Leuprolide for Prostate Cancer User Reviews (Page 4)

• Ganna
• Taken for 1 to 2 years
• January 1, 2020

"I will share my husband’s experience with Lupron D. He is not here to share. He was 67 years old. Diagnosed with stage 3 prostate cancer four years ago. He was treated with radiation and Lupron D. Both made his life so miserable he ended it. He was not depressed before. When he complained to the oncologist, the doctor blew it off. I am a grieving widow. I miss my husband."

• Dave
• August 19, 2021

Lupron Depot (leuprolide) "Have had lymphoma for many years from Agent Orange exposure in Vietnam. Had exam and PSA test annually until I was 75 and doc says you have prostate the size of 15 year old and PSA is normal, so you don’t need to come back. Now 80 and PC metastasized to lymph nodes in neck. PC is also related to Agent Orange. Started with 30-days of Casodex and 90-days of Lupron. PSA went from 75.5 to 0.06. Lupron side effects not too bad, but seem to be getting worse as I approach next injection in a couple of days. I’m hoping to switch to a mCSPC (castration sensitive) medicine, instead of the Lupron, which is mCRPC (castration resistant)."

• 2-putt...
• Taken for 5 to 10 years
• February 16, 2016

Lupron Depot-Gyn (leuprolide) "I have advanced prostrate cancer and have found that when I stop or delay a 90-day injection, my PSA climbs. From June 2010 (PSA over 350) through Jan 2013 (PSA 9) my cancer was controlled. I suspended the shots for 18 months due to cost and my PSA climbed to 270. In 5 months, my PSA is at 4.2."

• boywo...
• Taken for 6 months to 1 year
• October 20, 2017

"Diagnosed October 2016 stage 4 metastatic prostate cancer 2-8s 1-9 gleason....perineal invasion.....ductal variant hystoligy. It is rare, very aggressive with bone mets pelvis , rib and possible knee just waiting results from MRI. I'm having 3rd shot (22.5mg) of this nasty stuff. I work in construction so muscles important and this gives a noticeable reduction, with hot sweats - when its 98 percent humidity I pour sweat and have muscle aches. My memory is stuffed up .....and everyone is right drs just don't even want to hear about your side effects. And sex for get about it. But my PSA is .07. I want to take a break but doc says with my aggressive type ....no way. I'm just buying time, we all have a expiration date.........enjoy life........boywonder"

• kluff
• July 19, 2017

Lupron Depot-Gyn (leuprolide) "My experience on this drug mirrors that of albert owens. The side effects are truly awful, no energy, no sex, headaches, no sleep I am either sweating or peeing all night. Deep depression, anxiety, nausea, memory loss,l egs swelled, 2 stone weight gain around middle, no quality of life left. I must agree with burned out wife also because my wife feels just like her and it is not nice. I have over another year on this stuff, I am happy for the men it has worked for bless them, but for myself and others it can be a nightmare. Take care and good luck to all."

• Peter
• Taken for 6 months to 1 year
• February 27, 2022

Eligard (leuprolide) "I am a 77 year old 188 cm (6ft 2) slim broad shouldered ( thanks to the boxing I did ) diagnosed with a PSA of 20 Gleeson score 9, Resting pulse rate of 45.The pressure I had to have the prostate out was immense but I refused ( I had a urologist loose his temper with me over the phone because I would not have it out) .9 weeks of intensive radiation treatment and guess what PSA is now zero BUT the injection of Eligard bumped my pulse rate from 44 to 80. With zero testosterone I went to strip club with friends - nothing happened. An hour of watching porn - no reaction. I'm slated for another injection But another 6 months of life as a monk is really scaring me. If I don't do it soon I will forget how to do it! Peter Nowlan Australia"

• Mr Wiz
• January 23, 2016

"I had prostate cancer that had metastasized and was given the 3 month leuprolide shot along with casode; within 24-48 hours had horrible side affects, memory loss, couldn't walk or even stand up, dizziness, weakness. 3 days later I was taken to ER and had blood clots in my lung. I do not recommend the leuprolide and casadex combination. Not sure which one is worse but would give it a -1 rating if available."

• Woody...
• March 29, 2023

Lupron Depot (leuprolide) "Been on Lupron now for 3 1/2 years. I’m 84 years old with metastatic prostate cancer. Lupron did take my psa from 196 to almost zero. However, I have all the side effects…fatigue, hot flashes, ED, and a 13 pound weight gain around the middle. I’m alive but have a very little quality of life. There are new studies showing that very high doses of testosterone (I know it sounds crazy) have shown to reverse the cancer and given men a much better quality of life. I’m going for a new treatment soon as the Lupron is starting to fail as my psa is creeping up. my advice is if you can avoid Lupron do it at all costs. Your life will change with the first shot."

• Bayst...
• August 27, 2017

"Had a radical prostatectomy in 2009. Discovered to have spread to spine in 2017 and was told I would be on Lupron till "the end". For me the most telling effect apart from weight gain and hair loss (chest) has been the incredible emotional roller coaster I have been on! What is especially striking is the fact that memories from 25 years ago and the split from my first wife seem more "real" to me now than my current state! The pain of those old memories and regrets is exceedingly intense! Very strange!!! In fact those old emotions became so powerful I sought out a psychiatrist to help me cope. Lorazepam has proven to be a godsend!"

