Skip to main content

Tramadol for Anxiety User Reviews (Page 2)

Brand names: Tramadol Hydrochloride ER, ConZip Qdolo

Tramadol has an average rating of 9.3 out of 10 from a total of 104 reviews for the off-label treatment of Anxiety. 92% of reviewers reported a positive experience, while 2% reported a negative experience.

Reviews for Tramadol

  • talari
  • Taken for 1 to 6 months
  • September 23, 2015

"When I was prescribed Tramadol for abdominal pain, little did I know about the bonus effects. I was able to lose 20 lbs in 3 months (less appetite). My mood became so good, and I got my joy of life back. I took 50 mg daily. I felt less anxious and depressed. Mostly, I cared less about what people think of me. I started to swim and hike. My mom, who is against pills, said 'you changed so much, whatever that you do, keep doing it'. I'm a 45-year-old male."

10 / 10
Was this helpful?YesNo
108 Report
  • Missy...
  • March 2, 2016

"I was prescribed Tramadol for back pain because I am allergic to NSAIDs. I was taking two 50mg tablets per day and noticed that my mental state also improved while taking this medication. My anxiety subsided and I found that I did not get upset even in stressful situations (I work in HR which is very stressful for me). It's been a miracle for me since I deal with anxiety issues almost daily. It puts me in a state of calm, but I'm still me. The only side effects I've experienced while taking Tramadol have been entirely positive. I wish it was prescribed for anxiety disorders."

10 / 10
Was this helpful?YesNo
100 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • September 21, 2012

"Really great medicine for my anxiety. Originally, my doctor prescribed this for pain, but I find it's better for anxiety. Be careful, and when you need to stop taking the medicine, you need to taper off very slowly, or else it could be very uncomfortable. Withdrawal syndrome is very uncomfortable, and you need to taper off."

10 / 10
Was this helpful?YesNo
121 Report

Frequently asked questions

  • Alex
  • Taken for 1 to 6 months
  • October 25, 2014

"All I have to say about Tramadol is WOW. I'm 19 and have had mild depression associated with anxiety, as well as hyperhidrosis (excessive sweating). I've tried Zoloft and Lexapro for my depression/anxiety, and also have used Benzodiazepines (Xanax, Klonopin) in the past. The antidepressants did nothing, and in fact made my symptoms worse. Although Xanax and Klonopin helped, they tended to make my moods shift up and down. Tramadol works AMAZINGLY for ALL of the above conditions! I take 50-100 mg and my mood is lifted, I feel steadily relaxed all day, focused, motivated. My underarm sweating is completely gone, and I feel like I'm getting my life back. It also works great for moderate pain. No side effects! It's a miracle medicine."

10 / 10
Was this helpful?YesNo
104 Report
  • Pixie
  • Taken for 2 to 5 years
  • September 13, 2016

"I have been the guinea pig, like most of us who suffer from anxiety, depression, OCD tendencies, etc. I have tried more 'psych' meds than I care to count. Some did nothing. Some made me physically sick. One made me homicidal. I have never been a fan of narcotics. They too do not agree with me. After herniated disc/back surgery 3 years ago, Dr. said I needed to take at least something. So I got Tramadol. 200mg a day. If I had pain, I was too calm and happy to notice. Life was great! I had energy and focus. I was on this regimen for about 20 days. About the third day into not taking Tramadol, I felt like hell! Talked with PCP who pulled me off Lexapro and now I take this. Do have 0.5mg Xanax for bad panic attacks. I feel amazing!"

9 / 10
Was this helpful?YesNo
88 Report

Are you taking this medicine?

  • Noxy
  • Taken for less than 1 month
  • June 5, 2014

"I was just recently diagnosed with fibromyalgia and was temporarily prescribed tramadol for pain. I deal with terrible anxiety on a daily basis, and it turns out since I've been taking this, it has helped so much with anxiety. Although it's been hard to concentrate while taking this, I don't like the way it alters my mind, but it's been a huge relief to be anxiety-free. I haven't discussed this with my doctor yet, but so far I've found nothing else to help anxiety."

