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Sertraline for Depression User Reviews (Page 4)

Brand names: Zoloft

Sertraline has an average rating of 6.9 out of 10 from a total of 1189 reviews for the treatment of Depression. 58% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Sertraline

  • Ruh...
  • July 8, 2017

Zoloft (sertraline) "20-year-old college student. I've had OCD since I was a kid (depression since junior year of high school) but only within the last year did I make the choice to take an SSRI. There's a lot of ambiguity surrounding antidepressants, and you can't really extract much from reviews without feeling reluctant. Yes, there are side effects that appear within the early stages. It is scary to ingest a drug you know little about. However, I can feel happy again, which I thought I had lost the ability to do. I don't believe everything is hopeless, which I truthfully thought I'd feel the rest of my life. It's been a lifesaver, and at 100mg, nothing feels inherently different about myself. It's just a tablet. Don't let it be more than it ought to be."

9 / 10
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  • Kit...
  • June 21, 2017

Zoloft (sertraline) "20-year-old female, prescribed 50 mg for major depressive disorder, social anxiety, and just overall generalized anxiety. Been on 50 mg for 3 months now. Side effects were minor, which consisted of insomnia, loss of appetite, and nausea, though they subsided within the first few weeks and I now experience none. I love Zoloft! I can live again! I'm laughing and going out with friends, not laying in bed all day. I can finally breathe, my surroundings seem so much brighter, I don't harbor hate anymore, I'm me again. More ambitious and creative like I was before I fell into this self-destructive path of depression two years ago. I no longer have the desire to self-medicate with drugs and alcohol. I wish I got on Zoloft a long time ago."

10 / 10
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  • Anonymous
  • August 28, 2020

Zoloft (sertraline) "I refuse to let what happened to me happen to anyone else. I’m an 18-year-old petite female. I began taking 25 mg of Zoloft for anxiety and mild depression. On day 3, I experienced serotonin shock syndrome. I woke up suddenly in the middle of the night with my entire body shaking, my heart rate extremely high, and I was extremely confused. My parents took me to the ER after I told them I felt like my life was ending. The physician's assistant in the ER dismissed me as having a panic attack, even though I’ve had anxiety my entire life and I have never felt close to the way I did that night. My experience left me completely traumatized. I struggled to sleep for months afterward, terrified that I would wake up the same way. PLEASE PLEASE consider what you are putting in your body when you take this drug, especially if you’re a smaller person."

2 / 10
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Frequently asked questions

  • tin...
  • Taken for 2 to 5 years
  • April 14, 2016

Zoloft (sertraline) "My husband has had depression and at times severe anxiety for years. He would have anxiety attacks so bad he was sure he was having a full-blown heart attack every time, and his anxiety prevented him from sleeping because he was sure he would die in his sleep. His depression was bad as well, he was sure the world would be better off without him. He tried different medications but nothing really worked, some seemed to improve things a little bit, but for the most part, I had given up hope that any of them really do much. Then he tried Zoloft. For him, this was the one. It took the edge off after about a week, after two weeks, I could definitely tell a difference. After about 6 weeks, he was back to his normal self."

10 / 10
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  • Gyp...
  • January 25, 2014

Zoloft (sertraline) "I saw my doctor after the anxiety I'd been having the last year hit an all-time high in the last six months. I would wake up wondering 'Why? What am I even here for? What am I working for?' I suffered severe muscle tension in my shoulders and lower back, extreme irritability/mood swings & panic attacks. My heart would be POUNDING as if I'd run a 5k when really I was just lying in bed. It is day two of taking Zoloft... I'm singing (still terribly) to songs again. I feel I have gained the sense of 'normal' that my life has always lacked. I am more clear-headed and find rational thinking easier. My depression and anxiety were destroying my relationships. I'm beginning to see this 'light at the end of the tunnel' people speak of. 50mg a day."

7 / 10
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  • Nic...
  • Taken for 1 to 6 months
  • July 20, 2019

"I had struggled with anxiety for years, and it ended with me feeling very hopeless and depressed. The thought of taking a medication to help me really scared me, but good lord, am I glad I have. I was to the point where I wasn’t taking the steps to help make myself happy, and sertraline (50mg) has helped me bring myself out of the hole and get myself back on track. Please, if you are in the same situation, don’t be afraid to take the chance. I hope to get off of it soon, and I am more than motivated to try and make my life better, not hopeless, and letting everything slip away as I was no more than 2 months ago. It is worth the chance, sending love to everyone who is struggling as I had been."

