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Lifitegrast ophthalmic User Reviews & Ratings (Page 2)

Brand names: Xiidra

Lifitegrast ophthalmic has an average rating of 3.8 out of 10 from a total of 304 reviews on Drugs.com. 26% of reviewers reported a positive experience, while 55% reported a negative experience.

Reviews for Lifitegrast ophthalmic

  • Eyes
  • January 30, 2021

Xiidra (lifitegrast) for Dry Eye Disease "These eye drops are extremely dangerous. Caused me to have a horrible sore throat, swollen lymph nodes on the sides of my neck, pain in my ears, and blurred vision. This will be one of those medications that they recall because of the damaging side effects. Not on the market long enough. This should have never been approved by the FDA. In spite of the money I paid for this over priced drug, I threw it all away. Bad stuff."

1 / 10
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  • Rosie
  • Taken for less than 1 month
  • February 26, 2021

Xiidra (lifitegrast) for Dry Eye Disease "WARNING! Be very careful. First time use one tiny drop in one eye to see how it affects you. I had used it for 20 days and it helped my dry eye but after a week I developed terrible side effects: sinus and ear infection, severe dizziness. I didn't make the connection until too late and ended up in the hospital after a severe dizzy spell. All tests were negative. Two months later my dry eye came back so I thought I could use it for just a couple of days. I tried one drop. I was up all night with burning, blurry eyes using eye wash and artificial tears. Nothing helped.This morning my eyes are so red and irritated. Praying they recover soon. Will never use again."

1 / 10
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  • Laurie
  • Taken for less than 1 month
  • April 9, 2023

Xiidra (lifitegrast) for Dry Eye Disease "Xiidra was NOT approved in Europe due to the risks outweighing the benefits. Please try something else to treat dry eyes and stay away from Xiidra. I wish I would’ve read these reviews before. I did not see a benefit from using Xiidra and noticed my eyes became watery and teary. I had to frequently wipe my tears which was never a problem before. On the second week of using Xiidra, the inner corner of my eyes felt sore and when I touched the area I felt a bump that was tender. It seemed that my lacrimal sac was inflamed which explained the teary eyes. I also began feeling nauseous the same day and threw up at night. I am a young healthy adult that goes years without getting sick. The last time I threw up was when I was a kid. Threw away the rest of Xiidra the next day. What are they putting in these eye drops?"

1 / 10
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Frequently asked questions

  • Conce...
  • Taken for 1 to 6 months
  • February 5, 2021

Xiidra (lifitegrast) for Dry Eye Disease "I started using Xiidra 3 months ago 1 drop both eyes twice daily. It burns on application and I have noticed that my vision acuity has changed for the worse. My eyes frequently itch and I have developed an enlarged lymph node in my neck that is hard and tender to touch. I have also developed a scalp irritation (dermatitis) that extends ear to ear from the back of my neck hair line up to the middle of my scalp. It itches horribly and wakes me up in the middle of the night. Is Xiidra causing these issues ? I don't know. I do know that I did not have these symptoms prior to starting Xiidra. My dry eye issues have improved somewhat but not enough to continue using Xiidra."

1 / 10
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  • Jae
  • Taken for 1 to 2 years
  • July 17, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have used Xiidra for almost 2 years. It helped with the dry eye for a few months but in the 2 years of using it my vision became worse and blurry. I was prescribed a stronger prescription for my contacts. My eyes also became puffy. I didn't know what was causing the bags under my eyes and puffiness at the top. I even got fillers put in the bags were so bad. I stopped Xiidra about a week ago because I needed a new script and noticed that the bags around my eyes are decreasing. $500 for fillers and decreased self esteem due to looking older only to realize it was the damn eye drops! Hopefully my vision improves as well but after reading the reviews my expectations aren't very high. If you experience eye bags and decreased vision after using these drops it more than likely is caused by Xiidra!"

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Are you taking this medicine?

  • LRL
  • Taken for 1 to 2 years
  • December 18, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have been using Xiidra for over a year when my insurance insisted that I try this rather than Restasis ( go figure, it's actually more expensive). It does burn like crazy but I do feel like my eyes have been much better and I use significantly fewer OTC drops. My question is, has anyone else had issues with their pressures increasing? There may be no connection, but my pressures have increased significantly in this time and continue to climb despite several medication changes."

7 / 10
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  • Gramm...
  • October 5, 2016

Xiidra (lifitegrast) "First my Dr had me on Restasis, and after 2 months, it really did nothing for me! Now, the doc prescribed Xiidra! I've been using it for about 6 weeks, and it does seem to be working! I do have a huge problem, though! I'm assuming it is mostly older people using your drops? Why have the medication, in such a hard plastic container, that a senior citizen with Arthritic Hands, cannot open your packaging, or squeeze the eye drop dispenser, easily? Hopefully, someone at Shine, will take the time to read this, and answer me? Thank you!"

