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Seroquel XR for Depression User Reviews (Page 2)

Reviews for Seroquel XR

Commonly mentioned side effects
  • Mik...
  • November 28, 2014

"I was prescribed Seroquel 100 mg for Post-Traumatic Stress Disorder, and I could only take it for two days. I took it as prescribed before bedtime. I almost crashed my truck several times on my way to work, and I had to pull over on the shoulder to sleep on my way home from work. Day 2 was a Saturday. I slept for 14.5 hours. I can't function at all on this."

6 / 10
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72 Report
  • Emm...
  • Taken for 1 to 2 years
  • April 30, 2013

"I was put on 25 mg of Seroquel at age 15 due to major depression. I agree with the previous comment made, even on such a low dose, I also feel I'm in a chemical straightjacket. I have trouble thinking straight, I can't concentrate for over 15 minutes, my sleep is average - it's extremely hard to wake up. I also find I'm so much angrier and impulsive, I stutter and can't form words, as well as shaking uncontrollably in my legs when I get anxious. I also get headaches at least twice per week. However, my family and close friends have noticed a considerable improvement in my mental health, e.g., suicidal thoughts have almost stopped completely, and an increase in more 'happy Emma days.' Such a strong, powerful, and dangerous med."

7 / 10
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51 Report
  • Ind...
  • Taken for 1 to 2 years
  • September 25, 2013

"I have been on 400 mg of Seroquel XR along with my antidepressant for more than 1 year. Initially, the medicine worked great for my stress, delusions, and helped me sleep well at night. Lately, the anxiety has returned, and I have severe anxiety during the daytime. At night, I pass out, so I don't feel much. However, this medicine has caused me to gain a lot of weight. I would say I have gained about 25 pounds since starting the medicine."

8 / 10
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53 Report

Frequently asked questions

  • Tom...
  • Taken for 2 to 5 years
  • January 29, 2018

"First, I'm not schizophrenic, nor have I been diagnosed as bipolar. I take this for drug-induced anxiety. I was initially given Seroquel XR because I exhibited rapid speech and a disorganized thought pattern during my continual intoxication by kratom. Kratom is a 'natural,' legal substance with opioid and stimulant qualities. Well, I noticed right off that Seroquel XR calmed my racing thoughts. I saw this as a benefit, but the next move was for me to quit using kratom. I got help for that via SUBOXONE, which I'm still on. My whole life and way of thinking took a sharp turn for the better. I remain on the Seroquel XR, along with the SUBOXONE. When I questioned the continued need for Seroquel XR, my doctor simply said, 'Look, you're doing great. Why change a thing?' And he's right. So Seroquel XR remains a part of my daily recipe for success."

9 / 10
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30 Report
  • sic...
  • Taken for 1 to 6 months
  • August 26, 2015

"Hate this med. Constantly sick on it. Stomach pain, severe diarrhea, passing out, severe dizziness, and unable to wake up. Hungry for food all the time. Nasty taste in mouth. Thirsty all the time. Can't motivate myself to do anything. This was on the lowest dose available. Won't take it ever again, don't care what my doctor says. No way."

1 / 10
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41 Report

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  • Ale...
  • November 6, 2017

"I've been on this for 4-5 years, and it is my rock. It literally helps me so much, I couldn't have made it through high school without it. Honestly, it's what helped me through my suicidal phases. I still get them, but it's not as intense, and I don't try to act on it anymore."

10 / 10
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  • 55 ...
  • October 17, 2009

"It seems to be very helpful for my depression, anxiety, adult ADD, and overall mood. Seroquel XR also seems to have no noticeable side effects, and I sleep great. I've been taking 2 of the 300 mg, in the evening, now for 2 months."

9 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • March 30, 2016

"It was mainly prescribed as a sleep aid, in addition to its antidepressant qualities. I was on regular Seroquel and now on XL as I have trouble staying asleep. It's slightly better. I'm getting 6 hours of sleep a night. I am not usually groggy or snowed by this, maybe once per 30 doses. I'm okay with it. Only downside is cost (XL is brand)."

8 / 10
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29 Report
  • Ang...
  • April 11, 2012

"Was taken off Geodon because of nighttime anxiety and put on Seroquel XR. I feel so unmotivated. Sedated. I no longer feel better by afternoon when it's time to take it again. I dread the next dose. Haven't felt this depressed in a while."

1 / 10
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  • Arr...
  • Taken for 1 to 6 months
  • November 11, 2015

"My experience on Seroquel nearly cost me my job as it turned me into a zombie! Since going off the drug, I am fully functional. My head is clear and I have energy to do things. I cannot believe my doctor prescribed me an antipsychotic drug such as Seroquel. Colleagues observing me thought I had undergone a major personality disorder. I have been off it for a month now and not missing it one bit."

1 / 10
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  • Dan...
  • Taken for 6 months to 1 year
  • July 17, 2021

"I have been on the Seroquel XR 50 mgs, and it absolutely works better than anything I have ever taken for anxiety. And I've taken every SSRI under the sun, Valium, clonidine, gabapentin, and Vistaril all in the past. This medication is a lifesaver. It does make me feel drowsy 3-4 hours after taking it, so it should be taken around dinner time. My doc first started me on it first thing in the morning, and I was dozing off by noon. But other than that, it has been a lifesaver. Almost no anxiety, I sleep better, my appetite is good, my mood is good and confident. For me, it even helps to relax my muscles. I'm so glad my doc took a chance and prescribed this medication off-label for my anxiety. It has given me a new lease on life."