10 / 10
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  • Mea...
  • November 7, 2019

Zoloft (sertraline) "I’m onto my second box of Zoloft. I took the entire first box over a month at 25mg. I had headaches pretty much every day but they weren’t extreme, just a dull ache. There were also a couple of times where I was feeling nauseous, the pharmacist told me to eat before taking the pill, and that actually helped. So after the first month, I reached my prescribed dose of 50mg daily. No headaches at all now, and no negative side effects at all. My mood is so much better, I actually catch myself laughing at things online or on TV. I am so much more calm and patient with my kids. My husband and I were having huge verbal arguments every couple of days, which I now am capable of refusing to do despite his pushing. I can repeatedly say, 'I’m not going to argue with you,' and stay calm for a long time now, which is obviously new to my husband who is so used to getting a big reaction from me. I honestly feel absolutely fantastic with this medication. Going to ask my doctor about upping my dose for better results!"

9 / 10
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More FAQ

  • Cho...
  • Taken for less than 1 month
  • December 31, 2015

Zoloft (sertraline) "On Zoloft 25 mg/day, and my anxiety attacks have stopped. I haven't woken up depressed (used to wake up depressed and stay in bed) or had suicidal thoughts (had suicidal thoughts almost daily). It's like this medicine has filled in the blanks for me. I don't feel high or euphoric or excited or anything other than what I think normal must feel like. It's quite a change from what I was used to - nonstop anxiety, depression, and I was always thinking about suicide - but all that has stopped and is a thing of the past. I can't even believe I was feeling like that. I now know that something was wrong with my brain, and this medicine has fixed it for me. I am so happy to wake up not feeling sad."

10 / 10
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  • Mey...
  • April 8, 2013

Zoloft (sertraline) "This worked in a way that it got me back on track and made me feel like my old bubbly self. My social skills improved because I love talking to people now. I'm generally happier. Low days are few and far between. Confidence improved and my obsessive thoughts almost ceased completely. Did not experience weight gain. No real side effects reported. This medication helps to get your mind sorted and the rest is up to you to work on yourself."

8 / 10
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  • Joa...
  • Taken for 6 months to 1 year
  • February 29, 2020

Zoloft (sertraline) "Been on this med for about a year. 100 mg is the best dosage for me. Really does help depression, but doesn't take away normal grief. When you're happy, I find that on it, you're really happy and calm, when taking your pills daily and not skipping doses. I found that combining with high-quality magnesium also really helps my mood. The combination is great. Magnesium alone did nothing."

8 / 10
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  • Car...
  • Taken for 1 to 6 months
  • July 27, 2020

"This is the second time I've taken sertraline. The first was for panic attacks when I was 15. It worked wonderfully. The second time is now at almost 22, and I'm back on the 25mg dose. Within two times of taking, I could think clearly, my negative thoughts stopped, my anger almost disappeared. I highly recommend it to anyone who feels like their brain has a million thoughts repeating, this gave me my life back."

10 / 10
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  • Vic...
  • Taken for 1 to 6 months
  • December 22, 2019

Zoloft (sertraline) "This is a very irresponsible website in that you do not instruct the reviewers to state the AMOUNT of Zoloft they take. Without knowing the amount the reviewers are taking, it just amounts to a bunch of worthless babble. It is of no use to anyone."

7 / 10
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  • Cha...
  • August 13, 2009

Zoloft (sertraline) "I started taking Zoloft about 3 1/2 weeks ago. The first week, I started to feel better. Though about 5 days in, I had a really bad hot flash where I had to lay on the floor for about 5 minutes, and then I felt like I was going to throw up. Haven't had that since. I do feel tired so I've started taking it at night. Also, I feel like I have restless leg syndrome. But other than those things, I am now able to focus, and my OCD seems to have calmed down a lot. I still get anxious, but it doesn't stick around as long, and I'm able to move on from it easier. I feel like I can live in the moment and not worry about my past or present or what issue I need to stop before it happens. I am able to focus better at work too. I think my husband likes me now."

