Skip to main content

Xtampza ER for Chronic Pain User Reviews (Page 4)

Xtampza ER has an average rating of 3.8 out of 10 from a total of 134 reviews for the treatment of Chronic Pain. 25% of reviewers reported a positive experience, while 62% reported a negative experience.

Reviews for Xtampza ER

  • Longh...
  • July 10, 2017

"Have had chronic lower back pain for over a decade. Insurance co made me switch to Xtampza from OC. First few weeks were a bit of a challenge because we had to find what dosage strength and dosing frequency was best for me. But once we got through this, I find the drug works well when I use as directed particularly as it relates to diet. Also have my backup of fast acting pills when I have breakthrough pain. I think people that say this drug doesn't work aren't being dosed appropriately or they have just been on high doses of OC alongside short-acting narcotics for so long that they are just too far along to be helped by anything new because your bodies have just gotten so used to your incredible high dose OC regimen. Sorry but push through"

8 / 10
Was this helpful?YesNo
37 Report
  • RoyT
  • February 19, 2017

"I have stenosis with degenerative disk disease. On low dose and have not had surgery. xtampza is better than not having any pain relief but not by much. Very slow onset, lasts perhaps 8 hours (same as oxycontin) and unpredictible relief depending on diet."

3 / 10
Was this helpful?YesNo
38 Report
  • Mac
  • October 5, 2020

"I have been suffering for many years with chronic back pain. I have DDD, DJD, Stenosis, arthritis , bulging disks, herniated disks and the list goes on... I was switched to this from oxycodone short acting in order to limit the amount of pills I was having to take daily which I was all for. I made it 3 days and couldn't take it anymore & since I still work and need to work to get paid, I called my doctor and she switched me back to the quick release. This stuff doesn't work and I can't understand why. If its the same as oxycodone then it should work but it absolutely doesn't. I am now scared to try any extended release because I don't want to go through suffering for 3 days again. Maybe this stuff works but from the reviews I have read after my experience I'd have to say it may help 1 out of 25 people which is a very poor statistic."

1 / 10
Was this helpful?YesNo
23 Report

Frequently asked questions

  • Hurting...
  • January 31, 2018

"Medication takes 3-4 hours to work no matter what you eat while taking it. When and if it starts to help with the pain, it stops in 3 or 4 hours. Sometimes it comes on so strong that I have a panic attack. I figured I would adjust to it, but after a month I have not."

2 / 10
Was this helpful?YesNo
34 Report
  • Pearl...
  • Taken for 1 to 6 months
  • September 9, 2018

"Works great but causing severe sore throat. Taken steroids and antibiotics with no relief. Everyone including pharmacist says it would not cause sore throat but ever since I started these have had a severe chronic sore throat. If it wasn't for sore throat would love it it. It helps with back pain much more than MS-contin. "

7 / 10
Was this helpful?YesNo
31 Report

Are you taking this medicine?

  • Jim
  • Taken for 6 months to 1 year
  • August 30, 2018

"I was taking 30 MG of oxycontin per day when Cigna suddenly stopped covering it. The Doctor switch me to Xtampza ER 13.5 MG twice a day and I was quite apprehensive after being on Oxycontin for the past few years for an in-operable chronic back condition. I have been very happy with the new medication. It works as well as what I had been taking and it seems to last longer. With Oxycontin I knew when the time was up with this medication I can go two to three hours over the time for the next dose and not have a problem. I also have the feeling that getting off this medication will be easier than getting off the Oxycontin. I know it's basically the same medication but it just seems to work differently."

8 / 10
Was this helpful?YesNo
31 Report
  • Kat
  • Taken for less than 1 month
  • January 20, 2022

"I've been a pain patient for nearly 20 years due to Ehlers-Danlos syndrome. Switched from generic MS Contin 15mg twice a day to Xtampza 13.5mg twice a day. One word: torture. Constant GI upset with diarrhea and feeling like my insides are writhing with worms. A complete lack of dreaming (no darkness, just like being turned off and on again) with horrifying intrusive thoughts and mood swings. Pain in parts of my body where I didn't have pain before, or where pain was previously well-controlled. Feeling dangerously high and then going into total withdrawal (I kept the Narcan on my bedside table and told my family to check on me). I took it with a fatty meal, the same meal every time, and had a different experience every 12 hours. At no time did I feel safe taking this medication. This has left me feeling terrified to try anything else and suspicious of my doctor's reasons for switching me. I firmly believe this medication was manufactured to scare people away from opioids."

1 / 10
Was this helpful?YesNo
16 Report

More FAQ

  • Fred
  • Taken for less than 1 month
  • October 27, 2022

"A BIG CAUTION - This drug requires you to have a gallbladder and a fully functioning Bile System or your body will not absorb it. If you are being taken off another Opiate you will suffer major withdrawal symptoms as the Xtampza won't be absorbed and you will have stopped your original Opiate. Can you spell Cold Turkey? It happened to me and it SUCKED!"

