Skip to main content

Imitrex for Migraine User Reviews (Page 5)

Imitrex has an average rating of 7.7 out of 10 from a total of 170 reviews for the treatment of Migraine. 67% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Imitrex

  • Anonymous
  • March 27, 2012

"My first experience with Imitrex was taking it at work...well, that was not a good idea! I started to feel the migraine coming on, so I took it at the first symptoms like I was told and went about my day. I'm a technician for an ophthalmologist and I started to get a hot flash. I stood up and my arms and legs went totally numb. Since I'm on Topamax too I expect a little tingle, but this was a RUSH. All this aside, about 30 minutes later most of my heavy duty migraine symptoms were thwarted. Not gone, but a lot better. I feel they would have been much better if I had been able to lie down rather than been on my feet working. I also still had a pretty decent headache and photophobia the rest of the day."

7 / 10
Was this helpful?YesNo
9 Report
  • Nicky...
  • Taken for 10 years or more
  • August 3, 2016

"I have had chronic migraines for as long as I can remember. To the point where I can't even talk to answer questions, walk straight, I have been accused of being drunk or high because if it. They could last up to three days, the first time I tried imitrex.... It was quite literally the Holy grail from then on. The pills take away any aura or migraine in about 20 to 30 minutes and the shots give immediate relief. Wether or not it's a placebo, I swear to the gods, as soon as you inject into your upper thigh your migraine goes down a few pegs. Within a few minutes, nearly or entirely gone. If you have migraines or clusters ask your doctor. Don't take irresponsibly because it can have some weird effects on people."

10 / 10
Was this helpful?YesNo
6 Report
  • Anonymous
  • Taken for 2 to 5 years
  • October 6, 2012

"Imitrex works for me even if I let it get to the really bad headache--hate to take because of the tightness in chest and achy throat afterwards. But-they do the job and I always say later I should have taken it in the beginning."

9 / 10
Was this helpful?YesNo
8 Report

Frequently asked questions

  • KandyP
  • Taken for 1 to 2 years
  • November 21, 2016

"My migraines are mild but can be long lived, some times lasting 2-3wks with nausea and light sensitivity. I used to treat them with just OTC meds but of course as soon as they wore off it came back. While pregnant I was prescribed Fioricet but headache would still come back. Then I finally got Imitrex and it makes the headache NOT come back! I do only take it at night just for the drowsiness, but no other side effects for me, and headache is gone when I wake up!"

10 / 10
Was this helpful?YesNo
6 Report
  • Leam
  • September 5, 2016

"I was diagnosed with severe migraines a little over a year and a half ago. I was prescribed Nortriptyline as an everyday medication and Imitrex as a "needed emergency pain reliever." The Nortriptyline doesn't always work, and since I am a teenager, I am still in school. If I get a migraine in school, I am supposed to take an Imitrex and go straight back to class. Unfortunately for me, the Imitrex makes me extremely drowsy and sometimes delirious, usually forcing me to go home and still live with the pain of migraines for at least another 12 hours, but it can still last for up to 3 days afterwards. Thankfully, the Nortriptyline works 95% of the time, but the Imitrex only works a good 75% of the time, and then I'm still put out of commission."

4 / 10
Was this helpful?YesNo
6 Report

Are you taking this medicine?

  • ford
  • Taken for 2 to 5 years
  • August 27, 2022

"I've had migraines since I was in my teens. I was prescribed the imitrex injections first and they worked fine at first but after a while it didn't seem to work as well and I didn't like the bruises it left. I am now on the imitrex tablets which work great if I take it when I first start to feel the migraine coming on. If you wait until it past no return, then it doesn't seem to work as well. I haven't really had any bad side effects with the tablets."

10 / 10
Was this helpful?YesNo
2 Report
  • ladybug
  • June 25, 2008

"I started using Imitrex about two months ago. It does wonders for me. I take a short nap in a dark, quiet room after taking the medication and this helps a great deal. I have not had any side effects. I love it and recommend it!"

9 / 10
Was this helpful?YesNo
10 Report

More FAQ

  • Anonymous
  • April 14, 2010

"I'm 59 years old, and have experienced migraines since age 5. Imitrex is the best drug I've used. I take 100 mg at the first sign, and it prevents it 80% of the time. If taken after the headache starts, it stops the pain within 1 hour, and much faster if I lay down. Yes, there are mild side effects--drowsiness, sensitivite to hot and cold, but it sure is better than a headache."

