Skip to main content

Topiramate for Weight Loss (Obesity/Overweight) User Reviews (Page 5)

Brand names: Topamax, Trokendi XR, Qudexy XR Eprontia

Topiramate has an average rating of 7.3 out of 10 from a total of 204 reviews for the off-label treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Topiramate

  • Skate...
  • Taken for 1 to 2 years
  • January 5, 2020

"I have been on Topamax for one and half years now but the side effects are not worth the benefits. I was prescribed this medication to lose weight caused by my other bi polar medications. It only kept me from gaining weight. Eventually I did gain weight anyway. I was taking 150 mg at night. But it gave me severe depression. I was also so tired on this medication. My job was effected because even the simplest email became a challenge, and holding on conversations was hard too. I just couldn't not finding the words. My memory was greatly changed which was sad for my sons. Now that I am trying with my Dr.s help to ween off I'm having some difficulty."

3 / 10
Was this helpful?YesNo
50 Report
  • Micha...
  • Taken for 1 to 6 months
  • April 20, 2017

"I'm calling this the 'Closer to Perfection Drug!' All since March 13, 2017 - Taking 200mg now - Psoriasis has diminished substantially! - Went from wearing my hubby's 3x to men's L (loose fit shirt too!) - No more migraines but I have a pressure system in my head like old men do in their knees when storms are coming! (Never wrong on this one) - The trick to all this, I work with it. I don't expect the pill to do it all for me. I drink 2-3 liters if not 4 a day and I eat healthy. I have a big protein breakfast and I have a smaller dinner. I exercise. - I have cheat treats but watch my sodium every day. It helps. Take care of your body and it will take care of you in return!"

10 / 10
Was this helpful?YesNo
71 Report
  • Kitte...
  • Taken for 1 to 6 months
  • August 11, 2016

Topamax (topiramate) "I've tried it twice. The first time was about 7 years ago and I lost a modest amount of weight easily. I can't remember how much. It made me thirsty, so I drank a lot of water, and it took away my craving for junk food. The second time was at the end of May 2016. I took 100mg at night. I lost 10 pounds in about 5-6 weeks easily. I had no desire to snack or eat emotionally. The only downside was that I was anxious a lot. I have now plateaued, but at least I'm not gaining weight. I should try to up the dose. At least the anxiety has largely decreased."

9 / 10
Was this helpful?YesNo
75 Report

Frequently asked questions

  • Bipol...
  • September 28, 2015

"I've been on this medication for approximately half a month. I actually suffer from bipolar disorder, depression, and PTSD. Recently, after I retired from fighting mixed martial arts and had knee surgery, I was more depressed and gained weight. I am a big guy anyway; normal for me is 6 ft 6 260 lbs. I got up to 340 and was like, 'Okay, this is enough.' I started my vegan diet that I did back when I fought MMA; I went to the doctor and I was down 10 lbs. I needed a new medication, so she put me on topamax. From day 1, zero appetite, none whatsoever. I have to make an effort to eat. When I do eat, it's just cut-up raw veggies in a bowl of vinegar; that's it for the day. Now I am on top of my supplements, so my body has what it needs. I'm shedding pounds like mad."

10 / 10
Was this helpful?YesNo
79 Report
  • Sky
  • September 20, 2019

"I was initially on this medication topiramate for chronic adolescent migraines for about 6 years and tapered off when I grew out of the condition. I’m back on it again for appetite and weight loss, I started taking the medication at 200lbs, it’s been 3 weeks and I have not been weighed yet by I can already feel a difference. I eat less than half of what I could have before, where I’d eat 2.5 servings of a meal I eat 1 and I am satisfied. Although topamax has been helpful more than once for me, they don’t call this stuff "dopamax" for nothing. I’m extremely tired at inappropriate times, I cannot wake up in the day time without feeling dizzy and exhausted. If you have a schedule that requires you to be awake and aware for a good amount of the day I would avoid taking this stuff. This med is royally screwing up my ability to get to my morning classes. Other symptoms I feel were initial cold symptoms, tingling hands and feet, restlessness, and going to the bathroom more than usual"

8 / 10
Was this helpful?YesNo
50 Report

Are you taking this medicine?

  • Karla...
  • Taken for less than 1 month
  • July 4, 2016

"I am a 56 y.o. woman. I need to loose 20%bw. ( about 36lbs) I tried Contrave with horrible side effects. Dr prescribed Topiramate because of migraines. I have been taking 25g a.m.& p.m. I bike 3x and wk. No migraines, some minor "word salad" steady small weight loss. 6lbs in 3-4 weeks. Decreased appetite and increase in drinking water. It has been so easy, I'm surprised when the scale is down!! I am extremely happy so far."