8 / 10
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  • Kri...
  • May 5, 2013

Zoloft (sertraline) "My fiancé and I broke up, which made me depressed. Three weeks later, my mother passed away. I couldn't stop crying. A hospital was testing antidepressants on me. We decided that Zoloft worked best for me. It made it easier to cope, and I finally stopped crying. Eventually, I was able to get back to my normal life. I took it for about two months. If it makes you tired, take it before bed, which I did. I believe it saved my life."

10 / 10
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  • Sve...
  • Taken for 1 to 6 months
  • July 13, 2021

Zoloft (sertraline) "Works great for me! I started taking this after my son passed away from suicide. I am on a very low dose (6.25 mg). I had to go to a specialty pharmacy to get this dose. I am very sensitive to medicine. First week: Felt hopeful. Second week: Felt slightly more depressed. Third week: Back to normal. Fourth week: Slight improvement in mood. Fifth/sixth week: Much better. Side effects: None at all. Other coping mechanisms: Eating well, sleeping well, regular exercise, a therapist, a grief support group, a men's group, my dogs, talking about things with friends and family, staying open to my feelings. Overall: I am so happy I am taking this! My story shows that starting on a very low dose (which I don't see a need to increase now) can bring great improvements without any side effects. Hang in there! It does take time but it works great after about a month or so. And, work on your other coping mechanisms as well! Love to all of you!"

10 / 10
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  • Slo...
  • March 17, 2014

Zoloft (sertraline) "After a month of bouncing between morning and night dosing of 150mg pill, I settled on morning. It was making me super sleepy but that went away mostly. Didn't gain but maybe 5 lbs if that (I'm a gym rat somewhat). Felt really stoned the first week or so and sleeping was strange, maybe a little erectile dysfunction at first, but all of that went away too. A month in and the side effects are minimal. The panic is under control, but the depression is completely gone. THANKS A MILLION ZOLOFT."

9 / 10
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  • Eri...
  • Taken for 1 to 6 months
  • August 20, 2012

Zoloft (sertraline) "I have suffered from depression for a long time, but never believed it. I always said 'It's a rough patch, I'll come out of it soon.' Eight years on, I was down and out and suicidal. My doctor recommended Zoloft. I was skeptical and afraid of playing with my emotions. I thought being depressed was just 'me,' but I gave it a go. After 3.5 weeks, the most wonderful thing has happened. I feel normal. I can cope with my day, and I am hopeful about the future. There were side effects for the first week. I took my pill at night, which helped, and kept up the exercise, they passed. If I can give any advice, it's don't be afraid to take control of your body and don't feel guilty if you decide to try medicines. Listen to your doctor. You deserve to be happy."

10 / 10
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  • Lol...
  • September 5, 2019

Zoloft (sertraline) "I put down I have depression, but I also have anxiety and panic attacks and OCD. Everyone is complaining about the nausea. IT GOES AWAY. Moreover, usually after like two days. PLUS this time round, my doctor prescribed me nausea meds for it (I went off it but am going back on because I’m depressed again). Y’all, there is literally medicine that will remove the nausea. And to be honest, for me, it is not that bad as I have IBS as well. Zoloft basically made me chatty, happier, and gave me the inability to cry or feel sad even when I was supposed to be very sad. The inability to feel sad seems pretty good to me. And I was able to feel happy, just not sad. I quit for the sexual side effects. Don’t listen to the people complaining about nausea. I was in bed unable to move for two days from the nausea, and I’m still 10/10 recommending it, so trust me it’s fine."

10 / 10
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  • I...
  • December 7, 2012

Zoloft (sertraline) "I started using Zoloft on Wednesday the 5th of December 2012. Today's date is the 8th of December 2012. Four days, it has only taken four days for me to feel like a new person. I have been on it before, therefore I know what side effects to expect. Everybody is different, but I suffered from loss of appetite, headaches, nausea, feeling a bit dizzy, lower back pain, and trembling hands. This only lasts for a week or two. I used to cry for no reason (even at work), snap at my partner for stupid things, I was paranoid over everything, socially scared (I always wanted to stay home). I haven't cried since being on Zoloft, nor snapped at my partner. I am a new person now. I'm so happy and look forward to my new life. 100/100."

