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Sulfamethoxazole / trimethoprim for Sinusitis User Reviews (Page 2)

Brand names: Bactrim, Bactrim DS, Septra, Co-trimoxazole, SMZ-TMP DS, Septra DS, Bactrim Pediatric, Bactrim IV, Bethaprim Sulfatrim Pediatric Bethaprim Pediatric …show all brand names

Sulfamethoxazole / trimethoprim has an average rating of 5.1 out of 10 from a total of 67 reviews for the treatment of Sinusitis. 39% of reviewers reported a positive experience, while 45% reported a negative experience.

Reviews for Sulfamethoxazole / trimethoprim

  • Cyneb...
  • March 23, 2017

Bactrim (sulfamethoxazole / trimethoprim) "I've been plagued with UTI's my entire adult life and Bactrim was my go to drug. I got a sinus infection 2 weeks ago and Dr said take Bactrim. My tongue swelled up and sores developed on it, that was AWFUL! I've never had any reaction before. I'm really disappointed because it's always been my go to."

5 / 10
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  • MShel...
  • October 4, 2015

Bactrim DS (sulfamethoxazole / trimethoprim) "I suffer from frequent severe migraines and disclosed this info to the physician during my visit. Recent sinus infections I took a Z-pack and was done but this time was my first time taking Bactrim - DS. Painful headaches, stomach aches, constipation even after drinking water frequently daily. Hoping I don't get the yeast infection or any other issues some patients complain about."

5 / 10
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11 Report
  • Feeli...
  • Taken for 1 to 6 months
  • June 17, 2020

"Bactrim seems to be the only antibiotic that works for me. If I get a sinus infection, Bactrim works wonders. I don’t have side effects, except loss of appetite sometimes. I am now using it as a preventative medicine due to allergies. With everything shut down due to COVID-19, I could not get my allergy shots. This medicine has kept me from getting sick"

10 / 10
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6 Report

Frequently asked questions

  • Jc...
  • August 9, 2017

"I have a very stubborn sinus infection. I have had 2 rounds of a z-pac, biaxin xl, Augmentin, and no success whatsoever. I'm currently on day 3 of Bactrim DS, and I'm also taking a probiotic, as well as a b complex vitamin with vit. c. in this short time, I am feeling so much better. No side effects at all, not one complaint. I am so happy to be on this, it's actually working for me!!!"

10 / 10
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8 Report
  • Anonymous
  • Taken for less than 1 month
  • December 13, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) "I had been on Bactrim 800/160 mg. 2 x's a day sinus infection included smelling something burnt everywhere I went it was the same smell plus ears felt congested and I couldn't hear well,e yes were watering glands in neck were swelled started healing in 2 days, but cramping started so went to E.R. They admitted me overnight with IV fluids helped some but not a whole lot, then was changed to clindamyacin. In a few days I smelt the burnt smell coming back as well as the ear congestion and cramping never really subsided. I called pharmacy got reacted magnesium for cramping it helped and that night and slept like a log so I thought I would try and start the bactrim again. Well I took it before I went to bed the next day I felt cramping coming back again so I took 2 magnesium read that it has to be 4 hours apart to take meds after magnesium while Im waiting for for magnesium to work cramping didn't seem to wanna subside now I have to go back to doctor and explain all this"

6 / 10
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Are you taking this medicine?

  • Rachi...
  • Taken for less than 1 month
  • December 9, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) "I was given Bactrim DS for an ear and sinus infection. I had never been given this antibiotic, but have also never had issues with any antibiotic, so I didn’t have any concerns. I ate dinner then immediately took my first pill. Within 2 hours of taking it I could visibly see the bloating in my stomach with some mild stomach discomfort. 2 hours after that the severe nausea sat in. The nausea was HORRIBLE!! Then the diarrhea started, which was awful. I did throw up one time, but I think that was induced by drinking too much water. I was afraid I was going to dehydrate. I also experience terrible heart palpitations & weakness. The terrible side effects only lasted about 6hrs. I’m a little over 24 hrs from all this & I feel much better, but stomach still isn’t right & just have an overall feeling of weakness. The dr told me to immediately stop the antibiotic, which was the only option for me. She said it sounded like I had a sulphate intolerance."

1 / 10
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  • MommyM
  • Taken for less than 1 month
  • December 26, 2018

Bactrim DS (sulfamethoxazole / trimethoprim) "I literally took 3 pills and had to stop. I was worried it was a stomach virus but nope it was Bactrim. I’m not sensitive to antibiotics but this was horrible. I threw up and felt nauseous about 12 hours after the third pill."

