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Naloxegol for Constipation, Drug Induced User Reviews (Page 4)

Brand names: Movantik

Naloxegol has an average rating of 4.6 out of 10 from a total of 149 reviews for the treatment of Constipation, Drug Induced. 34% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Naloxegol

  • jnla
  • Taken for less than 1 month
  • August 3, 2018

Movantik (naloxegol) "I've been on opioids for severe neck, and back pain (post-surgical) for more than 10 years. My gastro tested me on several drugs for constipation without success. Movatik was the least expensive and actually created a serious BM* within an hour. *Unfortunately, I experienced severe cramping, sweating, lightheadedness, exhaustion during and 1 hour after. I won't take Movantik every day due to cramping, sweating, weakness, but I can endure the pain once a week. * In all fairness I started Oxygenated Magnesium 07 (magnesium oxide) from a health shop- 3 at night. Mag 07 gave me one BM every 3 days. If I take 4 Mag 07 at night I have a decent BM the next day. Nowhere as significant as Movantik - but NO cramping sweats, etc. Mag 07 may well have set the stage for success with Movantik. I'll stay with Mag 07 and Movantik only once a week. For me, this is a magic combination."

7 / 10
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  • john
  • Taken for 1 to 6 months
  • October 25, 2015

Movantik (naloxegol) "Tried OTC and nothing worked. This worked quickly for me and has now continued to work for 5 weeks. Have read this board re side effects of others, but that has not been my experience. Read the label and talk to your doc -- looks like overall the experience of bad side effects is rare for patients who try this med, but talk about it with your doc -- for me this has worked where nothing else did."

10 / 10
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  • Molly...
  • June 19, 2016

Movantik (naloxegol) "I had been backed up literally for a year. Little drubs and drabs finally resorting to medical marijuana for pain, which did not work for my back pain, but somewhat stimulated my bowels not nearly as needed though just enough to break the agony. Was prescribed Movantik 25mg the first day I called 911 I thought something was severely wrong, it was the medicine doing it's job. after what seemed to be hours I was done until the next day and still pretty much the entire month. The 25mg was too strong so I take 12.5 It took a good month to finally adjust. Yes it hurt at first my bm was hard as a rock, but but after all is said and done I have a normal life, I can eat now too! Oh I am on 60 mg methadone 30mg hydro codons. Good Luck, it works."

9 / 10
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Frequently asked questions

  • Victo...
  • July 15, 2019

Movantik (naloxegol) "I have Raynaud's I have rheumethoid arthritis and I also have fibromyalgia therefore I'm prescribed opioids which everyone knows cause constipation. Movantiks is a life saver. Although it's says take one a day it's my belief it should only be taken when you can't go. Yes you will have cramps and sweating but ultimately this medicine works and I would recommend it to anyone."

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  • Billy
  • February 17, 2016

Movantik (naloxegol) "Ditto on every negative review I've read about this drug. I have had severe hemorrhoid swelling, burning and pain caused by the pressure of OIC. Although this drug was effective, the nightmare which preceded relief far outweigh ever taking this Big Pharma disaster. A mule couldn't tolerate this drug."

2 / 10
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Are you taking this medicine?

  • Lee
  • Taken for less than 1 month
  • April 2, 2017

Movantik (naloxegol) "Been on opiates for 10 years, broke my back had a fusion and have basically suffered since... talked to doc about the med the 1st two times I was amazed and sooo happy to have relief.. 3rd time I took it I was in withdrawal and couldn't go to work it was so bad :(. And I took it at night all 3 times. I'm so disappointed that it did this. I'm scared to take it again but now again back to being stopped up "

2 / 10
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  • WillDoo
  • August 23, 2015

Movantik (naloxegol) "I have Fibromyalgia, IBS-C, & worst of all, OIC. I took as prescribed one day.I got horrible pain and withdrawal symptoms, Gut gurgled for a couple hours in the morning. Then Zip, Nada, Nothing!! I was out after that. 2nd day too sick. I thought I should give it a 2nd try 2 wks later to make sure as I had high hopes I might get back some of my life. Same again but worse. Kept repeating symptoms at odd times for 4 days so far. I dread reliving withdrawals at bedtime. Docs should know Fibromyalgia is brain related disease so the med is crossing the blood barrier."

1 / 10
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  • Kival...
  • March 20, 2016

Movantik (naloxegol) "Taking it for three months and no bowel movements. I have one movement a month. I really need to poop . All this medicine does is make me felt sick.I take as it says and nothing happens .In between I take Mira lax still nothing. I get nausea vomiting alot of the time.Cramps I am so tired of being full of bowel. ."

