Olanzapine for Obsessive Compulsive Disorder User Reviews

• Mom...
• Taken for 1 to 6 months
• May 20, 2017

"This medication saved my life, after years of closet OCD and anxiety, I was suicidal and couldn't take one more day. They started me at 5 mg and it's never been upped. My OCD is nonexistent, and I finally feel happy and comfortable in my own skin! I smile! No weight gain (but I am gluten-free and an avid walker). I still have occasional panic attacks I take Xanax for, but this med has made them minimal. It has helped my head-to-toe pain from depression as well. I get up at 6 am every day and not sleeping all day like some have said. I work a full-time job and take care of kids with no side effects at 5 mg."

• Sel...
• Taken for 1 to 2 years
• April 24, 2023

Olanzapine "I have real events and false memory OCD, as well as GAD. My thoughts were running wild, I couldn't sleep more than 4 hours, and I was constantly giving in to my compulsions. After being hospitalized, I was prescribed Zyprexa. It worked almost immediately. That night, I was finally able to sleep a whole night, I got my appetite back, and my anxiety/thoughts were finally dampened to where I could function. I was on 2.5 mg, now up to 5 mg. Thank God for Zyprexa."

• Row...
• Taken for 1 to 6 months
• November 27, 2015

Olanzapine "I was prescribed Zyprexa as a one-pill cure for my OCD, insomnia, anxiety, and manic mood disorder. I am steadily increasing the Zyprexa dosage, starting with 2.5mg. At 5mg, I can state that my OCD is practically gone. I still have the desire to keep things orderly, but I am not getting frustrated or angry. I can now leave things to do for another day without obsessing over and over in my mind. No changes for the insomnia or anxiety at this dosage. I will post as the dosage increases and the symptoms are relieved. I have no negative effects to report at 5mg Zyprexa."

• dor...
• Taken for 6 months to 1 year
• February 9, 2019

"Coerced to take this; gave me permanent anhedonia (inability to feel pleasure). Avoid. I'd avoid this whole class of medications, to be honest with you. If you're in the throes of a violent psychotic episode, take one of the newer ones (Vraylar, Rexulti) that don't totally block dopamine. If you're not psychotic, acknowledge that taking these may sabotage your brain and ruin your life."

• Anx...
• Taken for 1 to 6 months
• January 13, 2024

"I was prescribed Olanzapine 5mg along with Paroxetine 20mg while being at the mental care hospital for severe and devastating GAD, OCD, insomnia, tachycardia, and panic disorder, along with severe weight loss. My OCD subsided as well as my insomnia. I was sleeping a lot, but this gave me relief. I put on 10 pounds in a month, but it was suitable at that point. It did make me hungry. In my experience, this drug helped in getting my anxiety and OCD under control along with SSRI. I stopped it 2 months after starting it as it was no longer needed and did NOT experience withdrawal. I would not give this a 10 as the effects on appetite and weight can be hard to manage, but overall I have to admit that Olanzapine helped tremendously in a moment of my life where I desperately needed it."

• Ros...
• Taken for less than 1 month
• March 27, 2023

"I have been diagnosed with BPD, OCD, anxiety disorder, and PTSD due to childhood trauma, grief, finding my mother dead, IPV, and sexual assault. Past doctors have made mistakes with my medications by pushing the milligrams up so much that it very nearly caused me serotonin syndrome. Be aware that some antidepressants are related to each other, and they caused me bad reactions, i.e., sertraline is another name for Seroxat. Paroxetine made my OCD worse, and I started pulling out my own hair, etc. For many years, these pills have caused me to feel ‘speedy’, I couldn’t sit still, chewing my lips and gums to shreds. Recently, I was put on 5 mg of olanzapine at night via my psychologist, and I felt a difference after the second pill. It helps me get to sleep, I feel more rested, comfortable, and relaxed. Neighbor conflicts don’t affect me as much, I’m not getting angry or weeping. Good for perimenopause."

• Son...
• September 1, 2016

"I'm a 34-year-old female who has obsessive thoughts about getting cancer. I have been battling OCD since I was 14, and this med has been a life changer. Although I still have thoughts, I don't freak myself out half as bad. I sleep like a baby, too! I have gained weight but am losing it now. 8 pounds total."