1 / 10
Was this helpful?YesNo
12 Report
  • sunsh...
  • Taken for less than 1 month
  • April 28, 2021

"Paid 200 dollars for 28 capsules of Xtampza ER. So far it has been worthless and very disappointed with this product and had to pay my insurance a $190 copay. Wow what a bad decision . Wasted money that I don't have to waste on some designer drug. Definitely will not refill. I'm afraid to take it again, I feel like they are forcing us take a product that does not work . Due to 8 surgeries and Fibromyalgia my life is tough getting through each day and night. Absolutely no help for sleep . It actually has me waking up ever to hours. Just like before I gave them $200 . I think we all deserve a refund for a drug with a lot of hype but read the reviews. Happy Trails"

1 / 10
Was this helpful?YesNo
19 Report
  • BBQGOD
  • Taken for 2 to 5 years
  • January 12, 2021

"Was on Oxycontin 20mg twice a day. Percocet twice a day as needed, 5/325mg. Never had to increase. Was switched to Xtampza a few years ago, started on 18mg twice a day, took time as no conversion chart between both meds, so ended taking 27mg twice a day, with food, worked but very strong, couldn't function so just decreased to 18mg twice a day, clear mind, pain free and taking fatty food with it as that's how it works. Switching between meds takes time, but will work, take it with food to help plasma levels, it's strong so be careful."

10 / 10
Was this helpful?YesNo
20 Report
  • Bad...
  • Taken for 1 to 6 months
  • April 26, 2018

"Xtampza works very well for being extended release. I have half the breakthrough pain and flair up's taking this med. Take it around the clock on time. Be patient with this med and find out what dose works best. It changed my life drastically for the better."

8 / 10
Was this helpful?YesNo
31 Report
  • Sammy
  • May 12, 2021

"Was forced to Xtrampza from former med , this medicine was I believe to make you ill , sick , so you don’'t want to take it . That designer drug works to make you sick . But doesn’t work to well on pain and takes hours and hours to get any pain relieving effect at all . It is also inaccurate on how they are made , there must be no controls on the manufacturer process . The 4 score is accurate, many are being forced to this medication even though it’s not effective and takes way too long to work if at all and it’s just as expensive as Perdue . I would not recommend this med unless you have no other choice and you’ll just have to force it down and be sick to try to get any pain relief at all . Take it with a NSAIDs or Tylenol if your doctor allows it . But just remember how dangerous NSAIDs and Tylenol are . Don’t take that like it’s nothing . Good luck on this one. I only wish the designers and doctors had to take it ."

3 / 10
Was this helpful?YesNo
18 Report
  • Chronic...
  • Taken for less than 1 month
  • June 15, 2018

"Have just started, seems to be working as advertised. I have had Chronic Pancreatitis for 12 years, and have struggled for years to get pain under control. Like I said before just started taking. It has been a week, I don’t have to take as much break through medicine. I can finally sleep more than 4 hours, yeah!!!"

7 / 10
Was this helpful?YesNo
29 Report
  • Sher_...
  • February 16, 2018

"Not only is this a very expensive medication even with insurance, the 18mg capsule twice a day does not help my pain one bit. What is does help me to have are abnormal, very real, and terrifying nightmares that leave me howling for help in the middle of the night, or yelling myself awake if I lie down for a nap. As someone else mentioned, these dreams are hard to wake up from on your own. Nightmares like half man, half beasts after me, a boat ride spinning out of control down an abyss, inanimate bizarre objects coming to life and after me, odd places I've visited before but haven't. I cannot deal with this, not at all, and I will not take anymore of these. At this point I would rather deal with chronic pain, than chronic nightmares and losing sleep. Acupuncture may be my next step since positively nothing medical has helped one iota. More meds have worse side effects, and cheap generics do nothing. So now what. I give up."

1 / 10
Was this helpful?YesNo
30 Report
  • Nick...
  • Taken for 1 to 6 months
  • January 3, 2017

"I have had chronic back pain for 35 years, Consisting of 7 lumbar surgeries, fusion with steel and titanium rods and screws. I have had numerous pain Doctors prescribing numerous pain meds. I considered the meds to be successful if they stopped 1/2 the pain."

Was this helpful?YesNo
33 Report
  • Shines
  • Taken for less than 1 month
  • July 24, 2022

"Was taking Percocet 10/325 for a very long while, it helped but only for 4 hrs so I had bad ups and downs. So Dr put me on this rubbish. I've been taking for a week now. This week has been hell. No relief at all. It's like taking nothing except side effects. God awful nausea. Worse back pain. I just want my percs back. This med is worthless."

1 / 10
Was this helpful?YesNo
12 Report
  • Rogue...
  • September 15, 2017

"Dose is two 36mg every 12 hours. Plus breakthrough meds. The xtampza doesn't last the full time so I've found that switching to 1 pill every 6 hours DOES WORK because there is a steady stream of meds plus the breakthrough as needed. Hope this will help."

