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Naloxegol User Reviews & Ratings (Page 3)

Brand names: Movantik

Naloxegol has an average rating of 4.9 out of 10 from a total of 270 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 48% reported a negative experience.

Reviews for Naloxegol

  • Range...
  • Taken for less than 1 month
  • August 23, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I have had constipation for months since taking Pain meds that I need for extreme back pain. The constipation has been so bad that it has made my back pain even worse. My doc gave me movantik and it has truly saved my life. It has regulated me, and made me regular again with hardly any straining. I cannot say enough good things about movantik and how it's been a game changer for me. Amazing!"

10 / 10
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  • Snowf...
  • September 5, 2020

Movantik (naloxegol) for Opioid-Induced Constipation "I have been on methadone for 9 years and I have extremely bad constipation from it. A few months ago I was in the ER for constipation related problems and the ER doctor gave me a prescription for Symproic. It worked great for awhile but didn't last long so my GI doctor prescribed me Movantik. I took it a little before bedtime, about 20 minutes later I started getting painful cramps and sweating, 15 minutes after that I had a small BM. The cramps lasted about 2 hours and by that time I was in full withdrawal. I was in withdrawal all night until I took my methadone the next morning, I wasn't able to get much sleep. The Movantik did work, and the cramps were bearable, but the withdrawal was too much for me, I do not think it is worth it to take this everyday, but if you don't mind the withdrawal this medication may be worth it to you."

5 / 10
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  • Conce...
  • October 21, 2019

Movantik (naloxegol) for Opioid-Induced Constipation "I took it very close to the same time I had taken my dose, within an hour I had a bowel movement but as soon as I did I began violently vomiting and explosive diarrhea, my hands and feet started going numb, I could not stop vomiting. I ended up in the ER via ambulance, I have never in my life been that ill. My bp jumped to 174/101, at the hospital they finally got me into triage and gave me zofran after an hour and a half it finally eased the nausea, had a terrible migraine to boot, finally once the nausea wore off I told my mom to take me to my house as I just wanted to lay down so I ended up walking out, dehydrated, migraine and all, went home and slept it off. The point of this comment is Movantik threw me into full blown withdrawal, I had no clue what this medication was, its noloxagol which is like noloxone, had I known I'd of never even touched it, so if you're on methadone think twice before taking it...has anyone on methadone maintenance that has taken this medicine experienced having a positive UDS because of movantik?"

10 / 10
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Frequently asked questions

  • Rik
  • October 12, 2019

Movantik (naloxegol) for Opioid-Induced Constipation "I found Movantik to have worked well for me. No pains just a reminder that if youfeel you need to go you and you need to move quick. Not diarrhea either. It normally takes from 1-2 hrs after taking it and I go 4-5 times usually but, not a bad experience only relief. It really cleans you out well and I feel great afterwards."

9 / 10
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  • PNL
  • May 21, 2017

Movantik (naloxegol) for Opioid-Induced Constipation "I hear a lot of horror stories regarding Movantic, but have not had any side effects; except for flatulence (gas), before going to the bathroom. I had a bowel impaction many years ago, from a L4-5 fusion; and was never told that the Vicodin could back my bowels up. Long and short, I had a bowel impaction, so badly; I go not go either way; and have to go to the ER, to have it removed. It was the worse pain that I EVER experienced in my life. I had an industrial accident around 6 years ago, and have had several surgeries. I live in chronic pain, and take pain medicine daily. I know how an impaction feels; and was heading for another ER visit. Movantic 25 mg was my answer; I wish it was available 15 years ago! A bowel impaction is a serious issue to deal with. When you’re constipated, you sit a lot on the toilet; and do a lot of pushing, which in turn, causes hemorrhoids. One thing that I have learned follows: I don’t sit on the toilet, until I feel the urge to expel my bowels. Sitting on the toilet causes a lot of pressure on the anus, and that in itself will cause hemorrhoids eventually. Let gravity do its job; as it was intended to do! Good Luck!"

