Skip to main content

Compazine for Anxiety User Reviews (Page 2)

Compazine has an average rating of 1.5 out of 10 from a total of 55 reviews for the treatment of Anxiety. 4% of reviewers reported a positive experience, while 93% reported a negative experience.

Reviews for Compazine

  • RNano
  • Taken for less than 1 month
  • November 4, 2019

"I’m sorry you all have gone through this but at least I feel I am not alone! I went to the ER last night for a severe migraine and they gave me toradol, Compazine and dexamethasone. The crawling out of my skin and restlessness, fidgeting constantly was the worse! It’s been 12 hours now, and seems slightly better, how long does it last? Hang in there my fellow suffers, try to remember it won’t last forever. XO"

2 / 10
Was this helpful?YesNo
15 Report
  • Marie
  • June 7, 2018

"About a year ago I went in to the ER for nausea and headaches they gave me Compazine through my IV almost instantly my heart was racing to the point I almost passed out I was screaming for help. How does one get over the fear of taking medicine once something like this has happened to them?"

1 / 10
Was this helpful?YesNo
18 Report
  • AmyNi...
  • Taken for less than 1 month
  • June 10, 2021

"Never EVER again. I had just gotten back to my inpatient room after having my KIDNEY removed. I was gutted like a fish and in a lot of pain. I was having some nausea due to surgery messing with my IBD. She put Compazine in my IV and I immediately sat up and screamed "What did you give me??" I was literally crawling out of my skin and started with this full body restless leg thing and could not stop moving. Which was horrible because I had JUST come out of surgery and had multiple abdominal incisions. It went on for hours, sleep was out of the question and they didn't bother to speak with the Pharmacy to see if there was something that could reverse it or alleviate the symptoms. The resident was like "Gee- Not sure what that's all about". I later told my PCP and she immediately listed it as an allergy in my chart. Never. Ever. Again."

1 / 10
Was this helpful?YesNo
8 Report
  • Asia
  • Taken for less than 1 month
  • April 10, 2019

"It’s so sad that these doctors don’t care about us like they should. I went to the ER today because I was having debilitating pressure in the middle of my head now I was already messed up when I got there, and I already suffer from severe anxiety and then they turned around and gave me Compazine in my IV. I literally I felt like I was dying, I could not be still, I could not sit down, I didn’t know what to do, my body almost couldn’t handle this medication and the reason for giving this was because I had a headache. No... people, please do not ever take this drug at all it dose not help you it hurts you. I’m still sleepy from taking this and it was 10am now it’s 9pm where I am. Do not take this drug,"

Was this helpful?YesNo
11 Report
  • I...
  • February 7, 2018

"I have a severe anxiety disorder I came in with chest pain and sharp pains in my head the doctor gave me compazine combined with Benadryl and I felt a absolutely horrible went into full on panic mode felt like I was having a tachycardia attack couldn’t speak had cotton mouth the whole 9 yards. What genius gave this to me knowing the side effects?"

1 / 10
Was this helpful?YesNo
12 Report

Are you taking this medicine?

  • MJano
  • Taken for less than 1 month
  • April 16, 2021

"Please BEWARE!!! All bad reviews about Compazine are true. I went to ER for dizziness and chest pains. The Dr. said she was going to give me something for anxiety. The nurse came in and gave me Compazine through IV she forced really fast so she could send me X-ray on my chest. She left out within a matter of seconds I felt a wave of heat in body. I started taking the IV out and blood pressure cuff off. I ran to the restroom looking for a window to jump out of a window. I started yelling calling the nurse and ask what did you do to me. I have never felt like this before in my life. She called Dr. they gave me Benadryl to try to reverse. 2 weeks later I was still experiencing extreme anxiety and never had anxiety before"

1 / 10
Was this helpful?YesNo
7 Report
  • Jcano
  • August 21, 2019

"I really wish I would of read these comments before I given compazine through an IV. Only let them give me half the dose after I started feeling like I was going to pass out. Worst experience of my life. My heart rate was 174 for hours and I couldn't stop pacing back and forth for hours. Anxiety at its very worse. I honestly though I was going to black out constantly and also felt like I was going to rip my IV out of my arm take my clothes off and just run. I wish this drug up on no one. The hospital should be sued for giving this drug to patients. Stay away...... I pray no one else goes through this. Its been 30 hrs and I do fell better than I did but I still feel a bit jumpy and not myself....."

