Skip to main content

Xtampza ER User Reviews & Ratings (Page 2)

Xtampza ER has an average rating of 3.7 out of 10 from a total of 167 reviews on Drugs.com. 24% of reviewers reported a positive experience, while 63% reported a negative experience.

Reviews for Xtampza ER

  • Sparky
  • May 8, 2019

For Chronic Pain "Until last weekend, I had three nights of good sleep. It takes 4 hours (zombie time) to come on. It then helps with pain for 5.5 hours. It is formulated using fatty acids from wax. It does not mix with water; you must eat some fat for it to work, which sucks at bedtime. If I take it just before falling asleep, I wake up to pee and then I lay awake for 3-4 hours. If I take it 4 hours before bedtime, then I have 4 hours to go to sleep. I have found a way to take it and get a good night's sleep! I get up at 5:00 AM, eat a Siggi's Triple Cream yogurt and a few tablespoons of heavy cream in a glass, take the dose, then back to sleep. I wake up at 8:30-9:00, and it's working. Second dose between 2:00-3:00 PM. FWIW (for what it's worth), coconut oil has 14g of fat per tablespoon. I talked to my pharmacist, and they take the coupon for generic OxyContin, and 60 will cost me about $110 a month."

8 / 10
Was this helpful?YesNo
77 Report
  • TKano
  • Taken for 2 to 5 years
  • April 6, 2019

For Pain "After nearly a year of using 18mg Xtampza (started at 9mg and worked up to 18mg), I’ve found waking an hour early and taking it with high-fat yogurt and sleeping another hour leaves me feeling refreshed and on my way. It only seems to work for 6-8 hours so I use 20mg baclofen and 10mg oxy for breakthrough between doses. It also helps to use Tylenol in addition as it synergizes both forms. Also, if you can get your BP up for at least 20 minutes by taking a fast-paced walk it also helps get the meds into your system much quicker. It’s not always easy but exercise helps in every way if you’re able. It’s not the perfect medicine but without it I would be miserable and likely unable to work and tolerate the cancers and radiation proctitis nearly as well as I am."

Was this helpful?YesNo
77 Report
  • Nytowl
  • Taken for 1 to 6 months
  • July 4, 2019

For Chronic Pain "This drug made my nightmare even worse. In the 5 months I was on it, it caused me to gain nearly 60 pounds! Over 10 pounds a month! I had to literally buy bigger clothes every 2 weeks. Thank goodness for thrift stores! As for the pain relief, it didn't do as well as the Opana that I was on prior to the Xtampza. Then Opana was pulled from the market suddenly, though, supposedly in the reaction to the 'opioid crisis,' so I needed something to replace it, and the doctors gave me Xtampza that fall. I suffered with worse pain relief and rapid weight gain for 5 months, until they finally switched me to something else! I would not suggest this medicine to my worse enemy! You may not suffer from the extreme weight gain like I did. You may get better pain relief than I did. But beware, because some of us have *awful* side effects from this stuff!"

1 / 10
Was this helpful?YesNo
74 Report

Frequently asked questions

  • Sleep...
  • Taken for 1 to 6 months
  • February 7, 2019

For Chronic Pain "In a word...awful. I've been on 2x18mg Xtampza ER for over a month now, after my sadistic insurance co refused to cover OxyContin, which I've been taking 2x20mg since 07 for severe pelvic floor pain. While Xtampza is designed to avert abuse, it most definitely is not designed for any credible chronic pain relief. First and foremost, it's doing very little for my pain. It takes FOREVER, like 2+ hours(!), to work, and lasts 3-4 hours, at best. I'm being generous saying it 'works', since it barely takes the edge off my pain. I still have to take breakthrough meds, even while this junk is supposed to be in full effect. I regularly experience strong side effects described by other reviews, including headaches, nausea, sleeplessness, and high anxiety. It's amusing to hear the claims of this med being 'exactly the same' as OxyContin - the one thing that actually worked."

1 / 10
Was this helpful?YesNo
74 Report
  • Anonymous
  • February 7, 2020

For Chronic Pain "I was forced off Oxycontin by my insurance plan and placed on Xtampza and it definitely does not work for my pain as well as oxycontin. I was told they are supposed to be the same medication except for one is tablet and one is capsule, but they are not as far as I (my body) is concerned. Also because this drug is so expensive the pharmacy does not even carry it, I am supposed to call a week or so in advance to make sure they can try to get it shipped in so now I'm facing possible issues of not being able to get my meds when they are due to be filled. This is causing all types of issues and hoops for me to jump through just to get my prescriptions."