10 / 10
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Are you taking this medicine?

  • Inten...
  • November 26, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I have read all of the reviews and am surprised at so many with serious side effects. That is a shame, because I have had remarkable success with Movantik. I have taken opioids for 8 years due to chronic and severe degenerative disk disease. I have taken fentanyl, morphine, oxycontin, hydromorphone, etc. The most current treatment is 24 mg of hydromorphone and 15mg of methadone per day. Constipation was a terrible side effect. I continually used OTC of all types, to little avail. At times, I would go 4-6 days w/o a BM. I had a BM on the first day I took 25mg of Movantik. No side effects. I take it once per day, and have a BM almost once per day. Sometime at the most every two days. Stools are not irregular. For me, a miracle drug"

10 / 10
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  • THIS...
  • Taken for less than 1 month
  • August 24, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I have taken opiates for many years primarily for back pain. I have OIC and tried numerous over the counter meds. For whatever reason the OTC laxatives, stool softeners and even miralax caused a horrible interaction with my methadone and I felt like I was poisoned until I stopped taking the OTC meds for about 5 days. Anyway...my Dr. recommended Movantik. I took the first 25 mg. pill and in about 2 hours I had a successful, somewhat easy bowel movement. About 15 minutes later what felt like 5 pounds of excrement came out. The first week was great. Here is where it gets awful...It wasn't until almost 2 full weeks into taking Movantik that I began having HORRIBLE Methadone withdrawal symptoms. I quit taking Movantik. NEVER AGAIN!!!"

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  • Chris
  • Taken for less than 1 month
  • September 22, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "I took my first dose yesterday morning at seven. Within thirty mins I had the worst cramps of my life! Was sweating puddles, bright red, sick as anything!!! My boyfriend had to drive me to the ER. It took benedryl, tordol, phetenol, phenagrin and a muscle relaxer that they had to put n my arm because they couldn't start an IV because my body was going through chills and dehydration from throwing up and horrible diarrhea. My stomach felt like it was tearing! I've been on methadone treatment for a little over two years. I do believe this medication sent me into the worst withdrawals of my life and that's how it unconstipates you. With my insurance I paid $30 and I won't be taking the other 29. I wouldn't take the chance of putting yourself through this."

1 / 10
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  • Jumping...
  • December 15, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I've been taking opioids for back pain for almost a year so I've been dealing with constipation for about the same length of time. I took Movantik last night for the first time and within an hour I had racing heart, shortness of breath, throbbing headache. Now 20 hours later I'm so irritable I could spit and can hardly think straight. 24 hours of anxiety and cramps and nausea! I'm so grateful to see these reviews because I don't feel alone and crazy."

2 / 10
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  • Joy
  • Taken for 1 to 6 months
  • October 23, 2018

Movantik (naloxegol) for Constipation, Drug Induced "My doctor had me try movantik because I have had 4 back surgeries all failed to relieve the pain so now I have to take pain med's just to feel half way human. I took the movantik and it worked really fast the first few times I took it and is still working not as fast but it works. Yes you can get cramps and shouldn't plan on doing much after taking it because u never know when it's going to kick it. I can handle the side effects and they can be painful. I am so glad that they finally got something that does what it says it's it's going to do. If you're uncomfortable because your backed up give it a try. Good luck to everyone that gives it a try."

8 / 10
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  • MB09
  • Taken for less than 1 month
  • December 24, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I lasted less than 3 weeks on Movantik my provider recommend! I ended up at up at ER because of the severe cramping, violent vomiting, bloating, nausea that had occurred. I'm being asked if I had ever had colitis or diverticulitis in the past which is a fat no! They had to put me on an IV bc of the dehydration. I've been off Movantik for a while and my GI is still irritated. Huge disappointment but I'd rather give natural birth to more children because it was a breeze compared to the experience I had with Movantik! Now it appears I have to seek a GI doc to deal with the after effects of being on it!"

