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Ursodiol for Primary Biliary Cholangitis User Reviews

Brand names: Actigall, Urso, Reltone Urso Forte

Ursodiol has an average rating of 9.2 out of 10 from a total of 18 reviews for the treatment of Primary Biliary Cholangitis . 94% of reviewers reported a positive experience, while 0% reported a negative experience.

Ursodiol rating summary

9.2 average rating out of 10

18 ratings from 19 user reviews.

Compare all 13 medications used in the treatment of Primary Biliary Cholangitis .

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Reviews for Ursodiol

  • Bev...
  • Taken for 1 to 6 months
  • March 11, 2019

"Have only been on ursodiol for about two months, so I am still in the early stages of any side effects. I have noticed what appears to be some hair loss, dry skin, and maybe some swelling around the lower part of the ankle on my right foot. I was originally put on 300 mg tablets. Humana would not pay for it. I did some research and found they would pay for the 250 mg or 500 mg. No one seems to know why they will not pay for the 300 mg. I talked to my doctor, and she put me on three 250 mg tablets a day. My insurance is covering that, minus my copay. Waiting to have additional blood work to see if the drug is working on my elevated lab levels. For those like me prescribed ursodiol, make sure you check closely with your insurance on dosage coverage they will pay. I only found out about the dosage difference in payments by doing some research. I pray this is my wonder drug."

8 / 10
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55 Report
  • Luc...
  • Taken for 10 years or more
  • August 29, 2019

"I was diagnosed with stage 2 PBC (primary biliary cholangitis) eighteen years ago. I promptly went on Actigall and was switched to Ursodiol about a year later. My recent tests show me to still be in stage 2. This drug seems to have stopped the progress of the disease with very few side effects. I take two pills per day. If I forget to take my morning dose, I am dead tired by midday-a great reminder to take it on time."

10 / 10
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46 Report
  • Sho...
  • Taken for 10 years or more
  • June 10, 2020

"Had routine bloodwork and found that liver enzymes were elevated. Did all kinds of tests, even a liver biopsy, and couldn't find anything. Specialist wanted to try ursodiol 500 mg two times a day. Within months, numbers came back to normal. He wanted to cut back to 500 mg once a day, and I did, but enzymes started rising again. I've taken meds now for 14 years. No side effects that I've noticed. Only thing I can figure is I must need it. Can be pricey, but have to have it. Lifesaver for me."

10 / 10
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38 Report
  • JLS...
  • Taken for less than 1 month
  • February 19, 2019

"I was diagnosed with PBC (Primary Biliary Cholangitis) in November 2019. My ALP was up to 390, and ALT and AST were elevated as well. After three months on Urso (300 mg - three tablets a day), my liver enzymes have improved significantly. My ALP is now down to 209, and my ALT and AST are in normal levels. Urso is a lifesaver!"

10 / 10
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41 Report
  • Anonymous
  • July 29, 2008

Urso (ursodiol) "I was diagnosed with PBC-Stage 2 in February 2008 and started taking URSO. I was sent to Baylor a few weeks later, and their tests indicated I had a negative AMA! They asked me to stop taking URSO to see if weight loss alone would improve the condition. I was off URSO for 4 months and lost 25 lbs. My AMA count is higher now than ever, so I am going back on URSO this morning. It is very obvious to me that URSO put my antibodies to sleep while I was on the drug. That is why my doctor put me back on it today."

10 / 10
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68 Report

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  • PBC...
  • Taken for 2 to 5 years
  • October 31, 2018

"I have been taking this medication for 3 years now. When we figured out what was wrong, I was already at a stage 2 liver disease (only 4 stages before transplant needed). My liver enzymes have been perfect. What a great medication for the primary biliary cirrhosis. I have a few more years. I have no insurance right now and cannot afford the medication, so 2 months without it. Cost without insurance is $400 for 1 month."

