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Nurtec ODT for Migraine Prevention User Reviews

Rating: 6.5

Nurtec ODT has an average rating of 6.5 out of 10 from a total of 58 reviews for the treatment of migraine prevention. 55% of reviewers reported a positive experience, while 26% reported a negative experience.

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Reviews for Nurtec ODT

Commonly mentioned side effects
  • Nat...
  • Taken for 6 months to 1 year
  • February 21, 2025

"This has been a life-changing medication. I would have 10-20 migraines a month, and now I'm down to 2-4 migraines a month, and it makes the pain less 90% of the time. I end up with mild headaches that are easier to handle."

9 / 10
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  • azs...
  • Taken for 1 to 6 months
  • May 16, 2022

"After about a month on Nurtec, I developed an initial allergic reaction resulting in chronic dermatographic urticaria, esophagitis, and difficulty swallowing. The esophagitis and difficulty swallowing began to occur before the hives appeared and are still an issue. It's been over a month since I have been off the medication, and it seems some of the side effects may be more permanent than I had hoped. I am being seen by an allergist, gastroenterologist, and my neurologist to get me back to normal. Please be careful with this medication, it seems the effects on the immune system and healing are not entirely clear yet. The medication did work very well for my migraines, but I would rather have migraines than what I'm dealing with now."

1 / 10
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35 Report
  • Nev...
  • Taken for less than 1 month
  • August 24, 2022

"It is 5 a.m., and as I’m writing this, I’m lying on my bathroom floor in a fetal position. Ridiculous that I’m writing this now, I know, but I don’t want anyone else to experience this! I took my first dose of Nurtec at around 7 p.m. I felt fine for the first few hours, and then the debilitating abdominal pain started. For the last 8 hours, I have been doubled over with excruciating abdominal pain. So bad that I have almost called 911 multiple times! Please, please be careful taking this stuff!"

1 / 10
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25 Report

Frequently asked questions

  • Bin...
  • Taken for 1 to 2 years
  • March 19, 2024

"Nurtec was a lifesaver for me initially. Not only did it help treat my migraines, but it also decreased the overall number I experienced. The effectiveness appears to have declined over time. I have continued to take it because it has decreased the severity of the headaches I experience on a daily basis, which has allowed me to work on most days. Unfortunately, I have noticed that my stomach was giving me more and more problems over the course of several months. Earlier today, I looked up potential side effects and realized that I experience all the G.I. problems described. As such, I will now discontinue this medication."

6 / 10
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11 Report
  • Nur...
  • August 15, 2021

"After 2 doses, started passing bright red blood in stool and gobs of mucus with stool. It has been 1 month and still dealing with reaction. Condition just now starting to get some better. Took Nurtec ODT 75 mg every 48 hours. Took 4 doses, then quit because of reaction."

1 / 10
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26 Report

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  • Stu...
  • Taken for less than 1 month
  • June 7, 2022

"I have had migraines since I can remember, from age 4 or 5 to now at almost 63. I have tried almost every migraine drug known and all the other things, like acupuncture, massage, diet, etc. I still have PTSD from receiving ergotamine infusions back in the early '90s and several other ridiculous drugs. The triptans are the only drugs that have ever helped, but they are not preventative, nor are they great as you age. Out of desperation, I decided to try Nurtec ODT as a preventative. First dose gave me a screamer of a headache. I thought I was having an aneurysm... seriously. Second dose and I realized my incredible and painful joint pain (have arthritis to begin with) and my black stool with mucus in it had to be from Nurtec. Needless to say, they are in the trash where 99% of the supposed 'miracle' drugs for migraines have ended up! What a horrible drug. Thankful I refused the Aimovig shots a prior neurologist tried to give me. Who knows how long they would stay in your system?? UGH!"

1 / 10
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  • Ros...
  • Taken for 1 to 6 months
  • August 5, 2023

"I have been taking Nurtec every other day for 1 month. It works fairly well, headache is mild. My issue is, I have no energy, depression has worsened, stomach pain, indigestion, and diarrhea, and joint pain. I am going back to using it only after I get the migraine. I may as well get the headache and feel better overall."

