Siponimod User Reviews & Ratings

• Too...
• Taken for 1 to 6 months
• January 22, 2023

Siponimod for Multiple Sclerosis "While I was on Mayzent, I started experiencing blurred vision, jerking, stuttering, and frequent falls. My MS was getting worse, not better. My quadriceps in my left leg have stopped working, and I cannot lift my leg more than an inch off of the floor. My left foot drags when I walk, and now I have to use a bench to get in and out of the shower. I have had several incidents since I started taking this drug. I cannot walk without a cane because my dragging foot causes me to fall flat on my face. I have had to have a spinal fusion due to the falls causing me to have pinched nerves. I have now been put on Ocrevus twice a year infusion, and I no longer suffer from stuttering, jerking, double vision, or falls, however, most of my damage cannot be corrected. I wish I had never used this drug for my treatment of Secondary Progressive Multiple Sclerosis. Completely devastated."

• Xed...
• Taken for 6 months to 1 year
• May 12, 2023

Siponimod for Multiple Sclerosis "I have secondary progressive MS. I was offered this medication as the only available option for me in Canada with SPMS. I was eager to try it. I found my MS got worse. My friends and family members noticed it too. My fatigue, my spasticity, my mobility instantly declined. My doctor wanted me to give it a fair try, as it was the only option for 6 months. I was very vocal it had made me worse. Following that, my doctor took me off."

• Bea...
• Taken for 6 months to 1 year
• October 17, 2021

Siponimod for Multiple Sclerosis "Black Male, Dx Aug 2020. I was on this drug for about 1 year. While on it, I was a mental wreck. Extremely bad brain fog. Physically, I hurt a lot and used a cane from time to time. It didn't work for me, I was a breakthrough case. I averaged 5,000 steps a day while on the drug. Two days off the med, and I was able to walk a mile with no assistance. Now I'm about 4 weeks off, and I've been doing 10,000 step days. (Mind you, just doing house stuff)."

• Anonymous
• Taken for 1 to 2 years
• November 23, 2021

Siponimod for Multiple Sclerosis "I have been on Mayzent for a little over a year now, and I'm pleased with it. I was diagnosed with MS in 2004. My neurologist at the time started me on Copaxone. It worked for me for 15 years. I had no new lesions. Then my insurance company bullied me to switch to the generic version of Copaxone by threatening to not pay for the medication. I was on the generic version for a little over 6 months before I started having new lesions. My neurologist switched me to Mayzent. I was a little skeptical at first reading about the possible side effects. After taking it now for a little over a year, I'd have to say I'm pleased with this medication. I haven't experienced any side effects, nor do I have any new lesions. Thank you, Lord!"

• Mas...
• Taken for 1 to 6 months
• September 16, 2020

Siponimod for Multiple Sclerosis "I have been taking this drug for 6 months. I haven't noticed any side effects. This is delivered to my door each month in a box filled with ice packs because it has to be refrigerated. I also have a Mayzent representative that calls me every month to check on me and to see if anything has changed since the prior month. Overall, I feel it's better and easier than the shot I was having to give myself. I would recommend this."

• Ker...
• Taken for 2 to 5 years
• March 28, 2024

Siponimod for Multiple Sclerosis "I was diagnosed in 1999. I have been on many MS medications, including Novantrone, Avonex, Copaxone, IVIG, steroids, and now Mayzent. I just had MRIs done in 2023, and lo and behold, my lesions are almost nonexistent! They have all but disappeared, and my new neurologist doesn’t feel I even have MS! After 25 years, I’m looking at a possible misdiagnosis or is the Mayzent working? I personally feel the Mayzent is working! So much better than IV infusions and shots you have to do yourself! So grateful I’m on Mayzent!"

• Zen...
• Taken for 1 to 6 months
• May 4, 2023

Siponimod for Multiple Sclerosis "So, it's hot out today, and I'm making my bed, but I'm complaining about the sweat dripping down my face and neck. Then I realized, 'OMG! I'm sweating!' You must understand and excuse my language, but I haven't been able to sweat in ten years. Sure, I'd get burning hot while riding a bike, but I'd only get maybe a drop of sweat on my forehead, feeling like I was going to fall over dead. But I started taking Mayzent three months ago, and I didn't feel like I was going to drop. I just dripped sweat like a normal person! Yeah! Mayzent is my miracle, and I'm still experiencing small changes every day, including sweat!"

• Anonymous
• Taken for 1 to 6 months
• September 23, 2020

Siponimod for Multiple Sclerosis "My experience is I have been using 3 months. No side effects!"

• Dia...
• Taken for less than 1 month
• April 25, 2022

For Multiple Sclerosis "Was nervous about potential side effects, so kept a diary. Nothing to worry about. Finished siponimod today, starting maintenance tomorrow. I will update in 6 weeks. Take care, everyone."