depo-subQ provera 104 for Endometriosis User Reviews

• cla...
• January 10, 2013

"I got on this as a teenager for my endometriosis. Besides spotting for the first four months, I have had no ill effects. No weight gain. In fact, it's hard to keep weight on. I got off of it to have my kids. Now I'm back on it. It's so much easier raising toddlers without cramps and random bleeding. I recommend it highly. Don't let bad experiences scare you. I actually had a horrible time with the pill. I love my Depo shots!"

• TN ...
• March 5, 2014

"I was hesitant to try this, but I really didn't want to have a hysterectomy. I've already had one ovary/tube out due to my endometriosis. I was recently diagnosed with also having adenomyosis now. It was Depo-subQ, Lupron, or a hysterectomy. I read so many terrible reviews that it had me nervous, but I tried it anyway. I've gained a few pounds, but am also 45 and lazy, so that may be the more likely culprit. My acne is actually gone. I've had no endometriosis symptoms. My hair is slightly thicker. For me, it's been a miracle. We're hoping to be able to have these results until menopause hits."

• nkb...
• Taken for 1 to 2 years
• February 8, 2014

"My doctor put me on Depo-Provera after laparoscopy for endometriosis. I had irregular periods after the first shot, and after the second, I remember I had one period that seemed to last for a month. This is a known side effect, and as promised, it went away after the third shot. I haven't had my period now in about a year. I also haven't had any debilitating endometriosis symptoms either. I think I gained about 5 lbs total, but then again, I'm also in my 40s, and that could simply be a part of aging. I am a big fan. It gave me nearly total relief after getting through the first 6 months."

• mis...
• Taken for 1 to 6 months
• January 12, 2014

"I have severe endometriosis and a lot of scar tissue from laparoscopic surgery four years ago when they removed two large cysts that were wrapped around my fallopian tube, which I lost. Then last year my right ovary hemorrhaged and I bled internally for two days. Two weeks ago I had a cyst rupture on my right side. I am SO done with being in pain. I've been in nonstop monthly HELL for the past four years! So I got back on the Depo-Provera shot. I took it when I was a teenager for two years for my endo pain. And I loved it. I am so glad to be back on it. I am also on a seizure medicine that makes birth control ineffective, but has no effect on the Depo shot, so that is another plus."

• Jud...
• March 6, 2015

"I've had endometriosis my whole life. Six surgeries. I was on Lupron 2x. Birth control pills. Finally, the depo was my last resort. The first time, it made me bleed every day for 7 months. I didn't give up on it. It made me gain weight because it increases your appetite, and you don't realize it until you go off of it. I still didn't give up. I've been on it now for 5 years, and I have joined Weight Watchers and increased exercise. I have not had a period in 5 years. I don't miss the agony, the pain, the hospital visits, being bedridden for 3 days a month. I love the Depo, and now I'm making progress with losing weight, so I'm happy."

• Cyt...
• Taken for less than 1 month
• June 6, 2014

"I refused to get the shot because I had researched Depo for a paper in college, but it came down to Depo or severe anemia. So I received the shot, and the next morning I was praising Jesus because the shot got rid of the almost constant back pain I'd had for 2 years since delivering my twins. Doctors kept telling me it was a sprained muscle, only it never healed, now I believe it was endometriosis."

• Emm...
• Taken for 1 to 2 years
• January 23, 2019

"I have been on this for almost 2 years now, it was working great, no side effects, and also keeping my endometriosis under control (the main reason it’s all I can use). Suddenly, I started having large gushes of blood while not on a period with the depo-subQ Provera. I would spot for a few days, then stop, then a large gush, heavy enough to bleed through my oversize pad and my clothing. I have had many ultrasounds, MRIs, and still no answer to why this started after being on it for so long. If anyone else has experienced that, I would love to know if you have found a cure. I need the depo to help my endometriosis, so unfortunately, I can’t use any other form of birth control."

• Ckw...
• Taken for 6 months to 1 year
• May 6, 2016

"I have been on many birth control pills and hardly any of them were beneficial to me. I switched to this injection and I'm so happy I did. I started birth control when I was 15 bc my cramps were unbearable. Endometriosis runs in the fam. I also had bad acne, so I was trying to alleviate both of those issues. The depo shot didn't affect my acne in any way, but it has almost completely diminished my cramps. The first 3 months were rough. didn't bleed for a month and a half after getting it, but then I bled until it was time for my next shot. I got my second shot and didn't have my period for three months. It was awesome. Spotting around the due date for the next shot is normal. Oh, and the shots are painless. Stick through the rough first months!"

