) "This drug decreased my hot flushes by 2/3. I figured it would be 100% but that was probably an unreasonable expectation. I've gone from 8-12 a day to 2-3. I've suffered hot flushes since 1998 and the past 6 months they have only gotten more frequent and very annoying. My husband says I'm nicer to live with after taking Effexor, so now I realize I really was irritable from the lack of sleep and night sweats this past year. I tend to forget names or words more frequently but am not sure if the foggy brain has another cause. "

8 / 10
Was this helpful?YesNo
65 Report
  • Karlah
  • Taken for less than 1 month
  • October 23, 2017

"OMG! Only been taking venlafaxine 2 days and it has really cut down on my annoying hot flashes!!!!!! Used to have at least 10 a day and now in 2 days I’ve only had 3!!!!!! Awesome! Who want HRT and cancer possibilities! Thanks to my doctor who prescribed venlafaxine!"

10 / 10
Was this helpful?YesNo
34 Report
  • Karks
  • Taken for 1 to 2 years
  • April 28, 2020

"What a hideous drug. Do not take this for hot flushes EVER. I’d much prefer hot flushes than this wretched feeling of......well, depression! I’ve gained a lot of weight and have not felt settled in life, which was not the case for me before. I had a better time experiencing menopause whilst having chemotherapy and wish I’d never started on this. Have weened myself off with help from doctor. It’s only taken a few weeks. I’ve taken 3 extra days off work after the weekend so I could relax and sleep if need be. I’m doing well and won’t be taking them ever again. If it wasn’t for my doctors kindness one day when I stopped cold turkey, I might not have made it at all."

1 / 10
Was this helpful?YesNo
23 Report
  • Kayla
  • February 18, 2016

"I'm 28 and had a hysterectomy in August of 2015. I was put on Effexor 75mg in September and my hot flashes went away after taking the first dose.. I have gone some days and missed a dose here and there and have felt the withdraw side effects from doing so. Nausea, headaches, flu like symptoms... Recently I have been getting hot flashes more frequently so I'm thinking of upping my does age to 150mg. Any advice????"

9 / 10
Was this helpful?YesNo
38 Report
  • Anonymous
  • August 16, 2010

"I've been on venlafaxine for only a week for hot flashes but it's making me feel sleepy during the day and right out during the night. I'm on the lowest dose. I also am constipated and have a dry mouth from time to time. "

4 / 10
Was this helpful?YesNo
55 Report
  • Baker
  • Taken for 2 to 5 years
  • November 25, 2016

"I have tried everything I can read about to alleviate hot flashes. I'm 47 and have had them for years but still have regular period so I can't try HRTs yet. Nothing over the counter has ever worked. What has worked for me (birth control, Effexor 37.5 & Effexor 75) work for about a year and then the hot flashes come back as strong as ever, all day every day. I'm scared to up my Effexor to 150. Right now, I am trying combination birth control and Effexor 75. It's been a week and no improvement yet. But Effexor did work for me and I'm thankful for the years it did. I had no side effects. It helped my anxiety too."

7 / 10
Was this helpful?YesNo
35 Report
  • Feels...
  • March 19, 2023

"I was prescribed this medicine for hot flashes. I have never been on an antidepressant before. I’ve been standing up on my feet working as a hairdresser for 32 years I have aches and pains which I’ve always been trying to be on top of but one of the first things I noticed when taking this medicine was that my physical pain went away. My hot flashes probably went to half as intense and the terrible drop of mood in my head went completely away I’m only on day four. My first two days were difficult I have to be honest I felt sedated and depressed but once I got one good night's sleep it was like a whole new planet I was living on. It’s raining and I had enough gumption to get dressed and go take an hour-long walk out in the rain and I was damn near skipping. I’m only on 37.5 mg and so far so good!"

10 / 10
Was this helpful?YesNo
9 Report
  • Gigimc
  • Taken for 1 to 6 months
  • July 28, 2017

"This drug did help with hot flash but BEWARE! It's horrible if you miss a dose or and when you need to get off of it. Brain 'zaps', dizziness, crying jags, depression, and more can last for months, even when you ween off according to directions. The withdrawal is horrendous. Please be very thoughtful before you decide to take this drug."

3 / 10
Was this helpful?YesNo
31 Report
  • PugMug
  • May 11, 2016

"The generic medication does not help my hot flashes. I'm taking 37.5mg twice daily. The brand worked so much better, but the price went up dramatically. I really don't want to up the dosage, but these hot flashes are happening too often now. So, it's higher dose or live through the hot flashes. Hot flashes will not win."

2 / 10
Was this helpful?YesNo
34 Report
  • Anonymous
  • Taken for 1 to 2 years
  • December 27, 2019

"I was prescribed venlafaxine for the hot flushes I was having after having a hysterectomy due to estrogen positive breast cancer at the age of 34. I also was on tamoxifen which made the hot flashes even worse. It worked for a while but please do your research. The first two weeks were horrible with nausea and dizziness. Also no one told me how bad it was to come off of the drug. I experienced the worst vertigo and nausea. I would have never taken it if I’d known."

2 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • Taken for less than 1 month
  • October 20, 2019

"I am 49 years old and have experienced hot flashes and other perimenopausal symptoms for over a year including mood swings loss of energy and irritability. After researching hormone replacement therapy and trying homeopathic remedies I decided to try Effexor for multi symptom relief. I have found it to be immediately effective for relief of hot flashes and irritability. Effexor has not only eased my hot flashes but has stabilized my moods and helped me feel like myself again. Having said that it is not a miracle drug. I also have to cognitively work on my irritability when it arises but the Effexor helps me to manage the symptoms much better. The only side effects I have experienced from Effexor is a mild feeling of fatigue."

10 / 10
Was this helpful?YesNo
21 Report
  • Lara...
  • December 1, 2019

"Feb 18, started on Venlafaxine 37.5 mg & took 2 weeks to decrease severity of my hot flashes (15-20 a day). Flashes never left but diminished. After 6 months flashes increased again so doctor upped dosage to 75 mg. Flashes decreased but side effects became more pronounced. Constipation was horrible. Tickley cough every night, brain zaps, gained 10lbs & my libido was gone. Oct 19, after 1 1/2 years, stopped cold turkey. Was so tired of constipation & not being myself. 2nd day off drug, flashes became sweats and 3rd day couldn't function. I felt fluish with withdrawal. I didn't care, just wanted this drug out of my body. Its been 4 weeks & flashes are still around but less severe BUT I have my life back, the constipation is gone, no coughing, no brain zaps, weight is coming off because I am focused & I have my love life back. On the drug I didn't know if my hot flashes were diminishing or not. The drug is an option but would limit how long & I wean off for sure."

7 / 10
Was this helpful?YesNo
20 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Hot Flashes

Symptoms and treatments