1 / 10
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  • Lex
  • Taken for 1 to 6 months
  • August 17, 2015

Movantik (naloxegol) for Constipation, Drug Induced "Movantik works. Its somewhat inconsistent. Most days I can count on it. On an occasional day things don't move as well. On those days I supplement with a dulcolax suppository. Be advised that it may take 2-3 days for your system to get used to it. I felt a little tired and edgy. I think that's because it may induce some opiate withdrawal effects. It was only temporary and tolerable. These are all minor issues. Like I said, it works and that a big relief for an opiate user."

9 / 10
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  • Hope2...
  • October 31, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I get vilolently sick. I vomit, migraine, stomach cramps and lingering headache after 24 hour period.But am so desperate sometimes I put myself through it to feel better for a couple days after. I can't take it everyday or I would never be able to leave home because of side effects."

4 / 10
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  • RNStu...
  • July 22, 2015

Movantik (naloxegol) for Constipation, Drug Induced "My PM MD gave me samples after being constantly constipated for 2 years. Post L5-S1 disc replacement - 50mcg/hr q72h of Fentanyl and 10mg Oxycodone 6x day. The 1st time you take Movantik make sure you take it on a day off from work! I took it on a weekend, first thing in AM as the instructions say (1h before your 1st meal) and had a BM approx 4hrs later. I strongly suggest taking a stool softener - the BM was so wide from sitting in my intestines that I cut myself while going and bled (awful feeling). I tried taking every other day but gave me nausea the day of taking it and usually the day after, very painful cramping before during and after taking the pill and having a BM, and dec appetite. Will try Relistor inj next."

5 / 10
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  • Swagman
  • December 8, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Movantik worked like a charm for me - when used correctly, meaning no sooner than 2 hours after your last meal or 1 hour before your FIRST meal of the day. I suffer from pain due to nerve damage in lower back (S1 nerve root) after multiple surgeries and take oxy and percocet daily. When I did not follow that very simple schedule (by accident), ie, took it too close to my last meal, I had horrible bloating, pain, cramping and terrible diarreah. So I would GUESS that many of the negative reviews on here MAY be b/c of misuse."

8 / 10
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  • Chos
  • September 22, 2015

Movantik (naloxegol) for Constipation, Drug Induced "9-17-2015 The other reviews compel me to expand my comments. All Movantik does is land on the receptors in your stomach. These receptors are the ones opioid normally land on which makes it difficult to have a movement. I still have responsibility for what I eat and taking stool softeners and Senna tablets so my stool is soft. Otherwise I would be experiencing possible blockages. It is now 3 weeks and it works for me. But you have to pay attention. Also I am not a doctor. This just my experience."

9 / 10
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  • david...
  • October 18, 2015

Movantik (naloxegol) for Constipation, Drug Induced "what a joke of a med, I had terrible experience. I have been on oxycontin for 20 yrs and miralax everyday is wonderful, looks like a drug company is trying to recoup its development costs at patients expense, miralax is a miracle"

1 / 10
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  • Gamer...
  • Taken for 1 to 6 months
  • October 12, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I used samples of Relistor first. Although it caused massive abdominal pain for 30 minutes to an hour, it worked. Unfortunately it costs $2,000 a month & my insurance won't cover it. On to Movantik. Side effects are HORRIBLE. MAJOR withdrawal symptoms. Severe sweating, shaking, going from extremely hot to teeth chattering cold, yawning 50 times in a row, heart palpitations, massive abdominal pain, skin feels like it's crawling with sharp objects for hours. When I say hours..I mean 12-15 hours after my dose. Which was dropped from 25 mg to 12.5 mg. I have a bowel movement after taking about 20% of the time. I don't have a lot of choices though. In 2012, my colon ripped in half. I was in critical care, trying to not go through that hell again"

1 / 10
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  • SPIKE...
  • Taken for 1 to 6 months
  • July 28, 2015

Movantik (naloxegol) for Constipation, Drug Induced "As follow up to my previous post: after taking for approximately 6 weeks, I have the following side effects to report. Marked drowsiness for the first few weeks, now gone. Increased facial sweating, excessive sweat only from my face despite not being warm, though it is not always a daily occurance, it still continues. Lastly, I do very occasionally experience yawning an hour or so after taking my morning dose, usually after a sizeable bowel movement. Overall, this drug has GREATLY IMPROVED my quality of life, VERY effective w/ virtually no side effects. I do need to take a Bisacodyl lax.based on what I eat, but I HIGHLY recommend you try this if on long term opiates like me!!"