1 / 10
Was this helpful?YesNo
9 Report
  • Manda
  • September 17, 2019

"I was given Compazine about 3 weeks ago most horrible experience of my life I tried to pull out my IV I felt like I was literally going to die and now thanks to this medication I suffer from PTSD because it was so traumatic I have constant panic attacks Compazine has ruined my life"

1 / 10
Was this helpful?YesNo
9 Report
  • Bri
  • Taken for less than 1 month
  • June 15, 2020

"I ate some edibles that apparently had 300 mg of THC (yeah terrible) I had a bad trip from it and suffered from an anxiety attack. The rest of that week I was sleep deprived and had tremors, also my head was hurting but it felt like it was in my brain. I went to the ER and they gave me the headache cocktail with Topane and Benadryl. That entire day was bad, I wanting to scratch through a wall and scratch off my face. I couldn't sit still without feeling all kinds of weird nerves throughout my body. It has been 3 days and I feel like myself somewhat now. However, I have this weird tingling sensation in my brain whenever I fall asleep or wake up. 1/10 would not recommend. And yes, I also suffered anxiety.. I couldn't drive for the first 3 days without being scared nor could I sleep alone or even be alone."

Was this helpful?YesNo
7 Report
  • James
  • Taken for less than 1 month
  • November 17, 2019

"I was given compazine this while in the ER for my appendix. I was still nauseous, and couldn’t have zofran yet, so they started this. This drug made me CRAWL out of my skin. One of the worst feelings I have ever had."

1 / 10
Was this helpful?YesNo
7 Report
  • Anonymous
  • Taken for less than 1 month
  • April 2, 2021

"I went to the emergency room for a migraine that had lasted three days. The NP gave me compazine and Benedryl via IV. Once she pushed it I immediately felt like I was about to die. I didn’t feel like myself and literally begged them to discharge me. It was the worst feeling I ever had in my entire life. It has me feeling like I was dying a slow death and it took a day for the side effects to finally go away. This drug is dangerous and I don’t recommend to anyone who already suffers from panic attacks"

1 / 10
Was this helpful?YesNo
5 Report
  • Compa...
  • Taken for less than 1 month
  • November 2, 2021

"I went to the ER for a migraine and they gave me this through my IV…I almost lost my mind. Everything was aggravating me. My heart felt like it was racing, I felt like I wanted to get up and run for miles. This had to be one of the most scariest moments of my life. This drug makes you feel like you’re gonna die - there I said it."

1 / 10
Was this helpful?YesNo
4 Report
  • Anonymous
  • August 6, 2021

"I went to ER yesterday for a migraine. Was given compazine. It gave me the worst panic attack of my life. I couldn’t stop moving. I felt like I needed to tear the skin off my body. I was screaming. I wanted to rip out my IV & blood pressure cuff. Struggling to maintain control of my body/thoughts, I lied and told them the headache was gone and to discharge me immediately or I would leave on my own. Told nurse I wasn’t ok. She said “the compazine does that sometimes, but it will pass”. It didn’t pass. It hasn’t passed. I have never felt so uncomfortable. Today, I feel like my skin is crawling. I can’t sit still, can’t sleep, lay down. I can’t focus, and every part of my body just feels off. I’ve been desperately calling any medical professional I can think of to get help/relief. I refuse to go back to the ER. I would take a severe migraine any day over how I’m feeling right now. I already suffer from depression and anxiety, and this has thrown me into a tailspin."

1 / 10
Was this helpful?YesNo
4 Report
  • Mel
  • Taken for less than 1 month
  • September 13, 2019

"Went to ER for a migraine and was given compazine in IV. Within a couple of minutes I wanted to crawl out of my skin. I literally was ready to rip my IV out. My husband went and got the nurse. I told her to get my IV out and I didn’t care what she had to do but I was leaving. She acted like I was a nut job but went and got the dr. He instantly knew what it was. He said, oh I’ve seen people run out of here on this stuff. Then why would you give it to anyone??? He gave me a big dose of Benadryl and it did help but I had to walk for hours. Strangely Raglan does the same thing to me. I’ve taken Phenergan for years and had no problem until 2 months ago and now it does the same thing. Anyone experience this with these drugs? For someone with chronic migraines with nausea this is a problem. So far zofran seems to be ok but this is one of the scariest feelings. You literally want to die and can’t stop moving. Be cautious if all these drugs they give you for nausea."

