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Sertraline User Reviews & Ratings (Page 5)

Brand names: Zoloft

Sertraline has an average rating of 7.3 out of 10 from a total of 4,403 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Sertraline

  • You...
  • Taken for 2 to 5 years
  • January 19, 2024

For Anxiety and Stress "I found this site bookmarked on my web browser today... and it took me back three years ago when I first started Zoloft for the second time. I came on this website multiple times every single day... praying that the medicine would work, and the side effects would go away. The first time I started Zoloft, I had absolutely no side effects. The second time that I started it was a few years later, and I had pretty bad nausea for about an entire month. I was honestly so ready to call it quits both on the medicine and my battle with depression. Honestly, it does get worse before it gets better. I remember thinking at least before I was depressed and not nauseous all the time. Every time that I was so tempted to stop taking the medicine, I would come back to this site and read the posts. I'm coming back here to let you know that it gets better. Three years later, I am married, have the cutest puppy dog, moved out of my parents' house, and my career is thriving... YOU'VE GOT THIS!!!!"

9 / 10
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  • A86
  • April 24, 2019

For Anxiety and Stress "2017, I just started a new job after a year of unemployment. I began to feel anxious at work, and a few months into my new job, I had a severe breakdown. I went to my GP who explained everything to me in detail. She prescribed me anti-sickness tablets for my sick feeling, which did WONDERS immediately, but she also said that I need to give Sertraline a chance to work. Fast forward to 2019, and I wanted to write this review to anyone who was in my shoes in 2017, searching the net for the magic cure, anxious about the future, and feeling trapped and like they will never get better! THERE IS HOPE!!!!!!!! Give the medicine a chance to work, Sertraline saved my life!!!!!!! I am still taking it at 125mg and now looking to lower the dose because I feel so much better, I feel comfortable. I am able to get on the tube like I used to (without anxiety), I can sit in meetings, and I can even present to a crowd now! I got a promotion at the start of this year and loving life."

10 / 10
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  • neris...
  • June 7, 2021

For Generalized Anxiety Disorder "I am a pharmacy technician and been one for over a year now. I had developed GAD due to my job, and it was then taking over my life and mental health. I started losing weight fast. Second time having an anxiety panic attack at work and got sent home early due to my body going to fight or flight mode. My doctor then quickly prescribed sertraline 25mg. Finally, I read all the reviews, and it gave me so much hope that I wasn’t alone. For the first few days, I had the runs every morning bad, increased anxiety all the time, insomnia in the morning, hot flashes during the night, some jaw clenching for the first two days. By week two, all the side effects lifted. By week three, I didn’t notice too much, but my mood was so much better. I finally started eating happily, playing with my family more, sleeping well, and even working out! I finally feel normal again BUT better. Please know that you are not alone, and keep pushing. I am only taking 25mg, and it really does make a difference!"

10 / 10
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Frequently asked questions

  • HapaB...
  • Taken for 2 to 5 years
  • March 24, 2019

Zoloft (sertraline) for Depression "I am a 34-year-old woman who has been living with depression since I was 12. Depression had me feel like I was Atlas (from Greek mythology) with a lifetime of struggle to roll a boulder uphill. Initially, I was against the idea of being on an antidepressant. I finally caved in when a break-up threw me into a tailspin of never-ending crying and sadness. At the doctor's office, he forewarned me that the first 6 weeks are going to be tough and to brave the storm until the medication builds up in my system. I had 3 weeks of side effects that had me feeling more depressed and fatigued. However, I got through it, and my life has changed for the better. Presently, I am more outgoing and actually feel like a 'normal' person again. I am finally truly and sincerely happy and have gained more friends because of that. If you are thinking about trying this medication but are still unsure, take the risk. I can't describe how great it is to finally have your life back."