1 / 10
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6 Report
  • quick...
  • Taken for less than 1 month
  • April 16, 2015

Bactrim (sulfamethoxazole / trimethoprim) "At first, I found myself with more energy and simply lost my appetite, which didn't bother me. Then, the second day, I suffered nausea and vomiting. I discontinued the medicine on the second day, but the nausea and vomiting continue."

2 / 10
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8 Report
  • Anonymous
  • November 7, 2011

"I currently have an inner ear blockage from blowing my nose too hard. I have been on Sulfamethoxazole for 5 days. Still have the blockage and mucky junk in my nose. Doesn't seem to have done anything so far. "

1 / 10
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10 Report
  • jpxj
  • Taken for less than 1 month
  • March 3, 2017

Bactrim DS (sulfamethoxazole / trimethoprim) "I was recently prescribed Bactrim DS for my chronic sinusitis by my ENT. I informed her that I had been prescribed Bactrim in the past, although I did not inform her that it was lesser strength of the two and after eight and a half days of taking two a day I finally had to stop due to the side effects that were occurring. I took the first dosage and felt fatigued and slightly itchy. I reminded myself tho that when I am overtired and restless that I tend to feel itchy so I took a shower and and slept for a while and I was fine. The following few days I had no problems besides light bloating and fatigue. I kept taking my medication as prescribed and after the fifth day I was having radiating pain around the left and right side of my sternum"

4 / 10
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  • Sunny...
  • Taken for less than 1 month
  • June 11, 2018

"Very surprised at the negative reviews. I haven't used in years but about to for persistent sinusitis. I've always found it effective with no side effects, and never caused a vaginal yeast infection as many other drugs have. My guess is those reporting bad side effects are intolerant of sulfa... I'm not but my ex was/is."

9 / 10
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5 Report
  • tony
  • Taken for less than 1 month
  • December 19, 2020

"40 minutes after taking 1 pill my penis began to feel very warm and the skin around the head of my penis was swelling. I called the the doctor and they said probably a fixed drug eruption. The skin around my penis swelled so bad and hurt bad and then in the morning was even worse and all the skin was peeling... My entire pubic area was sore and red. I went to the ER and the doctor there thought it also caused balantis. They did give me another kind of antibiotic but this stuff did a number on me. Also that night I took the 1 pill I felt overall like I had the flu coming on. It was horrible. I am only 3 days out from taking 1 pill and my penis swelling is a lot better but where the skin came off is really tender yet. I will never take this pill again."

1 / 10
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3 Report
  • LedZe...
  • January 8, 2017

"My first time on this medication, so far I'm not impressed. I'm on day 3 right now for a sinus infection and I still feel basically the same as I did the day I went in to see the dr, only my throat is incredibly MORE sore and I'm coughing when I wasn't before. Having trouble sleeping and I have no appetite. Hopefully I will see some improvement in the next day or two."

3 / 10
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  • Cine
  • Taken for 1 to 6 months
  • June 5, 2017

Bactrim DS (sulfamethoxazole / trimethoprim) "I recently took Bactrim for a sinus infection. My first day of taking the bactrim. I got nervous and my hands started to itch I couldn't sit still. I broke out in a red rash on shoulder and left hand and my feet is red and both sides. But I had previously took bactrim before over the years with no problems. And this time I was shocked because I had taken it before. So I went to the Urgent Care and they told me not to take it any more. So I am throwing the cheap in the trash. And I just hope that my sinus will heal on its own."

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  • Bill
  • Taken for less than 1 month
  • October 5, 2021

Bactrim (sulfamethoxazole / trimethoprim) "Had severe sinus infections every six weeks X 3 episodes, treated with Augmentin 1,000/62.5 2X/D. With fourth infection, Doctor ordered a Culture & Sensitivity & a WBC. I suffered for 5 more days until lab returned data of positive for Serratia Mercescens, with sensitivity to Bactrim. WBC was normal (?). First Bactrim tab 800/160 and felt so much better. Next AM felt almost cured with clear nasal discharge and increased energy even before second dose taken. Way to go C & S!"

