Nurtec ODT for Migraine User Reviews (Page 3)

• Blu...
• October 17, 2020

"Nurtec ODT does not work on Excedrin rebound/medication overuse headaches. I took one Nurtec ODT 12 hours ago, and it maybe dented the pain slightly, temporarily. No nausea. I either have a migraine, a headache, or an Excedrin rebound headache. The over-the-counter (OTC) pain reliever Excedrin combines caffeine 65 mg/caplet, aspirin 250 mg/caplet, and acetaminophen 250 mg/caplet. My habit is currently 3 Excedrin per day. I take an Aimovig shot 1x per month, which helped the first 2 months with many Excedrin and pain-free days. I took Imitrex 2x in 24 hrs yesterday, and it reduced the pain level and put me to sleep but did not work very long. When I could feel the Imitrex wearing off, I took the Nurtec. Nurtec, Aimovig, and Imitrex, and the migraine is still there. My doctor gave this to me to stop the rebound, but it has failed on rebound duty."

• See...
• Taken for 1 to 6 months
• December 28, 2021

"Nurtec relieves my migraines within 1-2 hours, with little to no side effects noted. However, since I started taking Nurtec on an as-needed basis, my migraines are occurring more frequently. I used to get migraines every 2-5 weeks. Now, I am getting them every 1-9 days. I can’t find literature that reports this as a side effect. Has anyone else experienced this?"

• Jen...
• Taken for 2 to 5 years
• December 20, 2022

"Amazing - I take one, and my headache melts away within one hour max. I have reduced headaches down from 15+ to 3-5 days a month, and I take Nurtec, and it’s gone. So glad to have found this after years of pain. I get hormonal migraines."

• Pai...
• Taken for less than 1 month
• March 15, 2025

"I recently tried Nurtec ODT (rimegepant) for my migraines, and while it did relieve my migraine, the side effects made it difficult to justify taking it again. I want to share my experience to help others decide if it’s the right option for them. 1. Effective Migraine Relief I’ll give Nurtec credit where it’s due—it worked for my migraine. Within about 1-2 hours, the pain significantly reduced, and I was able to function again. The relief lasted for over a day, which was impressive. 2. Severe Nausea & Stomach Pain The downside? The nausea hit me hard. Shortly after taking it, I felt waves of stomach discomfort and queasiness that lasted for hours. I tried taking it with food, but it didn’t seem to help much. The stomach pain made it difficult to enjoy the relief from my migraine. 3. Lingering Fatigue Even after the nausea faded, I felt drained and sluggish for the rest of the day. It was almost like a migraine hangover."

• Mic...
• Taken for 1 to 6 months
• March 17, 2021

"After suffering from terrible headaches and migraines for years, I have finally found a treatment through this. The relief kicks in shortly after taking a pill, and I am so glad that it allows me to get back in motion."

• Jan...
• Taken for 1 to 6 months
• November 15, 2020

"I have migraines with visual aura. I take Nurtec as soon as I start to see the zigzagging lights. I think it helps head it off, but I also take 2.5 mg codeine, so don't know if it's the codeine or the Nurtec. I don't think it's worth 90 bucks a pill."

• Sth...
• Taken for less than 1 month
• May 6, 2023

"Oh my gosh… This medication made me feel like I was on my deathbed! I took it for the first time yesterday due to a migraine I had on the same day I visited my doctor. It seemed to work for a bit, but then things took a major turn for the worst. A couple of hours after taking this pill, I completely blacked out and was unconscious. I woke up only because I was aspirating on my own vomit. I ran to the bathroom, and it was a horror movie scene. I then was violently ill; throwing up within 5 mins of taking a sip of water. I threw up constantly for around 5 hours and laid in my bathroom, in the dark, with a blanket and pillow. I did not mix this medicine with any other medicine that night either. My migraine got worse, and I’m still fighting it today (approx 20 hrs after), and by then I was terrified to take even a Tylenol and another Zofran because I was so extremely sick! Be careful with this medication! It may work for some people, but just looking at the bottle is giving me PTSD now."

• gin...
• Taken for 1 to 2 years
• November 16, 2022

"I started taking Nurtec over a year ago. It worked really well for my migraines, and my headaches were gone within an hour from taking it. Almost immediately, my hair started falling out. I didn't think anything of it, I thought it was stress, but as time went on, handfuls of hair would be in my hands and in the shower drain after every shower. Over time, it really started to bother me, and my hair is very, very thin. I had blood work, I've had my thyroid checked, I've been to a dietitian, I've been to a dermatologist, I've been to my gynecologist, and my thyroid checked. I've gone through a litany of tests for hair loss, and everything is fine. The only thing that's left is Nurtec. I stopped taking it 3 weeks ago. My hair is still falling out, while not quite as bad. I believe Nurtec takes approximately 3 to 4 months to get out of my system. I'm hoping it stops soon, otherwise, I'll be bald."

