Pazopanib for Renal Cell Carcinoma User Reviews (Page 3)

Brand names: Votrient

Pazopanib has an average rating of 8.2 out of 10 from a total of 58 reviews for the treatment of Renal Cell Carcinoma. 78% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Pazopanib

Anonymous
July 24, 2016

"My husband started 800mg Votrient 12 months ago 3 months post right renal nephrectomy with grade 4 renal cell carcinoma nodules in both lungs. CT scans 3 months later showed all nodules had shrunk, last 3 CT scans have revealed no change and he is stable BUT he is suffering from massive bouts of diarrhea as in some days / nights 10 or more times, he finds drinking the required amount of water makes him nauseous but he looks dehydrated, pale and is lethargic. Because of the urgent diarrhea he is always worried about going places unless he knows where he can rush to the toilet so he tend not to go far so this really impacts his life, he also has vomiting at times. His specialist only says to take anti diarrhea tablets and prescribed Maxalon."

5 / 10

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Kiwib...
Taken for 5 to 10 years
March 9, 2021

Votrient (pazopanib) "Using Votrient Jan 2013 until July 2020 Had right kidney removed Nov 2011 on diagnosis of my cancer. Metastasised in my submandibular and parotid glands in Sept 2012 starting Votrient Jan 2013. SE’s appear to improve over the years, main issue was blood pressure and diarrhoea. I stopped Votrient to try SRT which appears to be working."

8 / 10

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Des2e
Taken for 1 to 6 months
December 5, 2016

"Had radical nephrectomy Aug 2014 and I was clear until Jan 2016 when spots found on both lungs. Had ops to remove the cancer on lungs (big mistake). Cancer returned within 6-8 weeks. Started Pazopanib 5 mths ago. It's working!! Lung spots have shrunk. Side effects seem to come in waves for me. I'll have a few weeks of normal bowel then I'll have a week or so when it's bad. Hair has turned white (I'm 47). Bad taste in mouth, I've lost weight (10lbs), appetite comes and goes but it's mainly not there. Ulcers in mouth have gone but can't get rid of the ones in my throat. Blood pressure is normal. I feel tired at the end of the day (earlier than usual) but no real fatigue. Overall I'm feeling good and still working. Keep fighting all, God Bless"

10 / 10

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Frequently asked questions

Anonymous
December 27, 2021

Votrient (pazopanib) "My husband had a nephrectomy of his left kidney, it had spread to his left testicle and had the testicle removed as well. Before the operation, the surgeon said that the mass had been slow growing for roughly ten years. He is 67, and in mostly good health outside of the cancer. It has been a year and a half on Votrient. The first dosage was too high and caused him a few hospital visits to stabilise his liver function. Now he is on half that dose, the only prominent side effect is the occasional nausea, fatigue and vomiting/fainting spells. Of course his hair has also gone completely white. He is very thin and struggles to put on weight but has a healthy appetite. It seems that this dosage is working, his cancer cells have shrunk. He goes for a PET scan twice a year and has been clear so far. In 4 months will be 2 years since diagnosis. So far the medication is working. The diet seems to be the trickiest part and I would recommend that you see an expert dietician. A specific diet is NB."

8 / 10

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Sally
Taken for 1 to 2 years
December 23, 2016

"My husband was diagnosed RCC stage 2 in Oct. Last year.He had 1 kidney removed and was on pazopanib 800 mg.But this has been reduced to 400mg due to severe side effects. Now he takes the 400mg for 10 days and discontinues For 3 days every time.His oncologist is happy with the tests results for now ,at least for around 9-10 days per month, he can eat a little more."

8 / 10

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Are you taking this medicine?

For...
Taken for 1 to 6 months
November 24, 2021

Votrient (pazopanib) "Daddy has Clear cell renal cell carcinoma. He was first put on Opdivo and Yervoy--an immunotherapy. This worked great! It was shrinking my dad's tumors that he had in his stomach, liver, lungs, and right atrium (heart). It even got rid of all the cancer in his stomach. The cancer spread to his brain and he had to be put on chemotherapy. Votrient had a lot of side effects. Nausea, super high blood pressure, major fatigue, and chemo brain fog. He lost 80 pounds on votrient from not eating. Became frail and fragile and we were afraid he would die from malnutrition. We begged the doctor to take him off it because she even said he wouldn't live much longer on it, but the issue was the votrient was SHRINKING the tumors in his liver. This was a sign it was working. His doctor put him on dexamethasone 2mg which helped his energy levels and his appetite tremendously. He gained 40 pounds! He was on votrient 6mos but BP and brain fog got worse though so she then put him on Avastin."

