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Imitrex User Reviews & Ratings (Page 3)

Imitrex has an average rating of 7.8 out of 10 from a total of 206 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 14% reported a negative experience.

Reviews for Imitrex

Commonly mentioned side effects
  • Amc...
  • November 16, 2013

For Migraine "Works super fast and well. Gets rid of my migraines fast when I take it with a Motrin 800, BUT... it makes me sweat buckets. I took it at work before my shift, and 2 hours later my migraine was gone, but I had sweated through 2 shirts and was visibly dripping. It was pretty bad. It does it every time I take it, so I try not to use it if I can help it."

7 / 10
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  • Lyn...
  • June 22, 2014

For Cluster Headaches "I have been using Imitrex since it first came out in the '90s. It was a godsend. I've had migraines for 42 years. I get about six migraines a month. Imitrex always works, but for me, I pay a price with stomach aches. Sometimes I refrain from taking Imitrex for fear of the stomach pains."

9 / 10
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  • pho...
  • April 24, 2010

For Cluster Headaches "I have suffered from cluster headaches for over 15 years and have tried almost everything offered by hospitals and over the counter. I recently was given Imitrex in a nasal spray by my doctor, and as long as your nasal passage is clear, I have found that about five to ten minutes after you taste it in your throat, the headaches go away. It is the best medicine I have ever come across for cluster headaches, and my days and nights are much better because of it."

10 / 10
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21 Report

Frequently asked questions

  • hea...
  • November 3, 2014

For Migraine "Great. I've taken it twice and didn't experience any major side effects. Kicked in after 20-30 minutes, was fully ready to go at 60 minutes after. That said, I did experience some side effects including: mild heartburn-like feeling during the first 1-2 hours after taking it, moderate heaviness/tightness in my jaw that lasted just about 12 hours after taking, some drowsiness, some mild neck pain (which could have been the migraine), and a tightness/tingling (very mild) in my forearms. But I'm free and clear of the headache. Definitely plan on taking it again."

9 / 10
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  • Dsi...
  • Taken for 2 to 5 years
  • May 25, 2015

For Cluster Headaches "Imitrex has helped me 100% with my cluster headaches. Certain foods trigger these painful headaches, and even though I know most of the triggers, and even though I try to avoid them, it's impossible to eat and not have at least one or two of these triggers in my food. My doctor tried me on several pain meds for these headaches, but nothing worked. The headaches got so bad I was literally pulling my hair out and was thinking about suicide. Then my doctor gave me Imitrex. As long as I know I have access to Imitrex, I am fine. I finally went to a wonderful neurologist who has been very patient in trying other meds to work with the Imitrex. I do take the generic of Imitrex."

10 / 10
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  • one...
  • December 22, 2015

For Migraine "I have been suffering from migraines since around 16, and now at 36, although they have become less frequent over the years. They are horrible, as I usually am out for the entire day, bedridden in a dark room. I have always been very paranoid to try actual migraine medicine, so I have taken Vicodin for the pain. I recently had a migraine at work and decided to try an Imitrex my doctor prescribed me. I was nervous to try it, but am so happy I did. I waited a few minutes after having the migraine before I took it, but it relieved me of my migraine within 30 minutes. I did experience some effects like muscle stiffness in my neck, tightness in my face, and a burning feeling in my nose and forehead for about an hour, but I'll take that any day over a migraine."

9 / 10
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  • LoH...
  • Taken for 10 years or more
  • October 31, 2016

For Migraine "I have suffered from migraines for many years. Before I started using Imitrex (about 15 years ago), some migraines would affect me for days. I missed out on so much back then. Imitrex changed that. I normally can take one dose and get complete relief in an hour. The only side effect that I have ever suffered is sleepiness, but it's not so severe that I can't take Imitrex while working if a migraine strikes. This medication has been a lifesaver for me and changed my quality of life."

10 / 10
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More FAQ

  • Ele...
  • Taken for 2 to 5 years
  • July 1, 2018

For Migraine "This drug will get rid of my migraine about 70% of the time, but I only use it when nothing else works because the side effects are almost as bad as the migraine itself. It makes my skin feel prickly and tight, and my throat feels tight and like I can't swallow. It gives me such intense nausea that I often don't speak when I take it because I feel like if I open my mouth, I'll throw up. From trial and error, the nausea seems to abate if I take it with food, but if I forget to take it with food I have to force myself to eat through the nausea. My brain also feels really foggy, and basic actions are difficult when I take it. I'm glad there are people who don't react like this, but I am definitely asking to be switched to a different medication."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 1, 2012

For Migraine "This medicine kept the migraine from becoming full-blown. It made me sleepy and out of sorts, but this is better than an agonizing migraine. I took it as soon as I saw the visual effect, and within 30 minutes, my vision was back to normal. However, I still had a mild migraine with very little nausea. Imitrex made me tired, and my body felt heavy. It also made my tongue feel swollen, but it wasn't. But I'd take this over a full-blown migraine any day! It seemed to fast-forward the headache rather than it being debilitating like last time. I still lay around all day though."

