Riluzole User Reviews & Ratings

Brand names: Rilutek, Exservan, Tiglutik

Riluzole has an average rating of 7.5 out of 10 from a total of 9 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 13% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Amyotrophic Lateral Sclerosis	6.5	5 reviews for Amyotrophic Lateral Sclerosis	7 medications
Obsessive Compulsive Disorder Off-label	8.5	4 reviews for Obsessive Compulsive Disorder	9 medications

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Jan...
October 16, 2020

For Obsessive Compulsive Disorder "Completely changed my life. No more OCD, no depression, no social anxiety, GAD, panic attacks, obsessive thinking, intrusive thoughts, no more phobias. It's like everything changed overnight, literally, and my life is finally worth living!"

10 / 10

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60 Report

AJs...
January 20, 2012

Rilutek (riluzole) for Obsessive Compulsive Disorder "My son, now 19, started riluzole as part of a small double-blind NIH trial 2 years ago. He has Autism, OCD, mood disorder, tics, and ADHD. This medication is extremely helpful in easing the overwhelming obsessive thoughts and compulsions that interfere with his ability to function. No side effects. I fight to renew insurance coverage each year for this off-label use and twice he ran out of this medicine temporarily, and we immediately noticed a change in his behavior. He is off antidepressants and ADHD medicines (Zoloft & Concerta) and is now on lamotrigine for tics and mood stabilization. A great combination. His functional ability assessments (IQ) went from mild retardation into a 'normal' range. His communication skills improved dramatically."

9 / 10

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73 Report

Jen...
Taken for 1 to 6 months
January 30, 2025

For Amyotrophic Lateral Sclerosis "I was diagnosed with ALS on 7/30/2024. I have mild symptoms that started in my right hand. I started this medication 9/2024. Two days ago, 1/28/2025, I adjusted the time of day that I take this medication, and I should not have done that. The muscle spasms and weakness in my hands and arms persisted like nothing I have felt before. It was horrible, and I know that this will come later, but if this medication delays it, I am all for it. After two days, I went right back to my normal schedule, 12 hours apart with no food for two hours before and one hour after (so the meds can get into my bloodstream). About a day later, I am back to where I was, thank goodness! The spasms are there along with the weakness, but not nearly as bad. I have not experienced any negative side effects at all. I do take this medication along with 1/2 of a muscle relaxer and also the vitamin alpha-lipoic acid. I am a 57 y/o female with no other health conditions. I hope this helps my extended ALS family out there!"

10 / 10

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1 Report

Frequently asked questions

What is the difference between Rilutek, Tiglutik and Exservan?

Ano...
Taken for 1 to 6 months
October 25, 2021

For Amyotrophic Lateral Sclerosis "I think this drug is dangerous and shouldn't be prescribed. I believe this ended the life of the father of a friend of mine. Common side effects include respiratory problems. Taking this drug can temporarily lower the white blood cell count. I'm sure this comment will be deleted also, which says it all really. Please take caution if you or somebody you know are taking this drug."

1 / 10

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14 Report

BPD...
February 8, 2012

For Obsessive Compulsive Disorder "I have not been on the medicine for long enough to truly know what kind of difference it is going to make in my life. So far, I am almost completely pleased with the results. One of the major consequences of my particular type of OCD is isolation and avoidance. On Rilutek, I'm more willing to confront my fears, phobias, and triggers, and generally, I seem to be less stressed in those situations. My mind also seems to work better in that the thing I'm afraid of does not seem so real. Rilutek is an add-on to my other prescription medicines. In the last year, I have made more progress with medication than I have in the previous four together."

8 / 10

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37 Report

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Pam...
Taken for less than 1 month
May 13, 2014

For Amyotrophic Lateral Sclerosis "We have noticed that when our mom decided to stop taking this medicine, she became weak and tired. She has only been taking it for 3 weeks. Was told she has amyotrophic lateral sclerosis in March 2014. Wish we didn't have to jump over so many walls to get answers. Got to love Medicare!"

6 / 10

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21 Report

Naz...
August 10, 2022

For Amyotrophic Lateral Sclerosis "My husband has been taking this drug since August 2021 and has continued taking it without missing any doses. We set the time (7:00 a.m. & 7:00 p.m.) to take riluzole in time without missing. After taking this drug, it seems to delay the decrease of deterioration. But I don't know what will happen in the future. -10.08.2022"

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5 Report

ocd...
February 13, 2013

For Obsessive Compulsive Disorder "This medicine really helps."

7 / 10

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20 Report

Jen...
January 6, 2021

For Amyotrophic Lateral Sclerosis "My mom's experience is the same as above. She went off it for a few days, and we could see the decline."

9 / 10

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3 Report

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