1 / 10
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  • Smoot...
  • June 12, 2016

Movantik (naloxegol) "I take three hydrocodone a day and normally take a fiber supplement but find myself in trouble sometimes. Taking this in 25mg starts working in a few hours for me and last two days ending in nausea. I'm just not happy ruining two days so I found over the counter Magnesium Citrate that you drink and fast solution with no lasting nausea."

7 / 10
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  • Markman
  • Taken for less than 1 month
  • August 31, 2017

Movantik (naloxegol) "I have been taking opiates for ten years with the common side effect of constipation so my Dr prescribed Movantick. It worked but I really thought I was going to die . The cramps sweating head spinning and yes it cleanse you out with the worse smell ever experienced. If you use this be ready to suffer"

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  • Lauren
  • June 14, 2019

Movantik (naloxegol) "So I am on 70 mg of Methadone and have been on it for about 4 years. It is what causes my super horrible constipation. I tried 1 25mg Movantik for the first time yesterday. I took the pill at 1pm on an empty stomach when I got home from the pharmacy within 20 minutes I experienced the WORST stomach pain of my entire life. I immediately ran to the bathroom to try to go and couldn't. I had to go lay down immediately the pain was so intense. This was on and off for about an hour with no luck using the bathroom. Then about 1 hour and a half after taking the pill I was in full blown withdrawal. It was terrible I was crying and in so much pain. I was contemplating going to the hospital but I couldn't even walk and muster up the energy to go. I will NEVER take this medication again and I am very very upset my Dr did not warn me about these side affects. Had I known the risk I would have never even tried it."

1 / 10
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  • Knuck...
  • April 3, 2016

Movantik (naloxegol) "Before being put on movantik, I was only having a bowel movement some times 3 days, some time 5 or even hit 10 days once. Then I finally was put on movantik and now I'm going every 2 days and at least I'm not in pain when I go to the restroom."

9 / 10
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  • Moder...
  • December 23, 2019

Movantik (naloxegol) "I’m on 80 mg of methadone for opioid addiction and it’s worked brilliantly over the past 5.75 years. I ended up with bad methadone constipation—6 days no BM—and severe gas cramps. I read a lot of horror stories on this site and decided to start with half of a Movantik 25mg pill. Within 45 minutes, I had what would have been a decent sized BM—but I was going on 6 days of backup. I had very minimal cramping and no withdrawal symptoms to speak of. 8 hours later, I took the other 1/2–same result. I should note that I’ve been abstaining from taking my methadone for about 2 days hoping that a) it will help get things moving and b) it would lessen the severity of any withdrawal effects. I’m also on Wellbutrin, which has always worked as a buffer with withdrawal symptoms for me. I felt hardly any symptoms after my initial BM each time I took 1/2 a pill. I’d consider it a success—I feel way less blocked up."

8 / 10
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  • Back...
  • Taken for less than 1 month
  • May 2, 2017

Movantik (naloxegol) "Movantic does nothing more than put you in complete withdrawal. Eat a high fiber diet and you want be put thru HELL!! The pain docs will not tell you this when they prescribe it . And thats what the pharmaceutical co. don't want you to know!. No more of my money."

1 / 10
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  • Murray...
  • Taken for less than 1 month
  • December 31, 2016

Movantik (naloxegol) "I've been a chronic pain patient for 13 years. I currently take 128 mgs of Exalgo ER daily and 1-2, 8mg Dilaudid IR PRN no more than 6 tabs per day. I'm very familiar with constipation. When offered movantik 25mg every morning, I happily took it and within a day I was going easily but with a cramp pain. After a few more days, my guts started killing me so I stopped taking movantik. 11 days later severe constipation returns. Doc and I think since I've such a high tolerance my gut experienced physical withdrawal so today starting on ~8mg (~1/3 of 25mg tab) every 2-3 days. Anyone else taking Movantik similarly?"

7 / 10
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  • Charlie
  • Taken for less than 1 month
  • November 26, 2018

Movantik (naloxegol) "Let me tell u my movantik experience. Its terrible drug but it does help me use the bathroom but its not worth it. When I take it I have the worst stomach pains I have ever felt. I thought I was going to end up in the hospital. The pain was the worst stomach pain I have ever felt. I'm on 72 mg of methadone daily so its very hard to use the bathroom. While it did help with that the trade off will be the worst pain you have ever felt. If u ever saw the alien movie where they explode peoples stomachs to come alive thats how your stomach feels like it will explodes. Now IDK how many people experience these side effects but from what I read a lot do. If u can take it with out these side effects it deff will help u poop"

1 / 10
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  • aisll...
  • Taken for 1 to 6 months
  • August 11, 2017

Movantik (naloxegol) "Been taking Movantik for 2 1/2 months. At first it seemed to be working great, no side effects with normal daily bowl movements and was thrilled. Then last month, I noticed being nauseous about an hour after taking my morning dose (the literature recommends taking your dose in the morning, 1 hour before your first meal. Usually after eating, it resolved but then I started having random sudden severe cramping and nausea, cold soaking sweats, feeling extremely dizzy, and bad diarrhea ultimately. I didn't realize it was the movantik until I stopped it for a few days. Felt fine and then after restarting it happened all over. I guess that's withdrawal then? Had no idea but figured out it was the movantik causing the all the symptoms!"

