Secukinumab for Psoriatic Arthritis User Reviews (Page 2)

• SamiC
• Taken for 2 to 5 years
• December 23, 2017

Cosentyx (secukinumab) "Have been on Cosentyx, monthly, along with methotrexate, weekly, going on two years for psoriatic arthritis. After about a year, my finger joint pain, stiffness and swelling seemed to lessen quite a bit to the point where I didn’t need to take an anti inflammatory on a regular basis. A couple of months ago I experienced a very bad flare up which seems to be getting worse. Also a recent X-ray of my hands shows increased joint damage, which leaves me to wonder if the Cosentyx is actually working. My Rheumatologist wants to double the Cosentyx dose to see if it makes a difference before she starts me on Humira. I’m wondering if Humira is consistently more effective for PSA than Cosentyx?"

• Ettenna
• July 7, 2017

Cosentyx (secukinumab) "One week after the 5th loading dose of 300 mg, my lips swelled to twice their normal size, became itchy and then erupted in blisters. My gums became sore, itchy and throbbing. I got a very red eye and began having itching on various other body parts, starting with my toes."

• Xytne...
• Taken for 1 to 6 months
• September 4, 2017

Cosentyx (secukinumab) "Excited to be starting this Biologic as hospital team assured me it was really suitable for the effective treatment of my psoriatic arthropathy and psoriasis. By the fourth weekly injection I had had two chest infections and the most horrible urinary tract infection. Three lots of antibiotics and a 7 lb. weightloss due to being so sick, I admitted defeat and didn't take the 5th dose. Admittedly the arthropathy eased slightly during the injection period but this was more likely due to the enforced bed rest due to being so ill than to the effects of the Cosentyx. Goodbye Cosentyx. Going back to Arcoxia."

• Longago
• January 28, 2021

Cosentyx (secukinumab) "55+ years of psoriasis and 10+ years if psoriatic arthritis. In the past with Enbrel (caused multiple shingles breakouts), methotrexate (minimal impact on the arthritis). 2 1/2 years ago started on Cosentyx with amazing results for the first 18 months. After that overall health declined. Started with loss of taste which progressed to severe pain on swallowing, debilitating ear aches, runny nose, oral blisters on gums, swollen gums, thrush. Made the decision to stop Cosentyx. Gradually the impacts from the toxicity of cosentyx are dissipating. All the psoriatic symptoms are back, as was expected, and worse than ever. I'm giving my body a year to re-set before I try anything else. It's a setback physically with the joint pain, but the side-effects caused by Cosentyx as it built up in my body were scary. Stumped multiple specialists about what was going on as much of what I was experiencing was not listed as known side effects - they are now."

• Anonymous
• Taken for 6 months to 1 year
• October 20, 2019

Cosentyx (secukinumab) "90% cured my terrible PS skin. 70% improvement in my joints but jaw still v sore. Knee swelling there still but big improvement in back and neck pain. Ankles have improved too. Was in 160mg now taking 300mg hopefully it will help more"

• HENNY
• Taken for less than 1 month
• September 23, 2018

Cosentyx (secukinumab) "Getting ready for my third 300 mg dose. I get nausea all the time. I just don't feel right. I have IBS and have been under control for some time. It has flared up now. I know its just been three weeks, but my fingers are no better and very painful. If this continues after finishing the recommended dosing of 4 weeks, I'm not going to continue. Not worth it if you have to deal w all the side effects and still have pain."

• Just...
• Taken for 2 to 5 years
• February 12, 2021

Cosentyx (secukinumab) "I have been on Cosentyx for almost 3 years and it has done great for my skin but not much for my psoriatic arthritis which attacks the tendons throughout my body, mainly the lower half (ouch). I have experienced palpitations for a couple of days after injecting the (300mg) and only a couple of hours worth of palpitations after injecting the (150mg) and both injections cause golfball size injection lump that itch. I do believe this drug also interferes with my thyroid levels (I'm thyroid-less)so definitely pay close attention to your thyroid health and thyroid symptoms while on this biologic and any biologic. The weight gain is definitely real no matter what the manufacturer or your Doctor says."

• Laika
• Taken for 1 to 6 months
• November 16, 2017

Cosentyx (secukinumab) "After the initial phase I got very sick and my psoriasis has not improved at all. Runny nose ( like really bad) chills, hives, plenty of pimples everywhere and really tired . Hair Follicles infected. Bad medication"

• BALTO
• Taken for 1 to 2 years
• September 26, 2018

Cosentyx (secukinumab) "I have only had two injections so far, and I can't wait to take the 5 weeks of cosentyx. My joint pain is tremendous. Psoriasis is the same, I'm very hopeful. I will let you folks know after my weeks "

• Anony...
• Taken for 1 to 6 months
• November 24, 2020

Cosentyx (secukinumab) "This medication should come with a caution sign all over it! If I could leave a negative rating I would. I lost 50 lbs in 2 months and went into liver failure. I was a skeleton. I couldn't walk or even eat. This drug gave me stomach aches that were so severe, I ended up in the hospital a couple times. It was so hard for me to do anything but I had to force myself if I wanted to survive. I nearly died from this drug and I am only 18 years old. I ended up having Crohns disease as well but my doctor had no idea at the time of this medication. Therefore, the extreme stomach pain and nausea. The smell of food made me throw up. Before this drug I was on Humira, then Enbrel, (then Cosentyx), then Stelera, and finally Cimzia. Now trying Simponi in hopes something will work. I even tried xeljanz and no luck."

