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depo-subQ provera 104 for Endometriosis User Reviews

depo-subQ provera 104 has an average rating of 7.7 out of 10 from a total of 15 reviews for the treatment of Endometriosis. 67% of reviewers reported a positive experience, while 13% reported a negative experience.

depo-subQ provera 104 rating summary

7.7/10 average rating

15 ratings from 16 user reviews.

Compare all 63 medications used in the treatment of Endometriosis.

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Reviews for depo-subQ provera 104

  • clari...
  • January 10, 2013

"I got on this as a teenager for my endometriosis. Besides spotting for the first four months I have had no ill effects. No weight gain. In fact its hard to keep weight on. I got off of it to have my kids. Now I'm back on it. It's so much easier raising toddlers without cramps and random bleeding. I recommend it highly. Don't let bad experiences scare you. I actually had a horrible time with the pill. I love my Depo shots!"

10 / 10
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  • TN mom
  • March 5, 2014

"I was hesitant to try this but I really didn't want to have a hysterectomy. I've already had one ovary/tube out due to my endometriosis. I was recently diagnosed with also have adenomyosis now. It was Depo-subQ, Lupron or a hysterectomy. I read so many terrible reviews that it had me nervous but I tried it anyway. I've gained a few pounds but am also 45 and lazy so that may be the more likely culprit. My acne is actually gone. I've had no endometriosis symptoms. My hair is slightly thicker. For me it's been a miracle. We're hoping to be able to have these results until menopause hits."

9 / 10
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58 Report
  • nkb
  • Taken for 1 to 2 years
  • February 8, 2014

"My doctor put my on Depo-Provera after laproscopy for endometriosis. I had irregular periods after the first shot and after the second I remember I had one period that seemed to last for a month. This is a known side effect and as promised it went away after the third shot. I haven't had my period now in about a year. I also haven't had any debilitating endometriosis symptoms either. I think I gained about 5 lbs total but then again I'm also in my 40s and that could simply be a part of aging. I am a big fan. It gave me nearly total relief after getting through the first 6 months."

9 / 10
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48 Report

Frequently asked questions

  • missb...
  • Taken for 1 to 6 months
  • January 12, 2014

"I have severe endometriosis and a lot of scar tissue from laparoscopic surgery four years ago when they removed two large cysts that were wrapped around my fallopian tube, which I lost. Then last year my right ovary hemorrhaged and I bled internally for two days, two weeks ago I had a cyst rupture on my ride side. I am SO done with being in pain. I've been in non stop monthly HELL for the past 4 years! So I got back on the Depo-Provera shot. I took it when I was a teenager for two years for my endo pain. And I loved it. I am so glad to be back on it. I am also on a seizure medicine that makes birth control ineffective, but has no effect on the Depo shot, so that is another plus."

10 / 10
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48 Report
  • Judii
  • March 6, 2015

"I've had endometriosis my whole life... Six surgeries.. I was on Lupron 2x.... Birth control pills.... Finally the depo was my last resort.... The first time it made me bleed everyday for 7 months... I didn't give up on it... It made me gain weight because it increases your appetite and u don't realize it until u go off of it.... I still didn't give up... I've been on it now for 5 years and I have joined weight watchers and increased excercise..... I have not had a period in 5 years..... I don't miss the agony ... The pain... The hospital visits.... Being bed ridden for 3 days a month.... I love the Depo...and now I'm making progress with losing weight so I'm happy..."

10 / 10
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32 Report

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  • Cytog...
  • Taken for less than 1 month
  • June 6, 2014

"I refused to get the shot because I had researched Depo for a paper in college, but it came down to Depo or severe anemia. So I received the shot and the next morning I was praising Jesus because the shot got rid of the almost constant back pain I'd had for 2 years since delivering my twins. Doctors kept telling me it was a sprained muscle only it never healed, now I believe it was endometriosis."

10 / 10
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33 Report
  • Emmamp
  • Taken for 1 to 2 years
  • January 23, 2019

"I have been on this for almost 2 years now, it was working great no side effects and also keeping my endometriosis under control (the main reason it’s all I can use). Suddenly I started having large gushes of blood while not on a period with the depo-subQ provera . I would spot for a few days then stop then a large gush, heavy enough to bleed through my oversize pad and my clothing. I have had many ultra sounds, MRI, and still no answer to why this started after being on it for so long. If anyone else has experienced that I would love to know if you have found a cure. I need the depo to help my endometriosis so unfortunately I can’t use any other form of birth control."

7 / 10
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17 Report
  • Ckw
  • Taken for 6 months to 1 year
  • May 6, 2016

"I have been on MANY birth control pills and hardly any of them were beneficial to me. I switched to this injection and I'm so happy I did. I started birth control when I was 15 bc my cramps were unbearable. Endometriosis runs in the fam. I also had bad acne so I was trying to alleviate both of those issues. The depo shot didn't affect my acne in any way but it has almost completely diminished my cramps. The first 3 months were rough. didn't bleed for a month and 1/2 after getting it, but then I bled until it was time for my next shot. I got my second shot and didn't have my period for three months. It was AWESOME. Spotting around the due date for next shot is normal. Oh and the shots are painless. Stick through the rough first months!"

