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Methylnaltrexone for Constipation, Chronic User Reviews

Brand names: Relistor

Methylnaltrexone has an average rating of 4.5 out of 10 from a total of 4 reviews for the treatment of Constipation, Chronic. 50% of reviewers reported a positive experience, while 50% reported a negative experience.

Methylnaltrexone rating summary

4.5 average rating out of 10

4 ratings from 5 user reviews.

Compare all 21 medications used in the treatment of Constipation, Chronic.

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  • Anonymous
  • July 8, 2015

Relistor (methylnaltrexone) "Nothing yet, not helping, on 3rd day I took 3 shots, but still, not worked... I am on my 8th shot today... going back to docs in the morning... I hurt, I feel tight, bloated... it feels it could rupture at any time... God, the constipation feels like death. I am so full, I don't feel I can eat or drink."

1 / 10
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40 Report
  • cro...
  • Taken for less than 1 month
  • November 3, 2013

Relistor (methylnaltrexone) "My 1st 12 mg injection cramped me severely with sweating & nausea. Got to go about 20 mins later, had been 4 days. Have been on pain meds for 21 yrs and finally found this medicine. Getting ready for 2nd injection, hope the cramping ain't as bad as the first time."

8 / 10
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33 Report
  • Eda...
  • March 19, 2018

Relistor (methylnaltrexone) "I'm going on the 3rd month of usage, it absolutely helps with constipation. I have had every test possible, and they show no major problems. The gut still hurts every day. There's definitely a physical problem with the digestive tract. Cancer was ruled out, no heart problem, yet in so much pain and hard to pass stool without Relistor. Any doctors out there can give me any recommendations as to what to do next. I'm desperate. Thanks to all of you."

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22 Report

Frequently asked questions

  • Sto...
  • September 7, 2020

Relistor (methylnaltrexone) "I am prescribed Relistor shots once a day for opiate-caused constipation. I realize I'm supposed to take all meds as prescribed, but this is the only med I take that I take for it to work the best. I found taking it every day only lessens the effects of the drug, thus the benefits as well. What helps a great deal is if, when I wake, I drink a cup or two of some form of hot drink, be it coffee or hot water with lemon and honey, which is what I use. Then wait like 5 minutes and do your shot. When I went from everyday use, which within a month was basically totally ineffective, to using it three times a week with the hot drink before, I am a totally new person who can actually get out and live my life. I had no idea how much of life was being stolen away from me until I got a taste of it back! Oh, I also drink the hot liquid on the off days. Give it a couple of weeks to start regulating. Enjoying it! I hope others out there find this helpful. It's been a lifesaver for me."

8 / 10
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13 Report
  • Pea...
  • Taken for less than 1 month
  • July 31, 2019

Relistor (methylnaltrexone) "I have had chronic constipation due to taking methadone for severe nerve damage and my nerves now not working in my colon and stomach properly. I have been on opioids for over 26 years. From reading some of these reviews, I wonder if some of you may have similar issues and that may be why many meds may or may not work for you. You may want to check with your doctor about the possibilities. OIC is the first issue thought of, but in some cases, there may be more to it, so I have learned. I'm hoping this info can at least help someone. I have taken my first dose today of three 150 MG tabs 30 min before eating first thing in the AM. I will be starting out by taking this dose for 3 days in a row. I am hopeful because Movantik worked well more than not, however, it was always a violent clearing out of my system and the withdrawal side effects were unbearable for me, so I am a bit fearful of these side effects from Relistor. I will be back to share how or if this med works for me enough."

1 / 10
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15 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.