3 / 10
Was this helpful?YesNo
63 Report

Are you taking this medicine?

  • Blondie
  • Taken for 1 to 2 years
  • April 12, 2020

For Chronic Pain "I’ve been on Xtampza since January 2019. I have post laminectomy syndrome, spinal stenosis, Levoscoliosis, rheumatoid arthritis, facet joint arthrosis, DDD, and a few herniated discs in my C-spine and L-spine and I’m only 35. As with all medications, everyone’s body works different in regards to medicine. For me, Xtampza works great and I find that it covers my pain most of the time for a full 24 hours. Granted my pain does change with the weather. However, I have found that Xtampza works better than OxyContin for me."

10 / 10
Was this helpful?YesNo
60 Report
  • Relen...
  • Taken for 6 months to 1 year
  • August 29, 2018

For Pain "Xtampza gave me my dignity back. I was bedridden for over four years straight and after literally trying every pain medication in existence (including Fentanyl, spinal nerve stimulator, and pain pump,) I am now able to function at a much higher level. This medication is ideal for those who metabolize meds rapidly, which can be discovered by taking a P-450 blood test. Because of the abuse deterrent capsule, the beads of medication break down slowly. In my experience, this keeps side effects like nausea down. It lasts longer than any ER med I have tried and is more stable in its release. I am losing weight gained previously. The capsule can be sprinkled on apple sauce, but needs to have a fat source to break down properly. A cracker or cookie easily solves this, which is a good practice to have in place with any med to protect stomach lining. I am prescribed a breakthrough med besides Xtampza. I am thankful beyond words that this has worked for me."

10 / 10
Was this helpful?YesNo
76 Report

More FAQ

  • Pete
  • Taken for 1 to 6 months
  • April 2, 2018

For Chronic Pain "Dangerous erratic medication. Package says to take with the same amount and same type of food every dose. How can you do that? I can tell you this for sure. Sometimes it works, sometimes you OD, sometimes it does nothing for the pain. You never know what you will get. This medication is going to OVERDOSE PEOPLE! You can tell the good reviews on here were written by the drug maker. The only truthful ones sound like this."

1 / 10
Was this helpful?YesNo
78 Report
  • Rocky
  • Taken for 6 months to 1 year
  • June 21, 2020

For Chronic Pain "I was started on Xstamza ER in Jan 2020. CMS removed Oxycontin ER from the formulary in 2020 and switchwd to Xstamza ER mfg by Collegium. My pain group started me on 18 mg Xstamza vs the 20 mg Oxycontin ER. After three months told PM it was not working. She upped it to 27 mg Xstamza. I hit the coverage gap in May. I refuse to pay over $100+ for a drug that does very little so when I had my tele-healrh appt on Friday told hsr it really was doing little to help me and I refused to have it filled. Its just shy of being a worthless pain medication. Have heard from several the same thing."

Was this helpful?YesNo
51 Report
  • Cher
  • September 13, 2019

For Chronic Pain "I too was forced to use something other than MS Contin. Xtampza was chosen and I suffered through it for 3 weeks before calling my physician in tears to let him know that I had no relief whatsoever from the pain and as well I was experiencing headaches diarrhea and deeper depression. I was then given a prescription for Belbuca film. Would have liked to try it but insurance doesn't cover it and it costs $475 a month! What are we to do???"

1 / 10
Was this helpful?YesNo
58 Report
  • Seaho...
  • Taken for less than 1 month
  • September 4, 2019

For Chronic Pain "At my request, due to daily soaking sweats I went from 8 years of methadone for chronic spinal pain (add severe psoriatic AR + RA) to Xtampza 13.5 twice per day. The pharmaceutical company has played a joke on us with this one. They need to just trash the Xtampza & start all over. I never knew just how well the methadone was working (despite sweats) to lessen my pain until I switched to this garbage."

Was this helpful?YesNo
58 Report
  • Most...
  • Taken for less than 1 month
  • February 8, 2020

For Chronic Pain "So, my doctor thinks Xtampza ER is the safest choice? Even though plasma levels are hugely dependent on high fat food. I think this drug is dangerous. Give me plan old, cheap, generic, oxycodone any day. Every day since being switched to Xtampza has been agonizing."