9 / 10
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18 Report
  • Anonymous
  • September 26, 2011

"I've only taken one shot, it has been somewhat of a last ditch effort to provide some pain relief from endometriosis and polycystic ovaries. The first month was great, no pain and very little spotting. The second month has been horrible, I had a period for 2 1/2 weeks and the other 1 1/2 I had spotting along with horrible (at times) pain that even Lortab won't fully control. Doctor gave me estrogen to stop bleeding and that took a week. As of now I am not taking another shot. I told my husband that I can feel this bad for free. If this third month goes okay I may reconsider. I've tried everything and its bad...looks like hysterectomy is next step."

1 / 10
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19 Report
  • Niki
  • Taken for 6 months to 1 year
  • August 1, 2020

"I have been having the depo injection as I have endometriosis. It has worked wonders for me, after the first 2 injections I was spotting a lot, but after the third it stopped my periods completely- which were so heavy and painful. The only down sides are when I first get the injection I am really grumpy for the first few weeks. My sex drive is no where near as high as it used to be and I have gained weight, which the doctors tell you will only happen if you eat more. I find this not to be true, I have been exercising more than I ever have and eat so healthy all of the time. No matter what I am doing I can’t seem to loose the weight."

8 / 10
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7 Report
  • Anonymous
  • October 1, 2011

"I've had endometriosis for over 20 years and have had about enough of the pain and the accompanying anemia from blood loss. In the last 5 years my blood loss from the endometriosis has increased tenfold and I have developed severe iron deficiency anemia. My OB/GYN and I decided to try Depo again (last time was in the early 90s) and I had my first shot in July of 2011. August was HEAVEN! No period and my iron levels tested almost normal. I was human again! Now it's September and I have had a "period" (in quotes, because it's more like a normal woman's period) for over 15 days and I feel like I have been hit by a Mac truck. No endometriosis pain, but my iron levels are so low from bleeding that all I can do is sleep. When it works, it's fantastic."

8 / 10
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16 Report
  • Ellis...
  • March 1, 2016

"Was on depo shot for 9 months. First I had lighter periods and the endometriosis pain was better. Second month I had light period but it was all month. And then after that the pain was less and there was no bleeding. I started to gain weight. Almost 50 pounds. I already have back pain from herniated disk so I did not go and get my last shot. Endometriosis pain is back ten times worse. And I have been bleeding almost nonstop since September 2015 and it is now March 1 2016. I'm gonna go back to the Dr and have a hysterectomy. I can not stand the bleeding or the pain"

1 / 10
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9 Report
  • n1723
  • April 9, 2015

"I was diagnosed with stage 4 endometriosis at 17 years old. After being on Lupron for 6 months, my doctor proceeded to put me on Depo for the rest of my life until I decide to have kids, and then back on the shot afterwards. I am now on my 5th shot and I've had horrible endometriosis pain(not cramps, very different pain) and have had my period for 2 weeks. I am not sure the Depo is working correctly with my body but other than that, the previous shots have made almost all pain from my endometriosis go away."

7 / 10
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9 Report
  • Shell...
  • Taken for 2 to 5 years
  • August 27, 2015

"I started on the shot in 2013 to help with the pain from endometriosis my cycle was pretty regular but I was in constant pain. The first year went pretty good with no side effects after the first year I started bleeding heavily and continued to for three months I was put on estrogen and the depot shot went from every twelve weeks to ten weeks after three months of this I under went a uterine ablation the bleeding stopped but the pain from the endometriosis is still an every day problem and I have put on 45lbs my blood pressure has went up. My doctor and I have decided the depot shot is no longer an option. the shot worked I suggest monitoring your health while on it."

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  • Megap...
  • April 5, 2015

"I started my first injection over a month ago for my severe endometriosis. The day after I started noticing terrible mood swings, as did my family. I would get angry and freak out at the tiniest things. Usually cry over nothing. It lasted for about 4 weeks and my moods have simmered down, but not as much as they should. He said to consider Zoloft, because my hormone levels aren't normal and I have anxiety. I have been spotting everyday for the whole month, and still notice some pain, but not as bad as it was before I started the injections. My obg said this was normal, and assured me after the third injection this would go away. Hopefully it does. I can now say I'm not living in hell 12 times a year."

7 / 10
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8 Report
  • 456732
  • Taken for 1 to 2 years
  • December 6, 2022

"I got sick of the pill, the pill never helped with my cramps and I had constant periods. For very heavy periods would have to change ultra tampons within an hour and a half. I have awful cramps, I’ve also passed over 20 kidney stones and my cramps are still worse. Then I started depo, I want to cry it has been amazing no cramps, no periods, no suffering. I wish I had started in my teen life would have been so much easier. Also if you have general joint pain to begin with, make sure you take your calcium and vitamin D!!! One year of taking it my hip and femur started becoming very painful and feeling empty? Not sure how to describe the feeling. However, once I started taking calcium plus vitamin d regularly it felt a lot better! (I also work a very very labor intensive job lifting over 150 pounds throughout the day so I already have joint issues) that was the only bad thing from the pill it’s just been fantastic otherwise!!!!"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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