• Jay
• Taken for less than 1 month
• January 26, 2019

Cosentyx (secukinumab) "I had a major reaction to cosentyx. I was in the hospital for four days after the third injection. I ended up with a large hive on my upper leg that took three weeks to go away. I had a fever over 104 degrees and an infection. My white count was off the charts my inflammatory markers were 20. One to two is normal. I had to have intravenous antibiotics because I couldn’t keep anything down. No one wanted to believe it was the meds until skin biopsy came back. The pathologist sent it for second opinion and it came back as hive. The cause on the lab work was medication. My first sign something was up is that it caused me to break out with psoriasis."

• Lady
• Taken for less than 1 month
• May 31, 2018

Cosentyx (secukinumab) "I just started taking Cosentyx. I was on Humara for my psoriatic arthritis which did nothing but make my hair break off and make me extremely tired the day after the injection. The negative to all these drugs is that they suppress your immune system making you more susceptible to other illness. I am struggling at work to type and do simple tasks so I am really hoping the benefits out way the side effects."

• Anonymous
• Taken for 1 to 2 years
• May 22, 2018

Cosentyx (secukinumab) "Cosentyx is working for me and apart from the runny nose for a day to two after taking, I have not had the listed symptoms. However, I have experienced a rapid increase in my allergies and sensitivities to the point where I carry Epipens again and cannot be in a room with peanuts (anaphylaxis). Another strange thing, my periods are so heavy(embarrassingly so) I prefer to be at home and have had to have an iron infusion. As these are not listed side-effects, my specialist is sceptical. There is nothing else to explain these. I am considering whether to get off the drug as the period thing is negatively effecting my life and there not many solutions, however this is the only drug that has worked for me (but for flare ups). Also re painful injection sites - I use relax as much as possible and use lotion on the site after the injection which seems to help with the itches, redness and burning"

• Anonymous
• Taken for less than 1 month
• August 13, 2021

Cosentyx (secukinumab) "I was put on cosentyx by rheumatologist as first line biologic, I was very keen for this drug to be my miracle but unfortunately it was a nightmare. After first injection a day later I had a rash begin in my bum and very sore and inflamed, the pain then moved into my bowel giving me bad lower bowel pain. My rheumatologist sent me for a colonoscopy looking for ibd? Colonoscopy came back clear and I was told to proceed same thing happened on next injection pain so bad didn’t sleep for days, I proceeded with third injection after being told it will get better, it definitely did not and I was living with no sleep severe pain and couldn’t go to bathroom. I have stopped cosentyx 2 months since last injection and on probiotics and medicine to calm my digestive system to heal still very sore. No diarrhoea or blood but very painful. Please if you get these symptoms don’t proceed stop and try another biologic I am now on humira and no problems"

• Canad...
• March 9, 2021

Cosentyx (secukinumab) "I took the load up doses of 6 one week injections when my body reacted 10x as bad as any case of psoriasis I ever had. My joints felt numb and my reflexes were dulled with stomach trauma a side effect during this load up period. I made a decision to stop the injections and I have to admit even with joint pain and severe psoriatic breakouts I feel better! It’s been more than three months since termination of Cosentyx and my psoriasis breakouts are starting to clear up but seem to be lingering longer than ever before. My reliance on sunshine and healthy diet are now my only solution to controlling psoriatic arthritis now. I hoped I could find a solution in a drug but now I know drugs don’t fix the problem but diet and exercise can."

• Frida
• Taken for 1 to 6 months
• January 23, 2023

Cosentyx (secukinumab) "Self diagnosed PsA confirmed by a rheumatologist. Tried Etanercept no change, methotrexate alone not much difference. Then Cosentyx 150mg, 4 + 1 loading dose, then monthly, and now I am on month 3. The worst pain ever experienced, both hands, all fingers, wrists, elbows, hips, knees and neck - the pain went off charts. I cannot use my hands at all, enthesitis everywhere as of Dec 10. Here we are Jan 23 getting worse day by day. Also weird gastro stuff. I either need more, an additional med or none! This is terrible and so disappointing. Utter disability, cannot leave the house. My heart goes out to you all if in a similar situation."