9 / 10
Was this helpful?YesNo
73 Report
  • Bella...
  • December 31, 2015

"I suffer from depression, bipolar, and anxiety and believe me it is a struggle. I always had a perfect 10 body weighing at 112 now 175 at 5'2 then I was put on Abilify to add to my other meds. My doctor weaned me off the abilify and put me on Topomax for mood swings and to loose weight. I am on 50mg at night. Within 2 weeks if I don't see a change she will bump my dosage up. I am praying that it works for me. The struggle is real and I feel for everybody going through this pain. I want to wish everyone good luck and a happy new year! I will keep you all posted"

Was this helpful?YesNo
76 Report

More FAQ

  • Banml
  • Taken for less than 1 month
  • November 27, 2015

"I just started 25 mg on 24th, 3 days ago. I knew something was strange on Thanksgiving; I didn't go back for seconds, normally I go for thirds. I had no idea the medicine was working that fast. Well, today, I really knew it was working. I went into town about 1:00, and I hadn't eaten anything, so I stopped and got a dollar burger and fries. Well, it was all I could do to finish it. I have never not been able to finish anything; seriously, I love food. But recently, my doctor put me on this because I have an eating disorder that has caused me to gain weight, and I've never had a weight problem, and it's really upsetting me. I was afraid to get my hopes up, so when I got home, I tried to eat something that I loved but didn't even want it at all! It's unreal!"

9 / 10
Was this helpful?YesNo
76 Report
  • ZFera
  • Taken for 1 to 2 years
  • February 14, 2024

"I've been on Topamax for 2 years! I've had my struggles at first with weight because of being on medications like Hydroxyzine, Buspar, Lamictal. I could never lose weight because they were massive weight gain medications. I figured that out maybe years later! And the higher doses of Effexor XR, considering I was diagnosed with the higher end of the autism spectrum with ADHD, GAD, Acute Phobias, PTSD, etc... Well, long story short, I stopped taking Lamictal in 2021. I had been on it since 2015, so it was a 2-year wipeout. By 2023, I lowered my antidepressant dose of Effexor XR from 150 to 37.5 by tapering. I tapered off the Buspar as well. My life did a complete 180. Being a 30-year-old male at the time, weighing 278 pounds in January 2023, as soon as I eliminated most of those medications, it was only half the battle. I stayed on Topamax at 50mg twice a day with Effexor XR at 37.5mg. I started to drop weight and now, at 31 years old, I'm 155 pounds. I hope this helps."

10 / 10
Was this helpful?YesNo
8 Report
  • Rita
  • Taken for less than 1 month
  • March 22, 2016

"I've struggled with the weight roller coaster since pre teen. I was prescribed topamax 3 months ago but quit within 3 days because I didn't feel different and my appetite was unchanged. Last week I ran into a friend who has was significantly over weight and suffered from depression. She has lost 50 lbs in past year while taking topomax. So, needless to say I've started taking 25 mg in morning and 25 mg at night. Tomorrow I'll increase to 50 mg at night. It's only been a week but I haven't had any side effects."

Was this helpful?YesNo
72 Report
  • lilyb...
  • April 27, 2017

"I started Topiramate on March 30 th also alone with Phentermine 15 mg I was not convinced even though all the results I had read were good. I'm 27 days into the diet an I've lost 14 lbs. I weighed 169 anx now down to 155lb I need to lose at least 25 more. I have deteriorated disk and extra weight really makes a difference in your back. I use to weigh 125lb over the years I've gotten to were I can't do very much walking or exercise I'm so thankful my Dr put me on this I can't believe it the Topiramate at nite what really made the difference I was up and down during the nite eating now I eat jello and a little whipping cream that's it. I don't get hungry during day but I do eat. I did have some side effects but after about 5 to 7 days they went away. It Works Thanks"

10 / 10
Was this helpful?YesNo
64 Report
  • Nelli...
  • March 29, 2017

"It takes a while to kick in, and you HAVE to gradually increase your dosage - like, start at 25mg twice a day, then every 2 weeks, 25 mg more - gradually increase to the max dosage your doc wants you on. Otherwise the more negative side effects will be more pronounced. I am on this medication for migraines, and the weight loss is a "side effect." It took about 6 months before I saw any weight loss at all, so I was frustrated at first, though the migraines did start to subside a bit. Now, I've been on it a year, and I've gone from 235 lbs. to 205 lbs. without trying at all. Like, I'm not exercising any more than I was, I haven't been dieting at all that I'm aware of - I just don't crave food like I used to. Headaches better too."