8 / 10
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  • Anxiety...
  • July 10, 2013

Zoloft (sertraline) for Depression "I've been taking Zoloft for 8 years. It has created stability in my life. Prior to taking medication, I always felt off...anxious, depressed, emotional, dwelling on things, and this interfered with the quality of my life as well as affected my relationships and professional life. I take 50mg and I feel even-keeled and normal instead of a basket case of emotion. Nobody would ever know I'm taking a medication, and I'm often complimented on my temperament. I feel neutral, in control of my feelings, and everything is within normal range. If you are overly emotional, anxious, feel off-balance, and have difficulty feeling consistent in your life...this could help. I feel content and normal now."

9 / 10
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Are you taking this medicine?

  • Julia
  • January 13, 2020

For Anxiety and Stress "I started taking this pill over 3 months ago, because something bad has happened in my life. I had very intense panic attacks and shaking, couldn't sleep, constant anxiety. If you are someone who just started to take these pills, brace yourself: the first 5 weeks are gonna be HORRIBLE. But hold on, it starts to get better afterwards if you keep taking them. I started with 50mg, which was soon raised to 100mg. I got almost every single side effect that was listed in the pill's warning: Shaking, worsening panic and depression, fear of death etc. These thankfully gradually faded after the first 2 weeks. The longest lasting side effect was that I kid you not, I couldn't sleep more than 45 minutes a night for almost a whole month! INSOMNIA! Now I have been on these for almost 4 months. The panic attacks are absent, and even on the worst nights, I can easily sleep 4-5 hours. On weekends, I can even sleep in :) A very tough medication, but in the end, it works like magic!"

10 / 10
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  • Matt
  • Taken for 1 to 6 months
  • March 14, 2024

For Anxiety and Stress "I wanted to take the time to write a review, as reading all those already on this site got me through the first 6 weeks of taking sertraline. I experienced every side effect possible and felt so low I ended up in hospital after a few days of taking them. However, I'm now on week 8, and my life is transformed. My anxiety/depression has pretty much gone, and I can go about my life as normal. My advice - STICK WITH IT, it does get better. Reach out and use the support of your friends and family if you struggle initially."

10 / 10
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More FAQ

  • Sam...
  • Taken for 1 to 6 months
  • May 26, 2024

For Anxiety and Stress "Game changer, BUT be prepared that it might make your depression worse for 2-4 weeks. It made me feel terrible and affected my sleep, but reading the positive reviews on here helped me continue. And I've never felt so good in my life. I can't believe I put off taking medication for the last 20 years. I exercise, work on my mental and physical fitness, don't drink alcohol, etc., but still always battled anxiety and worry. These tablets have 100% stopped these worries!! Amazing. I'm now 3 months in."

10 / 10
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  • Worki...
  • Taken for less than 1 month
  • May 2, 2024

Zoloft (sertraline) for Panic Disorder "They say that if you are living in the past, you're depressed. If you're living in the future, you're anxious. If you're living in the present, you're content. Zoloft has placed me in the present. That's the best way I can describe what this medicine has done for me. Throughout the last 20-plus years of my life, I have dealt with many issues, and this medicine has taken me through it all during my darkest days."

10 / 10
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  • Jc129...
  • August 26, 2021

Zoloft (sertraline) for Major Depressive Disorder "Zoloft saved my life. During my pregnancy, I started experiencing severe anxiety and depression. I was throwing up every single day, missing work, withdrawing from life. I had panic attacks from the time I woke up until the time I went to bed. I dreaded and feared waking up every day and having to be alive again. I felt hopeless, miserable, worthless. It got to the point where I genuinely had urges to hurt myself and thought it would be better if I just died. Cue Zoloft. I started on 50 mg, and within about two weeks noticed small improvements in my energy, but still felt extremely low and incapable. I spent hours on this forum looking for the motivation to keep pushing. Things gradually improved over the weeks, and after about 6 weeks on Zoloft, I woke up one morning and just realized...I felt like me again. I wasn't hopeless. I wasn't depressed. I was able to laugh again. I actually saw my future again. If you're in the same place I was, KEEP GOING! Things will get better!"

