Leuprolide for Uterine Fibroids User Reviews (Page 3)

• Flood...
• Taken for 1 to 6 months
• January 9, 2013

Lupron Depot-Gyn (leuprolide) "I was having very heavy periods due to fibroids. My Gyn gave me the shot and it was amazing! No more periods! the trade off I took was night sweats and early onset menopause, but after such heavy bleeding that I have very low blood count, anemia and vitamin D deffieciency, it was well worth it! I'm only in the last few weeks of my first shot, but I can't wait for the next one!"

• Love...
• Taken for 1 to 6 months
• March 10, 2017

Lupron Depot (leuprolide) "I was on lupron a few years ago. For chronic pain multiple cysts I was bed ridden a week or two of of every month. This injection saved my life back then. I lost coverage so i stopped. Now I have coverage and decided to try it again... its not working this time!. I'm in pain all the time still. I have trouble sleeping at night or staying asleep my libido is gone..and I'm in the 4th month of treatment and started bleeding and have really bad pains again.. and my got flashes are back. The first month is the worst! Worst period of my life.. but there was no bleeding until now.. so I would recommend trying the once a month doses first"

• niki
• April 9, 2010

Lupron Depot-Gyn (leuprolide) "I didn't experience any major problems, except some mild stomach cramping initially and continued heavy bleeding for the first two injections. By my 3rd shot, just mild spotting and occasional cramping. I jut finished my 4th round, still no hot flashes, etc. I'm actually looking forward for my upcoming surgery soon."

• Anne
• Taken for 1 to 6 months
• November 19, 2021

Lupron Depot (leuprolide) "Lupron did not work for me. I took this medication as a last resort prior to having surgery to try and stop further growth of my already large fibroids and stop the hemorrhage level bleeding that I was regularly experiencing. This was a injection taken once every 3 months. While taking, my bleeding continued to get heavier. I had all the side effects and none of the stated good effects. The doctors don’t tell you that this medication may not work and when I told my doctor that it’s not effective and I continued to have heavy bleeding she still wanted me to continue taking this very expensive medication. For me it wasn’t worth it. The mood swings alone made me feel awful, I had memory fog, and the hot flashes were so intense. Take with extreme caution."

• Chocl...
• Taken for 1 to 6 months
• March 8, 2018

Lupron Depot (leuprolide) "I have had like 8 fibroids super big started 2015 March started bleeding blood clots. I was close to 50 years old so I found a study and she recommended lupron, I'm not gonna lie had 3 shots, my hair fell out - its gone, but for the pain I'm in right now might have to get my 4th shot. This situation changes your life style 100%. Horrible uterus pain is unbelievable. My hot flash/ cold flash worst are without lupron."

• chiom...
• May 15, 2021

Lupron Depot (leuprolide) "I took luprodex 3.75mg injection for 5 months on monthly basis to reduce the severe cramp.and pain associated with monthly flow. First month of injection was still painful but the subsequent months were normal and I also ovulated well on month 4. Then after the last dose, it took just 6 weeks before my period returned. It was quite normal but with a very light right abdominal cramp. I will do scan to check if the bulky uterus has reduced because I want to conceive too. One important observation is that it did not stop my period for those months . I usually see my period each month but did not see the next month when I stopped the injection. It was a beautiful experience though I had severe leg cramp/ arthritis..."

• Flori...
• Taken for 1 to 2 years
• August 9, 2021

Lupron Depot (leuprolide) "The Lupron injection was a lifesaver. In November 2019, I was 50 years old and I had been bleeding for 75 days, due to uterine fibroids. My hemoglobin was down to 5.1 and I had to have blood transfusions in the hospital. So far so good, no bleeding at all, until today, when I started bleeding again the first time, since November 2019. I'm now almost 53 years old and I'm scared to death, I have to go to the doctor on Thursday. Has anyone else had their periods restart after so much time, not having them following the Lupron injection? I know the injections wear off I'm not sure if they will administer more to stop the bleeding now ?"

• Mon
• Taken for 6 months to 1 year
• March 30, 2023

Lupron Depot (leuprolide) "I’ve had Lupron Depot for six months with no reduction in the size of my fibroids. It wasn’t hell with Lupron Depot, but my sex life was non-existent, the heat flashes were constant and it didn’t help the various pains I was experiencing from my large uterine fibroid (>10 cms). I also noticed that my knees got weak, and I constantly had back pain. I’m 29 years old, so this is alarming."

• Anonymous
• August 28, 2015

Lupron Depot-Gyn (leuprolide) "I started taking Lupron in November, 2014, and I am currently still taking the shots. I have had almost no side effects except for occasional hot flashes. I was put on Lupron because of heavy bleeding, due to my large fibroids. I am extremely happy with the results. My fibroids have shrunk to the point that I can now have a laparoscopic hysterectomy, rather than the old fashion full abdominal surgery. I haven't had a menstrual cycle in 9 months."

• KDIDIT
• Taken for 1 to 6 months
• January 18, 2023

Lupron Depot (leuprolide) "Took Lupron injections for several months, prior to surgery to reduce my fibroids. It did the trick, and the surgery was successful. Within two years, I got pregnant and had my daughter. Without Lupron, and my procedure it may have never happened. Had no issues with Lupron, except for the hot flashes I was forewarned about."

• Natasha
• Taken for 1 to 6 months
• July 7, 2022

Lupron Depot (leuprolide) "I have had many years of heavy, painful periods. Diagnosed with bulky uterus (size 16 weeks) with endometriosis and fibroids. My gynecologist recommended lupron depot to shrink my uterus before going for laprascopic hysterectomy. I'm 53 years old. I have had 2 shots now, and going for my 3rd next week. I have had a lot of side effects from this medication: night sweats (not every night, mild), insomnia, no energy, restless legs/muscle spasms, depression (cry every day at least once) and mood swings (my poor family) So next week when I get shot #3 I am hoping that he will have my surgical date booked as I cannot live with the pain and constant bleeding. The shot plus add-back therapy has only given me hope that I will eventually get back to normal and better quality of life."