9 / 10
Was this helpful?YesNo
64 Report
  • 2Bles...
  • July 1, 2017

"I started taken one 25mg topiramate two days ago, Wednesday June 28th, with one 37.5 mg of phentermine tablet, 1/x daily. June 28th Starting weight 225.1 on Friday June 30th, which was 2 days later, I'm 217lbs I've dropped 8.1 lbs in 2 day. OMG! I'm praying this continues to work out for me because I need/want to lose 58+lbs. I've really struggled with my weight for the past 7 years, On and off different diets, going to gym, personal trainer etc... my doctor wants my body to stay in ketosis. I know I can do this!"

10 / 10
Was this helpful?YesNo
62 Report
  • Midge
  • January 19, 2020

Topamax (topiramate) "I was put on Lyrica and Gabapentin after I went through a bout with Ovarian cancer. I ended up with severe neuropathy in hands and feet. Anyway... also going back to 1994 I injured my back at work and at the time I weighed 98 lbs. I am only 5 ft. tall. So I see a pain dr. every month for pain. The first meds I mentioned famously add a lot of weight to your body which I did not know. I gained 40 lbs. which I have not been able to remove from my body until maybe now. My wonderful pain dr. has prescribed topiramate for me and we will see what happens. Maybe less pain and a nicer body."

Was this helpful?YesNo
44 Report
  • Anonymous
  • July 31, 2019

"I took Topamax to lose weight after being on Pristiq and it did help me lose weight fast...however, the cost was great. It worked for weight loss and helped me with panic attacks and sleep. However, it gave me the worst depression of my life. I have not known despair the way that I did while taking this drug. I could not bring myself to get out of bed to live my life. I lost my job, I cried all the time, and did not care about anything. And to add to this, I developed severe respiratory issues. I would be hacking up a lung and my chest would be killing me 24/7 from coughing and I couldn't talk because it was so bad. Bad enough that I went to the ER worrying that I had pneumonia twice and we concluded that it was a side effect of the drug. Sure enough as soon as I stopped taking it it went away and I began to get my life back. It also didn't help for my seizures. I actually had more seizures on this med than I did prior to taking it."

2 / 10
Was this helpful?YesNo
47 Report
  • R88ster
  • Taken for 5 to 10 years
  • May 26, 2019

"I began using this medication in 2005 after major traumatic brain injury, and also migraine. After a bit I noticed it helped me get rid of the baby weight after each of my first two babies then I was quite chunky and a major back surgery...gaining way too much. I'm 5'2 at like 200lb . Ugh. So I'm up to 100 mg per day to help me lose weight. It makes me groggy so I'm a bad patient and take at night. My Dr would like me to increase to 200mg per day and take during the day... curious how you all spilt the dose each day, during the day? I need to get this weight off so I don't ruin what the back surgeon did to help!!!"

8 / 10
Was this helpful?YesNo
47 Report
  • Desti...
  • Taken for less than 1 month
  • August 24, 2016

"I started againTopomax about 1& 1/2 week ago for migraines and I am down about 8 lbs. I am overweight due to the fact that I just had my last child and I did eat what I wanted to. I did work out before, during, and now after my pregnancy. Topomax has reduced my cravings I absolutely love sweets & southern foods(I'm from the South:) I did occasionally soda but I did regularly drink Izzy a healthy carbonated drink but Topomax makes all carbonated drinks tastes horrible which is great if you have issues drinking soda all the time."

8 / 10
Was this helpful?YesNo
65 Report
  • chunk...
  • Taken for less than 1 month
  • July 10, 2017

Topamax (topiramate) "I started this 4 days ago.. taking 1/2 of 50 mg at night.. so 25 mg. I will do that for 7 nights, then up to 50mg for 7 nights, then 75 mg for 7 nights, then 100 mg for 7 nights, and so on until I reach a mg my Dr. and I are comfortable with. So far I have not had any side effects except- not being hungry. In the last 3 days I have hardly eaten anything. I've been very thirsty for water, soda taste like crap- and I was very addicted to diet coke. I haven't weighed yet... been meaning to. Last I weighed was a month or so ago, and I was at 180 ish. Today is July 10th 2017. I will weigh after work and see where I am so I have a better idea who this will effect me! I've gone from 120 to 180 ish in the past year - with different meds.."