9 / 10
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More FAQ

  • Dont...
  • Taken for less than 1 month
  • December 28, 2020

Xiidra (lifitegrast) for Dry Eye Disease "Used Xiidra for three days and experienced all the awful side effects and made one eye feel gritty. Now hoping the pain in my cheeks will go away after discontinuing these acid-like drops. Good thing I got a free sample before shelling out the ridiculous amount of money they want for this."

1 / 10
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  • Jacob
  • December 11, 2020

Xiidra (lifitegrast) for Dry Eye Disease "It is a worthless product and appears to be a scam. There is not enough solution to get two good drops and the vials are nearly empty. It was a mistake to buy and pay a load of money for the useless product. Please don't buy it most likely will not help you"

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  • Julie
  • Taken for less than 1 month
  • June 13, 2019

Xiidra (lifitegrast) for Dry Eye Disease "Beware! I spent $300 on a month’s supply of Xiidra and I have had the worst side effects—burning eyes, metallic taste in my mouth, nasal drip tasting the medicine, and worst of all, nausea. I don’t understand how this drug was approved for use. I tried it every 12 hours for 8 days with no relief, only bad side effects. We should have a class action suit to at least get our money back for such a terrible drug!"

1 / 10
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  • Berly...
  • Taken for less than 1 month
  • August 18, 2019

Xiidra (lifitegrast) for Dry Eye Disease "After cataract surgery, my eyes would always look red and they stayed dry a lot. My eye doctor prescribed Xiidra, and it burned for a while then stopped. One night I put the drops in my eyes and my left eye burned so bad I couldn't stand. The next day the burning was still there along with my eye redder than every. I stopped the drops, and went back to using my over the counter lubricant . My eyes feel much better. I'll never use these drops again, they are NOT for everyone !"

1 / 10
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  • Nettie
  • Taken for 6 months to 1 year
  • February 18, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I too have experienced the bad taste and for that reason I only use it at night and drink water after administering it. My biggest problem, and I'm noticing it more lately are the bags under my eyes. Looking back at pics before I started this drug, I had absolutely no puffiness under my eyes. My left is worse than the right. I have been taking the drops faithfully since March of 2018. Has anyone else noticed this or is it just genetic and coincidentally just showing up in the last four to five months. I'd appreciate feedback if anyone else has experienced this. The eye drops have made a difference, my eyes are no longer red but clear and white now. I'd be interested to hear. Thanks"

5 / 10
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  • ARA
  • Taken for 6 months to 1 year
  • October 18, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I’ve been using Xiidra for almost a year now. My eyes were was so bad that it was hard to drive, work, etc because my eyes would be so dry and hurt so bad. The thing is, Xiidra works for my dry eye symptoms, but has caused awful sinus/throat issues. It’s so difficult to breathe, swallow, it constantly feels like there’s a huge ball of mucus in my throat. I’ve taken antibiotics and have scheduled an allergy test because I thought it was a sinus infection or allergies. Turns out it’s the eye drops, which sucks because they work. "

5 / 10
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  • Joy
  • Taken for less than 1 month
  • November 10, 2020

Xiidra (lifitegrast) for Dry Eye Disease "Application of product difficult ie leaning head down and pinching top of nose between the eyes for a long period of time... burning and pain continued for at least 20 minutes and blurriness remained for hours after application, and bad taste in back of mouth and throat for long period of time. I continued using as prescribed thinking side effects would disappear but nothing changed or improved after 20 days of use . I discontinued use and contacted my eye doctor."

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  • SLC
  • Taken for 6 months to 1 year
  • June 27, 2019

Xiidra (lifitegrast) for Dry Eye Disease "At first it cleared up my eye floaters. Expensive but really worked. Second month the burning was incredible but minor floaters. Vision was blurry for about 20 minutes minutes. As the months went on the burning continued, vision was blurry longer & seemed to have a lot more liquid ? My Dr basically shrugged it off. Then the sinus infections started. Worst I've ever had in my life. Now I am having bronchial / respiratory distress. Comes in waves, not able to always draw a breath when coughing. I can cough something up its that same bitter, nasty taste we have all learned to live with on this vile medication. Calling the Dr tomorrow as this is day 3 of these symptoms and I'm convinced it's the Xiidra. I'd rather have dry eye."

2 / 10
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  • MamaDoc
  • Taken for less than 1 month
  • July 2, 2023

Xiidra (lifitegrast) for Dry Eye Disease "I've had dry eyes for going on 50 years. I'm literally never without artificial tears nearby. I've tried everything. I'm no weenie, but I could not tolerate the stinging and burning with Xiidra. I gave it about three weeks but then stopped it. I consider the best treatment (ever) for me has been scleral lenses that keep my corneas happy. No cornea likes to be dried out, and the moisture provided by scleral lenses is priceless."

1 / 10
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  • Rachd...
  • Taken for 1 to 6 months
  • December 12, 2019

Xiidra (lifitegrast) for Dry Eye Disease "Xiidra did burn every time I'd dispense a drop. It would go away pretty quickly. I did experience the awful taste. It definitely worked for my dry eyes, however, the mucus build-up was a deal breaker for me. I had terrible drainage and a plug of mucus that would never go away. I could barely swallow at times without gagging. Cold and sinus meds didn't help. I figured out it was the drops and stopped them. Sinus troubles started getting better within 3 days. It's a real shame that this happened. My eyes were definitely feeling better, but I couldn't live with the side effects."