• Cor...
• August 9, 2009

Olanzapine "I was prescribed Zyprexa to treat my Obsessive Compulsive Disorder. I will say that my OCD behaviors were considerably helped, but the side effects were far too great for me. Thankfully, I'm a teacher and it was summer vacation because I couldn't wake up before 1 PM (granted, I do tend to sleep late in the summer, but not that late), and when I could finally pull myself out of bed, all I would be able to do until around 7 PM was lie on the couch with the posture of overcooked spaghetti, except when I was eating non-stop. The cravings were insatiable. I've always been very thin, but in that one summer I gained around 20 pounds. I had to switch medicines."

• Bee...
• Taken for 1 to 6 months
• September 6, 2018

"Have run the gamut of antidepressants for the last twenty-eight years and thought that I was as un-depressed as I would ever be. I take Wellbutrin and Prozac. But after I went Rambo on neighbors down the road, my physician added 7.5 mg of Zyprexa at night. For the first time, I actually felt happy for no reason. I still have bad days, but they are fewer. Side effects are minimal. I sleep better. I wish that the neighbors down the road would take a happy pill too and just chill."

• rlo...
• Taken for 1 to 6 months
• January 26, 2022

"I've been on 5 mg of olanzapine (planning to increase it to 10 mg) for around four months, and it has completely eliminated insomnia and greatly reduced the symptoms of OCD. I'm experiencing no side effects."

• Lil...
• Taken for less than 1 month
• August 3, 2024

"I had heavy and severe OCD, anxiety, panic attacks, delusion, derealization, and I couldn't take it anymore. Then the doctor prescribed me Olanzapine 5 mg/day. In 3 days I was feeling like my old self and happier. My thoughts were regular thoughts, nothing crazy, it completely stopped the ruminating thoughts with which I was physically/mentally exhausted before taking Zyprexa. Yes, you will feel hungry more, but for the time being, it’s worth having this side effect. You can watch your weight gain by drinking lots of water and exercising. I feel good knowing there is this drug when I go down again in the future."

• OsK...
• Taken for 2 to 5 years
• December 1, 2015

"I was on Zyprexa for a good two years because of intrusive thoughts ranging from sexual violence all the way to OCD, and I can say I mostly recovered thanks to these pills (which I took on the go in times of need and before going to sleep at 10 mg in the beginning) and a LOT of therapy. The downside is that I gained about 50 pounds (still trying to lose it after three months off medication), and I was just tired all the time, easily slept 14 hours uninterrupted. But it did help tremendously with the bad thoughts and the compulsions."

• Anonymous
• March 12, 2015

"Been on and off olanzapine for 15 years. Varying doses. As high as 15 mg per day, currently on 2.5 mg per day. Dose wonders to reduce voices, anxiety, OCD thoughts, and I sleep like a log. On the downside, I'm way less creative and energetic. I have put on huge amounts of weight in the past, but when I came off the med, the weight disappeared quickly. Now I can control weight gain by simply not eating processed foods and carbs. No carbs mean no olanzapine food cravings. I'm still able to eat fruit sugars with no problems. I just eat lots of proteins and vegetables. One major concern is my memory isn't as good, I used to be super sharp, and I can't think as clearly nor process complicated concepts. Overall though, it saved my life."

• Cdw...
• Taken for 1 to 2 years
• December 3, 2020

"I started olanzapine at 10 mg for OCD. Now I take 7.5 mg because it is so sedating. I plan on going down to 5 mg at my next doctor visit. Positives about this drug are it calms you down, helps you sleep, and completely heals your mind and body from stress/anxiety. Negatives about this drug are it will 100% make you gain weight when you first start it, BUT you can control it and lose it with low-carb dieting and running. Also, it has caused my hair to thin out, but I take hair biotin gummies now to help with that. Overall, I'd say this is about an 8 out of 10 just due to it having some negative side effects. But it has very much helped me. I'm 25 and was 80 pounds when I started it, now I weigh 107. So about 27ish pounds of weight I put on. Hoping when I go down to 5 mg I will be able to lose some, and my hair may fluff back up."

• Anonymous
• December 23, 2011

Olanzapine "Zyprexa helped with my obsessive-compulsive disorder. It also relieved the depression greatly. Weight gain is a bad side effect from this medicine (taking 10 mg daily). Gained 16 pounds in 2 months. The nights are better, just longer (around 11 hours every night)."