• Ihate...
• Taken for 1 to 6 months
• May 19, 2017

Lupron Depot-Gyn (leuprolide) "I was on this medicine about a year ago but I only took it twice over 6 months(it was an every 3 months shot) I did not see any difference in the size of my waist. I didn't have professional test to show me a change in my size, I measured my waist each day. The measurement didn't change at all. Multiple doctors advised m that there would be no change if any due to the fact that I was very large. I recently had the Acessa procedure to help shrink the fibroids small enough to manage with a myomectomy surgery or hopefully without any other surgeries. At this point, it has been six weeks since the surgery and I am too afraid to measure myself yet. Will update in a couple months or so."

• Chelle
• June 27, 2018

"I have been taking the Lupron shot for fibroids. I was bleeding so heavy I was wearing diapers could not wear pads anymore when I suffered my 6th stroke I told my doc look you are not putting me on any blood thinner suntil you fix the problem down there. The first shot I bled afterward for like 3 days. But not as heavy as I normally would. My next shot is in July 2018. The first time I took the shot I had mood swings hot flashes at night headache and sleeplessness. It takes you on a journey but my fibroids are shrinking tremendously. The newest side effect I discovered is swollen gums. No fun. Do what you can to preserve your smile while taking this drug or you can lose your teeth. I used to have a beautiful smile now that is gone. The only drawback I have."

• Anna
• Taken for 1 to 6 months
• October 12, 2022

Lupron Depot (leuprolide) "*Update from post Sept 23* It's been over 1 month since my Lupron shot and I have been bleeding continuously since Sept 21st. On and off from light spotting to filling pads every 30 minutes with large clots. I can tell the shot has effected my hormones as I get hot flashes through the night to the point of sweating, I loose my train of thought and I forget easy. My Gyno just told me to increase iron intake from 150 to 300 and take TXA when needed. I completed 3 iron IV'S to help build my blood. Hopefully I will stop bleeding for my surgery on Nov 14th."

• Anonymous
• September 2, 2021

Lupron Depot (leuprolide) "I have not had the injection yet but am taking the one month version today. I am nervous after reading these things. I have over 20 fibroids. One that is 10 cm, I can feel touching my rib cage.... YES, my rib cage. This will be my second fibroid surgery but this one is worse. Has anyone had a provider say to use progestin (low dose) to help minimize the side effects? I was told you should not use estrogen based BC with these products. Will I need calcium/vit D for my bone health? I am worried about hair loss. The Anemia I have has already made my hair fall out. I don't need any more help with that. Please share your experiences."

• Neutral...
• Taken for 1 to 6 months
• July 16, 2023

Lupron Depot (leuprolide) "I was put on a Lupron Depot shot monthly, with add back hormones because of my age (29), after trying number of unsuccessful treatments for heavy bleeding from fibroids (multiple, 10 cm largest). The first period on Lupron was heavier than normal but I did not have one again until 3 months after my last shot. I only took it for 6 months because the side effects were horrible, but on the bright side I didn't have a period for 9 months. The side effects I experienced were: extremely dry skin to the point of peeling off my face in chunks, zero sex drive, significant weight loss, and depression. I was put on a higher dose of add back hormones to try to address the side effects, but ultimately stopped filling my prescription as I wanted to feel like myself again. To date, it is the only intervention that has controlled bleeding from my fibroids other than the Kyleena IUD. Fibroids have grown back since stoping Lupron."

• Anna
• Taken for less than 1 month
• September 23, 2022

Lupron Depot (leuprolide) "Back in Sept 2019 I had a submucosal fibroid at 1.3cm in size. I was offered Lupron back then but didn't pursue it. Covid hit and I didn't end up doing anything other than iron supplements. Dec 2022 I decided to see a naturopath as my symptoms were getting worse (heavy periods, clots, extreme tiredness, pale skin, painful intercourse) July 2022 I had the worst period ever which put me in the hospital needing 2 blood transfusions. I had an ultrasound which confirmed my 1.3cm fibroid had grown to 8.3cm. Due to my condition we agreed to have a partial hysterectomy. Surgery is Nov 14th. I took Lupron 11.25mg shot on Sept 6th. I will have 3 iron IV's prior to my surgery to build hemo (Sept 20, 26, Oct 4) before surgery. Sept 22nd I started bleeding like a normal period but day 3 now is heavy with clots. I am on tranexamic (2/8 hrs) but will change to 2/6hrs as the bleeding isn't slowing down. No other major symptoms yet other then 2-3 migraines. Will re-post with updates."

• Anonymous
• November 17, 2009

Lupron Depot (leuprolide) "Hot flashes throughout the day; moodiness and moderate depression and moderate fatigue."

• Sulia...
• November 20, 2015

Lupron Depot (leuprolide) "This medicine has given me horrible headaches. Lost a lot of hair gained weight insomnia."

• Anonymous
• Taken for 1 to 6 months
• July 1, 2016

Lupron Depot (leuprolide) "Lupron did not work on me. I still had heavy periods and serve cramps. My fibroids grew and did shrink. I was very angry that the shot didn't work"

• Mclar
• April 25, 2017

Lupron Depot (leuprolide) "It cause me permanent hair loss."

• Tammy
• Taken for 1 to 2 years
• December 15, 2016

Lupron Depot (leuprolide) "Finally, something that worked for my fibroids! Yay"