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Nitroglycerin for Anal Fissure and Fistula User Reviews (Page 2)

Brand names: Nitrostat, Nitro-Bid, Nitro-Dur, Rectiv, Nitrolingual Pumpspray, NitroMist, Nitrostat Tablets Minitran Nitro-Time GoNitro Deponit Nitro TD Patch-A …show all brand names

Nitroglycerin has an average rating of 7.2 out of 10 from a total of 38 reviews for the treatment of Anal Fissure and Fistula. 58% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Nitroglycerin

  • RMS_1...
  • March 10, 2017

Rectiv (nitroglycerin) "I've been on Rectiv for 2 weeks alongside an initial 10-day course of Cipro for a fistula. The Rectiv does cause an immediate headache within minutes of use, but after a few days it goes away, or you get used to it. I did notice relief of pain and swelling for a while until a sudden return of the pain, fistula and swelling! For no apparent reason and after no sudden changes in diet! Seeing my doctor tomorrow to try and determine another angle."

8 / 10
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3 Report
  • maste...
  • December 5, 2016

"My doctor had a compounding pharmacy make the equivalent for me. Only cost $22. I hear some of the people paying $500 for the prescription type? Anyway, before taking the medicine, I bled everyday. No pain but lots of blood for several years. After about 3 days the bleeding has stopped. As my doctor suggested, I continue to take the medicine for at least one month. Bottom line is that it let the fissure heal. Whether it will begin bleeding again after the medicine is stopped is another question. I hope not."

10 / 10
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3 Report
  • Jayde
  • Taken for 6 months to 1 year
  • May 14, 2022

Rectiv (nitroglycerin) "I had a fistula that was extremely painful for over a year and I needed surgery. I was prescribed Rectiv until the surgery and it helped within 30 min of using. It does cause severe headaches. I took ibuprofen right before using the ointment and I didn't get the headache again. I’ve found that Rectiv has also helped with tenesmus and hemorrhoid pain, although it isn’t usually prescribed for that, but it should be because it gives so much relief from those issues too."

10 / 10
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1 Report

Frequently asked questions

  • Atinob
  • Taken for 1 to 6 months
  • December 21, 2023

"I had a fissure for about 4 months when I saw a proctologist who prescribed Rectiv. I took Advil before using my first dose of Rectiv. Felt pressure and a mild headache. Took Advil before each Rectiv dose for the first 3 days, then tried without Advil and had no headache, just head pressure. Rectiv was effective in helping relieve some fissure pain. Prior to Rectiv, I had been taking oral pain meds every 4-6 hours for the fissure pain. Once I started using Rectiv, I was able to quit taking oral pain meds. But, unfortunately, after using Rectiv twice a day for 2 months, the fissure had not healed. (I wasn't surprised, as the studies done on Rectiv don't show a high success rate.) Ultimately, I had a sphincterotomy and removal of anal papilla (like internal skin tags caused by chronic fissure). I feel like this product might work for fissures that are not chronic and have no other complications."

5 / 10
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  • Analf...
  • Taken for less than 1 month
  • January 8, 2023

"Hello everyone, I am just now starting this medication. I took it for the first time last night and got horribly dizzy and felt terrible. I had a headache, nausea, all that. I ended up passing out and feeling normal when I got up the next day. I then tried it again but in a smaller dose today and so far, I have a headache but I don’t feel as bad as before. I have had an anal fissure for months now that bleeds every time I have a bowel motion. I am on stool softeners such as colace and Miralax and they seem to do the job to get me going. This all started from becoming super constipated a few months ago and forcing myself to poop. I really hope this medication works, as I am so sick of bleeding when I poop and tired of being so scared of it. I have had poops where I have almost no blood and I have had poops where I have a lot and it’s all over the poop itself (usually after a rectal exam). I am running out of hope and so sick of feeling this sense of worry and anxiety. Any tips?"

6 / 10
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  • Thief...
  • Taken for less than 1 month
  • August 18, 2019

Rectiv (nitroglycerin) "$696 for a cream that you can have made for $35. Ripoff and investigations into price fixing are in order!!"

1 / 10
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27 Report
  • msd
  • Taken for less than 1 month
  • July 17, 2012

Rectiv (nitroglycerin) "This is my first day of use...2nd application. I already have some relief where I got none from lidocaine and diltiazem."

8 / 10
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41 Report
  • Cmcn
  • Taken for less than 1 month
  • April 13, 2018

Rectiv (nitroglycerin) "One application as prescribed and I had a headache worsening over 3 hours, dizziness, and severe nausea. Ended up projectile vomiting. Scared to try again after experiencing these side effects."

1 / 10
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13 Report
  • Smilie
  • January 23, 2019

Rectiv (nitroglycerin) "The only thing I have found helpful in managing pain for severe hemorrhoids. Mild headache but tolerable given pain relief."

7 / 10
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9 Report
  • MsPai...
  • Taken for less than 1 month
  • October 2, 2018

Rectiv (nitroglycerin) "I was cold during the use, I had trembling and a light headache. I pray it works today is only day 1. $616.00 is alot of money as insurance did not cover which is horrible!"

7 / 10
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9 Report
  • someb...
  • Taken for 1 to 6 months
  • September 2, 2013

Rectiv (nitroglycerin) "Helped healing and did give me a headache but with repeated use the headaches went away soon. Overall Rectiv healed where nothing else helped, was worth the extra money."

8 / 10
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14 Report
  • Rothc...
  • July 24, 2013

Rectiv (nitroglycerin) "I used this medication just twice and had a severe headache for 3 days."

1 / 10
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11 Report
  • Bruce
  • Taken for less than 1 month
  • December 22, 2021

"Get the generic, $40.00 , the brand name was over $600.00 the pharmacist suggested to my doctor to prescription generic."

6 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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