Was this helpful?YesNo
6 Report
  • Anonymous
  • Taken for less than 1 month
  • August 22, 2019

"I went to the ER due to having a headache and it caused my anxiety to shoot through the roof, my speech garbled and my arm feel numb. I have severe health anxiety. Got to the hospital and they decided it they were giving me a migraine cocktail. The cocktail included compazine. I have never in my life felt the way after I have since taking this drug. I wanted to run away and that was on Sunday . Its Thursday and my anxiety is still through the roof. I would have much rather dealt with the headache and all the other symptoms then to feel like I do right now. This drug should never be given to anyone ever."

1 / 10
Was this helpful?YesNo
6 Report
  • Horri...
  • Taken for less than 1 month
  • April 28, 2023

"I remember thinking I wanted my migraines back because of how this med made me feel. I still feel horrible and jittery and panicky. When they gave it to me I wanted to run and I couldn’t sit still and I was freaking out. I do not recommend this at all ever."

1 / 10
Was this helpful?YesNo
2 Report
  • Ribre
  • Taken for less than 1 month
  • April 9, 2021

"Went to the hospital after throwing up blood and was given compazine. I specifically asked for phenergan, (can’t have zofran) and this compazine was the worst drug I’ve been given. I immediately felt intense anxiety and wanted to leave. Ended up ripping out my IV myself and running out. I felt like I was going to life was over. I’m still anxious 24 hours later. I would highly recommend avoiding this med. I’m angry that anxiety is documented in my charts and they didn’t warn me of side effects. I have severe medical trauma already. I was also given the pill form for about a week before and I didn’t realize it was causing major anxiety. Absolutely horrible, I can’t believe this happens so often."

1 / 10
Was this helpful?YesNo
4 Report
  • Bee
  • Taken for less than 1 month
  • March 28, 2021

"I went to the ER for a post-lumbar puncture headache and was given a torodol, Benadryl, and COMPAZINE cocktail. As SOON as the COMPAZINE went in, I immediately started shaking and couldn’t stay still. It’s like I was fighting myself inside. I couldn’t figure out why I was so jittery. I kept making excuses to get up and move. I wanted to take my IV out and leave. I’m home after 5 hours and I still can’t rest. I’ve had both Benadryl and torodol plenty of times so I knew it wasn’t those. I just took 2 Benadryl to try and calm down enough to sleep. Man I will NEVER try that again. I had no idea it would do that! I regret every second of it! I’d rather have the headache and nausea. Bad drug!"

1 / 10
Was this helpful?YesNo
4 Report
  • Alex
  • Taken for 1 to 2 years
  • February 7, 2022

"I have been to the ER twice for severe nausea and vomiting due to anxiety and the first time they administered compazine with Ativan and it worked wonders. The second time they had just administered compazine and I noticed it really does help with nausea along with anxiety induced nausea but without the side effects of benzos. After that my I asked my PCP if I can have a prescription of the 10 mg tablets and now I take it either if I’m very nauseous and Zofran doesn’t work (I don’t want to build a tolerance to comp.) or if I’m feeling down with anxiety due to MDD because it helps lifts my mood and makes my heart feel at ease especially for the next day. I don’t recommend taking compazine if you have never took an antidepressant or if you don’t have anxiety/depression due to the nasty mental effects an antipsychotic can do."

10 / 10
Was this helpful?YesNo
3 Report
  • Anonymous
  • Taken for less than 1 month
  • December 19, 2022

"Please do not take this medication. I went to ER for a week long migraine. They gave me this along with something else. I can’t take Benadryl so I refused that. Minutes after it was put in my IV, my heart was in the 140s for hours (I already suffer from anxiety and panic attacks and was already nervous). Mind you, I’m on metoprolol as well, which lowers your heart rate, and even that didn’t bring it down. I was restless to the point of insanity, scared, anxious, and alone, and had a panic attack. I had to call the nurse who sat with me while I was having a full-blown panic attack. He was great, thankfully. After discharge, the panic, fear and restlessness lasted hours. I couldn’t be alone because I was so scared. I am also sensitive to medication and refuse a lot of stuff due to a bad prior experience with something. This is why I do not trust anything anymore. This drug was horrible and I recommend you DO NOT take this drug ever."