1 / 10
Was this helpful?YesNo
52 Report
  • Brian
  • Taken for less than 1 month
  • July 18, 2018

For Chronic Pain "Just took capsule 13.5 mg and sprinkled on yogurt, it hit me in 10 minutes extremely loopy but yes it really works, those people out there saying that it doesn’t work probably may have become tolerant of everything. Take your meds as prescribed people, do not overtake, this stuff works great, I feel 0% pain right now for the first time in 20 years"

10 / 10
Was this helpful?YesNo
64 Report
  • Skidbo
  • July 13, 2018

For Chronic Pain "I have taken all the usual prescription opiates over the past 14 years almost daily. Xtampza is very inconsistent and dangerous and therefore ineffective. My experience is that it is not time released. The withdrawal is the worst yet I paid a lot of money for this fancy capsules which is just a marketing scheme. I would not recommend this so called pain med to anyone. Big pharma guinea pig!!"

1 / 10
Was this helpful?YesNo
64 Report
  • Painm...
  • Taken for less than 1 month
  • March 14, 2019

For Chronic Pain "I have 4 herniated disc in my neck, two failed right shoulder rotator cuff surgeries, back surgery on L5 and esophageal cancer that has not spread (thank God). I'm starting on Xtampza ER in a few days for this chronic pain and was very nervous however, it's time. I was taking four 15mg oxy IR. Down to four 10/325 Percocet and will now be trying two x 18 Xtampza plus one break through. After reading some of the real comments from people switching to Xtampza, that the drug actually works I feel more confident. I will report back once I'm taking to give full and honest report. I will give honest report back as I'm not looking to get high - I just want to manage the pain so I can live a sub par but somewhat normal life, what I have left. Good luck to all of you with your pain management issues"

Was this helpful?YesNo
58 Report
  • DerekFL
  • Taken for 1 to 6 months
  • January 2, 2020

For Chronic Pain "I was on Fentanyl 50mcg/per hr changing the patch every 48hrs before asking to be switched to MS Contin 60mgs/TID and that stopped working after over 3 years of being on the same dosage, finally my doctor suggested I switch to Xtampza ER 36mg/BID. Once I switched to Xtampza ER my pain not only increased but my breakthrough medications had to be increased to Roxicodone 30mg every 4-6hrsPRN. Finally after 3 months on Xtampza my doctor put me back on Exalgo 16mg/24hr and left me on the Roxicodone 30mg every 4-6hrsPRN but I hardly have to use more than 3 of those per day and am no longer suffering any pain."

1 / 10
Was this helpful?YesNo
50 Report
  • SoB
  • Taken for 6 months to 1 year
  • June 12, 2023

For Chronic Pain "I’ve been on high level opioids for 23 years due to a debilitating and disabling accident. For 18 years: six 80mg OC with six 30mg Roxycodone for breakthrough pain. Then, it was six 60mg MS Contin ( morphine ) with the six 30s. Then, the opioid crisis. From 540mg daily down to 90 in a year!!! The docs and insurance companies are the criminals here. If 90mg is “appropriate” then why was I on 540mg/day? And 660mg of OxyContin and oxycodone before that?? So, now we have Extempa. Completely worthless. That’s all I can say. It does nothing for pain. All of the poor souls like myself who have always followed the rules with narcotics contracts and pee tests are the ones who got completely screwed! Now, try getting a pain doctor to titrate! I’ve been on the same dose for 3 years; completely tolerant to it. God bless you all whom continue to suffer."

2 / 10
Was this helpful?YesNo
17 Report
  • Sparky
  • Taken for less than 1 month
  • February 13, 2019

For Chronic Pain "I was just switched to Xtampza ER, took my first dose this morning. My doctor did not mention food at all but I always read about the meds I take. In BOLD they say to take this Med with food. If you take it in the morning before eating you will get maybe half the dose. The oral bioavailability goes up by as much as 150% with a high fat/high calorie meal. I called the manufacturer but they were unable to tell me exactly what is a “high fat/high calorie meal”. I ate some walnuts, two slices of Ezekiel bread toasted with butter and about a cup of Promised Land chocolate milk. They also say that you should eat the same amount of food with each dose to maintain even blood serum levels. My guess is it is this lack of knowledge that is causing some patients to find this drug ineffective of erratic. I’ll probably settle on 1/4 cup walnuts, couple of eggs (boiled) and maybe a Boost Plus (or chocolate milk). In any case it seems to be working."

8 / 10
Was this helpful?YesNo
54 Report
  • Miami
  • Taken for less than 1 month
  • September 8, 2018

For Chronic Pain "I was put on this medication for chronic back pain and primary progressive MS. I had been on OxyContin and oxycodone. The medication simply doesn’t work for me. My insurance company finally approved my old medications for me. I understand the abuse that goes along with the opiate medications. However I don’t abuse it. I never will either. I hate taking pain medications but I have no choice. Good luck with the pain for all of you."

