Parnate User Reviews & Ratings (Page 4)

• 321
• Taken for 1 to 6 months
• May 25, 2023

For Depression "I have been on over 15 different medications over 30 years, and nothing has helped my PTSD or depression. Parnate has made it worse. I am tired mentally and physically and my suicidal thoughts are turning into end-of-life plan! I have begged for a drug that's new and newly approved which will help my medical pain and mental health or at least in studies. This drug is being used under supervision but I live alone. (There are places that will take me but my psychiatrist I feel isn't hearing me or how serious I am). I'm 64 years old and in ill health. I'm sincerely not living...I exist only with no family support. 30 years of different meds is enough and hope is fading! Treatment Resistant Depression is exactly that and nothing helps me. Parnate is the worst I've been on and I am now stuck because of side effects if I go straight off them..but then again I guess nothing left to lose."

• mike2u
• Taken for 10 years or more
• January 6, 2023

For Depression "I have suffered from chronic depression for years and tried multiple medications. My doctor suggested trying Parnate and it's changed my life. I have had no food issues while taking it but have had problems with over-the-counter antihistamines. This drug really works, wish it was cheaper but it is worth it. Note: generic does not work for me. Hopefully, it will for others."

• megla...
• March 26, 2014

For Depression "I have been on Parnate for about 3 weeks. Am finding the insomnia really hard, as in the day I can be really tired, like fatigue at times and am unsure whether this is coming from switching medicines. Zoloft to Parnate, or from just the Parnate, and not being able to sleep properly. "

• Just...
• Taken for 1 to 6 months
• February 7, 2016

For Depression "I have found that people around me say that I have improved and seem better yet, inside I still feel like I'm in a deep dark hole. I've only been on 40mg for 3 months however. As for increased sex drive!?! When does that happen? It's killed my sex life. Have lost a lot of weight due to food restrictions, but needed to shed a few kilos. I also find it messes with my bladder. Anyone else have this issue? Some days I can pee no problems, others, it's just painful and I struggle to pass urine even when busting to go! Though after reading others stories, it gives me hope, that this drug, will bring me out of the darkness...... As I'm really over being in here. (I had a nervous breakdown)."

• Marty
• Taken for 5 to 10 years
• November 21, 2021

For Depression "After using anti-depressants for 20 year's with minimal success, my psych put me on Parnate in combination with Seroquel. I take the max dose of 120 milligrams though I'm diagnosed with major depressive disorder, severe anxiety, PTSD. When my depression and anxiety kicked in it tended to manifest itself into OCD and compulsive thinking. After 2 weeks my symptoms were almost non existent, and since my state of mind has been a god send. Insomnia can be an issue at times but that's the only negative effect I've had. For anyone who has tried and had no success with other medications, asked your health professionals about Parnate. It was developed in the 70's and only prescribed as a bit of a last resort where other medications haven't worked. For me it's been a wonder drug. In Oz (Australia) the drug is on the PBS schedule of drugs meaning the price is substantially subsided by the government"

• Emdubya
• Taken for 10 years or more
• November 10, 2022

For Depression "I'm torn between a positive review and something less optimistic. I've been on and off Parnate since 1982. Now that Nardil is gone I'm unable to switch between the two if one fails. I take high-dose Parnate, up to 140mg per day. I might get 4 good weeks then a relapse. If I go cold turkey for a week I can reinstate Parnate, and it works ... but never for long enough. I'm on a merry-go-round. No other drugs (antidepressants at least) do anything."

• Isurv...
• Taken for 1 to 2 years
• March 3, 2020

For Depression "I was in acute withdrawal for FIVE YEARS from this dirty drug. The Dr had no clue what she was doing, nor what to do with me. I'm amazed I survived this torture. This is a dirty dangerous drug. I now see there is "Parnate Withdrawal Syndrome", this is an actual thing. Funny how true statistics of what this drug is doing to people aren't being collected???"

• Anonymous
• November 19, 2010

For Depression "Side effects are terrible. They inlcude diarrhea, dry mouth, in my case weight gain, it also made me agitated. I have been trying to withdraw from it and now have neuromuscular symptoms of cramping, teeth grinding, eye blinking."