5 / 10
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More FAQ

  • Fin...
  • Taken for less than 1 month
  • October 22, 2022

"Originally, upon reading reviews here, I was hesitant to try this new medication. After years of triptan use and a continued increase in migraines per month, I ultimately decided that I had nothing to lose at this point. So, I took my first Nurtec two weeks ago and it turned out really well for me. I take it as a preventative every other day. I’ve not had a single migraine since the first dose. It feels like a miracle. I’m pleasantly surprised by the outcome. That being said, I did have stomach pain for the first few days. It eventually subsided as my body adjusted. Thankfully, I’ve yet to experience any further side effects, and I’m sensitive to medications. This whole experience has been positively surprising. I will convey that triptans caused numerous awful side effects for me: chest pain, muscle tightness, restlessness, anxiety, difficulty breathing, and eventually rebound migraines. I couldn’t take them anymore. Nurtec is far better!"

10 / 10
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  • Mr ...
  • Taken for less than 1 month
  • July 26, 2021

"I have chronic atypical/complex migraine. I used to be on Ajovy and Emgality, which both helped until my body learned to attack the monoclonal antibodies. Since those both work on CGRP, I was hopeful when I heard that Nurtec did, too. The first dose was nothing short of magical. I felt better than I had in years. The second dose actually made me feel worse, strangely enough. By then, though, I realized that I was horribly allergic to it. (A week later, I still have a rash.) Three days after stopping it, I got hit with the worst rebound migraine of my life. It felt like my body had sharp pains from head to toe, and my fever spiked to 102.3. Holy cow. So, word of warning: this might have a heck of a rebound for you."

5 / 10
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20 Report
  • Cha...
  • Taken for 1 to 6 months
  • October 6, 2021

"Have had migraines with aura for 20 years, about 4-5/month. For the last 5 years, I have been taking topiramate daily to prevent the pain, but I still get the auras. My doctor added Nurtec last month, and it has been amazing for me. I take it every other day, preventively. Since I started taking it a month ago, ZERO auras for the first time in 20 years."

10 / 10
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19 Report
  • Sus...
  • Taken for 1 to 6 months
  • October 25, 2024

"My neurologist prescribed Nurtec as a migraine preventative. I took it every other day for nearly a month. I noticed a few side effects, but at the time I just chalked them up to coincidence. First of all, after eating even a little bit, my stomach felt as if I'd eaten a huge meal. The food didn't seem to move from my stomach. It just sat there, causing me pain. Second, my body began to ache all over. My joints--wrists, shoulders, hips, knees, ankles--all hurt. Third, I woke up one morning with the worst acid reflux I'd ever had. It felt like someone had poured gasoline down my throat and lit a match. I did some research online and found out all of these are possible side effects from Nurtec. Yikes! I quit taking it immediately, but I'm still having the horrible joint pain. I'm hoping that goes away soon. I also started taking acid reflux medication (pantoprazole) and hope my reflux will soon go away. The sad irony is that Nurtec did help my migraines. But it's just not worth it."

1 / 10
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  • cam...
  • January 29, 2022

"At first, I thought this was a miracle drug. I had zero problems and interactions. I have terrible migraines, and this made them go away immediately and kept them away. However, after about three weeks of taking it every other day, I started having horrible heartburn. Or at least I think it was heartburn. My chest was tight, and I felt just generally awful. I thought maybe I got a cold or something, so I stopped taking it for a week just to make sure that wasn't what was causing it. I got better. And then I started taking it again a few days later, and I have the same symptoms again. Again, I'm not sure if it's just pain or indigestion, so I'm going to go talk to my doctor next week. I'm just testing this here to see if anyone else is having that sort of chest pain. It feels somewhat similar to Imitrex."

5 / 10
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  • Sar...
  • Taken for 6 months to 1 year
  • July 21, 2021

"I’ve been taking Nurtec for a little more than a year, and I’ll never go back to sumatriptan. I’ve been able to cut back on several medications and also happy that this one doesn’t cause rebound like my other meds did. I’m so thankful for this medication and how it has changed my life! I’m also thankful that my insurance covers it, and it’s FREE!!!"