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  • Teri
  • Taken for less than 1 month
  • March 31, 2018

Movantik (naloxegol) "I started taking 25mg yesterday after chronic back ups sometimes up to 2 weeks. Have had the script for 6 months but had the fear of withdrawal so I suffered and didn’t take it. That was dumb. I have stage 4 esophagus cancer which is the most painful cancer they say. So I take whatever I have to to stop it. It took 3 hours before I went and it was a good bit but only once. Going to do it again today and hopefully I will have the same results so I can get it all out of me. I cramped for about 4 hours after the bowel motion and had chills. Just fell asleep about two hours woke up and they were wearing off. No withdrawal symptoms yet so all and all a good drug. Don’t worry about withdrawal symptoms the good outweighed the bad. Will update about a week. Hope it helps you!"

8 / 10
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  • Zophini
  • June 14, 2016

Movantik (naloxegol) "I have been on Hydrocortisone for several years now and have had constipation for several years. I started taking Movantik for a month now and it has not worked at all. This has been a huge waste of money. I will have to talk to my doctor to find another way to relieve my constipation."

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  • Kathy
  • Taken for less than 1 month
  • May 19, 2019

Movantik (naloxegol) "Thirty minutes after taking Movantik I had a weird taste in my mouth, then started itching. It did work twice, but I feel like I have the flu, felt like it all day today. My pain has been awful today, despite my Morphine ER every 8 hours. Then it hit me, I think this medicine may have done something to my pain medication. It feels like withdrawal. Won’t be taking it anymore. I have enough bad days with this chronic pain from severe arthritis in cervical spine, and herniated discs, foraminal narrowing, Occipitalnyalgia, CMPS and Fibromyalgia, multiple joint osteoarthritis, and motility disorders on my Esophagus, along with Level C Esophagitis and Gastroparesis, etc. , etc. I don’t need this Movantik helping to add to my bad days. It did work and fast, but not at this cost."

2 / 10
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  • 2sadd...
  • Taken for 1 to 6 months
  • April 23, 2016

Movantik (naloxegol) "Extreme withdrawal symptoms. Chills, runny nose, cramps, pain, nausea, shakes, felt terrible. It worked well for first two days for a bowel movement but than stopped working as well. The bad side effects continued all the time I was on the drug (2 months ). My pain Dr. was surprised at my reaction to the drug as most of her patients handle it well. Insurance (UH) refused to pay for it after 2 months. My cost was going to be around 400 a month not worth it for me."

4 / 10
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  • Rodger...
  • Taken for less than 1 month
  • September 12, 2016

Movantik (naloxegol) "I just took my first dose and within an hour I went. But I've been sweating like anything,, I have terrible gas and bloating. Mentally i feel a little anxious but ok. I'm wondering how long this stuff blocks the receptors? Anyone?"

8 / 10
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  • Bronwyn
  • September 15, 2016

Movantik (naloxegol) "This did nothing to relieve my opioid induced constipation, but I kept taking it for 2 weeks. It made me sick. I had all the awful symptoms of opiate withdrawal and had to take extra medication for pain. It's been 2 weeks since I stopped taking Movantik and I still feel terrible."

1 / 10
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  • Chery...
  • January 21, 2018

Movantik (naloxegol) "Well it took a few days but my stool went from hard rocks that I'd had for many years to soft easy to release stool! I'm impressed, a bit of stomach flip flops going to ask for the lower dose. But I can finally poop!"

9 / 10
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  • sad2say
  • Taken for 1 to 2 years
  • October 16, 2016

Movantik (naloxegol) "Been taking Movantik 25mg for a year due to opioids. After taking it, within 10 minutes the gas starts. I have an abdominal hernia and get a painful fist size knot that I have to push on to get it moving. This drug is definitely not a sure thing. I still have to take flax oil capsules or stool softeners and sometimes even that doesn't help. I do not go without having a movement for more than two days and then I start with the suppositories and magnesium citrate. Before I got Rx for this drug I had constipation so bad I went to ER twice and that was the WORST enema experience. I thought I was going to die from my pain and the sweating and chills and trying to push. Eating apples daily helps when I can afford them!"

5 / 10
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19 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.