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Tramadol for Restless Legs Syndrome User Reviews (Page 2)

Brand names: Tramadol Hydrochloride ER, ConZip Qdolo

Tramadol has an average rating of 8.8 out of 10 from a total of 125 reviews for the off-label treatment of Restless Legs Syndrome. 86% of reviewers reported a positive experience, while 6% reported a negative experience.

Reviews for Tramadol

  • Pal...
  • Taken for 1 to 6 months
  • October 11, 2019

"I have had RLS as long as I can remember. I am 54 years old. Tried all the normal drugs, creams, gels, etc. Recently had knee replacement surgery, got slow-release tramadol, and no RLS. I stopped tramadol for a bit, and RLS came back, so I am now on it, still for pain in my knee, but it's greatly helping with RLS. It doesn't matter if it's addictive, it's better than living with the awful life of severe RLS, in my opinion."

10 / 10
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  • KDa...
  • Taken for 5 to 10 years
  • June 21, 2019

"First, to reviewers who are telling others to not take Tramadol for RLS, each person's reaction to drugs is different, so please stop. I, too, have discovered that Tramadol stops my RLS symptoms. I have the genetically caused version and have struggled off and on my whole life. I did catch a break from my teens to late 20s, but it came back and grew worse. I also have osteoarthritis in my knees, and it seems when that hurts and/or my legs get cold, the RLS kicks up, but it is not limited to these triggers. I was given Tramadol after knee surgery, and I discovered it relieved my RLS. (I also discovered it helps ease/stop my chronic neuropathic cough.) On Requip and Mirapex, I keep suffering from augmentation over time, and it spreads to my torso, arms, and even my face and happens during the day at work. Tramadol makes it stop so that I can work once it kicks in. With the crackdown on opiates, I am terrified my doctor won't renew my prescription each time I go in for it. What do I do then?"

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  • Dns...
  • April 28, 2008

"I have been taking tramadol for about 3 years for restless leg syndrome. My doctor tried several other drugs for this, and all they did was enhance the problem. I took my first two tramadol and had the best night's sleep I have had in years."

10 / 10
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67 Report

Frequently asked questions

  • Bri...
  • March 10, 2015

"I have 3 herniated discs in my lumbar spine with lower back pain and sciatica. I am currently taking Percocet and Zanaflex for this condition. But recently, I've been having terrible bouts of Restless Leg Syndrome. My doctor has prescribed me Tramadol, and it helps a great deal. My legs no longer feel heavy or achy and like I constantly need to move them. I've been taking 100 mg of Tramadol every 8 hours. It works for about 6 hours, and then I start feeling uncomfortable, but it has definitely been a great help. I would recommend this to anyone suffering from Restless Legs Syndrome. This medicine will help ease your leg discomfort and let you get some sleep."

10 / 10
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  • par...
  • December 9, 2010

Ultram (tramadol) "I have been taking tramadol for over 11 years for RLS, and while I think it works pretty well for my legs, I feel I have to take more than prescribed to get the same amount of relief that I did when I began the medication. I have not told my doctor for fear that she will take me off the medicine. The withdrawal symptoms are horrendous. My legs are 10 times worse when I am coming off tramadol. I get involuntary spasms in both my arms and legs and am extremely moody. It is near impossible for me to sleep without the tramadol. I am not trying to scare anyone away from taking it because I know it has worked wonders for a lot of other people."

7 / 10
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  • Rob...
  • May 1, 2017

"After 20 yrs of ...lotions, showers, walks, yoga, vitamins, etc. I finally found a medication that completely works on my restless leg. I started taking tramadol for my pain in my elbow, but the wonderful side effect was NO PAIN AND NO SYMPTOMS of my restless leg..."

10 / 10
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  • Pal...
  • Taken for 2 to 5 years
  • July 22, 2018

"So similar to others in that I had spinal surgery and was prescribed tramadol for the pain. When I came off the drug, my RLS (restless leg syndrome) was unbelievably bad. My Dr was more than happy to prescribe tramadol and I generally only take it when I get RLS rather than as a preventative measure and normally take two 50 mg tablets. I’ve been using it now for 5 years."

10 / 10
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31 Report

More FAQ

  • Mun...
  • October 26, 2015

"I have had RLS since I was a child, they didn't know what it was then and called it 'growing pains.' I would cry when it rained or was cold, my legs would hurt so bad. Then, 15 years ago, as an adult, I was given Ultram for a neck injury [three ruptured discs], and my RLS just vanished. I couldn't believe it! At first, I kept waiting for it to come back, but it didn't. Now I take tramadol 100 mg three times a day for nerve pain and RLS, and it completely controls the symptoms without obnoxious side effects [like nausea, vomiting, insomnia, and sinusitis from Requip, loss of coordination and falling from gabapentin, headaches, blurred vision, nausea, and flank pain from Lyrica-ugh, those drugs were awful!] I sleep well now and feel rested."