10 / 10
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29 Report
  • jel...
  • Taken for 5 to 10 years
  • February 12, 2016

"I am researching the reason for the steep increase in Ursodiol. I have Medicare Part D prescription coverage. Last year, a 90-day supply of Ursodiol (300 mg x 4/day) cost $218.xx for 3 months. That was with Health Spring insurance. This year, I have Silverscript (CVS); they have increased the price to $839.xx for the same quantity, which is $280/mo. That is a 300% increase. Apparently, suppliers - Blue Cross and CVS - have increased the price just because they can. It is indicated on my receipt that the retail cost of the drug is $2,135, so Silverscript says it is saving me $432/month. Silverscript moved the drug from Tier 4 last year to Tier 5 this year. Can anyone give me an honest answer why? BC did the same thing."

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36 Report
  • ber...
  • March 5, 2009

Urso Forte (ursodiol) "I find Urso has helped me a lot. I do have loose bowels with it sometimes. I also found out if I skip a dose and take two Urso's at once, that's when I have bowel movement problems. I quit doing that. I do know it's prolonging my life, for this, I am thankful."

10 / 10
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54 Report
  • con...
  • Taken for less than 1 month
  • September 25, 2024

"I've only been on it for 2 weeks; it stopped my itching that was feeling down to the bone itch! I do feel that it is giving me lower back and side ache, but it's not as bad as the itching. I go for my blood work in 2 weeks and I'm hoping it brings my mitochondrial levels down! I will update this after my blood work! I pray for everyone that has this. It's not easy living with fatigue and all other problems from the liver issues! Prayers for everyone!"

8 / 10
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1 Report
  • Ter...
  • Taken for 1 to 6 months
  • March 29, 2023

"Ursodiol has proven to be a great medication for my PBC. Luckily I have Kaiser insurance and only pay under $20 for a three-month supply. The only setback with Ursodiol is the small weight gain and very little itching, but I am thankful that my liver enzymes are normal again."

10 / 10
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5 Report
  • 20-...
  • Taken for 10 years or more
  • January 29, 2022

"Wonder drug! When I was diagnosed with Primary Biliary Cholangitis (PBC) at stage 2, it was thought that most like me would need a liver transplant within 20 years. Now, 20 years later, I am still at stage 2 due to this drug. If I miss one of my two 500 mg pills per day, I am so exhausted I have to go to bed. I have had no side effects; my only complaint is the cost. Over the years, the price of this easy-to-produce generic has skyrocketed into the hundreds per month simply because the drug makers can do it."

10 / 10
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7 Report
  • liv...
  • June 25, 2008

Urso (ursodiol) "I've been taking four Ursodiol tablets a day for many years. My liver enzymes have stayed normal. Biopsy showed Stage 1."

10 / 10
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97 Report
  • Anonymous
  • August 10, 2009

Urso (ursodiol) "I've been taking Urso for 6 years. My blood levels are now in check. Original biopsy showed stage 4-5 liver damage. Found when I had gallbladder removal surgery."

10 / 10
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58 Report
  • koo...
  • Taken for 10 years or more
  • May 30, 2020

"I find this drug very expensive. Are there any options? I started taking ursodiol 34 years ago."

10 / 10
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15 Report
  • Wee...
  • September 10, 2017

"The meds have helped me feel better and clear my skin discoloration and itching."

8 / 10
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20 Report
  • Pos...
  • Taken for 10 years or more
  • September 10, 2015

"Positive results, but what about the tremendous price increase over the past year and a half?"

9 / 10
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22 Report
  • Tra...
  • November 27, 2008

"The medication seems to work, but it also seems to cause bothersome itching. However, you have to do it to get the GGT levels down."

8 / 10
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30 Report
  • jpr...
  • Taken for 1 to 6 months
  • August 16, 2021

"Husband was taking Ursodiol for Primary Biliary Cholangitis PBC for two months until hands were swelling and unbearable itching."

5 / 10
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4 Report
  • Mr ...
  • Taken for 1 to 6 months
  • March 27, 2024

"I have taken ursodiol for 5 months for PBC and pay under $10 a month. My liver enzymes have lowered a great deal, but kidney numbers have gotten worse?"

10 / 10
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0 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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