9 / 10
Was this helpful?YesNo
9 Report
  • landb...
  • Taken for less than 1 month
  • March 2, 2021

"I took this for the first time nearly 20 years ago and it caused so much pain I passed out and didn't wake up for 18 hours. Last year my doctor prescribed it to me again thinking I may have grown out of it. So a couple of days later I was having a bad migraine and I took it. After just a few minutes my skull started feeling like it was on fire. The pain was so intense I immediately started pacing not knowing what to do. I ended up laying down while my wife brought me ice packs and I eventually passed out just as I did 20 years ago."

1 / 10
Was this helpful?YesNo
3 Report
  • Music...
  • June 22, 2016

"I am 57. For about 10 years I have had occasional episodes of acute headaches to the point of vomiting. Finally got diagnosed with migraine about 8 months ago (for some reason it never crossed my mind despite a family history of it). Was prescribed sumatriptan. Now, when I feel a migraine coming on I take 1/2 or 1 pill, along with naproxen. Headache is gone within 1/2 hour. My life has greatly improved. No side effects at all."

10 / 10
Was this helpful?YesNo
6 Report
  • Haute...
  • Taken for 1 to 6 months
  • April 17, 2013

"This medication for the price worked the best. I was using this along with Topamax as a daily preventative and also started receiving botox injections. I found that after a few months between the botox, the Topamax and the Imitrex, I was able to use less and less each month."

10 / 10
Was this helpful?YesNo
7 Report
  • Anonymous
  • March 29, 2010

"I had a terrible migraine on Friday and went to the doctors office. The gave me a dose of Imitrex and within 15 minutes my headache was gone. It did make me feel nauseated and my cheeks were tingling but it was 100x better than the headache."

10 / 10
Was this helpful?YesNo
8 Report
  • linhub
  • November 13, 2008

"I find Imitrex to be very effective against my migraines as long as I take it at the start of one. The first and second time I took Imitrex, I experienced stomach cramps. The next time I had to take it, I had eaten shortly before and this greatly reduced the cramping. If I'm nauseous I obviously won't be able to eat a full meal, but the cramps do seem to be decreasing each time I take it anyway. The only other side effects I have are a burning sensation in my nose, and a sore throat, which are both tolerable. Imitrex is very expensive, but definitely worth it to me. I can take a tablet, lay down for an hour or two, and then get back up to live life again."

8 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • September 4, 2008

"I love this medicine! Before I would always worry about the next time I was going to get a headache. I couldn't work or play with my son, I hated it. But now if I get one I can just take my imitrex and 30 minutes later its gone like I never had a headache at all! The only thing I dont like is it is pricey, but I will pay because it works very well. Now that I have tried it, I couldn't live without it."

10 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • June 4, 2009

"Works great for me. Can take 1/4 or 1/2 tablet most of time. Have only taken whole tab on rare occasions. Migraine is usually triggered by irregular or lack of sleep or tension, this medicine makes me sleepy. Most times I'm 100% functional within 20 minutes - no side effects."

10 / 10
Was this helpful?YesNo
8 Report
  • Anonymous
  • January 6, 2010

"Imitrex pills worked for me for a few years but then it stopped being as effective and I had to take 2... Then that stopped working so I tried Imitrex statdose (the injections) and they work wonders. They hurt a lot but the pain in my leg after I give it to myself is far less horrible than the migraine pain! I give myself the shot and lie down for about 15 minutes and I'm fine! Maybe a little pain but I feel much better! I'm also on Timolol, Neurontin, and Cymbalta and my migraines have reduced in number and then this helps when I get them. And the shot works after you've had the migraine for a while - you don't have to take it at the first sign to get relief."

10 / 10
Was this helpful?YesNo
7 Report
  • Anonymous
  • October 16, 2012

"At first I suffered through them. This included splitting head pain, nausea, and vomiting. I started using Excedrin after a while which helped if I took it right away. Then that started to not work so well anymore. I had one really bad one that lasted hours. I was still throwing up at 9 pm and I was now throwing up blood. I went to the ER and when I finally got in they put me on an IV to hydrate me. They then added Imitrex to the bag and I soon started feeling side effects. My head felt like I was going to pass out. My breathing became labored and it felt like someone was sitting on my chest. They said that meant it was working. After about two minutes everything was gone. I got pills to take at home and they worked okay. Not as fast."