10 / 10
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  • Anonymous
  • April 10, 2012

"Have had restless legs syndrome for 7 years, and my MD tried multiple medicines (Requip, Neurontin, Carbidopa/Levodopa). All worked OK but still had RLS in the day and night. Then, I hurt my back and was put on Tramadol three times a day. My RLS completely went away, but I had problems peeing. So, I went off, and those symptoms went away (but the RLS came back). So, now I take one pill a day, and the RLS is gone, and I have no side effects."

8 / 10
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  • dr ...
  • November 22, 2013

"I really had been suffering from this complex and less studied disorder, which can seriously affect your efficacy. Fortunately, I shifted to a country where no good COX-2 inhibitors were available for my on-and-off back pain, so I was given tramadol 50 mg twice daily. Once I took a cap, after 2 hours I found my legs quite fine and sensation-free, which I used to have for a decade on and off."

8 / 10
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  • lon...
  • Taken for 1 to 6 months
  • June 2, 2015

"I have dealt with RLS for a number of years. I suffer from insomnia, but I would take melatonin, Lunesta, Ambien, and they did nothing but aggravate my RLS worse. Nothing like being tired and agitated because of the constant need to move my legs. I had to have a hysterectomy in April, and they sent me home with tramadol. After a week, I noticed I had not had an RLS episode for the entire week. I didn't take it one night because I wasn't having any pain from surgery... RLS kicked in. Realized the tramadol was keeping the RLS at bay. If I don't take it before the RLS kicks in, it's not quite as effective."

9 / 10
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  • Tuf...
  • November 25, 2016

"I was originally prescribed tramadol more than 20 years ago. I have a severe case of RLS that affects my legs, arms, and torso. Anytime I am at rest, no matter what time of the day, I begin to look like a fish out of water flopping all over the place, and the sensation is unbearable. I have had RLS since childhood and it has steadily gotten significantly worse over the years. If I didn't have tramadol to take care of RLS, I would probably jump off a bridge or shoot myself, IT IS THAT BAD WITH ME. I am always at the mercy of my doctor for a script now that it has been reclassified with the FDA and is now listed as a controlled substance (thanks to those who abuse medications)."

10 / 10
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  • Vir...
  • Taken for 5 to 10 years
  • August 26, 2016

"Was given Tramadol for back pain and stiffness, then realized it helped my RLS. Now my doctor wants me off of it because she said that it is not known to treat RLS. I was taking two tablets in the evening. Now she has me trying Ropinirole HCL. I am recovering from a hip replacement and doing so well until my doctor took me off the Tramadol, now I am exhausted and feel like I am not progressing with recovery. Don't want to go anywhere or do anything. If I was taking 200 tablets a week, I could understand their concern, but I am taking 14 tablets a week. After reading everyone's comments, I plan on talking to my doctor to inform her that there are people using Tramadol with success. Maybe there is hope!"

10 / 10
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  • gos...
  • Taken for 2 to 5 years
  • February 2, 2015

"I have had restless leg for quite a few years and was on Oxycodone for pain and noticed it helped the restless leg at night, but a friend had me try tramadol and it worked well. I told my doctor, and now I take it at night, 100 to 150 mg."

9 / 10
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  • Mrs...
  • Taken for 2 to 5 years
  • May 23, 2013

"I was given 50 mg of tramadol 3x a day, initially for restless leg syndrome. This, combined with gabapentin, has helped so much with restless leg syndrome. I also have chronic hip pain and have been dealing with it since I was a young child due to my hips dislocating multiple times a month. This medicine works well, but I have had to have my doctor up the dose. I now take 300 mg a day. I do have to say that the side effects are terrible. I itch horribly! My whole body, but the worst place is my face! It also has made it so that I am unable to sleep at night. It's worth it to not be in pain and to lay down comfortably, but the side effects for me are bad."

8 / 10
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  • Mik...
  • September 1, 2015

"Had increasing bad RLS experiences before I knew they were RLS, so I just suffered through them. Then was given tramadol for pain for a shoulder injury and noticed leg problems stopped. When I stopped tramadol for pain, the RLS returned. That was 8 years ago, and I have been taking it for my RLS ever since, and it's a lifesaver. It never fails to make the symptoms stop or appear in the first place. Tramadol has worked great for me for RLS."