• Gig...
• Taken for 6 months to 1 year
• August 3, 2021

"I was originally prescribed 10 mg olanzapine to treat extreme mania caused by complications with pregnancy, antidepressants, and bipolar disorder. At first, it completely knocked me out at night, I slept a lot during the day, and I also gained 30 pounds in a short time. Since the extreme mania eventually passed, I stopped taking it without consulting my doctor. After that, foods and smells became unappealing and would make me gag. My long-term OCD came back full force. After consulting with my doctor, I started taking 5 mg instead. Now my OCD is almost completely gone, I’ve lost weight, I’m not depressed, I sleep well, and I have a lot more energy than I did taking 10 mg—would not recommend going that high unless you really need to be on an antipsychotic. I’ve noticed a drop in creativity, but that’s better than suffering, in my opinion."

• har...
• July 18, 2016

"I have been on this drug for 4 months. This drug has been a nightmare. I am on 15 mg. Soon after taking the drug at night, I start feeling clumsy, change in walking, balance difficulty, difficulty in speaking, shuffling in walks, felt complete numbness, and feel even more angry and want to throw things across the room. I feel out of control."

• Tmo...
• February 22, 2017

"I was put on this drug for my OCD and to help me gain weight because I was very thin. It did work and helped those things, but it also caused extreme constipation. That's why I got off of it. Within a few days of being off the drug, I started to have no appetite, and all food was disgusting to me. I never have had this problem in my life, I was always a big fan of food and would practically eat anything. Now it is hard for me to get enough calories in a day because I am disgusted by everything. I'll actually gag on foods now that I had no problem with prior to taking this medication. It has been many months since I got off of it, and no change. I would strongly recommend that you do not take this medication. It has been a nightmare. I am not writing this to be a jerk, I really want to warn people of what it can do so it doesn't happen to others. At the very least, consult with your doctor about this med. I have been on many different medications in my life, and this one is by far the worst in terms of getting off of it."

• Sav...
• Taken for 1 to 6 months
• September 8, 2024

"I tried for about a year to find something that would help, none of the meds I tried over the course of the year even touched my OCD symptoms - primarily real event OCD. Finally, the doctor decided to try antipsychotics, said Olanzapine was the best one to start off with. Within about a week, I had significantly reduced symptoms, and about a month later, I was about 70% back to normal. This medication worked like magic. The drowsiness was tough the first couple of days/week, but I adjusted and am back to waking up around 6:30 am without any drowsiness at all. I'm on 2.5 mg now, will move up to 5 mg plus samidorphan (Lybalvi) next week. It definitely increased my appetite, but I expect that to be tempered once I go on the Lybalvi."

• squ...
• Taken for less than 1 month
• December 3, 2024

"It's only been a week. I'm sure there'll be many twists to come. But I've suffered from OCD and depression, etc., since I was 9, and I'm now 49, and this is the first time I can feel a medicine working like this. Benzodiazepines and beta blockers work, of course, and Prozac clearly provides some help, given my disastrous attempt to come off it. But this gave me an overnight sense of peace and moral certainty that hasn't gone away. It hasn't helped my tics or need to pull certain muscles, but I feel cautiously optimistic. I can function at this level of distraction, which, given my recent condition, is remarkable. And I'm only taking it every second night. Of course, I must avoid driving. And (I'm male) my sexual performance immediately diminished. But that was quickly followed by sexual need, and since there's just me, that's more than tolerable. I'm definitely optimistic."

• Anonymous
• October 13, 2022

"This medication is a miracle for OCD, was on 5 mg, now increased it to 10 mg, it saved my life."

• Anonymous
• Taken for 5 to 10 years
• June 14, 2020

"At 10 mg, olanzapine completely cured my panic attack, OCD, and depression. I take it with 20 mg vilazodone. Godsend!"

• use...
• Taken for 6 months to 1 year
• May 2, 2023

"Good for anxiety and OCD, it's so incredible! I love it."

• Mar...
• Taken for less than 1 month
• August 10, 2022

"I was on olanzapine a long time ago, 5 mg for OCD. The worst antipsychotic I have ever taken! Since then, I have had weight problems. Before that, I ate whatever I wanted without gaining weight."