• Anonymous
• Taken for less than 1 month
• October 7, 2022

"I've taken several types of triptans, and sometimes they take the edge off, or if I take them very early in the day, by night I might be feeling a bit better, able to sit on the couch with my kids-but still no normal function. So I thought I'd try Nurtec because of the hype and recommendations. This was definitely not for me. I felt drugged up. I was bursting into tears, acting weird, asked my sister to pull over to the side of the expressway because I thought I was going to vomit while she was getting me home (it was a sudden urge rather than general nausea). And then I was in a 'haze' for a couple of days. It's definitely not something that I ever want in my system again. I'm a slimmer woman and also wonder why the same doses are given across the board. I'm definitely sticking with my triptans (Frova, Nara)."

• Dal...
• September 28, 2020

"I have suffered with menstrual migraines for around twelve years. I am so grateful for this medication! It’s a game changer for me! I highly recommend. No side effects at all. Gone within an hour and a half!"

• Flo...
• Taken for less than 1 month
• December 27, 2021

"1st use caused a panic attack (PA). I was desperate, so I took it before doing my normal research, but I started research shortly after taking it. The first thing I saw was a Kardashian name. I wouldn’t have taken it had I seen that first, as I feel it speaks volumes. The PA that this set off rolled for hours. Also, I now know (thanks to research) the CGRP is involved in wound healing and protective measures for the cardiovascular system, among other things. I don’t trust the long-term safety of this drug. I’ve never had a reaction like this to a drug and haven’t had enough PAs for me to think that the PA was a coincidence. This drug is the only known trigger for my PAs. I won’t even donate what I didn’t take because I feel such conviction when it comes to this medication."

• Goa...
• Taken for less than 1 month
• September 28, 2022

"The one dose of Nurtec was great until it wore off. Then I was left with paralysis on my left side, which included my leg, arm, and face. I could not roll over in bed or get out of bed without assistance. I could not walk unaided, let alone drive a car. I could not shower standing up. I had horrible pain all over, so I would sit in the shower letting the water wash over me to feel better until there was no more warm water. I had diarrhea and urinary incontinence. I wanted to sleep constantly. I could not think clearly or speak very well. I was not hungry and more. This went on for 3 months, I lost 40 pounds. My heart rate increased to 110 and has stayed around 100, even now 8 months later. I could not tolerate being outside in the heat. I cannot lift more than 20-25 pounds. I went to my PCP, she treated my symptoms. Poison control said there was nothing to counteract. Most of my symptoms have gone, but some remain. I never had most of these before. Horrible pill."

• Ano...
• Taken for 6 months to 1 year
• April 5, 2021

"I started taking Nurtec about 6 months ago, and it has really worked for me. I take it as soon as I feel, 'yup, this is actually a migraine' vs. a tension headache, which has been about once a week these last 6 months. It usually takes about an hour to set in, but the pain melts away, and I can get back to normal life mostly. I can still feel the migraine creeping under the surface, so I would say it gets me back up to 85% of my normal self. I have had no rebound migraines, but a couple of migraine hangovers the next day."

• Sar...
• January 29, 2023

"I wanted to leave a review since I figured most people who bother to leave one only do so when they have a negative experience. So for those of you who rely on reviews to make your decisions as I do, I just wanted to leave my own experience. I tried my first Nurtec today after avoiding it for a while out of fear that I’d have a negative reaction. I wish I had taken it before during my last two migraines because the only side effect I had was VERY mild dizziness. So mild that I could shower and walk around and feel fine. Other than that, no nausea, no stomach pain, nothing. My headache is gone and I feel completely fine. So grateful for this medication!"

• Anonymous
• August 25, 2021

"My neurologist prescribed this to me along with Reyvow and said they were the newest and best for migraine pain. These two meds do not work for me! It was a ratio of ~1 to every 10 times I have taken these pills that they actually worked. Migraine usually came back a day or so later when it did work. Reported this twice to my long-time neurologist, her plan, take lots of magnesium, ginger root, and an antiemetic when I feel a migraine and then the med combo! I am not new to migraines, been getting them since I was 7 (I just turned 61), so lots of meds and experience with these headaches. I finally had to fire my doctor and move on. I hope I can find something other than Nurtec with my new doctor."

• Anonymous
• Taken for less than 1 month
• December 16, 2022

"I just read in the comments this contains sucralose! I'm extremely allergic, and my doctor knows about this but prescribed it anyways as a rescue medication. I've been bedridden for almost 6 days and went to take it again. Good thing I looked at these reviews. If you have an artificial sweetener intolerance, don't take it. I haven't been able to move, vomiting, nausea, increased pain, etc."

• bun...
• December 19, 2022

"So right off, I was afraid it was gonna taste bad. It didn't taste bad, it was minty, but it did leave a really strong aftertaste, like metallic or bitter. It made me feel really weird, like whooshy. And I felt like I was talking really slowly. And I stuttered a lot. I felt really floaty, and I had a hard time walking. And the nausea was so bad. Worse than migraine nausea. Like I was salivating like I was going to throw up. But I didn't. My tongue also felt really weird, and I did look in the mirror to see if it was swollen, it wasn't, it just felt weird, like numb. And I ate a little piece of fudge. It tasted like pure butt. In fact, everything tasted bad. Even water. And I still had a migraine. It didn't progress any further, pain-wise. Just like it was at a standstill. So I took it around 12:30 PM in the afternoon. And the migraine finally disappeared around bedtime, about 10:30. So the only thing it really did was stop the migraine from progressing to further pain."