10 / 10
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20 Report
  • Rob...
  • Taken for less than 1 month
  • August 3, 2022

"Within a few doses (was taking it every other day) caused brain fog, dizziness, nausea, and felt a tightness in my head. While it did stop a migraine in about 1 1/2 hours, I only started it on 7/20/2022. At the doctor's suggestion, I tried again, and on Monday, 8/01/2022, I had worse of the same symptoms. Have not and will not take another dose, but it is now Wednesday, 8/03/2022, and I still feel not just the brain fog but the tightness in my head and feel like I'm on sleeping pills. Left another message for the doctor. I WILL NOT take this medication again. Causing more health issues than just having migraines."

1 / 10
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  • Ama...
  • Taken for 6 months to 1 year
  • October 20, 2022

"I can finally find live my life now! I have suffered with migraines as long as I can remember. Debilitating migraines 2-3 times a week that can last for days. I canceled so many plans over the years and missed out with family and friends since the only relief was to try to sleep it off in a dark, quiet room. A large chunk of my PTO went to sleeping it off and having to miss work. It's impossible to work or function when your brain feels like it's exploding. I've tried so many things that didn't work or made it worse: topiramate, amitriptyline, migranol, IV treatments, allergic to triptans, bad reaction to Aimovig, etc. I've taken Nurtec for 6 months now as a preventative, and it is the only medication that has worked for me in a major way. Went from 2-3 migraines a week to now maybe 1 a month. And the few are so much more milder and aren't stopping me like they used to. No side effects. Thankful for the $0 copay, but I'm terrified once that is over. I can't afford 2k/month."

10 / 10
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  • Nau...
  • Taken for less than 1 month
  • March 24, 2023

"I had terrible nausea with this medication. It lasted all day, every day, and I was unable to do anything due to the extreme nausea. I rarely went to work. Nothing helped. Without medications, I have migraines every day. This medication did not take the migraines away. I did not try it during a migraine, though. But it is definitely not a preventative medication for people with chronic, everyday migraines. When I took the pill, within an hour, I was afraid that I was having a heart attack. It felt like an elephant was sitting on my chest for about one hour. I continued to take this medication for about 10 days, hoping that these reactions would go away after I got used to the medication. I finally had to stop taking it. It took about one month for the side effects to go away. It was miserable! And unfortunately, it never helped with my migraines. However, we all know that as a migraine sufferer, one will try anything to make the pain stop."

1 / 10
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10 Report
  • Dee...
  • Taken for 1 to 6 months
  • December 24, 2021

"This medicine has been AMAZING. Stopped the pain within 30 min every time. I will say I take it early on, so I'm not sure how it works if you wait till you're in the throes of a massive migraine before you take it. The taste is actually pleasant, like a mint. A downside is how UNBELIEVABLY expensive it is. Insurance is difficult to cover it unless you have a valid and documented reason for not taking the much cheaper triptans (Imitrex, etc.). Fortunately, I've been seeing a cardiologist and have had tons of tests proving the triptans are a bit dangerous for me, so my insurance pays 100%. Last week, the pharmacist told me the current out-of-pocket cost for 8 Nurtec pills was $1,036.00. It's insane, but it DOES work. Also, I had zero side effects and amazing relief."

10 / 10
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13 Report
  • 0 s...
  • Taken for 1 to 6 months
  • July 30, 2022

"Horrible! Prescribed as prevention, and the doctor told me this was sublingual, so I thought it would work faster. It took 6 hours to even feel any relief with my first dose, and that was only after 3 Excedrin! The migraine came back worse the next morning, and I had to wait to take my next dose! Read the fine print, and it is not sublingual… it’s orally dissolving and is not the same. The taste and texture are the worst when you’re sensitized and having a migraine. Plus, it has sucralose- a known migraine trigger… why would the company add that?? Never taking this again, and wouldn’t trust anyone I loved to take it either. Doesn’t work for getting rid of my migraines. Tried to take it without a day for a month and didn’t do anything in preventing them. Still dealing with 2-3 a week. 0 stars if I could!!!"

1 / 10
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  • AJD...
  • Taken for 2 to 5 years
  • October 22, 2024

"I’ve had migraines since I was a kid. They’ve continued to worsen with age. Most months, I was experiencing 23-25 days with severe migraine with aura, light sensitivity, nausea, aching body, stomach upset, sensitivity to smell and sound, dizziness, numbness in my face, and horrific stabbing pain on the left side of my head. I tried everything, including chiropractic treatment, antidepressants, exercise, topiramate, ice, hormones, magnesium, B vitamins, etc. Nurtec as a preventative has been a godsend. It gave me my life back. Now I just have to fight with insurance every so often to keep it. I have maybe two migraines a month now, and they’re nothing at all like they were. So thankful."