7 / 10
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  • Van...
  • September 18, 2015

For Migraine "I have tried this medication in the past, and it did not work for me, but now, after revisiting the drug with years of migraines with no relief, I have found that it works well for me now. I tend to have extreme nausea and vomiting with my severe headaches, so I also use the nasal spray form (depending on how nauseated I am). They both work well if taken early in the migraine. I did, however, have a severe reaction the first 2-3 times taking it (nausea, vomiting, abdominal upset), but I forced myself to take it again. Now my experience is 'head tightening,' which I see can be common with this drug, and after about 15 minutes of this, I feel a 'loosening' and finally relief. I have not experienced any other symptoms with the tablet form."

8 / 10
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  • tri...
  • April 28, 2013

For Cluster Headaches "I've just started taking Imitrex. The first time I took it, I thought I was getting lockjaw. I was quite worried. I took it again the next day, though, because it did take care of my headache. Since the first time I took it, the side effects have been minor. Hopefully, it stays this way."

8 / 10
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  • mer...
  • December 6, 2018

For Migraine "After I had my son, I had horrible migraines, sometimes daily. I tried every over-the-counter medication, including Excedrin, Tylenol, and Ibuprofen. I recently started taking Imitrex. It's amazing. It does take a while to kick in, probably about an hour to two. The pain goes away within about 20 minutes, but I still have a pressure-like feeling until about an hour or two later. It also has really helped my depression, maybe because of the serotonin element in the medication. It doesn't make me tired or dizzy, luckily. I do feel relaxed, but not in a bad way. I really love it."

9 / 10
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  • Anonymous
  • March 13, 2009

For Migraine "God bless Imitrex. I can take the injection either at the start of a migraine or right in the middle of it, and it works like a charm each time. I don't know what I would do without it. My migraines were crippling, but thanks to Imitrex, I have my life back."

10 / 10
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  • Joh...
  • October 24, 2011

For Migraine "I have been a migraine sufferer since 1993. As the years went by, they got worse, where over-the-counter medicines didn't help. In 1996, I was diagnosed with migraines by a neurologist after going through test after test to rule out other medical problems. Believe me, I actually had to ask the doctor, is it possible to cut that piece of brain out? That's how severe they are. He prescribed several different kinds of migraine medicines, and none worked for me until he gave me Imitrex. This is actually a miracle pill. Yes, the side effects are horrible and the migraine gets worse before it gets better, but once it's gone, you are back to your normal life as if you never had an episode. I don't leave home without it."

9 / 10
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  • Mon...
  • Taken for 10 years or more
  • August 30, 2016

For Migraine "I've had migraines since age 12, so 30 years. I received Imitrex at 25 and am forever grateful! I average one migraine every 2-3 months, usually with changes in weather and/or interrupted or reduced sleep. If I recognize the aura phase (usually smells, sometimes halos or light streaks/trails) and take Imitrex within the first couple of hours, it can completely ward off the pain. If I don't catch it in the aura and take it after actual pain hits, it's still helpful, but I will still be subject to 2-3 days of pain and need recurring doses. Plus, I supplement Imitrex with naproxen and caffeine. But it works. I've gone from being bed-bound in a dark, silent room to being able to work-even with fluorescent lights-without vomiting or worse. Life-changing."

9 / 10
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  • Che...
  • Taken for 5 to 10 years
  • July 23, 2020

For Cluster Headaches "I use Imitrex to treat my cluster headaches. I have episodic clusters. Usually get them once a year for a month or more. I get two to three attacks a day during the cycle. I use Imitrex injections and pills, the injections get rid of the pain in about 10 minutes, and the Imitrex pills take about thirty minutes to work. Don’t know what I would do without them."

10 / 10
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  • Rjo...
  • Taken for 1 to 2 years
  • August 6, 2017

For Migraine "When I moved to Indiana, I started getting migraines. My doctor prescribed Imitrex 25 mg, which worked beautifully as long as I took it when the migraine started. Though it still doesn't always work, I take another dose 2 hours after the 1st dose. I developed a tolerance to it and now need to take 50 mg. Fortunately, my migraines have slowed down to a dull roar as I've figured out my triggers. Imitrex has some annoying but mostly tolerable side effects that dissipate with use, such as feeling physically fatigued, feeling kind of drugged, trouble thinking clearly, increased blood pressure/heart rate, sometimes I feel shaky."

