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Mirtazapine User Reviews & Ratings (Page 4)

Brand names: Remeron, Remeron SolTab

Mirtazapine has an average rating of 6.8 out of 10 from a total of 2,075 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Mirtazapine

Commonly mentioned side effects
  • Spr...
  • Taken for 2 to 5 years
  • June 9, 2020

For Insomnia "Yeah, I take mirtazapine for depression. It knocks me out every night (my dose is 45mg), but all night my brain is racing with weird dreams. I wake up, it feels like I haven't slept at all. I can sleep for 12 hours + easily and feel like rubbish when I get out of bed. I don't know if it's done anything for my depression/anxiety because I've been on them for a while. I take them with 30mg of diazepam a day. Yeah, I'm a total zombie. I always used to be slim, now I'm really bloated. I think they make you crave sugar. I regret starting taking them, definitely. Stay away if you can."

2 / 10
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  • Hol...
  • Taken for less than 1 month
  • January 15, 2025

For Anxiety "I have been happy and laid-back all my life, and a low iron deficiency caused severe anxiety, insomnia, and depression. I tried natural supplements and meditation, etc., but found myself asking the GP for help. I'm only on day 9, so I can't yet comment on serotonin levels, but I haven't had a panic attack, felt anxious, or been depressed since taking them! I too was searching the Internet looking at reviews and only taking on the bad ones, and I can say that after the first dose, I woke up feeling very strange and hated it but pushed through because now I feel more human again, and I can slowly feel my mood getting better, and I'm very early on. Don't be put off by the negative reviews, like I was - if you feel like I did, you've got nothing to lose, and I promise you it will get better."

10 / 10
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  • Bil...
  • November 5, 2014

For Insomnia "What it's supposed to do, it does very well. I was put on it for sleep and weight loss due to anxiety and depression after a stressful event in my life. I have struggled with insomnia for most of my adult life. What can I say? It was a literal life saver for me at the time. Gave me sleep and appetite back immediately and I turned around. I still take 7.5mg at night for sleep, appetite, and mood, and it works very well. For the first time in my life, I am at a healthy weight. That being said, it does not induce the crazy sweets cravings anymore. I just take it and go to bed. I sleep enough but do sometimes wake up feeling a bit groggy, but that usually goes away during the course of the day. All in all, a great medication that helped me immensely."

10 / 10
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Frequently asked questions

  • She...
  • January 25, 2015

For Insomnia "Was only sleeping 2-3 hours a night, some nights none at all. This on top of house, kids, and a stressful job, I was a walking mess. Started taking mirtazapine on my doctor's advice, and it has changed my life completely. No stress, and I sleep like a baby."

9 / 10
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  • Pip...
  • September 25, 2019

Mirtazapine for Major Depressive Disorder "Okay, been on this drug Remeron for depression for the longest time! Have been on so many different drugs, worked for a while, then nada, side effects, etc. My history, for 20 more years, is major depression and anxiety disorder. Partial personality disorder, it’s kicking in now, sorry. Remeron has been a Godsend to me for a long time. I, along with others, would highly recommend this."

10 / 10
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  • Mir...
  • Taken for 2 to 5 years
  • June 6, 2019

Mirtazapine for Depression "Prior to taking mirtazapine/Remeron, I had been on most SSRI and SNRI type drugs. I had chronic depression, suicidal ideation, and anxiety. Before taking Mirtazapine, I was starting to think all these drugs were a joke or a big con. I also didn't realize how ill I was until I started Mirtazapine, it's been a revelation! The first month, I went manic and had a few side effects. Since then, I've had the first three years of my life without any major episodes. My insomnia has basically disappeared, and I sleep like clockwork 2 hours after taking 30 mg. I can't describe just how grateful I am, it's not just changed my mood but also my whole frame of reference and outlook. It's something akin to changing the color of a lens on a camera, where once everything looked dark, now everything looks bright. Anxiety is the one area where it's been a help but has not solved the problem completely. My anxiety has improved, but I'm still trying to find a med that targets panic attacks and anxiety disorder."

