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Effexor for Major Depressive Disorder User Reviews (Page 3)

Effexor has an average rating of 5.8 out of 10 from a total of 60 reviews for the treatment of Major Depressive Disorder. 47% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Effexor

  • druge...
  • Taken for less than 1 month
  • April 6, 2022

"My doctor prescribed this medication for MDD (I didn't realize I had that) plus nerve pain, muscle pain, anxiety. She told me it was in the same family as Cymbalta and I told her I had an anaphylactic shock when I took Cymbalta. She said it wasn't the same as Cymbalta and said she would prescribe a very low dose. Needles to say, I ended up in the ER with anaphylactic shock. If you are allergic to another drug within the "same family" as this I would opt not to take it."

1 / 10
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3 Report
  • Vinny
  • November 24, 2021

"I believe I am severely allergic to effexor. I took it for about a week and for that entire week, I did not take a normal poop. I had insanely painful diarrhea, that looked like someone had set up a broken coffee machine over the toilet, day in and day out. I'm sure it has it's merits as a drug, but I was not even able to take the minimum dose for more than a week."

1 / 10
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3 Report
  • Bunsdad
  • Taken for 1 to 2 years
  • June 21, 2017

"Effexor I have tried many drugs but found that "in my case" they are not necessary. I went for an ultrasound on my carotid vein. The doctors said the flow was in the normal range but you could see that they were narrow. I went out of country to have them widened... No more anxiety and depression....drugs are cheaper and more profitable than minor surgery. I will return for stents. "

8 / 10
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5 Report

Frequently asked questions

  • PhxBarb
  • Taken for 2 to 5 years
  • March 9, 2022

"I was on Zoloft for many many years and doing very well. Occasionally I would have down days, nothing serious. Then I took the Covid vaccine (Moderna) and the med just quit. So my PCP gave me Effexor, first 75mg, then 150 mg and it was great. Lasted until I started on Humira for rheumatoid arthritis and now I am getting little help from the Effexor. I am going to quit the Humira and see if Effexor returns. Hoping and praying."

8 / 10
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2 Report
  • PAUSTIN
  • Taken for 10 years or more
  • May 19, 2024

"Effexor really helps with my depression. I tried going off of it because it makes me extremely tired, but I experienced agitation, increase in anxiety, and could feel my depression. I stayed off for 3 weeks and have now resumed taking it. I just wish I wasn't so tired and could sleep more when taking it. I will say I have less emotion when taking this medication and often feel as though I am observing life, not experiencing it."

10 / 10
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0 Report

Are you taking this medicine?

  • cowbr...
  • Taken for 2 to 5 years
  • September 2, 2014

"I use venlafaxine for major depression and to help with migraines. When on it my headaches have decreased."

10 / 10
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25 Report
  • Anonymous
  • Taken for less than 1 month
  • November 22, 2023

"After 5 doses, my anxiety is subsiding and I slowly am engaging in activities of daily living instead of staying in bed."

9 / 10
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3 Report
  • tammy...
  • Taken for 1 to 6 months
  • December 28, 2014

"Very helpful medicine."

8 / 10
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17 Report
  • Zoogie
  • Taken for 2 to 5 years
  • July 27, 2015

"I have been on 225mg for four years and I've liked it for the lack of side effects. Now I think it isn't working well. I'm kind of worried about 300mg."

9 / 10
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14 Report
  • Racky
  • Taken for 10 years or more
  • December 22, 2018

"I've been on effexor for 15 years. 6 months ago the hospital put it up to 375mg. Now it seem's that dose is no longer working for me. I also feel afraid to change drugs after being on it for so long."

7 / 10
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9 Report
  • Kjs
  • Taken for 6 months to 1 year
  • August 17, 2017

"I have a significant loss of motivation but this is not new. Effexor has not helped this symptom."

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10 Report
  • MDewey
  • Taken for 5 to 10 years
  • January 25, 2017

"This drug seems to have helped. I've just gone up to 225mg. Profuse sweating and the rapid withdrawal are the worst."

5 / 10
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9 Report
  • flora...
  • Taken for less than 1 month
  • September 2, 2021

"Honestly just did nothing for me. I waited weeks to feel any kind of effect and it never worked. Probably something to do with my personal brain chemistry!"

1 / 10
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3 Report
  • Mark
  • September 8, 2021

"I'm on it right now and I stop taking it I was so emotional and had breakdowns all the time more than normal"

2 / 10
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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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