3 / 10
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  • ABano
  • December 31, 2020

Xiidra (lifitegrast) for Dry Eye Disease "I have tried Restasis, over the counter Refresh tears and gel drops and plugs. None of these have really helped. Then I went to another eye doctor who recommended I try Xiidra. I am SO glad I did! This eye drop helps with eye inflammation too (look it up!) and I have long felt this was part of my issue. I have Lupus with secondary Sjögren’s syndrome. I must look at a computer for work all day. These drops have made all the difference. In the beginning they made my eyes burn upon instillation, some dizziness, and the metallic taste...even some sinus symptoms but all of that subsided after a few weeks. I am so glad I stuck with it and gave these eye drops a chance!!"

10 / 10
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  • Mel
  • Taken for less than 1 month
  • June 18, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have been using Xiidra for less than a month for dry eye and within the first couple of weeks I rushed to see my doctor with an emergency of detached gel in my right eye and a hematoma behind my right eye. I had thousands of grey spots and a dark black floater blurring my vision. My doctor told me that the reaction wasn’t from Xiidra and refilled my prescription. I continued to use it and recently I have had large grey spots blurring my vision and darker spots floating across my vision. I believe the condition definitely is from Xiidra because I didn’t have this condition prior to taking it. My dry eye condition hasn’t improved. I stopped taking it."

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  • Kdano
  • September 1, 2019

Xiidra (lifitegrast) for Dry Eye Disease "Definitely helped with the dry eye. I used it for half a year. But...I’ve also been experiencing sinus issues and clogged/popping/ringing ears for six months. I’ve been in three rounds of steroids and seen many doctors about the sinus issues. It would never go away. I ran out of Xiidra two weeks ago. Now the issues are going away. Surprise surprise. I’m still going to the ENT next week, but I think I figured out my six month sinus and ear issues."

8 / 10
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  • Shanti
  • Taken for less than 1 month
  • December 16, 2020

Xiidra (lifitegrast) for Dry Eye Disease "I started taking Xiidra and I loved it but then I started noticing dizziness and a lot of pain in my cheeks and lots and lots of nasal discharge very soon I realized that I had gotten a really bad sinus infection and still suffering with it. Xiidra definitely worked for dry eyes but there is no way I could take it as it caused a severe sinus infection I have been having for a several weeks"

3 / 10
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  • Bubs
  • Taken for 1 to 6 months
  • March 17, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have been using this for 1.5 months. I recently used two vials in 1 eye because I felt extra dry and it has been 3 full days now of constant eye watering in 1 eye. It has gotten so bad that the skin under and around my eye has become red and tender, so painful. I can’t get my eye to stop watering and I am miserable. Has this happened to anyone else?"

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  • JKano
  • Taken for 1 to 2 years
  • August 5, 2019

Xiidra (lifitegrast) for Dry Eye Disease "Since I started using Xiidra, I have had extreme balance issues. This is not vertigo or dizziness. Started using Xiidra approximately July, 2018. August 2018 I experienced horrible one time vertigo. After that I had had balance issues. Wondering if there is correlation to Xiidra. Had used Restasis prior to Xiidra with no balance issues."

9 / 10
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  • VKP
  • Taken for 6 months to 1 year
  • August 23, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have suffered from severe dry eye for a long time. Initially I had been prescribed restasis, but turns out, I’m of a few that happens to be allergic to it. I’ve gone through an arsenal of dry eye treatments to include Lipiflow. Nothing worked. 6 months ago, I looked into IOL surgery with the hopes of forgoing contacts and lessening my dry eye symptoms, but my doctor wanted to improve my tear film and production before even considering it and was prescribed Xiidra. It’s very expensive without the help of insurance even with the discount card from the manufacturer, and it stings even after religious use for the past 6 months. But after 10 minutes, I use a preservative free artificial tear to remedy that. After about 2 months, my eyes started to feel better. They weren't as dry, and I was using artificial tears less frequently. I also no longer wanted to pluck my eyeballs out of my head, which was a good sign. My vision has improved so much so that I had to change my prescription."

9 / 10
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  • Munkey
  • Taken for less than 1 month
  • July 21, 2019

Xiidra (lifitegrast) for Dry Eye Disease "I have only been using Xiidra for two weeks. Initially, I was concerned by the burning sensation and began reading reviews. It frightened me so much, I almost discontinued use. The burning sensation abated within a day or two, and I can’t believe the improvement! I tried Restasis when it first came out, but there didn’t seem to be a noticeable difference. I have gone through more OTC eyedrops, warm compresses and everything else that has been suggested. Couldn’t make it through a night without feeling as though there were shards of glass in my eyes. I use an eye ointment at night and wear an eye mask, but until Xiidra, I have had no relief. Yes, it’s expensive, and I am fortunate that my health plan covers most of the cost. But, I would pay full price anyway. You only get one set of eyes. I am so thankful that this product came along!"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.