5 / 10

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Bink
Taken for 2 to 5 years
November 30, 2016

"I have stage 4 RCC. the drug work for 4 years, the docs were surprised that it worked so long, I had most of the Side effects diarrhea, hair turning white, stomach cramps but better than the pain. The tumors ate thru a rib, 2 neck vertebrae and my kidney and some small ones in my lungs. The kidney and verabras were removed. The tumors double in size I am now on Afinitor. "

10 / 10

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Bobcoos
Taken for 5 to 10 years
July 2, 2024

"I was diagnosed Christmas Eve 2007 with a stage 4 tumor on the right kidney. Had nephrectomy of the R kidney, adrenal gland, and a portion of the renal vein in Jan 08. A few months later had a tumor on the L adrenal gland removed. In 2014 RCC met on the left shoulder blade; had 1/3rd of the blade removed. In 2015 a scan showed 7 lesions of various sizes on the liver. Started on 800 mg daily of Votrient in March 2015. Overnight my hair went from dark brown to grey. This is the only side effect I have experienced. The tumors on the liver have gone from 7 to 2 in about 9 years. I do have fatigue, but it is due to a lack of adrenal glands and no hormones. I take synthetic meds for fatigue and replace some hormones. After 5 years, I started having severe diarrhea, so I take a combo of Imodium AD and a probiotic. It helps control it. I feel great as of today, but early on with RCC, had problems walking but could still function. Daily exercise is a must even when one does not feel up to it."

10 / 10

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Sourav...
Taken for 1 to 6 months
January 26, 2022

"My father in law (age 76) suffered from Renal Cell Carcinoma. After nephrectomy of the affected kidney, he was fine with single kidney for more than 1 year. His creat was around 1.1 to 1.2 (with single kidney). He did not have any high BP or Diabetes. However, after routine CT few questionable nodules were detected in lungs. Without cross verification (like repeat scan / biopsy / PET scan etc.) his oncologist prescribed him: Pazopanib 800 mg per day. Soon after starting the medicine, his BP became extremely high (200/100) and creatinine started jumping from 1.1, 1.8, 2.2, 2.8, 3.2 and 3.5, in 3 months. His Platelet dropped from 1 65000 to below 50 000 with lot of side effects (vomiting, diarrhea etc.). We repeatedly informed the oncologist, but he was in denial mode. When we consulted nephrologist, he stopped the medicine. The deteriorating renal function stopped at creat 3.5. But, unfortunately his Platelet did not recovered from below 50000 mark and he died due to a celebral hemorrhage."

1 / 10

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Breed...
December 21, 2010

Votrient (pazopanib) "This is my husband's second month on Votrient. He had a CT today, and it shows significant shrinkage in the tumors in his lungs. The only side effect he is experiencing is high blood pressure."

8 / 10

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Anonymous
May 8, 2011

Votrient (pazopanib) "Taking 600 mg of Votrient. Taken at night seems to reduce the side effects significantly."

5 / 10

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117 Report

MrsCN
Taken for 1 to 2 years
January 12, 2016

Votrient (pazopanib) "My husband has been on Votrient for a year...some gastric issues,foot pain....but overall his tumors are shrinking"

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66 Report

rcbri...
January 30, 2011

Votrient (pazopanib) "Very effective. Have lost a lot of weight, but side effects not as extreme as Sutent for me. Started taking 9/20/10 still on it 2/11."

10 / 10

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80 Report

Shotsy
Taken for 1 to 2 years
August 6, 2018

Votrient (pazopanib) "I've had a very good experience with this drug and have been on it since Nov 2016. Diarrhea has been a side effect, but a small price to pay to feel overall very good!"

10 / 10

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22 Report

llllll
Taken for 1 to 6 months
May 21, 2018

Votrient (pazopanib) "With Votrient I had no major side effects only loss of appetite and weight loss so far. Slowed progression of cancer down significantly"

10 / 10

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21 Report

Sume
Taken for 1 to 6 months
November 3, 2016

Votrient (pazopanib) "My father had passed away of taking pazopanib just for 3 months due to tumour rupture because of this tablet...please do not consume it.."

1 / 10

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manns...
Taken for less than 1 month
August 7, 2017

Votrient (pazopanib) "Started treatment 7 days ago no real side effects only lethargic all the time."

6 / 10

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8 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.