1 / 10
Was this helpful?YesNo
2 Report
  • User
  • Taken for less than 1 month
  • July 11, 2022

"I went to the ER Saturday night after a terrible migraine. The pain was so bad, nothing was helping. Vomiting too. They finally admitted me and gave me Toradol, Compazine both through an IV. within 10 minutes, I felt like I was panicking. I couldn't sit still. I just wanted to run out. I had to get a CT scan and I just wanted to run out! It was so scary and so weird, I thought it was just me but after reading the side effects I see how "normal" and frequent it is. Once I was on my way home, anxiety persisted. I took a quick shower and went to sleep. Thankfully I was able to fall asleep because I was so drowsy, but I basically slept the entire next day. Anxiety lasted about 24 hours. They gave me a prescription for this medication, I will NEVER take this medicine as long as I live. it was TERRIBLE!"

2 / 10
Was this helpful?YesNo
2 Report
  • Mama...
  • Taken for less than 1 month
  • June 12, 2022

"I had a severe headache from a post spinal tap. I had to go to the ER. The nurse brought me in meds through IV and said she was giving me a "headache cocktail". Next thing I knew she walked out of room and I immediately went flying over the cuckoos nest. I started hitting the call light over and over and the nurse just said it's okay it's the medicine. I ripped out my IV and started screaming for help. I thought I was going to die. She came in our back in an IV they gave me not one not two but THREE doses of Ativan. I had to call my mom to get me from there. I just wanted to go home and sleep. My mom took me to her house and made me sleep there. It took a long time for me to fall asleep. When I finally slept it was for about 14 hours. I woke up still feeling off but my headache was back and I refused to go back to take that med again. I tried to eat, bathe, everything nothing worked. It took about 24 hours to fully wear out of my system. DO NOT RECOMMEND"

1 / 10
Was this helpful?YesNo
2 Report
  • Yumi
  • Taken for less than 1 month
  • June 13, 2022

"I’m so glad I’m not alone in this. I was given this drug for a migraine also. It was my first time ever having a panic attack. Now I’m suffer from them on a regular basis and I believe it is because of this cocktail. It’s extremely hard for me to accept meds at the hospital anymore. I’m too terrified that I’ll have that reaction again."

1 / 10
Was this helpful?YesNo
2 Report
  • Kia
  • Taken for less than 1 month
  • April 13, 2022

"I went to the doctors May 23rd 2022 I was seen at the ER at the hospital I went for head pressure and I told them I haven’t been feeling like myself lately. So they took me back n gave me this and they told me they were giving me a lil Benadryl to take the pressure away out my head. But the whole time they me gave Benadryl and compazine without me knowing. So 10 mins later the meds start kicking in really fast I got real hot n start panicking ready to jump out the bed and run away. The nurse came in laughing asking me do I feel like my skin is leaving my body I told her yes and start crying. She was like your fine and put a cold napkin around my neck. I still was panicking ready to pull my hair out. Hours later when it was time for me to leave I told them I felt like I was going to open car door on the way home. So they kept me a little longer and gave me another IV to help drain the meds out of me. I still was shaky and anxious and I couldn’t stop moving. I felt like I was losing my mind"

1 / 10
Was this helpful?YesNo
2 Report
  • Jacob
  • Taken for less than 1 month
  • August 17, 2021

"DO NOT TAKE!!!! I was actually given this for chest pain. I could have clawed my own skin off and was so annoyed by everyone. Complete psychosis. It took 48 hours to wear off and about ten doses of benadryl. Absolute worst experience ever. Dr acted like it was no big deal and the nurse said most everyone has a bad reaction to it. I ask why they would anyone give this drug. Certainly didn’t help my chest pain. Dumb dumb dumb"

1 / 10
Was this helpful?YesNo
2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Anxiety

Care guides

Medicine.com guides (external)