8 / 10
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  • Joh...
  • April 22, 2014

For Insomnia "Most people should consider exercise and a better diet to help with sleep and also depression. Exercise can help. Also, get away from the TV and computer before sleep. Mirtazapine is probably the best sleep aid I have ever used. The more expensive sleep drugs are less effective, especially if you are worried and mind is racing. You can wake up groggy, but it sure beats not getting any sleep. I try to not rely on it that much, but it can be a godsend. It is also very inexpensive. I usually take the 15 mg tabs and cut them into quarters. The only reason I am posting this is hopefully it will help someone with insomnia. It is highly effective."

10 / 10
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  • Sch...
  • April 8, 2016

Mirtazapine for Depression "This medication is one of modern medicine's true miracles. I started taking it 7 months ago after a devastating benzo/opiate relapse, and I have suffered from MDD and insomnia for 19 years. During that time, I have literally tried everything - legal AND illegal. Thank God for this medicine. I did gain a ton of weight at first but consider it a small price to pay for high quality/quantity of sleep, energy, a positive mood, and an all-around 'good' feeling. Everyone reacts to medicine differently, don't give up. I am so thankful to have my sanity and my life back - all thanks to this medicine."

10 / 10
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  • Ama...
  • Taken for 1 to 6 months
  • February 16, 2014

For Insomnia "I was prescribed 15mg tablets to take one at night for sleep (or Doctor said 7.5mg was fine). I suffered from Anxiety (No Severe Phobias; more Obsessive Compulsive Disorder type personality), and Depression. This medicine affects your sleep feeling natural, not zombied. I sleep longer, it works better than heavy sedation medicines without being groggy, and I get through all the proper stages of sleep (I'd assume), as it has helped my depression MAJORLY & anxiety sufficient enough. I use to take Seroquel (for bedtime sleep 100mg), it zombies you and is long term very bad for your health. I tried about every SSRI & SNRI, and none seemed to help & only cause problems. I haven't felt this good in 8 years. Felt better immediately & GREAT after 2 weeks! Hope it helps you."

9 / 10
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  • ofr...
  • Taken for less than 1 month
  • July 26, 2015

For Anxiety "Was prescribed mirtazapine after citalopram failed to lift my depression and anxiety. I must say I was in a deep depression, you know, the place where everything is gloomy and hopeless and you just want to crawl into some cave and die. 15mg for the first couple of weeks nearly made me give up hope on this drug. The lethargy, hopelessness, and anxiety deepened. I am into my third week and I have upped the dose to 30mg as prescribed, and I feel completely different. The anxiety is reducing by the day, I feel hopeful, upbeat and for once in eight months, I wake up in the morning with a spring in my step. The zombie days seem to be disappearing. Mirtazapine is working for me and I hope it works for anyone who has started taking it."

9 / 10
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  • Iva...
  • Taken for 2 to 5 years
  • January 6, 2020

For Anxiety "I have experience with using mirtazapine for over 5 years, where I have gone on and off every time I relapsed into anxiety/depression. I noticed a few people blaming this drug because it did not help them on the first night with sleep. Don’t do that! In my experience, this drug helps with sleep, but not always on the first night. I find that sometimes it takes a week or longer before I sleep better when taking this medicine. Also, I have more energy from this medicine. It does not always make you drowsy. If you are depressed, it will give you energy but still let you sleep at night. Lower doses are better for sleep, 7.5-15mg is best for sleep. Don’t judge this drug after one day of no success."

8 / 10
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  • Anonymous
  • November 24, 2013

For Anxiety "I have been put on many different anxiety medicines for the past 20 years now, many with bad side effects. Then the doctor tried me on mirtazapine 3 years ago. I love this medicine. It is the only one that works for me with no side effects. I only weigh 100 lbs and take 45 mg a night with no side effects at all from the start of taking it 3 years ago. I sleep like a baby and wake up full of energy."

