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Seroquel for Bipolar Disorder User Reviews (Page 4)

Seroquel has an average rating of 6.8 out of 10 from a total of 373 reviews for the treatment of Bipolar Disorder. 58% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Seroquel

  • Macca...
  • January 8, 2014

"I take Seroquel for bipolar, I had side effects when first taking it such as couldn't wake in the morning and sluggish, it took me a couple of months to get used to it, now I take it at about 10.30pm asleep within 20 mins and up at about 8.30 am, well rested, it has been great for my mania, which can last weeks at a time. I feel so normal again, I take 100mg a night with 600mg of Tegrotol you just have to give it time to do it's thing, the side effects go away. I have no weight gain at all on Tegrotol, it's the opposite, I'm losing weight."

9 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • March 27, 2019

"Seroquel has been a life-changer for me. It has curtailed my manic episodes and kept me sane as I struggle with bipolar I with paranoid features. I recently attempted to switch to Geodon due to weight gain, but I immediately switched back to Seroquel because the benefits outweigh the risks of some mild weight gain. I take 400mg daily: 200 mg in the morning and 200 mg in the evening. It helps me get a decent night’s sleep which is crucial for keeping me from slipping into bipolar episodes. I give it a 9/10 because the weight gain can be a moderate annoyance."

9 / 10
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  • Romanee
  • Taken for 1 to 2 years
  • November 5, 2012

"After later years of my adolescence and early adulthood I was finally diagnosed (bipolar) and prescribed Seroquel along with lithium. Not only did I finally feel a sense of peace within myself I found that I no longer engaged in the reckless activity that I seemed to have no control over. This behaviour which caused so much grief and upset, nearly caused the breakdown between my family and which I nearly destroyed myself. It does not get rid of my depression completely but they are not as bad and I find I can cope where as in the past I couldn't. I find that it's best to take it before bed as it makes me very drowsy which I find a good thing because in the past I found it very difficult to sleep. Hope this helps."

10 / 10
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58 Report

Frequently asked questions

  • JaxWebb
  • Taken for 1 to 6 months
  • February 1, 2016

"I was on this med in 2010 for a year. The dose went from 25mg up to 400mg. The first few weeks were very difficult. It knocked me out cold and I had such a blocked nose I could hardly breathe. I toughed it out and my depression lifted. I stopped taking it because of really bad blocked nose. I have just had a major depressive episode (2015) with insomnia. I was prescribed 100mg. It worked within 24 hours. I was able to sleep for 9 hours and feel refreshed and energized. The depression and anxiety have improved dramatically. This time I'll stay on Seroquel."

10 / 10
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  • Blueb...
  • Taken for 1 to 6 months
  • November 15, 2012

"Seroquel makes me feel like I'm on a level playing field again. I don't feel like my thinking's distorted and I don't cry uncontrollably like I have all of my life. I have gained weight but I'm fixing to start taking Topamax to counteract that. If the Topamax doesn't work I will still continue to take Seroquel. I rather gain weight and be able to cope with life 100% better than I did before."

10 / 10
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Are you taking this medicine?

  • JLD
  • Taken for 1 to 2 years
  • February 2, 2024

"I started Quetiapine approximately one week before my first semester of Finals at law school during my third year. The reason I first began Quetiapine was for mood stability purposes; I had tried many other second-gen antipsychotics with the goal of finding one that helped me to stop a single bad thought from spiraling into an all-consuming depression that would ruin my day or week. Quetiapine has been successful at doing just that. Most vividly, I recall taking the drug during a week in which I had 4 law school finals in one week and the work/studying felt insurmountable. Without making me too tired to complete the work, I remember my mindset quickly turning to “Even if the work is insurmountable, I don’t care, I’ll be fine.” The stability Quetiapine has helped me find in regard to mood has been incomparable to other drugs in the best way. I too experienced the side effect of weight gain. I believe one can avoid that by simply making an effort to be active. I recommend this drug."

7 / 10
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  • Dirty...
  • Taken for 1 to 6 months
  • March 11, 2013

"I had great success at doses of 200-400mg. Anything above that and I black out an hour after taking it. I found out later I had been writing belligerent texts, yelling at my children, and verbally abusing my wife. Im going to ask for 300mg since it helped my insomnia, and made me content and happy the next day. All without the horrible side effects listed above. I have tried Geodon, it gave me severe tachycardia, and yet made me too tired to function. A horrible inescapable feeling as the tachycardia made sleep impossible. Zyprexa just made me fat and gave me restless legs so bad I couldn't sleep. Seroquel is best by far, but have your loved ones monitor you."