• Halo
• Taken for 6 months to 1 year
• August 28, 2016

For Depression "Everyone responds differently to medications, and no two people are alike - so I kind of find these forums as being useless (if not borderline ridiculous). But just to share my experience...I have MDD (treatment resistant) along with Complex PTSD. I have tried every medication under the sun (over 90 different meds) before finally being introduced to Parnate in March of 2016. I was initially started at 10mg and eventually moved up to 60mg within 3-4 months. It seemed to be somewhat helpful for my depressive symptoms yet it created so many other horrific side effects along with it, that life is now worse than ever. Never have I been on a med with so many unwanted side effects. I'd rather be severely depressed any day of the week."

• alex_t
• Taken for 1 to 6 months
• November 6, 2017

For Depression "After failing to get any improvement with a whole range of antidepressants (incl. TCAs and wellbutrin), I was very much looking forward to starting on Parnate. Alas, unlike other pills, that had literally zero effect, this one added some negative side effects: heartaches, high BP, tense feeling in the chest, and even a visit to a hospital after I fainted (luckily nothing life-threatening). I envy people whose condition improved though. Also not sure what to do next, as this is literally the last-ditch measure, and ketamine in my country is administered only to hospital inpatients."

• Delaz...
• Taken for 1 to 6 months
• September 17, 2016

For Depression "I have been taking 20mg of Parnate every day for a little over a month now after finally convincing my Psychiatrist to prescribe it. I really can't say how effective it has been in terms of alleviating the symptoms of my depression. Diet restrictions have not really bothered me at all . No real physical side effects apart from extreme sun sensitivity. This REALLY bothers me because I'm extremely fair skinned and burn so easily - frequent, and I mean FREQUENT reapplications of sunscreen and sun avoidance are a must for me. Parnate has also decreased the effectiveness of benzodiazepines such as valium and imovane. This has been really frustrating because I also suffer from anxiety and insomnia."

• Colin...
• Taken for 1 to 6 months
• April 17, 2022

For Depression "Might be good for depression if you like feeling manic and talking way more than usual. Also the hypo-tension and raised liver count was alarming to say the least. If you decide to take it, make sure you get your liver checked monthly, as I was only on it for two months thank God and a low dose of 20mg per day, I had to stop when my blood pressure dropped to 60 over 10 lucky I was in a hospital at the time."

• Fluffy
• Taken for 1 to 6 months
• July 8, 2021

For Depression "I’ve been on parnate 60 milligrams for 2 months. I take medicine for sleep. I’m unable to sleep and still have anxiety. On medication for both. Recently my dr decided to decrease my dose to 40mg. Saying there’s a chemical in it that can cause my symptoms. Can a lower dose help these symptoms? I take klonopin and ambien."

• Lolly...
• October 18, 2019

For Depression "This medication Parnate saved my life!! NO OTHER medication worked. I've been taking it for 5 years and got my life back. Please, please bring it back."

• chester
• Taken for 5 to 10 years
• April 13, 2019

For Depression "Parnate really works for my depression and makes all other drugs for depression look like a joke."

• cloudy
• Taken for 10 years or more
• May 22, 2018

For Depression "Parnate is my favorite antidepressant. It took me from suicidal to happy in less than 48 hours."

• Greg
• Taken for 5 to 10 years
• July 3, 2018

For Depression "Parnate is the only antidepressant worth taking. "

• Anonymous
• Taken for 10 years or more
• June 16, 2016

For Depression "When nothing else works long term, this is the one. Pain to have to watch what you eat since it's an MAOI, but it's better than not having it!"

• JRano
• Taken for 1 to 2 years
• April 13, 2019

For Depression "This medicine literally saved my life. I've tried them all and only the MAOI class of drugs actually work."

• Orkideh
• November 9, 2012

For Depression "It may include some side effects, I used it, and I prefer Parnate with some side effects versus depression. That's my experience."

• Johnny...
• Taken for 5 to 10 years
• November 15, 2012

For Depression "5 years on Parnate. Have tried numerous antidepressants and psycho drugs, this is the only one that has worked. Also take 2 mg/day Suboxone, it helps somehow."

• maiiia
• September 14, 2017

For Depression "A miracle drug for my depression!!!"

• Rosey
• January 6, 2021

For Depression "Parnate was great for depression but it didn’t really help with anxiety at all. Coming off it has been a nightmare! Going to try Nardil next if I can track supply down"

• Heather
• Taken for 6 months to 1 year
• May 3, 2023

For Depression "Drinking milk and other foods is not recommended. It made me so nauseous. Sadly I'd forget and then get sick."