8 / 10
Was this helpful?YesNo
103 Report
  • Anonymous
  • April 7, 2011

"I have been taking Tramadol HCL for severe anxiety and clinically severe OCD. This medicine really works wonders for anxiety, and my psychiatrist has me on this, combining it with Risperdal, Xanax XR, and Xanax IR. But before I combined Tramadol HCL with those other medicines, I was taking the Tramadol HCL alone, and it knocked my anxiety down to more tolerable levels and helped me ignore my obsessions from my OCD more."

10 / 10
Was this helpful?YesNo
121 Report

More FAQ

  • TramFan
  • Taken for 1 to 6 months
  • April 2, 2015

"I was prescribed Tramadol for kidney stones. Took 1 each day and gradually changed. I stopped putting my head down when I left my apartment, trying to avoid eye contact with neighbors. I was actually smiling and stopping to say hello and people were now smiling back and waving. I did not have a knot in my stomach at the thought of riding the subway. I was not cutting short my visits to clients only to return after hours and to work so I could avoid being around people. I felt happy and I was not ready to fight with the first person that bumped into me on the street. It was as if something in me was broken and Tramadol somehow fixed it. All the bad things are back, and I want more Tramadol, but I can't get it. Thinking of asking a doctor."

10 / 10
Was this helpful?YesNo
91 Report
  • Anno...
  • Taken for 5 to 10 years
  • July 6, 2017

"I have chronic anxiety and have tried many serotonin-type meds over a 15-year span and have also suffered from depression. I had a very bad reaction to the meds. Being in hard labor, I worked all my life - Concrete-Tree removals - Underground utility work - Water main repair, etc. I have had numerous injuries to my back, neck, knees, hands, and shoulders. I've broken many bones (comes with the territory). I was diagnosed with Degenerative Disk Disease and was prescribed Ultram 50 mg. I got up to 400 mg but now down to 300 mg, and what a difference! Not just with pain, but my anxiety was reduced by at least 50% and depression was gone. My alertness increased, and my mood was elevated. I will try to stay on the medication for life. Walmart had the med for $4-$12 if no insurance."

10 / 10
Was this helpful?YesNo
72 Report
  • Anonymous
  • August 17, 2011

"It's the only thing that ever helped, but you build a tolerance. If you stop for a few days, which is hard but not impossible, it works just like it did before. I tried all the normal SSRIs, SNRIs, and benzodiazepines; nothing worked like this. It's the best yet."

9 / 10
Was this helpful?YesNo
110 Report
  • Alex
  • September 2, 2019

"I have been taking tramadol for pain for the past two months. In the past I have struggled with anxiety and depression , but since I've been taking tramadol, I've felt great. It really takes the edge off, and I would rather take tramadol than all the other meds rather I've been prescribed before for anxiety. I have no side effects with tramadol, and I'm worried about what I'm going to do when I run out."

10 / 10
Was this helpful?YesNo
53 Report
  • Fatal...
  • June 8, 2016

"I had two very old bottles of Tramadol stashed away because they never really worked for pain. One day I had significant enough pain that I decided to give them a try again. Again, it didn't do anything for the pain. I did notice, though, that my entire outlook on life had drastically improved. It didn't make me 'high', but it alleviated my extreme social anxiety and made me feel positive and upbeat. When I am often a person who is disappointed about waking up each day. My son could tell when I did or didn't take it because he notices a dramatic difference in me. I used the ones I had wisely until I ran out. I researched online to find that I was far from being the only person who has had this experience, so... (to be continued)"

10 / 10
Was this helpful?YesNo
77 Report
  • Telem...
  • Taken for 2 to 5 years
  • November 12, 2023

"Update. Tramadol 50-100 mg/day continues to provide exceptional relief from depression and anxiety. I am now in my late 60s and suffer from a severe back injury with three discs now completely deteriorated and severe arthritis in my spine, pelvis, and feet. I take 50 mg in the morning and 50 mg, never taking more. Tramadol/Tylenol allows me a good night of sleep with reduced pain and no racing of my brain. In the morning, 25-50 mg of Tramadol. I lost nerve function in my lower right leg due to herniated discs and have an atrophied calf muscle. Tramadol has been an uplifting mental experience allowing me to have a far better quality of life by alleviating the depression and anxiety caused by chronic pain. It is a constant struggle to get refills when my primary doctor moves away. My quality of life has increased since I first began this drug. I have a long-term contract with my physician. It remains the most effective drug against anxiety and depression in my case."