6 / 10
Was this helpful?YesNo
59 Report
  • Anna...
  • March 16, 2019

"I use Topamax 100mg for migraine, mood & the one my psych doctor doesn't know about: weight loss. I didn't lose a pound on this med for years but have been steadily dropping weight since August '18. Of course I'm also counting my calories closely, trying not to exceed 1,300/day. But sometimes I go way past that amount if it's PMS time. There have been no side effects whatsoever. A little numbness/tingling. Topamax is neither stimulating nor sedating for me & doesn't affect my mood at all. My hair is shedding a tad more than before, but Nioxin shampoo slows that down. I do worry about potential long-term side effects or nutrient deficiencies. I've gone from 155 to 124 lbs. on Topamax & my CICO diet. Totally sedentary lifestyle & unhealthy food, lol. It's all about the calories you take in vs. how many you burn each day. A TDEE calculator can help you determine how many you should be eating. Relying on ANY drug to fix you is gonna end in failure. It takes work."

8 / 10
Was this helpful?YesNo
48 Report
  • Sweet...
  • Taken for less than 1 month
  • April 13, 2021

Topamax (topiramate) "I just started topamax so far I get the tingling feeling and the brain fog nothing major though and I zone out a lot. I barely eat and when I do it’s healthy I hope this works I’ve tried everything I’ll update in a month."

8 / 10
Was this helpful?YesNo
33 Report
  • lojola
  • February 8, 2016

"I just started taking this medication today (02.08.16) for weight loss. 25mg in the morning and 25mg in the evening. 3 years ago, I was able to loss 70 pounds on my own but have gained 40 of it back even though I continue working out and eating healthy. I am hoping this will help encourage some weight loss as I am getting married in November 2016. I weighed 195 on the scale at my house this morning.I had yogurt for breakfast and haven't had the urge to eat my banana or apple that are sitting on my desk. That's good, right? Maybe it's a psychological thing? I'll be sure to keep y'all updated."

Was this helpful?YesNo
66 Report
  • Almucha
  • October 11, 2016

"I really hated taking this medicine . At only 25 mg I was feeling like a zombie all day , very dizzy , confused , had a hard time putting sentences together . Very embarrassing I couldn't drive cause I was almost always crashing due to the. Lack of concentration. Also I was always angry . I didn't even want my kids to come near me :( that's when I decided to stop taking it. It really did help me loose weight but I rather loose weight on my own than to have to go through that nightmare again."

1 / 10
Was this helpful?YesNo
62 Report
  • Isnt...
  • Taken for less than 1 month
  • June 5, 2015

Topamax (topiramate) "I started 25 mg on June 2nd at bedtime I had the tingling in my hands and bitter taste in my mouth I also fought to remember what I had done all night and morning I felt like a complete zombie..I took one dose and haven't took anymore since the side effects this pill has isn't worth me risking it I'd rather keep my weight until I find another way to get it off and to this day June 5, 2015 I still have tingling in my hands and feet and numbness in my arms along with swelling in my fingers I will never take another topamax it's awful...."

1 / 10
Was this helpful?YesNo
69 Report
  • chubb...
  • Taken for less than 1 month
  • February 3, 2016

"Update I started Topamax a week ago tomorrow 50mg at night and I have lost 5 lbs I'm 5'3" and started at 157lbs I am at the Dr.s now stepped on the scale and I'm at 152 so I couldn't be happier...I have very minimal side effects taking them at night helps with those I sleep very well and I have had some tingling fingers but nothing unbearable...all in all I am very happy with the 5 lbs lost in 6 days looking forward to more weight loss in one more week I do increase my dosage to 100 mg so we shall see about those side effects...but if things keep going the way then I might stay on them for a while"

10 / 10
Was this helpful?YesNo
65 Report
  • Still...
  • December 30, 2016

Topamax (topiramate) "I did/am experiecing the tingling everyday in my fingers, I am not hungry. I did have the brain fog to where I wouldn't drive. I wouldn't make any decisions about anything without talking it over with someone I trusted first. I am now up to 75 in the morning and at bedtime and I still have the tingling but the fog has been lifted the headaches are SO much less BUT I have only lost 3 pounds. Can't seem to stop smoking even with this. Still hoping this will help with the smoking. Wish me luck"

7 / 10
Was this helpful?YesNo
58 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.