• Mad4R...
• Taken for 1 to 2 years
• November 23, 2020

Cosentyx (secukinumab) "If PsA is mainly in SI joints & back, Cosentyx may be effective. Diagnosed w/PsA in 1997. Prior to that, pustular psoriasis on soles of feet and palms of hands. Prescribed Enbrel soon after 1st available, effective for 15 yrs, except for SI joints (still needed bi-lateral knee replacement, rotator cuff surgery & two foot surgeries, not all PsA.) 4 years ago I experienced repeated venous ulcers & stopped Enbrel. After ulcers resolved, was put on Otezla - no help w/PsA. Switched to Cosentyx, initially good and no side effects. However, after a year, began to experience serious joint swelling in my fingers. Cosentyx helped w/ the SI joints - those are mostly pain free. But swollen fingers = constant pain. Dr. is adding Arava - avoiding Methotrexate because of diminished kidney function. Effective Jan 2021, Cosentyx no longer covered by my insurance, too $$: choices are Enbrel or Humira. Probably back to Enbrel & heightened concerns over infections."

• Holly
• Taken for 1 to 6 months
• August 8, 2020

Cosentyx (secukinumab) "I have had psoriasis since the sixth grade. I am 60 now and have endured psoriasis and psoriatic arthritis for the past 7 years. The pain and fatigue are debilitating. I tried Methotrexate, my hair fell out and my liver got messed up. Doc put me on Humira, no help. Started Cosentyx 6 months ago. Started at 150 mg now up to 300 mg. At first everything was great. I thought I had found my cure. Unfortunately my psoriasis is starting to flare. I have spots by my ears, my neck, the middle of my back and my upper arm. I am miserable. I’m asking my dr for a referral. I’m desperate"

• Dawn...
• Taken for 2 to 5 years
• March 30, 2021

Cosentyx (secukinumab) "The company that males this should be ashamed of themselves. I have called several times to report my medicine did not get delivered each time I was on hold 48 minutes to a hr and a half before I hung up ."

• R A H
• Taken for 1 to 2 years
• June 6, 2023

Cosentyx (secukinumab) "I’ve been taking Cosentyx for one year for psoriatic arthritis. It’s been the second best medication I’ve been on (have also tried methotrexate, Humira and Enbrel). The injection is the least painful of the ones I’ve tried and the dosing is once per month, which isn’t too frequent. I have not experienced too many infections like I have in the past on some other drugs. It’s worked pretty well for me, although I still have active joint pain so my doctor has recently uppped my dose from 150 to 300mg. Don’t be afraid to try it! It could work for you too. Even after an year+, I am still improving. Every drug is different for every person. My disease activity is high and considered severe, and I am able to work full time and manage pretty well with Cosentyx. I do not notice any extreme or intolerable side effects; anything minor is worth it for the potential benefit."

• 04-07...
• Taken for less than 1 month
• June 20, 2023

Cosentyx (secukinumab) "I got both a fungal and bacterial infection. I've been fighting Necrotising Granulamatosus inflammation since the 4th dose. I stopped after the 5th dose. After 7 biopsies and almost 5 months and I'm still fighting this inflammation. No treatment for it either. I have nothing positive to say about this drug."

• Sandra...
• Taken for 5 to 10 years
• March 23, 2023

Cosentyx (secukinumab) "I have used cosentyx for several years. It has worked really well. I have some plaques, but mostly they are clear. I have had no infections at all. I haven't even had a cold in years, no illnesses not even covid. I haven't noticed any side effects at all. I use the150 mg/ml, one injection every 28 Days. I used two pens per month in the beginning and it cleared me up really well, but my doctor cut it back to one pen and I am fine with just a few plaques. I've had psoriasis since I was 3 years old it's been a lifelong fight against psoriasis and arthritis, I'm 76 now. It's a blessing."

• AJano
• Taken for 1 to 6 months
• October 2, 2019

"I have been suffering with psoriasis from one year and arthritis 2 months... secukinumab cleared my skin, scalp and I can see major improvements on nails .... and my arthritis pain had almost went in remission when I took injection at first flare up of arthritis and it’s my first biologic...."

• Rayman
• Taken for less than 1 month
• October 8, 2018

"Got psoriatic arthritis at 15 years old and the flareups were brutal. I'm ale and 22 years old now and been bed bound for 8 months. Psoriasis 100% body and all joints affected. The drugs didn't work so I'm currently on cyclosporine 100mg twice daily, methotrexate 25mg and cosentyx. My skin is all clear. I have some pain in hip and wrist. I am now walking to exercise and am quite hopeful."

• Phyllis...
• Taken for 2 to 5 years
• April 26, 2022

Cosentyx (secukinumab) "Went to the dermatologist and was diagnosed with psoriasis. She put me on Methotrexate. Went back for follow-up and showed her I had a toe that was red and swollen. The methotrexate was not working. She switched me to Stelara and referred me to a rheumatologist. The rheumatologist switched me to Cosentyx and diagnosed me with psoriatic arthritis. I took the Cosentyx for about a year. The psoriasis cleared up and the arthritis in my toe cleared up. Did not have any side effects. I asked my rheumatologist if we could try Otezla, since it was a pill, and see if it worked. Did the Otezla for a year and by the end of 6 months my psoriasis was back with a vengeance. It was worse on my head. I could lay my hand on top of my head and feel the raised places. It was awful. Went back to Cosentyx, about 6 months ago. We did 4 loading doses and then once every 28 days. The psoriasis was cleared up by the 5th dose. The arthritis in my hands, particularly my thumbs, is awful."