10 / 10
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  • SCA...
  • Taken for 2 to 5 years
  • May 22, 2020

For Insomnia "Been on Mirtazapine 30mg for 5 years. It works really great for my insomnia. I have not experienced any side effects such as weight gain. It helps me stay focused during the day too. I will say though, that I feel addicted to this medicine. I tried to stop taking it for 1 day (cold turkey) and I was doing really bad. So withdrawal after a long use has to be planned, while lowering the dose from 30mg to 15mg to 7.5mg."

6 / 10
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  • Peg...
  • Taken for less than 1 month
  • August 15, 2012

Mirtazapine for Anxiety "For many years I've been juggling medicines from Lexapro, Xanax, Zoloft, along with Lunesta for sleep. I had anxiety along with depression, couldn't sleep, and was losing weight. Three weeks ago, my doctor prescribed Remeron to me, and within a week, I was like a new person. Depression and anxiety lessened, and my sleep is great. This has been a miracle for me. Yes, I am gaining weight, but I needed to. My quality of life is so much better."

10 / 10
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  • Joh...
  • Taken for less than 1 month
  • April 24, 2025

For Major Depressive Disorder "Age 40. Gender: Male. Diag: Depression, anxiety, anger, irritability, OCD. Dose: 30 mg. Pros: -Higher libido (I always had good libido, but now it's at a puberty level. 'Getting there' only takes about 20 seconds now with my beautiful girlfriend, soon to be wife). -Erections are super firm. I used to need Viagra or Cialis to stay firm. -Better social skills and talking to strangers (Finally. Never could before). -Repetitive noises that used to bother me no longer bother me. -Less irritable, less angry, more happy. Better chemistry with my girlfriend, with no arguments (as we used to argue a lot). Cons: -Food cravings (Often times double portions. But it doesn't bother my weight as I exercise regularly.)"

10 / 10
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  • Flo...
  • November 2, 2016

Mirtazapine for Depression "Feeling fantastic, like myself again. Wanted to say I have not gained weight, in fact, I have LOST WEIGHT with this drug. My appetite increased but I needed it. I liked to skip breakfast and lunch most days to 'lose weight'. I only kept the fat on. With this newfound energy I'm experiencing, I'm more active and burning more calories. My increased appetite has prompted me to eat regular healthy meals and my metabolism has skyrocketed! I'm burning fat and building muscle. Just wanted to put in my 2 cents. A lot of people gained weight, I have not. If you watch what you eat and your portion size, plus exercise regularly, you shouldn't see an unwanted weight gain with this drug."

10 / 10
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  • rub...
  • Taken for 6 months to 1 year
  • September 7, 2020

Mirtazapine for Major Depressive Disorder "Mirtazapine took my depression away in as little as 5 days. It was great, now I can live. 5 months later I started having severe bouts of breathlessness. My Psych says it is not the drug, it is anxiety. I stopped the drug for three days and the symptom totally went away. I went back on it real quick cuz the depression came on fast. Doc put me on 0.5 mg clonazepam twice a day, but doesn't help the breathing. Anybody else have this breathlessness?"

9 / 10
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  • mar...
  • April 4, 2015

Mirtazapine for Depression "I've been taking this medication for approximately 3 years now. For all who are upset with the weight gain and sleepiness, it doesn't last forever. I think I gained about 10-15 lbs in my first few months, but I've managed to lose it all. Now I am only sleepy right after I take it (at bedtime) and I wake up feeling rested without the hangover. It's definitely levelled off my depression, and I feel normal. If you can get past the first few weeks, this medication is a life saver. I truly forgot that this medication even has side effects, since I've been on it so long. Also, I tried the SSRI/SNRI route first. On Zoloft, I would've made a great cast member for the Walking Dead. I've never felt more like a zombie. Remeron is the best!"

9 / 10
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  • Ann...
  • November 14, 2019

For Anxiety "I wanted to share my experience with Mirtazapine. About two months ago, I started having severe anxiety. I was terrified. I went to the doctor. She asked me if I had any family members that took antidepressants for anxiety, as I have had horrible side effects from SSRIs in the past and my mom takes Mirtazapine for anxiety. So, we decided to try 15mg at night. The first day, I was pretty tired but nothing too crazy, just felt like I hadn’t slept much. The first week, I had a few mild side effects like increased anxiety, feeling kind of out of it. Then after two weeks, I started to notice the anxiety being lifted. I’ve been on it for almost a month now and feel like myself again. I’ve gained maybe 2 pounds, but it’s well worth it! It does make me tired after about an hour of taking it, but I’m not a zombie. I just have an easier time falling asleep at night, which is a bonus! Highly recommend giving it a try, it could be well worth the wait!"