8 / 10
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  • Str...
  • June 14, 2016

For Cluster Headaches "I've suffered from cluster headaches since I was 14 years old. I'm 35 now. My last headache was in 2013, shortly after my mother passed. I thought I had outgrown the headaches, but in May of 2016, here I go again, going into my second month of having them every day. I've tried Imitrex, you name it. Sometimes painkillers work, sometimes they don't, but like many other cluster headache sufferers, I've been through hell. I don't know what to do. I'm a truck driver, and it makes it hard to do my job even after the headaches have gone. I just wanted to share my experience."

3 / 10
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  • Anonymous
  • March 18, 2009

For Migraine "Imitrex does the trick of getting rid of my migraine every time, but the side effects are a little rough. I feel as though my neck and chest are tightening and achy, but if I go to sleep about 10 minutes after taking Imitrex. I miss the side effects happening to me, and just wake up feeling better."

7 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • December 10, 2016

For Migraine "I suffered from migraines since I was 10 and am now 38. Mine are triggered by stress and monthly hormone fluctuations. I first tried Imitrex when I was 21, and it made me so dizzy I couldn't stand. Recently, I tried it again when I was having a migraine at work, and it was so bad I went to the emergency room, afraid I was having a stroke. I used to take OTC meds and isolate myself in a dark, quiet room. My migraines kept me from enjoying important events with my children. This drug has been life-changing. I have experienced some sleepiness as a side effect, but nothing that makes me non-functional."

9 / 10
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  • KAW...
  • Taken for 10 years or more
  • June 30, 2022

For Migraine "Suffered terrible migraines since late teens. Started on Imitrex in 2000, over 22 years now, and it is the only medication that has worked. Usually knocks migraine out within an hour, even when it is a severe one. I don’t know how I would cope without it. I’d be stuck in bed for two days before I discovered this miracle pill. I don’t have side effects from it either. It changed my life, truly. I still get migraines constantly, usually in the mornings, but at least I can take a pill and get on with my day."

10 / 10
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  • Mic...
  • Taken for 10 years or more
  • March 29, 2023

For Migraine "I've had one experience with Imitrex. I was living in the Midwest near an AFB hospital (in the mid to late 1990s). My mother and I came down with migraines the same evening. By the third night, we both had tried everything that we had been prescribed, and the migraines were just getting worse, but it was the '90s, and migraine medication besides pain meds was in its infancy. I was in the best condition, so I drove the short distance to the base hospital, and within an hour, we both found ourselves participants in a drug trial for Imitrex with the promise that if it didn't work, we'd get 'something stronger.' Soon, we were both having chest pains and heart palpitations, and I couldn't catch my breath. Why? We both have heart valve issues that we didn't know about. We were on heart monitors for hours afterward, but we did get 'something stronger' to cut the pain. I know people who swear by Imitrex, but please take your first dose at a hospital or doctor's office! It has interactions that can be quite serious."

1 / 10
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  • Lol...
  • Taken for 6 months to 1 year
  • December 7, 2016

For Migraine "I have suffered from migraines for 32 years. Have taken several medications and combinations of said meds prescribed by my physician to combine. This past year has been a mild one as far as migraines for me, but have had around 13, I guess, and we tried Imitrex. I can say that it has worked for me. My migraines are triggered by the changes in barometric pressure due to weather, so I almost always have them in spring and autumn."

9 / 10
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  • Dre...
  • Taken for 5 to 10 years
  • September 6, 2016

For Migraine "Imitrex works well to rid me of my migraines a few hours after I have taken it, but the side effects for me are pretty bad. It makes me feel really weird, and it seems like my whole body is achy and my muscles are burning. Of course, the side effects that I get from this medicine are nothing compared to a full-blown migraine, hence why I've been taking it all these years. I will be talking with my doctor at my next visit, though, about switching medicines because I'm sick of feeling like crap after taking it."

7 / 10
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  • She...
  • March 19, 2012

For Migraine "I have suffered from migraines for 32 years, the older I am, the worse they become. I have both the Imitrex pills and the shots. When I am nauseated, I must use the shot. Approximately 1 minute after injection, the intense burning in my head and the amplified headache are the worst side effects, however, NOTHING compared to the migraine. Usually, the migraine is gone in 15 to 30 minutes, and I sleep it off. There is also the 12 to 24-hour Imitrex hangover from the shot. Muscles feel as though they are made of jelly, an overall wiped-out feeling. The pill does not have the burning effect for me, and it takes the full 30 minutes to combat the migraine. Imitrex is the only medicine that has worked for me consistently over the years. I become immune to all other medicines."

9 / 10
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