10 / 10
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  • Cla...
  • Taken for 1 to 6 months
  • September 6, 2023

"I have been taking Nurtec for about 9 weeks, and it has helped significantly with eliminating my migraines. By taking Nurtec every other day, I am able to have a better quality of life. I had been taking Imitrex half to a full tablet every day for the past 5 years, which has made my diverticulitis, ulcers, and inflammation in my stomach and bowels worse. Nurtec has improved my gastrointestinal health overall compared to sumatriptan. I am now fasting, eating light meals and salads every day, and both migraines and stomach problems are disappearing. Inflammation in my body is reduced. I also take 200 mg of CoQ10 and have eliminated taking my 10 mg of atorvastatin. I also take vitamins A, D3, B12, B6, and Lutein."

10 / 10
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  • Mis...
  • Taken for 1 to 2 years
  • July 15, 2024

"I have had cluster migraine with aura for years. Nothing I was given helped. I tried triptans, Ubrelvy, and a list of other medications. I started taking Nurtec for prevention. I have had nothing but positive effects, very few migraines in a year. I actually recently asked to try Ubrelvy, and the side effects were horrible. My neurologist put me back on Nurtec."

9 / 10
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  • Mat...
  • Taken for 6 months to 1 year
  • July 27, 2022

"This is the only thing that has slowed down and stopped many of my migraines. Have had them for 25 years following 7 months of birth control pills. Take it once every other day, dissolve under my tongue. Since I had serious allergic reactions to ibuprofen, Zomig, Imitrex, Ajovy shots, and Botox, I was scared to try this, but couldn't handle the side effects of the Botox anymore. Chronic fatigue is no way to live with your head still hurting. Been on it since September 2021. With my IBS, tummy issues were expected, so I always take it with food. Have had no side effects that noticeably pointed to Nurtec. Getting better, was able to start walking this summer, up to 3 miles. Migraines have changed, so can have painless ones, but they still stop. No complaints after going over a year with a non-stop migraine. Still have the menstrual migraine ones periodically that don't stop and last for days, but in my early 50s so hormones are going to be crazy."

8 / 10
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  • Its...
  • Taken for less than 1 month
  • October 17, 2021

"I started taking Nurtec ODT at the beginning of September 2021 for weekly migraines that showed up twice or three times a month. After using sumatriptan for a few months with dwindling results, I decided to give Cove a try in helping with a better prescription. From my choices, I decided to try Nurtec, and after its short-term usage, I could tell the difference between with it and without it. My migraines dropped in number (from 14-21 days to 4-7 days), and those that I would have were rather short, only lasting for hours instead of days. The only reason I was able to receive Nurtec is that I was still on an insurance plan with my mom, but after she lost her job and I found my own insurance, I have been denied access to it due to its high price. After doing research, I found out that one 8-pack costs over $2,000! Not being able to afford it, I’m currently in the middle of deciding on new medication to take without so many side effects. There is no reason for this medicine to cost so much."

5 / 10
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  • Hop...
  • Taken for 6 months to 1 year
  • April 30, 2023

"I'm back to update!! (I'm unable to edit my original review.) I was the 62-year-old who had suffered from migraines for 40 years and posted in November 2022 that I had not had a headache since the 15th. It's now April 2023, and I'm thrilled to report that I did not have a single headache day in March! I did have one in April after a very long flight and 90 minutes of driving a rental car through Atlanta, but that was it. I'm ecstatic! Although Nurtec ODT causes some joint pain, it's much more bearable than migraines, so I'm not complaining. I appreciate the fact that it's free of cost. Thank you, Nurtec ODT."

10 / 10
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  • JEM...
  • Taken for 1 to 6 months
  • September 10, 2022

"I have had chronic migraines for over 40 years and have been to numerous neurologists and taken many different medications and treatments, conventional and alternative, to prevent my migraines. Nothing worked until Nurtec! It's a godsend for me! It has nearly eliminated my migraines. The price of Nurtec needs to come down so it is affordable for everyone in need of the medication."

10 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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