10 / 10
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  • Amanda
  • Taken for 6 months to 1 year
  • June 2, 2022

Zoloft (sertraline) for Depression "This medication has changed my life. I used to feel depressed all the time, no motivation to reach any goals, leaving house was impossible, honestly no desire to live life. After 9 months on it I can say I am happy again. I’m laughing at silly things again, I wake up early and want to go outside and LIVE. I’m exercising all the time, meeting friends. Loving life again. I heard someone saying the other day “the worst thing you can do is depend on medication”. Mate I’ll tell you just once, the worst thing IN THE WORLD is to live depressed. Please give yourself permission to use this as a tool for the time that you need. Living life depressed is the worst possible thing and it steals amazing opportunities you could have in life. Depression changes your personality for the worst. I hope that if you’re still wondering if it’s worth it or not to give this a shot, you go for it. Even if it doesn’t work for you and you keep looking for a better fit. Things do get better❤️"

10 / 10
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  • JPhoe...
  • Taken for 1 to 6 months
  • July 4, 2023

Zoloft (sertraline) for Post Traumatic Stress Disorder "About 8 months ago, I began a battle with post-traumatic stress and major depressive disorder. Traumas from years past that I had never faced resurfaced and turned my life upside down. I wasn't sleeping or eating. At one point, I went nearly forty hours without sleep and was considering taking my own life. I suffered terrible panic attacks and had nonstop intrusive thoughts. This went on for months until I started on Zoloft about 13 weeks ago at 50 mg. I noticed a minor improvement over the next 5 weeks. At 100 mg, I noticed much more progress over the next five weeks. Presently, I am at 150 mg and have noticed a major difference. What I found is that Zoloft slows the intrusive thoughts and allows me to access the things I work on in therapy and actually apply them, whereas before, the emotions were too much. This medication takes time to work. I read these reviews during my hardest times, and it really helped me stay positive. Stay strong. Keep working. It gets better. I promise."

10 / 10
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  • Thank...
  • Taken for 1 to 6 months
  • September 8, 2019

Zoloft (sertraline) for Social Anxiety Disorder "I feel so obligated to leave a review. I was sitting where you are now almost 4 weeks ago. I was terrified after reading the reviews, however, I knew I needed help. I had postpartum depression and let it go unchecked for a long time. When that seemed to subside, I was hit with debilitating anxiety that really started to rob me of my life. I had severe insomnia as a result. I started on 25 mg for a week, then went up to 50 mg where I am currently at now. It was a very difficult med to get on. I had increased anxiety, panic, still fought insomnia. After about two and a half weeks and help from my family, I felt like the world felt brighter. Every day since has been getting better. I can’t tell you enough that if you can weather the first 2-3 weeks, you will not regret it. I am getting back to my old self and it feels so good. I am so thankful, and feeling so blessed. You got this!"

9 / 10
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  • Kayle...
  • Taken for 1 to 6 months
  • February 2, 2024

For Anxiety and Stress "I feel compelled to write a review for this medication because of how much it has helped me and how scared I was to take it. Like many people with anxiety, I was TERRIFIED to try medication, but I knew my anxiety was out of control. I was at a point where I couldn't grocery shop or attend any social gatherings without severe anxiety. The first 2 weeks were hell. I couldn't get out of bed, washing my hair felt like the hardest task in the world. My anxiety got so much worse in the beginning. I even had scary intrusive thoughts. My partner stayed with me the whole time and was so supportive, which helped tremendously. After two weeks, I started to notice a difference. The side effects went away and I was less anxious. I am now on week 4 and I have no side effects, and my anxiety is gone. I can grocery shop, go to social gatherings, and live my life in peace. For anyone who is going through the tough bits…I have been where you have been. Keep pushing. It works."