8 / 10
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  • justR...
  • Taken for 6 months to 1 year
  • September 24, 2012

"I was diagnosed with BiPolar Disorder 1 about 8 months ago. My doctor put me on Seroquel 100mg. I do have to take it at night due to the drowsiness it causes. It has made a dramatic change in the racing thoughts and negative self-image I felt. I've also had a marked change in my insomnia. I was misdiagnosed for a number of years, and couldn't understand why the other meds didn't make a difference. I wake up feeling rested. I did have some vivid dreams when I first began taking it. I also get the munchies, but they have subsided considerably in the last month or two, and have dropped almost 20 pounds. This is magical as far as I'm concerned! As well as the Seroquel, I also take 20 mg of Lexapro and 600 mg of Neurontin every night. Thanks!!"

9 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • February 23, 2019

"I’ve had many problems with the wrong medications making me more unstable including restlessness. My seroquel dose was raised very quickly to 250mg in hospital, then overmedicated after. But now after working with a doctor for a long time my doses are between 75-125mg and have been life saving to calm me down and help me sleep and think clear after having very bad insomnia caused by anxiety. Ignorant doctors call this a sleep dose but it has many mood stabilizing benefits for people sensitive to medications. I also take with lamictal in morning and Gabapentin at night Klonopin as needed has been life saving."

10 / 10
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  • Muffin...
  • Taken for 1 to 6 months
  • October 18, 2021

"This is horrible with extremely serious side effects. I got anxiety, shaking, face twitching and stuttering like never before. I won’t ever take it again — you cannot pay me enough to get back on it!"

1 / 10
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  • october...
  • October 3, 2013

"I have been a bipolar as of 26 years. After my first and huge depression, I have not missed lithium not even for a day. I have had a really good acceptance to Seroquel, but not to Seroquel XR. The difference is huge, and XR plays with your sleep patterns and more. The insatiable hunger is so, so, true as is the weight gain. I just eat less and less and less and as a person who has had an amazing metabolism, still am 105lbs. After 3 children, my teen weight, I am now at 115lbs and I hate it. But I have no desire to stop Seroquel."

9 / 10
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  • thesk...
  • Taken for 6 months to 1 year
  • January 8, 2017

"I've been on this for about 8 months so far. I take 300mg at bed time. It helps with sleep, but I do feel a bit tired during the day. This has really reduced my mania. I used to argue with people until I was literally foaming at the mouth, but now I lose interest in arguments within 5 or 10 minutes. Twitter and news used to upset me and I'd get ampted up about stories, but that's gone away mostly. Now I can react to things that used to make me furious with a laugh or just a short discussion with someone. Seroquel's not perfect, but the weirdness and intensity I used to experience has gone. It also helps greatly with my IBSd. I haven't had any weight gain, but my diet is low-fat and limited. Seroquel is MUCH better than TCAs btw. Good luck!"

8 / 10
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  • HopeK
  • August 6, 2013

"I have tried just about every medicine there is to treat bipolar disorder, and Seroquel hands-down is the best one for me in terms of stability. However, the weight gain has been a problem. I gained 40 pounds on Seroquel. The good news is I've lost 16 pounds of that in 3 1/2 months. It's been hard work, but I am confident I can meet my goal of losing 48 more pounds over the next year."

9 / 10
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  • Anony...
  • Taken for 2 to 5 years
  • June 5, 2016

"Seroquel has been very helpful with sleep, and I also noticed some mood stabilization in combination with Lamictal and sometimes Klonopin. Sometimes it is overly sedating, but taking it a couple of hours before normally going to sleep is important for me so that I don't feel drowsy the next day. I did not notice any weight gain on it. My doctor started me on 50 mg, which was good for sedation, but no major difference in mood. 100 mg does make a difference in lower my anxiety and some mood stabilization with my other medications, but sometimes she recommends me to take 200 mg to reduce mania from flaring up when it starts. Overall, this med has been useful for Bipolar 1 for me."

8 / 10
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  • lalal...
  • Taken for 6 months to 1 year
  • February 7, 2022

"I once rated this medication highly for my initial positive experience with it. I now believe that is only because it helps me sleep. Once I got up to 200 mg, I felt like a zombie and experienced some other concerning symptoms. When I expressed my concerns I was told that this was a "baby dose" and they intended to still increase from there. I disagreed. I have weaned down to a sleeping aid dose and intend to decrease from there and get off this stuff. It's terribly addicting. When I was at 200 mg I used to experience withdrawal like symptoms if I was accidentally late to take my nightly dose, splitting headaches, shaking. I've seen some say it can be dangerous to not have an exact time each day it is taken, but this was never expressed to me by the psychiatrists who prescribed me. This is not an opiate, but there's a reason some people sell this and call it "baby heroin". If you get prescribed it for sleeping, it did help with that."

1 / 10
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  • 0rdin...
  • September 24, 2014

"Seroquel helped my paranoia and really kept me mentally stable, but I also was tired all the time, sometimes sleeping for 15 hours a day. I also gained 30 pounds within three months of being on Seroquel. I wouldn't recommend this medicine for anyone who does not wish to rapidly gain weight."