10 / 10
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  • Tresa
  • Taken for 1 to 6 months
  • November 16, 2018

Movantik (naloxegol) for Constipation, Drug Induced "My opioid constipation condition was really awful, because my Dr had not suggested a laxative at the time of writing prescriptions for hydrocodone, later oxycodone and percocet and I had been taking all of these for more than 2 months and had recently not had a bowel movement in 6 days. I was miserable and couldn't even sit up straight. Movantik was the 3rd prescribed laxative I tried, as the other 2 didn't work consistently. I am very grateful for Movantik. I take it on an empty stomach, first thing in the morning, very little cramping to speak of and (for me) within 2 to 4 hours, I have relief. If I miss a day, I notice I'm not able to go, but I simply make sure to takee it every morning for every day I'm taking opioids. I have definitely found that Movantik works for me."

8 / 10
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  • enwoo
  • October 3, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Talk about induced anxiety!!! I have NEVER felt so absolutely horrific as I did when using this medication. My doctor prescribed it one week after shoulder surgery when I was having severe stomach problems and constipation. I had already stopped taking percocet when I started taking it. And when I still wasn't pooping.....you guessed it, Doctor prescribed ADDITIONAL dosage! I was crying, in a state of panic, unable to sleep---I NEVER EVER want to feel this way again. After reading up on it, you are not supposed to take Movantik if you are NOT TAKING OPIODS!!!! Thank you for the medically induced anxiety horror show."

1 / 10
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  • DianaL
  • Taken for less than 1 month
  • September 22, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I have been on a small amount of Methadone 5mg twice daily. I can only go to the bathroom like 1 -2 times a week and then it's little hard balls. I took Movantik 25mg 1 time and went within 1 hour that would have been ok, but then a few minutes later my stomach hurt I mean realty hurt I was in tears then I went again, well I have gone so much it is pure water now and I will not take this again, I would be scared to try the 12.5mg. No withdrawal symptoms but the runs well the last time I had this that bad my kidneys were shutting down, so I fear for this, cannot eat or drink anything it runs right through me...be careful, I would try the lower amount first and see how that goes."

1 / 10
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  • BAD...
  • Taken for 6 months to 1 year
  • January 20, 2017

Movantik (naloxegol) for Constipation, Drug Induced "I tried Movantik and it worked very quick but made my stool pure blood. I had heard about that side effect before but never experienced it until then. It scared the hell out of me. I haven't taken it since."

1 / 10
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  • MaxQC
  • Taken for less than 1 month
  • November 29, 2015

Movantik (naloxegol) for Constipation, Drug Induced "This drug has been amazing for me over the past week that I've been taking it. My experience does not match the other reviews here in any way. I take Movantik in the early morning, and a few hours later I have a bowel movement %u2014 a normal bowel movement, not diarrhea. It's been very good for me."

10 / 10
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  • Bubble...
  • Taken for less than 1 month
  • November 22, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Been on opioids for a few years. Taking Miralax for constipation. Dr asked this month how my constipation was going. When I mentioned going twice a week she seemed to think that wasn't good so have me samples of movantik 25mg. Took first time before dinner and it worked great! Thought I would just take when feeling constipation. A few days later took a morning dose. I used the bathroom fine but afterwards Oh the Pain! The worst stabbing lower intestine pain I've ever felt. It came in waves for hours. Bent over thinking of going to the ER. I've been impacted before and had to go to the ER. So embrassing but would choose that over mavantix every time!"

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.