9 / 10
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  • Hope4U
  • March 1, 2020

Zoloft (sertraline) for Depression "Teenage son was on Lexapro, then Zoloft. Gradual transition of 10mg Lexapro + 50 mg Zoloft for 2 weeks, then 3rd 50mg of Zoloft. Next 3 weeks were totally insane with side effects. Week 3, Zoloft increased to 100 mg with 50 mg of Seroquel for sleeping. We wondered if Zoloft was making everything worse, but we hung in there. So glad we did! By week 4, it seemed like everything reached an equilibrium point. It was like - my gosh, what is happening... the depression, anxiety, compulsive behavior went from a 10 to a 3. He was able to control & process thoughts, listen to advice, pause more to think things through before his responses, in general very talkative about everything. Something totally wonderful happened in the 4th week and continues to this day. He is now receptive to knowing the Zoloft medication has pulled him through a very dark place and is now voluntarily open to continuing therapy. For us, the Zoloft medication is working. Yes, it did take time & a lot of patience to see the results."

10 / 10
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  • Brenda
  • Taken for 1 to 6 months
  • November 14, 2019

Zoloft (sertraline) for Postpartum Depression "I’ve been dealing with anxiety and intrusive thoughts pretty much my whole life. After my first baby, my anxiety got really bad. The sleepless nights didn’t help and the general stress of it all. I had never taken an antidepressant because I was a very happy person aside from my anxiety. Once I started Zoloft, it took about a month for me to feel the effects. I’m currently on 50 mg of Zoloft and my anxiety is so much better. I wake up so much happier now, and I can focus on being a good mom and being present. I really recommend this to anyone who is dealing with anxiety and obsessive thinking. Just to note, don’t stop taking the medication if your anxiety increases. The first few weeks were really hard. It’s just your mind adjusting to the drug and playing tricks on you. Stick with it. I promise it really helps."

9 / 10
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  • Firew...
  • January 18, 2021

Zoloft (sertraline) for Depression "I went to the doctor for anxiety and was prescribed Lexapro, which has worked in the past for me, but for some reason it didn’t work this time. The doctor had me stop Lexapro immediately and start 25 mg of Zoloft. I started on 25 mg and increased over the next 4 weeks to 150 mg. Let me just say the next few weeks were horrible, and reading these reviews encouraged me and made me want to push through. I skipped over all the bad reviews to stay focused. I took Xanax at night just to help sleep but just powered through the day with nothing. I had lost 27 pounds in 5 weeks. I was beginning to think it wasn’t going to work. On the 5th week, I got up and couldn’t walk. Let me just say I felt a big difference going into the 6th week. The medicine finally kicked in. God heals by miracles and by medicine."

10 / 10
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  • DomB
  • March 16, 2016

Zoloft (sertraline) for Panic Disorder "I read these reviews, body tingling, shaking, concentrating on every breath or I would choke to death, using all of my will to focus on these reviews with tears in my eyes imagining that some of these success stories could happen to me and promised to write one if I could make it out alive. I'm 22 and started having severe panic 2 years ago. Don't worry about the side effects. If your experience was like mine every day, side effects would be a break from the dread and torture I felt every second. Zoloft brought me right back to the person I remember being before the panic. Just try it and give it time. It gradually got better over 3 weeks along with klonopin for attacks in that time. I hope this gives someone the hope and courage to try it."

10 / 10
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  • fira
  • Taken for 1 to 6 months
  • February 23, 2020

Zoloft (sertraline) for Social Anxiety Disorder "I was very anxious and used to overanalyze everything. Now I am confident and do not really care much about what people might think. This medication made me also a lot happier. I've been taking it for about 5 months now, and I've never been as confident and rooted as I am now."

10 / 10
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  • Magood
  • Taken for less than 1 month
  • August 15, 2019

For Anxiety and Stress "I have been on sertraline since 9 days ago. I had all of a sudden generalized anxiety which progressed to panic attacks without any obvious reason. My doctor has prescribed me sertraline 50 mg once daily and told me that may make me sleepy. In those 9 days, I had the worst nausea and loss of appetite with internal shakes. The first day had nightmares. Elevated anxiety and panic attacks especially in the morning. Almost every day I refer to this site to reassure myself that everything will be okay. I will keep you posted. Please wish me luck."