6 / 10
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  • BPb
  • January 3, 2020

"Seroquel did not feel like it was doing anything for me the first month and a half in terms of my mood because it was the only med I was on. It did help me sleep again -- but I can't say it saved me from all of the racing thoughts and rapid cycling when up. As someone with Bipolar Disorder who experiences severe depressive phases, two doses of Lithium Carbonate, Gabapentin as needed for anxiety, and Seroquel 150mg at night for sleep is what is best for me. I guess how it forces me to fall asleep and stay asleep is what in turn effects my mood to be more relaxed the next day. Who wouldn't be relaxed when they sleep 8-12 hours a night lol. Other than that effect I do not notice a big difference in my mood change like I do with other meds."

9 / 10
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  • GRano
  • Taken for 2 to 5 years
  • October 25, 2018

"I have been on Seroquel XR for 2.5 years now with doses ranging from 150mg to 250mg. Currently taking 200mg. It does work, BUT it works very slowly, therapeutically talking. The anti anxiety effects kick in I would in a week or two maximum and the sleepiness is very intense in the beginning. What I don’t like about it, is that you get used to the dose very quickly and the symptoms return needing to either up or lower the dose. It’s not a super stable medicine. The first days of upping the dose you do feel more stable, calmer, peaceful but a week after you find yourself asking for more. Now therapeutically, it brings you back to earth, you know, but it’s not enough. In my case the lack of motivation is a big thing for me. It was so bad my doctor thought I had attention issues and wanted me to try Adderall and I said no because I knew it was from seroquel. Anyway, all antipsychotics are motivation killers and make existing depression worse and trigger ADHD in my case. Good luck."

8 / 10
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  • Mymocha
  • Taken for 5 to 10 years
  • March 1, 2017

"I was having extreme depression and hypomania and they could not find the correct drug for me and this was the miracle drug for me it was the key. It works very well for me and I would recommend it. I take Seroquel at night because it does make me a little sleepy."

10 / 10
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  • JJJ
  • February 23, 2013

"I have found Seroquel to be very helpful in my life. I was on high antidepressant medicines but gave those up. The Seroquel helps me lead a normal life by allowing me to sleep and calm down after long working hours in a high demand job. I take 100mg before dinner which helps my appetite also. I would not take Seroquel during the day as I feel it would inhibit my ability to communicate at work. From what I've read some interpolate the effects of the medicines in differing ways but I can honestly say it has saved me from a very dark place. Expensive but worth the cost."

10 / 10
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  • MCarey
  • February 23, 2009

"A word to the wise: A psychiatrist prescribed a small dosage of Seroquel (at bedtime) for me (25 MG) to promote sleep. After a short period of time, I noticed an overwhelming craving for sugar--pastry, candy, milkshakes, etc. During proceeding visits to my family physician, I learned that my sugar levels were rising steadily, something uncommon in my previous medical history. Eventually this rise in blood levels developed into diabetes. Once this cause and effect was established, I ceased taking Seroquel. I no longer have an insatiable appetite for sweets."

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  • Kimbe...
  • August 8, 2013

"This medicine worked at first, but after taking it for a few (2) weeks, I developed anxiety & panic attacks. I've had panic attacks in the past but not like these. I wasn't afraid of anything specific; it was like a constant fear. Also, my heart would race so bad. I am being weaned off this & switching to Zyprexa."

1 / 10
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  • Rotti...
  • Taken for less than 1 month
  • August 6, 2019

"I tried this medication a few years ago and could never get the dose correct. It was either too much or not enough. I recently tried it again and only took it for a week before the doctor took me off. I was taking this medication for bipolar disorder and insomnia. 30 minutes to 1 hour after taking this medication I would have constant dry mouth and my legs would twitch, RLS. Constant tossing and turning because of my legs and having to drink water because of the dry mouth finally passing out hours later and feeling like rubbish the next day."

2 / 10
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  • Melyssy
  • Taken for 10 years or more
  • January 24, 2017

"I've been on Seroquel more years then I know.I have always been on the magical 200mg. I'm only on 50mg now, because of weight gain. I really did not want to be on this, and tried to go off..The headaches, and misery are just awful trying to come off this drug. So, back on Seroquel... along with Lamictal, Tegretol and Topomax. I have Bipolar 1, another name I've been told is Classic Bipolar. Seroquel helps with sleep for sure. Don't like the heaviness on the chest, if it's too high a dose. Also, getting up to eat like 10 minutes after taking it. AND feeling zombie next day. I've noticed if My meds aren't taken before midnight, forget the next day. Next day is gone..Sleeping all day. And If I don't snack with these meds,my heart feels weird."

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  • AnonA...
  • September 16, 2014

"Somewhat hit or miss on mania, racing thoughts and the like. Pretty effective as a sleep aid though. Currently taking 300mg as needed as it was mainly prescribed for sleep. It is as effective as benzodiazepines in that regard, without the benzo withdrawal. It does leave me feeling gritty and nasty the next morning though, but it's better than insomnia."

8 / 10
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43 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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