10 / 10
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  • Deb
  • Taken for less than 1 month
  • November 4, 2019

Bactrim DS (sulfamethoxazole / trimethoprim) "A lot of people mentioning vomiting and nausea. Be aware that you cannot drink ANY alcohol while on Bactrim. It can make you vomit or cause nausea. It’s very effective for certain UTIs depending on the strain of bacteria. Told this by my pharmacist and doctor. Unsure about sinus but I’m trying that now."

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  • Gabbyjr
  • Taken for less than 1 month
  • July 28, 2015

"I was prescribed this medication for a sinus/ear infection. Within a few days of taking it I could finally breathe and begin to hear again. But I had also developed severe nausea, migraines, and loss of appetite. I have also suffered bouts of extreme fatigue and dizziness that have led to me nearly passing out. And on top of all that I broke out in an awful red, itchy rash all over my chest, neck, and face. This medication is terrible. I have never reacted to anything this way."

1 / 10
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  • ZeeGee
  • June 1, 2017

Bactrim DS (sulfamethoxazole / trimethoprim) "It did help the sinusitis. The side effects were awful. Yeast infection that took 6 pills of diflucan to get rid of. I had blisters.. most about 2" to 3" in circumference on my legs thighs and back. It took a while for them to heal too. My joints ached. Definitely on my never to take again list."

2 / 10
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  • Ali
  • Taken for less than 1 month
  • June 22, 2018

"I feel like I am going insane. I want to crawl out of my skin. I feel restless all over inside of my body. I am stopping this now. It's giving me panic attacks and my heart keeps pounding through my chest. I'm scared I will end up in the hospital. I can't stop twitching and drinking tons of water."

1 / 10
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3 Report
  • Shian
  • Taken for less than 1 month
  • January 23, 2017

Septra DS (sulfamethoxazole / trimethoprim) "I was diagnosed with a sinus infection and prescribed Septa. Instructions stated to take the medication for 14 days. On the 12th day, I noticed a rash on my ankle. By that evening I was running fever. At 3:30 am I woke up with blood on my face - my lips had swollen so much that they had split. My eyes, feet, hands, gums and roof of my mouth were also swollen. My temperature went to 105 and I was hospitalized. The diagnosis was that I am allergic to sulfa drugs. I was in hospital for a week and it took me over six weeks before I was near normal."

1 / 10
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  • Very...
  • Taken for less than 1 month
  • May 2, 2022

Bactrim (sulfamethoxazole / trimethoprim) "Been on Bactrim for a sinus infection, technically for 3.5 almost 4 days and I am still just as miserable as I was when I started. My cough has cleared but the nasal congestion WILL NOT let up it still feels like there is cement in my nose and I have a sore on my nose from having to use nasal strips so much. I wake up everyday hoping it has done it's job but... nothing. So stuffy and miserable. I wish I had been given a z-pack instead. Sigh... if only I wasn't allergic to penicillin."

3 / 10
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  • Trish
  • Taken for less than 1 month
  • January 16, 2019

"The first 1 I took I could tell a small change as if were starting to work already so naturally I took my 2nd pill last night. I had muscle twitching and couldn't sleep due to light anxiety waves I kept having. I had a feeling, but didn't pay attention to my gut that it was the culprit. I paid dearly for it this morning as my anxiety level was like I've never had before. Brain felt fried and very jittery!"

2 / 10
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  • Metro...
  • March 10, 2021

"Dr. prescribed for sinus infection in lieu of augmentin which I can't tolerate. Tried it for 1 day. Took 2 pills and felt very tired and lethargic. Pressure on sinuses is worse. Calling my Dr in the a.m. for amoxcillin prescription which I should have asked for in first place."

1 / 10
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  • Chris...
  • February 25, 2016

"I had a sinus infection 20 years ago that spread to my left eye & left frontal lobe of my brain. I had surgery on my sinuses, left eye, and my left temporal lobe of my brain removed and now have a plastic plate on the left side of my head. So I have frequent sinus infections and headaches. I was given generic Bactrim from the VA. I have taken it 2 days and my sinuses have cleared up any.So I am still having headaches but now have nausea, and diarrhea and stomach pains. I just hope it gets rid of the infection."

7 / 10
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  • Lucas
  • Taken for less than 1 month
  • April 3, 2023

Bactrim (sulfamethoxazole / trimethoprim) "I was put on Bactrim for 10 days and ended up at ER. I have terrible headaches, I passed out, dizziness, so weak I could barely get up. Thought I was going to die before the doctor figured out that I was reacting to the medication."

2 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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