10 / 10
Was this helpful?YesNo
12 Report
  • KakeVon
  • Taken for 5 to 10 years
  • April 10, 2017

"After nearly 4 months off of Tramadol (and, yes, the withdrawal was horrible), I've decided to go back on it. I don't take it for pain any longer; I take it for the brighter outlook it gives me as well as the anti-anxiety benefits. Like some other users, I've been on many antidepressants over the years but nothing really seemed to work, so I'm off of all of the so-called FDA-approved meds. Tramadol isn't cheap (because I don't have a prescription and can't imagine getting one from my doctor for the reason I take it) but it IS cheaper than a visit to my psychiatrist. It makes my life smoother, and I'm simply making the decision to go back to it."

10 / 10
Was this helpful?YesNo
69 Report
  • Theyu...
  • Taken for less than 1 month
  • April 8, 2019

"I have maybe the worst anxiety in the world and I have used thousands of medicines for my anxiety and my panic attacks. I don’t know how but Tramadol works perfectly for my anxiety. Even more effective than Xanax ... omg"

10 / 10
Was this helpful?YesNo
54 Report
  • Cervi...
  • Taken for 1 to 2 years
  • July 17, 2016

"I have a history of migraines & Cervical Stenosis at C6-C7 with bulging of disc causing constant muscle tension in my neck/shoulders. I have a long history of Bipolar D/O, depression & anxiety & recent development of panic attacks (r/t recurrent missed miscarriages). I have been treated with various psych/antidepressants/anti-anxiety meds over the past 23 years. I had been prescribed various meds also to help with migraines to no avail with exception of Maxalt to relieve impending migraine episodes. When I was prescribed Tramadol for migraines & chronic muscle/neck/shoulder pain, I began to see a huge decrease in my anxiety & motivation & wanting to face each day. I too hope they will consider Ultram for the treatment of anxiety/mood disorder."

9 / 10
Was this helpful?YesNo
73 Report
  • Hopeful
  • Taken for 6 months to 1 year
  • September 19, 2014

"I recently was diagnosed with BPD. I have suffered from depression, fear of abandonment, and suicidal ideologies since I was a teenager. Last October, I had a total left knee replacement. The surgeon put me on tramadol, up to 8 a day. I never took that many, but I did notice a change in my mood and depression. While not a panacea, tramadol (50mg) 2x a day has made a significant improvement in my symptoms, especially since I am going through a breakup with my significant other."

7 / 10
Was this helpful?YesNo
84 Report
  • Sticky
  • April 30, 2020

"I never usually respond with comments but feel I must in this case as a duty to help others with anxiety. I realise there are different forms of anxiety? I too suffered anxiety for about 30 years. I exercise regularly, run, cycle, meditate, gym work, eat all the recommended foods...all the "right things". I have been on several serotonin medications which made symptoms worse, almost suicidal, until accustomed after a month. But only partially successful. I had a new knee operation last year and took a Tramadol-Paracetamol combination for pain for a few weeks (37mg Tramadol per pill, 2, pills 3 times daily. Also with the depression/anxiety meds. The anxiety totally disappeared. Now I am on 50mg Tramadol nightly, and no other medication, and I have felt so good for 3 months, and no negative side-effects. I have a new life. I will think about trying 25mg (half tablet) daily My doctor is surprised, but is happy to prescribe based on my feedback !!"