10 / 10
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  • Anonymous
  • April 10, 2009

"I was put on this medicine very aggressively (200 mg, quickly upped to 400 mg) after a suicide attempt. As an antidepressant, it is more effective than the first-line medications like citalopram. It will help with sleep and a lack of hunger. However, I absolutely hate the side effects. It is often said that antipsychotics 'steal your soul' or act like a 'mental prison.' I would have to agree. To begin with, this was fine, with severe depression, I was happy to take any way out. However, after about 6 months of this, I decided enough was enough. Now I'm off it, my personality is back."

6 / 10
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44 Report
  • Bue...
  • November 7, 2011

"The first night I took this medication, I almost ran out of breath before climbing the stairs from the basement to my room (it's as if my respiratory system was somewhat repressed). It also caused some chest/heart pain. On the other hand, I slept well for those two nights. The side effects may be more dangerous than one's condition. Please be careful."

5 / 10
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39 Report
  • Gas...
  • Taken for 2 to 5 years
  • May 20, 2017

"I was on this medication for around 3 years at different doses, anywhere from 50 mg to 600 mg. It was a very good medicine and helped a lot with my anxiety and depression and really calmed me down and was very helpful, but the weight gain was a killer. I would try to go off over and over and would have to keep going back to it because I would be in such bad shape without it. I had a love/hate relationship with it. I became pre-diabetic while on it. I finally was able to go off and stay off at one point. It's a great drug, but the side effects are horrible as far as weight gain."

8 / 10
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23 Report
  • Mia...
  • Taken for 1 to 6 months
  • September 29, 2018

"I got prescribed Seroquel XR for my sleep, and it is supposed to help me with my sleeping, and it does. I don’t follow a specific roster of when I’m meant to take it, so I’m on and off every week, and I only just started noticing that when I start taking it after a while of not taking it, my depression gets worse. I’m not really sure of what’s going on."

3 / 10
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29 Report
  • Anonymous
  • September 18, 2011

"Seroquel XR is very good. It boosts up my energy. After trying other medications, this is the best, with little side effects. In the morning, you feel like staying in bed and weight gain because of hunger cravings."

9 / 10
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31 Report
  • Ama...
  • July 23, 2015

"In the beginning, I was on 300 mg of Seroquel (not extended release) for 3 years. Got pregnant, they took me off. I moved provinces, they ended up putting me back on a smaller dose, 150 mg. Sleeping-wise, I would go to sleep right away and stay asleep all night. For the past 2 months, they decided to put me on 150 mg Seroquel XL. Now it takes me hours to fall asleep, and I wake up constantly throughout the night and have a hard time falling back asleep! I feel like XL does not work near as good, depression-wise and sleeping-wise."

3 / 10
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  • Jam...
  • January 16, 2021

"This medication, Seroquel XR, caused me to have body chills and hungover fatigue. I couldn't do anything after taking 3 pills, it hit me like a ton of bricks. I was totally hungover for 2 days, bad headaches, and I was shaking nonstop. I've stopped this medication, can't do it again."

1 / 10
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  • Mik...
  • Taken for 1 to 6 months
  • March 9, 2018

"It is okay for me, I can't say it helps that I can notice. I actually do not notice, but my doctor says I have improved a lot. I don't get any side effects anymore on 200 mg per night, it was okay for staying asleep too as I suffer massively broken sleep. It was no good for getting me to fall asleep. I rate it 5 since I personally see no improvement, but my doctor does."

5 / 10
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  • Fat...
  • Taken for 6 months to 1 year
  • May 4, 2022

"I have been on 200 mg of Seroquel XR for about 7 months. I am underweight, and it did not cause me weight gain. It has been working miracles for my mental health, but I just started tapering because the side effects are sometimes excruciating. After half an hour of taking the med, I can’t walk or talk. I can hardly breathe, and the RLS is terrible sometimes. But those side effects only last 2 hours after taking the med. I am also stopping it because I have been feeling great, and I don’t think I need it anymore. (I’ve had depression with psychotic features and used to frequently experience depersonalization, derealization, and some delusional thoughts, disorganized thinking). All of which decreased in intensity rapidly after starting Seroquel. Generally, it was a good experience for the most part. It really helped with my memory and information processing."

8 / 10
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  • ssr...
  • August 18, 2010

"Was put on this medication for mood stabilization as well as for sleep. At the lowest dose, it made me excessively drowsy the next day. As for the mood stabilization, all it did there was make me have violent outbursts while on the medication."

1 / 10
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22 Report
  • No ...
  • Taken for 1 to 6 months
  • December 1, 2021

"On this for depression & bipolar. Terrible word blockage. Would experience electrical-like zaps in my brain. Felt like a zombie, unable to focus, no energy to do anything. Slept for 16+ hours every single time I took it."

1 / 10
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  • Wha...
  • March 22, 2010

"It helps. Will make you feel better about yourself."

10 / 10
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49 Report
  • Nis...
  • Taken for 10 years or more
  • October 26, 2019

"All it does for me is help me sleep. I'm addicted to it now! Can't sleep without it. And it costs $100.00 a month! I wouldn't recommend it to anyone!"

7 / 10
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20 Report
  • ang...
  • December 16, 2012

"Quetiapine 25 mg used to get over post-traumatic stress disorder post mental health problems caused by an allergy to Valium. Presently taking 50% of a tablet at night."

10 / 10
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32 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.