10 / 10
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  • Blo...
  • March 8, 2013

Zoloft (sertraline) "This medication has turned me around, and I had none of the side effects. I initially requested it from my doctor because, while I did not really have any problems, I had a negative outlook despite trying to be positive, and I was not enjoying 'life' at all. It has really helped with all this, and as an added bonus, I feel that I have more energy. I went back to my doctor and said 'We hit the nail on the head.' Previously, I was looking for the magic vitamin pill to help reduce my stress and increase my energy levels. I tried vitamin B, iron, and multivitamins to no avail. I no longer feel the need to take any vitamins at all. I'll continue to take this as needed and have no reservations about taking antidepressants."

10 / 10
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  • Har...
  • Taken for 1 to 6 months
  • May 19, 2015

Zoloft (sertraline) "This has been a life changer for me. I guess I never realized how depressed I actually was until I started on Zoloft. I'd been fighting it for years, forcing myself to get up and get by each day, but getting worse and worse (avoiding people, having problems talking, having horrible insomnia). Within a week of being on Zoloft I noticed a major difference. I actually feel optimistic about life for the first time in as long as I can remember. My relationships with my wife, family, friends, and coworkers have all improved dramatically. In short, I'm no longer depressed. I had some side effects over the first few days (restless legs, night sweats, a zonked out 'zombie' feeling) but they passed quickly."

10 / 10
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  • Zat...
  • January 28, 2015

Zoloft (sertraline) "Lately I've been having really bad panic attacks, migraines, night terrors/nightmares every night. For three weeks, I started Zoloft last night, and it already started working within a night. I'm more calm and feel like my old self already."

10 / 10
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  • Lou...
  • September 9, 2018

Zoloft (sertraline) "Just take these reviews with a grain of salt. A lot of reviews after taking one day, couple weeks, etc. You need a full three months for maximum effectiveness. Not that it takes that long to start getting relief. Side effects are common while your body adjusts. Some of them will go away. I had no troublesome side effects with Zoloft. I always have to start out gradually. Maybe even more than they say because I’m sensitive to meds. I got big relief from depression. Panic attacks went away. OCD went away. The cons are it made me not very motivated, felt kind of numb to strong feelings. Not feeling urgency about my life. I wouldn’t take it again for years because it blocked my clear perspective. But it was great to get me stabilized. Things that really help but can’t completely replace anti-depression is fish oil, Vit D, exercise, sunlight, folate like spinach, lentils really good. Also, diet really helps. Get a book called the Good Mood Diet. Best wishes"

7 / 10
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  • Joa...
  • Taken for less than 1 month
  • August 27, 2019

Zoloft (sertraline) "I just recently started taking Zoloft. I've been taking it for almost 3 weeks, so not a long time. But I've so far had a great experience with it! I have postpartum depression and anxiety. It was getting very hard for me to get up during the day with my kids and do stuff. I was tired all the time, no interest in anything or going out. Now, 3 weeks on Zoloft, I have started noticing I have fewer compulsive thoughts, I worry less, and I have been going to see my friends more. I still have to kind of force myself to get out and I still have my days, but it’s been working very well for me. I haven’t had any side effects, which is what I was worried about. I almost didn’t take it because I was so worried and fixated on the side effects. My sex drive hasn’t been affected, and I haven’t been nauseous or anything. I take it at night before bed, and it’s just been really great! I’ll update if any bad side effects happen, but so far it’s great!"

9 / 10
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  • Lou...
  • September 5, 2016

Zoloft (sertraline) "I've been on the generic sertraline 50mg for about two weeks, and I feel so much better. I was very depressed, irritable, had insomnia, and felt like a total failure at life. I had a little diarrhea at first, but then I also have IBS so I wasn't surprised. After a few days, that stopped. I feel like my old self again, like a weight has been lifted from my shoulders. I'm even singing again, I haven't done that in about a year. I was in denial for a long time, I told myself I could handle the depression - I was wrong. This is the first antidepressant I've been on, and I am very pleased with how much it has helped me."

9 / 10
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133 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.