9 / 10
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  • Gui...
  • December 21, 2014

"I've suffered from restless leg syndrome since 2nd grade. It is a miserable affliction. I am now 51, and I experience it in my legs, arms, and back as restlessness and pain starting after 7 PM. Initially, I was on ropinirole and pramipexole for a few years. Those pills made me feel sleepy until 3 AM, at which time I'd wake up. A sleep specialist now has me on 1200 mg of gabapentin and 50 mg of tramadol. For me, this combination works great. It relieves 100% of the restlessness and 90% of the pain and other uncomfortable sensations. I've been able to fall asleep with this medicine combination. Glad it's available!"

10 / 10
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  • Mac...
  • Taken for less than 1 month
  • May 13, 2016

"I am 25 and struggle with RLS, it is horrible! I'm always tired, barely sleep, and am down a lot due to lack of sleep. When I finish work, I can't relax or unwind. I have tried everything! Tramadol is the ONLY thing that works for hours (a bath can last about 20 mins). They relax me, and after about half an hour or so, I don't have that horrible feeling in my legs. If you have RLS, try this, it works wonders for me."

10 / 10
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  • Joh...
  • Taken for 5 to 10 years
  • October 4, 2019

"Have had RLS for as long as I can remember. It affects my legs, my arms, and shoulders. Used to dread nighttime, as I knew as soon as I tried to sleep, the RLS would kick in. Tried everything, including alcohol, which worked for a short while. Nearly became an alcoholic, to tell the truth. Then I discovered tramadol, as long as I take the tablets daily, it keeps RLS at bay."

9 / 10
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  • Ric...
  • Taken for 10 years or more
  • July 26, 2023

"It's frustrating and demoralizing to have the medical community not listen that Tramadol is a treatment for RLS. As a long-term sufferer of RLS at night only, I've tried all the medications that are labeled for RLS, endured numerous sleep studies and neurological testing. Some medications have even made it worse, Ropinirole for example. Additionally, I find it utterly bizarre that the medical community is willing and extremely eager to place me on medication such as an antidepressant which I've shown adverse mental reactions to instead of the medication that has proven results for over a decade. I understand the opioid epidemic argument, as well as concerns of long-term use of opioids. However, the medical community doesn't know exactly how antidepressants work for RLS, yet enthusiastically prescribes them as if they're harmless. RLS has diminished my faith in the medical community. Tramadol needs to be labeled as a treatment for RLS sufferers."

10 / 10
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  • jjy...
  • Taken for 1 to 6 months
  • August 9, 2016

"I have severe restless legs-have had them since I was a kid. I used to just be very restless and couldn't keep my legs still, but now decades later, I also have lots of pain in my legs along with the horrible restlessness. Anyway, I've tried benzos, antidepressants, sleeping pills, Requip, Horizant, Neurontin, and many natural remedies in the form of creams and supplements. The ONLY thing that has worked for me is tramadol. I only take 50 mg 30 min before bed, and it gets rid of both pain and restlessness. I've read all the negative stuff regarding tramadol but feel that at this low dose it's worth sleeping at night. I have also recently looked into a vibrating pad called 'Relaxis'-it's expensive and needs a prescription to get this."

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  • Mic...
  • Taken for 5 to 10 years
  • October 20, 2022

"Tramadol saved my life. I was suicidal because no meds worked on my RLS. Lack of sleep is torture. Now my doctor says she will no longer prescribe it, even though it's worked perfectly fine, with no addiction or side effects. I'm afraid to have to go through all the other RLS drugs again that I already know do not work on me. What can I do? I feel like I'm being victimized by my own doctor."

10 / 10
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  • JWG...
  • April 8, 2012

"Fantastic. I finally got immediate relief for my restless leg syndrome after suffering for many months and taking other medicines like Horizant. This one did the trick for my legs, and I sleep well again."

10 / 10
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  • Mom...
  • February 16, 2018

"I've had RLS for years. I am a retired UPS driver, and all the walking would bring on such severe issues with this I couldn't even watch TV. I had a knee replacement after retiring and used tramadol for pain. I realized I wasn't suffering the same issues with RLS! I've taken everything out there, with some only making the symptoms worsen! I wished it wasn't on that dreaded narcotic list and hate that it is an opioid! I take two 50 mg at night before bed. I am so cautious about being an opioid junkie but not so sure anything out there will work. I've tried most all of them."

10 / 10
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  • jac...
  • March 2, 2011

"I am unaware of any severely adverse reactions regarding the use of Tramadol. I use 50 mg two to three times per day for arthritic pain and for restless leg syndrome. I have also found that the more you use your back and legs during the day (exercise, walking, biking, running), the less symptomatic the restless legs syndrome is. Perhaps there is a connection between the neurological pathology of RLS and exercise. Maybe the increase in endorphins caused by exercise has something to do with it. Sorry, I digress. In the meantime, when RLS is symptomatic, Tramadol is a godsend. Tramadol is quite effective as well for arthritic pain. I wouldn't take anything else."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Restless Legs Syndrome

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