• Anonymous
• Taken for 1 to 6 months
• July 22, 2021

"On the 3rd month of Nurtec now. It does work for me and gets rid of the migraine, and I only take 1/2 of a tablet. Not easy to break in half perfectly, but works just as well as the full tablet, so for those of you who haven't tried just a half, I definitely recommend trying it. The first few times taking it, I had no side effects. However, now when I take it, I get lethargic and sometimes so tired I literally can't keep my eyes open and have to lay down. It also gives me terrible heartburn and sharp pains in my stomach and gut, as well as some stiffness and joint pain, so I'm starting to wonder how safe it is, especially in the long term. Zolmitriptan 2.5mg works better for me with fewer and shorter-lasting side effects."

• Non...
• Taken for 1 to 2 years
• June 15, 2022

"Minimal relief. Exorbitant copay of $370 with insurance coverage. Unable to take triptans due to brain aneurysms. Other CGRPs pretty much worthless. Botox helps, but wears off in about four weeks. Lidocaine injections help for a few hours. Wish they would just give me a big dose of Demerol and knock me out. Spent six days in the hospital with a hideous migraine. Given Gabapentin, magnesium, DHEA, you name it. All just drug you up so you can't tell them you are suffering. Unless you deal with this condition, you have no idea the suffering. Not a headache, it's a neurological event."

• Hop...
• Taken for 1 to 6 months
• November 15, 2022

"I was excited to try Nurtec as a preventive, although very hesitant to discontinue Maxalt, which was like a miracle drug for me after 40 years of migraines and trying treatments with neurologists in three states. Keeping records for all these years, I maintained between 8-12 headache days a month on average (some of these days were 3-day migraines, and yes, I was taking Maxalt for those three days). I started Nurtec in July of 2022, every other day as instructed, and saw no significant difference, and was allowed to continue taking Maxalt for headaches, according to my neuro. However, my headache days went down to 5 in August - a first!! - and again in September and October - I'll take it!! Now it is November 15, 2022, and I have not had a headache yet this month. This is unbelievable to me. My takeaway is that, for me, it is taking some time to have a real effect. I will stick with it with fingers crossed for a headache-free month!! I am 62 years old and hopeful!!"

• 4Kr...
• Taken for 1 to 6 months
• May 8, 2022

"Made me super sick! The joint pain and muscle pain I get for days after taking this is absolutely scary! Gets rid of my migraine, but the side effects are not worth it. I’m on steroids in hopes of the muscle aches going away."

• dir...
• Taken for less than 1 month
• September 20, 2021

"This is supposedly an oral dissolving tablet, but the pharmacist said to take it with a glass of water and swallow it. Thank God I did because no one told me it was peppermint. I am allergic to peppermint, and it burned like fire, made me nauseated to the point of wanting to throw up. Luckily, I had some Jell-O and ate that quickly and put out the fire. The migraine got worse. It did not work for me. I will never take this again."

• Mic...
• March 15, 2021

"My doctor ordered me the Kyleena IUD for heavy bleeding. I started having awful migraines several months after it was inserted. My doctor said hormones are 99% responsible for migraines. I started to take Imitrex and was a zombie on it and had to go to bed. I went to my neurologist and he prescribed Nurtec ODT. When my first migraine hit, I was in excruciating pain, and the box was extremely difficult to open. I tried to open it, but being in that much pain made it even harder. Once the package was opened after 5 minutes of trying, it started to work in 30-40 minutes. I have never had a migraine leave so quickly. I was not nauseous or even tired after it worked, and I basically could go back to my normal daily routine. It is a huge blessing that I live in this day and time that we have drugs like this one available to us!"

• Deb...
• Taken for 1 to 6 months
• July 2, 2024

"Amazing. After reacting poorly to several other migraine medications, Nurtec has been a lifesaver! With a connective tissue disorder and chronic migraines, it can be easy to have days robbed out from under you with pain. Nurtec helps."

• Hea...
• Taken for less than 1 month
• February 19, 2023

"I’ve taken it 4 times. The first time I felt better for about 6 hours. The next 3 times it has done nothing. I am also on my first injection of Ajovy. I suffer from “post concussion syndrome” and “post traumatic headaches.” The neurologist puts migraine nonintractable without aura on my medical notes as well. This is all due to a car accident. I was really hoping this would be the miracle drug I keep hearing about. I’ll probably finish out this pack. I can’t take triptans or beta blockers. I can’t take OTC NSAIDs more than 2 times a week. I have headaches and migraines daily, 30/30 days a month. I’ve tried the Cefaly device (didn’t work). The only thing that seems to decrease the intensity and make me feel a little better is sleep. I really wanted the Nurtec to work, but so far it doesn’t seem to do a thing. I haven’t had any side effects from Nurtec."