2 / 10
Was this helpful?YesNo
57 Report
  • Retired...
  • Taken for less than 1 month
  • February 8, 2020

For Chronic Pain "Started this medicine three weeks ago and it doesn’t help much at all for pain. Don’t do well with capsules so open it up and put contents on yogurt to consume. For breakthrough pain, dropped from 30mg oxycodone to smaller quantity of 15mg and that hasn’t worked either. Now, constant pain level worse than ever. Worse, three of the capsules were empty."

2 / 10
Was this helpful?YesNo
46 Report
  • TCald
  • Taken for 6 months to 1 year
  • August 14, 2023

For Pain "I took Xtampza ER for almost a year. It provided reasonable pain control for about 6-8 hours when taken with a high-fat meal or snack. The fat is needed to break down the abuse deterrent coating. Sadly, most pharmacists fail to tell patients that. I put on weight due to the extra fat requirement. I ended up changing meds due to the cost and weight gain. Xtampza is okay, but I think there are easier/more effective meds out there."

7 / 10
Was this helpful?YesNo
14 Report
  • Living...
  • Taken for 6 months to 1 year
  • May 3, 2018

For Chronic Pain "I have had a neck fusion and I am herniated from L2-S1, stenosis, 3 bone spurs , bursitis in my hips and arthritis. I live with chronic pain every second of everyday! My pain management dr had me on 30mg Oxycodone 6x a day ,and soma. He started me on extampza ER 18mg. It took a few days before I noticed I wasn’t taking as many Oxycodone because the extampza was helping me. I’m now on 15mg Oxycodone 4x a day and twice a day extampza and I feel great! I don’t want to look and feel high, I’m just looking for less pain. While taking extampza I’ll get a burst of the med which I like Extampza gives me exactly what I need! It’s my “got my life back med” there are some days I’ll only need 1 oxycodone! I don’t like taking meds all day every 4-6 hours this is just 2 a day! I’m feeling great!"

10 / 10
Was this helpful?YesNo
57 Report
  • Zykull
  • Taken for 6 months to 1 year
  • January 10, 2019

For Chronic Pain "I have been on Xtampza ER 18mg 2x a day, also on oxycodone 10/325 3x daily. This morning I thought I would try something different. Acetaminophen boosts oxycodone, so I said to myself that tylenol probably would boost an extended release for of oxycodone and guess what, 0% Pain. I take 1.5 oxycodone and 1 xtampaza ER and another tylenol capsule, extremely loopy but wow does it help. I take for Broken disc, herniated disc, torn ACL, torn Rotator Cuff and Vascular problems as well. Just take 1 or 1.5 Oxycodone and one 500mg tylenol with the xtampza."

9 / 10
Was this helpful?YesNo
52 Report
  • GemTex
  • Taken for less than 1 month
  • April 19, 2020

For Chronic Pain "Had spinal fusion surgery that left me with more pain than I had presurgery. I was burning through 10/325 Percocet so my pain management switched me to Xtampza 18mg. 1st night had such a bad nightmare I refused to go back to sleep.This med caused insomnia on some days or sleep with horrific dreams. As for pain it did manage my pain but I hope I am not required to be on it for a long amount of time. I mixed it with 1 tablespoon of peanut butter and it seems to work well that way. It is also on the pricey side even with insurance."

8 / 10
Was this helpful?YesNo
42 Report
  • Feel...
  • April 25, 2019

For Chronic Pain "Since I was just switched to Xtampza ER on 4-19-19 and have been taking 9mg twice daily for a week. So I really can't say too much other than I have had a headaches daily starting one day after starting the medication & has not let up yet. I was told that this drug would last longer than my current medication which was OxyContin 10 mg twice daily. So far neither have lasted the 12 hours as it claims. I am lucky to get 5 to 6 hours of relief per dose. Neither gave me complete pain relief but some was better than none. My pharmacy said they have never had anyone prescribed this medication before me. I was lucky enough to get my script at my monthly doctor visit. Pharmacy had to special order medication but could not order it until they got a prior authorization from the doctor or my insurance would not process. At this point I do not feel that I am getting the relief I was getting previously as far as the length of time. I was down for 2 days with a bad headache out of the 7 days on this medication."

2 / 10
Was this helpful?YesNo
49 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.