10 / 10
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  • Ger...
  • Taken for less than 1 month
  • October 25, 2020

Mirtazapine for Major Depressive Disorder "I'm on week 4 of mirtazapine 30mg and still feeling anxious. I have some really good days, so I think the tablet has started working, but then the next day I can be anxious all day long, which then disheartens me. I'm wondering whether to stick with it? Any experience would be welcome."

7 / 10
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  • Moe...
  • Taken for 1 to 6 months
  • February 23, 2021

For Anxiety "Mirtazapine has completely eliminated my chronic anxiety. I have PTSD and panic disorder with agoraphobia. The mirtazapine has given me the chance to live life without carrying around all of the toxic anxiety I have been suffering from for decades. I'm so glad that my doctor recommended this drug."

10 / 10
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  • sam...
  • Taken for 2 to 5 years
  • March 13, 2013

Mirtazapine for Insomnia "I have been on Remeron for 3.5 years. I started out on 15 mg and now currently on 30 mg. I have tried every sleep medication available. This is by far the best medication I have ever been on for sleep. Yes, I get the ravenous hunger, and it takes about 2 hours to make me sleepy. An hour after I take it is when the hunger kicks in, and I eat for the entire day before bed. I have gained about 30 lbs over the time being on it, but it has now tapered off, I hope! However, for me, sleep is so important, so it's a matter of what's more important, the perfect body or being so tired and depressed due to lack of sleep. If you start watching what you eat prior to bed, which I do now and wish I knew or realized this early on, you can help keep the weight."

9 / 10
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  • Sal...
  • Taken for less than 1 month
  • September 24, 2019

For Anxiety "Mirtazapine was the best decision my doctor ever made. After suffering from severe anxiety and constant panic attacks, I felt like I could cope no more. My doctor prescribed me 15mg of mirtazapine, and I could feel it working after a day. My anxiety has disappeared, and I haven’t had any panic attacks since. The only downside is I have been extremely hungry, but I would rather put on weight than feel like I did."

10 / 10
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  • she...
  • Taken for less than 1 month
  • July 13, 2023

For Anxiety "I wasn't sure whether to take this. Fluoxetine and propranolol put me in the hospital, but I decided to give it a try. The first week was amazing, I felt so much better. I'm currently in menopause and experiencing menopause anxiety, which I've never had before. I'm now on week 3 and have had a few bad days, but I understand it can take up to 6 weeks to work. All I can say is that if you've tried everything else and it hasn't worked, this antidepressant does. As for the weight gain and hunger, it only lasted the first week and I don't feel like that anymore. Compared to how I felt weeks ago, when I didn't want to be here, this medication has saved my life. I highly recommend it and don't plan on stopping it anytime soon."

10 / 10
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  • Kil...
  • Taken for less than 1 month
  • March 27, 2020

For Major Depressive Disorder "Before taking mirtazapine, I had been on sertraline for several months, with awful side effects. It turned me into an emotionless zombie. I didn't care about anything. They took me off when it triggered a hypomanic episode at 100mg. Mirtazapine compared to sertraline is night and day. This drug is wonderful. I started out at 7.5mg and had no initial side effects aside from grogginess after taking it (which went away after a few weeks) and dry mouth. Upped to 15mg after the first week. I sleep soundly (vivid sometimes crazy dreams but no nightmares) and wake up feeling energized. The 'dark cloud' of my depression started going away within the first couple of weeks. I have this newfound mental clarity... no more intrusive, negative thoughts and focusing on the horrible things of my past. I feel motivated and productive and joy in doing things again. I have not yet noticed any change in appetite or weight gain. Overall, mirtazapine has changed my life. I love living again!"

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.