Sulfasalazine for Crohn's Disease User Reviews

• thw...
• Taken for 1 to 6 months
• October 30, 2019

"Diagnosed with Crohn's over a year ago and was in pain daily. Still waiting on insurance to cover gastro and surgery. In the meantime, my PCP offered up sulfasalazine, and I agreed to try it. It's the first time I've been symptom-free in years. I barely have any bloating or pain anymore, and I have almost normal bowel movements again. I did feel an attack coming on, so he added prednisone for two weeks, and everything calmed back down. As long as I'm taking this and not eating too many processed foods or heavy meats, I'm good. As far as I'm concerned, this drug has been a miracle for me."

• Anonymous
• Taken for 6 months to 1 year
• July 13, 2014

"Severe flare put me in the hospital. Have had no problems in 9 months of taking sulfasalazine, went against doctor's advice, chose this over stronger medication. All labs have been good since. Also got a new doctor!"

• eri...
• May 24, 2013

"I tried Lialda, Pentasa, and a few other medicines for my moderate Crohn's disease, and they all made it worse. I tried sulfasalazine, and I am symptom-free as long as I don't forget to take any doses. If I miss a dosage, I may have some loose stool, but after I go back to taking it, I once again am symptom-free."

• Mik...
• February 1, 2017

"My doc said, 'let's try sulfasalazine.' So we did, and I've been on 1000mg three times a day. Don't even realize I have Crohn's disease most of the time. (Recommended). There is that other part where everyone gets a different reaction though..... ."

• lje...
• February 1, 2016

"I've only been taking this for 2 1/2 weeks, but I'm very impressed that my chronic loose stools have completely stopped! I've noticed no negative side effects, and if mild constipation is a side effect, I welcome it. I am now taking a little less loperamide, and I'll be experimenting to see if increasing dosages of sulfasalazine will enable me to take even less loperamide. Later, I'll get blood tests to make sure the new drug isn't having negative effects that I don't notice. After all these years dealing with diarrhea, I'm so grateful my doc suggested I try this stuff!"

• Mag...
• February 5, 2018

"I took this drug every single day for 20 years and had no problems or side effects at all. I cannot get any doctor to prescribe it because they say it is too dangerous. I say they make no money, so they want you to do the IVs that cost a fortune if you do not have insurance."

• rda...
• Taken for 6 months to 1 year
• July 22, 2020

"Came down with Crohn's disease a year ago. Dr. put me on mesalamine at $400.00 a month. Told her I needed a cheaper med. Put me on sulfasalazine at 3000 mg a day, but only $16.00 a month. Works just as well, if not better, than mesalamine."

• Amr...
• March 25, 2017

"Have been on several medications over the years. This being one of them. Was taken off about 9 years ago. Went to many others over the next 6 years. Was put on Lialda 2 years ago with worsening symptoms. More pain and a distended belly. Went to the emergency room for the 4th time in three months. Asked my doctor about putting me back on this. I shouldn't be having this many issues. It's been 2 days on sulfasalazine, cypro, flagyl, and zofran. Stomach is half its size. Way less pain and eating chicken and stars soup. Yeah."

• Cro...
• Taken for 6 months to 1 year
• June 17, 2018

"I was getting gastric blockages quite often that caused a lot of pain and put me in the hospital on more than one occasion. I wasn’t diagnosed with Crohn's until after my surgery. After surgery, my GI doctor gave me a couple of prescriptions for medicine that wasn’t covered under my insurance and I could not afford. We settled on sulfasalazine. I have been taking this stuff for 8 months now. I go to the restroom now more than ever. I noticed that if I would miss a dose or two, I didn’t have to use the restroom so much. This medicine caused bloating, strange noises in my abdomen, constant diarrhea, and abdominal pain. I recently took myself off the drug and feel my best since surgery. I’m waiting for my next appointment with my GI doctor to discuss other medicine or no medicine at all."

• Anonymous
• Taken for 6 months to 1 year
• October 9, 2022

"Diagnosed with Crohn's disease 11 months ago. Was on budesonide, then taper off and put on sulfasalazine 6 pills daily, 3000 mg total. Sulfasalazine worsened knee-down pain in both legs. Also experienced brain fog, anxiety, and depression. Have been off meds for 3 weeks now and feel clear-headed, happier, no depression, leg pain seems so much better. Do have insomnia now. Stopped medicine as new doctor feels I was misdiagnosed. Will find out later this week."

• Lic...
• Taken for 2 to 5 years
• November 5, 2023

"Sulfasalazine is a fantastic medication (for me). I've been taking it for 3 years and it hasn't stopped working at all. Aside from dark urine, I've never noticed any side effects from it. My only real complaint is that the pills are massive, horse-sized tablets. They don't taste bad to chew, thankfully. With just a biologic med alone, I was still getting a lot of joint pain, but adding the sulfasalazine prevents the vast majority of the pain I was experiencing. If I stop taking it, I feel like I'm 90 years old within 2 days because my joints get so bad without it, so it's definitely working. It'd be nice if it helped with my Crohn's more (regarding inflammation and GI health), but fixing my joint pain is huge regardless of that because most biologics I've ever taken never seem to help my joints. I wish I started taking it sooner."

• Luv...
• Taken for 5 to 10 years
• December 12, 2023

"I've been on six 500 mg pills for my Crohn's for 7 years. Aside from a few bad flare-ups, I have felt good on this medicine. I now have anemia (not sure if from Crohn's or the meds) and am having a 3-month-long flare, so the doctor may have me come off of it. Sad to give it up since I haven't really had any side effects. I would definitely try this medicine if your doctor suggests it."

• Luv...
• Taken for 2 to 5 years
• December 24, 2021

"I don’t want to jinx anything, but... Taken for years for Crohn's and helps me so much. Also helps my Crohn's arthritis. Hope it works for me for years to come."

• blu...
• Taken for 1 to 6 months
• June 7, 2018

"Sulfasalazine made me have to go to the bathroom every couple of hours. Felt even more bloated than before."

• One...
• Taken for 10 years or more
• November 20, 2023

"I have been taking this for at least 20 years and have had no ill effects."