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  • Mr Tune
  • April 30, 2019

For Anxiety and Stress "27-year-old from the UK, Carlisle, on 50mg Sertraline. This medication is excellent. I have tried: Prozac (impulsive & diarrhea), Mirtazapine (5-stone weight gain), Citalopram (severe depression resulting in a constant stream of suicidal thoughts, NEVER AGAIN!), Venlafaxine (severe anxiety and nervousness), Amitriptyline (sedation). I have been on this for 2 weeks. When it started working, I felt happy and calm. I didn't wake feeling angry and fed up with life. My memory has improved, and my sleep has improved. I can go outside, which I was unable to do before. I don't comfort eat, I don't ruminate over negative things, I'm interested in my hobbies again, and I am more outspoken and unafraid of confrontation. It is out of this world! Keep trying and don't give up. You will wake up one day out of this waking coma and see the color of reality again, just keep trying different medications. No matter what, keep going! I have been depressed and anxious for years, this has truly saved me from oblivion."

10 / 10
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  • Daddyo
  • August 20, 2020

For Depression "Comments abound on this page regarding Sertraline's negative side effects. I don't understand why people bother to leave negative feedback as all side effects mentioned are in the information leaflet that come with the medication. Furthermore, most negative reviews are from folk who have not stayed on this medication long enough to experience anything positive. You need to give it at least 8 weeks to see the benefits, if you don't you may be missing a glorious opportunity to get better. Your doctor should tell you these things beforehand."

8 / 10
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  • Deedee
  • Taken for 5 to 10 years
  • September 11, 2018

Zoloft (sertraline) for Depression "First of all, I wanted to write this several years ago but somehow never got around to it. Zoloft has changed my life. I’ve struggled with depression and anxiety my whole life. In 2011 I finally started Zoloft. The first night I started my 25mg dose. The next morning I woke up and felt completely different. It was like a euphoric feeling. My body didn’t ache. I had more energy... fast forward 7 years. I still am using Zoloft and it has made me a better wife, more patient parent and overall less anxious and depressed."

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  • Char
  • Taken for 1 to 6 months
  • June 14, 2019

Zoloft (sertraline) for Obsessive Compulsive Disorder "Been going up slowly on Zoloft to help my OCD. I started on 12.5 mg for 2 weeks, 25 mg for 3 weeks, 37.5 mg for 2 weeks, then 50 mg for 3 weeks, now 62.5 mg. Overall, I’m feeling better. Intrusive thoughts related to harm OCD have gone. General anxiety is still there but not constant. When I started this medication for OCD and panic attacks, I was literally having panic attacks every hour due to the OCD. My anxiety was at a 10, now, most days it’s 0-2. Every day I do have some sort of anxious feeling, but for the most part, it’s a fleeting feeling. BEST THING ABOUT THIS MEDICATION... I LOST 20 lbs and continue to not want to eat junk food. I also started working out. Good luck! I wish you the best and hope to continue getting better with time."

8 / 10
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  • Johnn...
  • Taken for 1 to 6 months
  • September 10, 2014

Zoloft (sertraline) for Depression "I'm 19 and Zoloft has been a LIFESAVER for me! I've had very bad generalized anxiety, social anxiety, panic attacks, and mild depression. I recently had been on Xanax then Klonopin as needed, but I felt as if those types of medications wouldn't help me in the long run. I've been on 25 mg of Zoloft for a month and a half, and I feel WONDERFUL! The horrible, disabling anxiety I once had is almost nonexistent, and my depression melted away! My mood is stabilized, I have a lot of energy, focusing on school work is a synch, and I interact with others with confidence. Yes, I feel like a totally renewed, cleansed person with a constant sense of motivation! Zoloft saved my life! Little to no side effects either. Very mild antidepressant."

10 / 10
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303 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.