8 / 10
Was this helpful?YesNo
30 Report
  • I...
  • Taken for less than 1 month
  • October 24, 2017

"I am on my the end of my 1st week into my second week day two. Like most of you I cried in the doctors office for fear of the level of pain I’d have to endure daily. My pain was as bad as all of yours. My first 4 days were awful then each day a bit better. I finally began taking 1/ 39 mg capsule every 3/ 0.5 hours through 6 capsules day + 4 /10 mg breakthrough pain tablets. As the days past I found I needed less break through daily and my daily pain was controlled like never before. Don’t get me wrong I endure pain and not everyday is perfect. But yes I am very pleased and wish I tried them sooner. when my OxyContin began to die down within 5/6 hours. The break through were more of a joke. Xtampza gave me my life back"

Was this helpful?YesNo
28 Report
  • Diano
  • April 21, 2018

"I have constant, chronic severe facial pain from a head & neck injury that was recently helped in a major way with stimulator implant surgery in Denver. Still need pain meds but much lower dose. Forced to use this drug thru the insurance company's refusal to continue providing Oxy ER. Was put on Xtampza for about 2.5 months, gained 25 pounds FAST without changing diet, extreme headaches with pressure like never before, every joint hurt. Dr said to maintain 18 mg/2x day dose anyway. Took one more week, gained 5 pounds more, and said enough. Got off it using leftover fast acting, now down to just occasional doses for severe breakthrough pain. Found out all my allergies and general body aches the past 13 years have been due to pain meds and my body's reaction to them so once I'm off, symptoms disappear. Wouldn't have known that without Xtampza, BUT my headaches aren't easing after being off it for a month, plus going off Topiramate. Will these headaches ever get better or is this my new normal?"

1 / 10
Was this helpful?YesNo
25 Report
  • Terri...
  • Taken for 6 months to 1 year
  • March 7, 2023

"Xtampza does not work for me in fact I believe it gives me more pain. As I get hot flashes and neuropathy now on top of my other problems. This medicine absolutely does not help me yet I’m forced to take this garbage. My insurance company pays over a thousand dollars for what is essentially garbage. My former medication worked well but they don’t want to prescribe it anymore. All this medication does is torture me. I can’t stand this. We need medication that works!"

1 / 10
Was this helpful?YesNo
8 Report
  • Nopain
  • November 17, 2017

"Actually this is the most breakthrough med in this space that has been in a long time. There are a few post on here stating that there is a “euphoric blocker”, when in fact that is completely false. It is the exact same molecule as Oxy people...just it has the best abuse deterrent on the market. And for it or lasting for you 12 hours can be a variety of things. Your metabolism, body weight, etc. Everyone body processes meds differently. “No long term effects” have not been studied because it’s only been on the market for less than 2 years...not a strong argument. Look at the long term effects that on the oxy I’m assuming you want to be switched back too. Again SAME MOLECULE!"

10 / 10
Was this helpful?YesNo
25 Report
  • anony...
  • November 28, 2020

"I have been on oxycontin for many years for chronic pain. Insurance forced me off the brand name to a still decent oxycodone ER which worked well. Now the distributor ran out, not sure if it will ever be restocked....(has been on back order forever now) my only option left was xtampza ER, which, I agree with everybody else, does not work the same as oxycontin. I had to switch to xtampza fairly quickly and now experiencing rapid heartbeat, sleeplessness, and it only seems to work from the neck up for pain effectiveness......awful stuff! I'm almost ready to pay out of pocket for the better medication."

3 / 10
Was this helpful?YesNo
16 Report
  • ttluhr
  • Taken for 1 to 6 months
  • August 23, 2017

"Works well for me now after a pretty painful period of switching/washing me out of the oxycontin regimen I was on prior. give it time to get used to and should get similar results. After all, its the same drug just packaged differently."

8 / 10
Was this helpful?YesNo
26 Report
  • Nickn...
  • October 12, 2017

"My advice would be to work with your doctor to find the appropriate dosage strength for your needs and also experiment with how often you take it (ie once in the morning for all day relief, or one cap in the morning and then another at midday). I also recommend to each this with high fat food. I've been told cottage cheese or yogurt helps. I think once you figured out the best way to take this drug, it works -- it certainly did for me. Be patient."

9 / 10
Was this helpful?YesNo
25 Report
  • nana
  • Taken for less than 1 month
  • March 26, 2021

"Have been taking this type of pain med for 1 week. Switched off Percocet. I have chronic neck, spine, and leg pain in addition a brain injury. This medication is not only expensive. I am back to pain that I had previously . Movement hurts lifting, spine, right leg and brain is like I felt after surgery. This is a shame and expensive."

1 / 10
Was this helpful?YesNo
14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.