10 / 10
Was this helpful?YesNo
44 Report
  • KW-sc33
  • August 20, 2016

"I was put on tramadol for pain associated with a staph and yeast infection. Not only did it help greatly with my pain but reduced my anxiety and depression to a minimum. I find myself getting things done more effectively and happier when completing my daily tasks, whether at work or at home. I was a daily drinker, and since starting tramadol, I have had nothing to drink, nor do I feel the need to go back to drinking for anything. I am also type 1 diabetic, and tramadol can help lower blood sugars and keep them more stable in my experience. Awesome medication, I take about 100mg daily. I split the 50mg in 2 and take two 25mg doses a half an hour apart twice a day. If I miss a dose or run out, I never have any negative experiences..."

10 / 10
Was this helpful?YesNo
68 Report
  • AddamNN
  • October 4, 2015

"I am on a tramadol dosage of 150-200mg a day for abdominal pain. Been taking it for 2 months now. Little did I know this drug is also an antidepressant. I feel absolutely great when taking it. It doesn't give you the same 'buzzed feel' as a Vicodin or Percocet, however, it puts you in a fantastic mood, relaxes you, and also works nicely on the pain without making you feel groggy or tired. There are some dangers associated with the drug such as seizures, so please only take under the supervision of a doctor you trust. They will know if tramadol is safe for you to take."

9 / 10
Was this helpful?YesNo
73 Report
  • Cat
  • September 20, 2019

"I’ve been taking many prescriptions because I have been through many traumatic experiences. I was given tramadol for low back disc herniations. Wow! It helps with my pain, depression, anxiety as well . I’m allowed to take 100mg 3 times a day. I don’t notice the improvement until the second dose and it’s something I would have to have everyday. Drawbacks for me are constipation and insomnia."

9 / 10
Was this helpful?YesNo
46 Report
  • Che
  • Taken for 2 to 5 years
  • May 16, 2016

"Recently we made big changes in our lives, which set off such a bad anxiety reaction! I have dealt with this on and off for years! I was already on Tramadol for RA and a bad back. I have been on Xanax and was put on other popular anxiety meds, but always noticed how calm my Tramadol made me. I stopped the new meds as they did not do much! If it wasn't for my Tramadol I don't know what I would do. I wish doctors would research this so it be subscribed for anxiety!"

10 / 10
Was this helpful?YesNo
67 Report
  • happy
  • July 29, 2020

"I just wanted to some helpful advice. Tramadol is great for anxiety. The advice I want to give is for anyone that runs out before your refill date. You will have withdrawals during this time period and they suck! No sugar coating...they suck! I came across a forum about a year ago about Kratom as a helpful tool for withdrawals. I was desperate so I tried it. OMG! It is literally a miracle when dealing withdrawal symptoms from tramadol! I can't say this enough! I understand how some people have stopped pain meds all together with it. Its good for pain, anxiety, mood lifting. It attaches to a different opioid receptor, but is enough to keep you from having withdrawal symptoms...and MUCH better for you than prescription drugs!"

8 / 10
Was this helpful?YesNo
39 Report
  • Elocin...
  • July 9, 2013

"I have tried EVERYTHING for my anxiety (my symptoms stem from post-traumatic stress disorder, but have also been labeled as generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety). Nothing has worked (aside from Benzodiazepines, which I avoid because of the sedative effect), other than Tramadol. I take 50 mg a day. Recently, I worried that I would run out, so I tapered off of it, and my anxiety resurged with a vengeance. I never developed any tolerance for this medication - it has worked well for me for a year. The only negative has been when I mix it with alcohol. It didn't have much effect on the social anxiety, but it worked great in general."

9 / 10
Was this helpful?YesNo
83 Report
  • Anonymous
  • Taken for 1 to 2 years
  • April 10, 2017

"Began taking after minor operation to deal with pain. I told my doctor that it had a calming effect and asked if was safe to take to deal with anxiety. Been taking it for about a year. Two to four 50 mg pills per day. Some days I take none. No constipation, no insomnia."

10 / 10
Was this helpful?YesNo
60 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Anxiety

Care guides

Medicine.com guides (external)