• Anonymous
• September 26, 2011

"I've only taken one shot, it has been somewhat of a last-ditch effort to provide some pain relief from endometriosis and polycystic ovaries. The first month was great, no pain and very little spotting. The second month has been horrible, I had a period for 2 1/2 weeks, and the other 1 1/2 I had spotting along with horrible (at times) pain that even Lortab won't fully control. The doctor gave me estrogen to stop bleeding, and that took a week. As of now, I am not taking another shot. I told my husband that I can feel this bad for free. If this third month goes okay, I may reconsider. I've tried everything, and it's bad... looks like hysterectomy is the next step."

• Nik...
• Taken for 6 months to 1 year
• August 1, 2020

"I have been having the depo injection as I have endometriosis. It has worked wonders for me. After the first two injections, I was spotting a lot, but after the third, it stopped my periods completely, which were so heavy and painful. The only downsides are when I first get the injection, I am really grumpy for the first few weeks. My sex drive is nowhere near as high as it used to be, and I have gained weight, which the doctors tell you will only happen if you eat more. I find this not to be true, I have been exercising more than I ever have and eat so healthy all of the time. No matter what I am doing, I can’t seem to lose the weight."

• Anonymous
• October 1, 2011

"I've had endometriosis for over 20 years and have had about enough of the pain and the accompanying anemia from blood loss. In the last 5 years, my blood loss from the endometriosis has increased tenfold, and I have developed severe iron deficiency anemia. My OB/GYN and I decided to try Depo again (last time was in the early 90s), and I had my first shot in July of 2011. August was HEAVEN! No period, and my iron levels tested almost normal. I was human again! Now it's September, and I have had a 'period' (in quotes, because it's more like a normal woman's period) for over 15 days, and I feel like I have been hit by a Mac truck. No endometriosis pain, but my iron levels are so low from bleeding that all I can do is sleep. When it works, it's fantastic."

• n17...
• April 9, 2015

"I was diagnosed with stage 4 endometriosis at 17 years old. After being on Lupron for 6 months, my doctor proceeded to put me on Depo for the rest of my life until I decide to have kids, and then back on the shot afterwards. I am now on my 5th shot and I've had horrible endometriosis pain (not cramps, very different pain) and have had my period for 2 weeks. I am not sure the Depo is working correctly with my body, but other than that, the previous shots have made almost all pain from my endometriosis go away."

• Ell...
• March 1, 2016

"Was on depo shot for 9 months. First, I had lighter periods, and the endometriosis pain was better. Second month, I had a light period, but it was all month. And then after that, the pain was less, and there was no bleeding. I started to gain weight. Almost 50 pounds. I already have back pain from a herniated disc, so I did not go and get my last shot. Endometriosis pain is back ten times worse. And I have been bleeding almost nonstop since September 2015, and it is now March 1, 2016. I'm gonna go back to the doctor and have a hysterectomy. I cannot stand the bleeding or the pain."

• She...
• Taken for 2 to 5 years
• August 27, 2015

"I started on the shot in 2013 to help with the pain from endometriosis. My cycle was pretty regular, but I was in constant pain. The first year went pretty good, with no side effects. After the first year, I started bleeding heavily and continued to for three months. I was put on estrogen, and the depot shot went from every twelve weeks to ten weeks. After three months of this, I underwent a uterine ablation. The bleeding stopped, but the pain from the endometriosis is still an everyday problem, and I have put on 45 lbs, my blood pressure has gone up. My doctor and I have decided the depot shot is no longer an option. The shot worked, I suggest monitoring your health while on it."

• Meg...
• April 5, 2015

"I started my first injection over a month ago for my severe endometriosis. The day after, I started noticing terrible mood swings, as did my family. I would get angry and freak out at the tiniest things. Usually cry over nothing. It lasted for about 4 weeks, and my moods have simmered down, but not as much as they should. He said to consider Zoloft because my hormone levels aren't normal, and I have anxiety. I have been spotting every day for the whole month and still notice some pain, but not as bad as it was before I started the injections. My ob-gyn said this was normal and assured me after the third injection this would go away. Hopefully, it does. I can now say I'm not living in hell 12 times a year."

• 456...
• Taken for 1 to 2 years
• December 6, 2022

"I got sick of the pill, the pill never helped with my cramps, and I had constant periods. For very heavy periods, I would have to change ultra tampons within an hour and a half. I have awful cramps, I’ve also passed over 20 kidney stones, and my cramps are still worse. Then I started depo, I want to cry, it has been amazing-no cramps, no periods, no suffering. I wish I had started in my teen life, it would have been so much easier. Also, if you have general joint pain to begin with, make sure you take your calcium and vitamin D! One year of taking it, my hip and femur started becoming very painful and feeling empty? Not sure how to describe the feeling. However, once I started taking calcium plus vitamin D regularly, it felt a lot better! (I also work a very, very labor-intensive job lifting over 150 pounds throughout the day, so I already have joint issues.) That was the only bad thing from the pill, it’s just been fantastic otherwise!"