8 / 10
Was this helpful?YesNo
6 Report
  • Lisa...
  • Taken for 10 years or more
  • January 8, 2022

"I’ve had migraines since my 20’s- I’m 63 now! Imitrex has been a lifesaver for me. I take 100mg at the onset of migraine. Don’t wait until it’s full blown! I also use Imitrex injection in emergencies. Like waking up with a #10 migraine and I don’t want to wait at least an hour for relief. I’m terrified of needles, but the quick relief is worth it. Plus, it’s an auto-injector, you never see the needle- just press the button. I do notice I feel more side effects than with the pill. Rebound headaches are very possible if you take it too often. I would have missed out on so much life without it."

9 / 10
Was this helpful?YesNo
2 Report
  • lizzi...
  • March 2, 2011

"I'm 54 years old and have used Imitrex for almost 20 years. No side effects except leg pain for about 24 hours, as if I overused in a workout. Was on 100 mg tabs for a long time, with 3 mg self-injections as necessary. Now just taking 50 mg as I get fewer and less intense headaches now. This medicine is worth trying, but ask for EKG first if the doctor doesn't order it, this can help check for heart okay first."

10 / 10
Was this helpful?YesNo
6 Report
  • Manas...
  • March 21, 2017

"Just took it for the first time today , use to use Maxalt. This drug completely knocked me out - so sleepy and tired not to mention feeling very weird. It's been 7 hours and I feel not great . Headache gone but left with fatigue and dizziness. Back to maxalt ."

6 / 10
Was this helpful?YesNo
4 Report
  • MacGy...
  • Taken for 5 to 10 years
  • June 11, 2017

"I have had great success with treating my migraines with this medication with in 5 min of the injection or 10 to 20 min with the pill I can feel my headaches tension and the aura and nausea symptoms subside. For those who take pain meds or a severe bleeding disorder caused by defective gene in the liver ask your doctor if this could be what's happening in your blood stream and central nervous system from pain pills. This is not intended to treat or be a diagnosis or cure for anyone's DIESEASE it's only intended to ask your doctor about to see if it could reduce your headache problems this comes from a patient who is 37 years old with a severe blood clotting disorder and suffers from pain and narcotic pain killer induced rebound HEADACHES"

Was this helpful?YesNo
4 Report
  • Perim...
  • Taken for 6 months to 1 year
  • August 15, 2021

"Like several was confused for a while thinking migraines were sinus or ear infections, first sign is ear pain for me. Have gotten worse as I hit 50 and entering perimenopause. Really struggled with 48 hour long pain vomiting till OB prescribed Imitrex. Like others if I wait too long it’s benefit isn’t as great as when I take it at the first sign. I don’t know about the rebound headaches as my migraines are so bad my headaches for days later and am foggy for a few days. Imitrex maybe makes me a little spacey, but far more functional than with a migraine!! And the side effects are shorter than when I have a migraine."

9 / 10
Was this helpful?YesNo
2 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 30, 2012

"Imitrex is the best medication for migraines I have taken so far. When I first started using it I would get the loopy feeling and slight dizziness. Normal right? But after a month or two and a few more uses of this medication, I started get a burning sensation in my head, behind my eyes and progressively got worse with each time I took it. The side effects have gotten so bad that now I get cold/hot sweats, the burning sensation in my head, and vomiting. I have now switched to a medication that is the prescription strength of Motrin which works just as well."

6 / 10
Was this helpful?YesNo
5 Report
  • Heiny
  • June 4, 2016

"Imitrex has been a life saver for me. As soon as I feel the headache coming I can take half of a 100mg imitrex and in 20 min the headache subsides. I have absolutely no side effects from this medication."

10 / 10
Was this helpful?YesNo
4 Report
  • Anonymous
  • December 23, 2009

"Imitrex is a wonderful medication! I have had hormone-related migraines for a few years now, and while NSAIDs would shorten them, they wouldn't eliminate them completely. I only had to take a 25 mg Imitrex pill and rest for a little bit, and my headache was gone within an hour or so! The only side effects I may have experienced were a slight ache around my forehead and jaw as the headache was fading and a little bit of feeling "out there", though these feelings could have been due to the migraine itself. Overall, I would highly recommend this medication and am very grateful to its makers!"

10 / 10
Was this helpful?YesNo
6 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Migraine

Care guides

Symptoms and treatments

Medicine.com guides (external)