• fatigue
• Taken for 1 to 6 months
• June 1, 2023

Lupron Depot (leuprolide) "Tried Lupron Depot every 3 months two times, but severe fatigue, occasional dizziness and passed out. Side effects were not acceptable to me. Orgovyx + Xtandi is much better. Although, without testosterone: fatigue, no erection, lack of enthusiasm, and weight gain."

• Scott
• Taken for 6 months to 1 year
• May 17, 2023

Lupron Depot (leuprolide) "Diagnosed with prostate cancer with a Gleason 7, PSA 8.2 Received a 6-month Lupron shot Nov 15, 2022, and 20 secessions of radiation starting Jan. 18, 2023. I have suffered hot flashes several times a day and night and they have become more intense in the last 6 weeks, by that I mean I get completely soaked several times a day and night. I have gained around 20 Pounds, have a loss of muscle strength, neuropathy in my hands, bone pains in my feet, back pain, mood swings, and lack of motivation to get moving. I do ride my bicycle several times a week, about 100-plus miles and this is how I keep my sanity. Last appointment with the doctor was on May 15th."

• Rich
• October 27, 2020

"I was diagnosed with Advanced Prostate cancer- non metastatic- in July, 2019, with Gleason score of 9,8, and 7. Began Elegard/Lipron in August,2019, 2 months prior to 45 days of Radiation and have continued on a 4 month regimen of Lupron injections. During the first year on this drug I had the basic side effects of hot flashes, chills, mood swings and some aches. Now going on the 2nd year on Lupron, I now have severe side effects with a lump on my left knee with severe swelling with over use; pain in my hips and shoulders that come and go: tingling and numbness in my hands that wake me up at night; ringing in my ears; fatigue; and I have lost the ability to use my right thumb that come and goes like severe arthritis. I was previously a very calm and caring person but now become angry and have high risk behaviors not caring if I get into an argument with someone which I try to control. I use to be avid runner but cannot do this anymore due to severe pain and swelling in left leg."

• Mark
• Taken for 1 to 6 months
• November 22, 2023

Lupron Depot (leuprolide) "65-year-old who had a Prostectomy in Dec 2022. Psa was still elevated after surgery. PET scan revealed PC in pelvic lymph nodes. Prescribed salvage radiation and ADT. On med for 5 months now (2 three-month 22.5 injections). PSA was undetectable at the time of the 2nd injection. So I guess it works, or was it the 37 radiation treatments I received in Jun/July. Won't know unless I discontinue Lupron. As for side effects, they have been somewhat minimal. Libido gone. Loss of pubic hair but returning, a decrease in the size of the penis but returning, weight gain of 5-8 pounds. Hot flashes, but they have decreased significantly (I take Vitamin E). I have joint pain, especially in hands, but I am hoping Vitamin D will help. Sleep is getting much better. My mood has been very good. I exercise frequently, eat healthy, and have no stress. I think that helps a lot. I think I will continue with injections. The doc wants to do 2 years of injections. Overall, not too bad."

• Chuck
• Taken for 6 months to 1 year
• May 19, 2023

Lupron Depot (leuprolide) "76YO. Got Bicaludimide pills and a Lupron shots twice before my "High Image Focused Ultrasound (HIFU)" operation to kill my prostate in 2019. Fatigue was my worst side affect. Did serious and intense Max Gerson Cancer Protocol therapy for three years. Totally off alcohol and mostly vegetarian. Mostly no carbs. Lost twenty pounds. When PSA started creeping up my urologist put me on strictly Bicaludimide pills once a day (50mg). Negligible PSA for almost two years until tender breast and some enlargement took me off it. Been off for six months and back to normal in every way including testosterone. PSA is creeping up again and I think I will go back to the pills but only once or twice a week and see how my PSA does. I get the psa checked every other month. I feel very good."

• 1968gto
• Taken for 2 to 5 years
• February 26, 2013

Lupron (leuprolide) "I have been on Lupron for two years. I got my last shot in December. It has kept my PSA under 0.03. Can't wait to see if it is still that low after 3 months! You learn to live with the side effects."

• DonAl...
• March 30, 2009

Lupron (leuprolide) "While I do believe it has lengthened my life, the side effects are difficult to deal with. I am extremely sun-sensitive, also have a rash on my wrists that doesn't go away."

• Anonymous
• Taken for 1 to 6 months
• April 17, 2020

Eligard (leuprolide) "Eligard caused Hot flashes only. If I had read these comments before, I would never had Eligard! Horrible!"

• Tom...
• June 16, 2016

Lupron (leuprolide) "Been on this drug 15 months No libido at all day sweats night sweats and hot flashes irritability and erratic memory episodes PSA from 30 to .01 after radiation and continues today"

• Mark
• Taken for 6 months to 1 year
• December 12, 2019

Eligard (leuprolide) "Hot flashes, bone pain, breast enlargements, tired, don’t about anything anymore. Looking for a way to reverse it!"

• Lupron...
• July 21, 2019

Lupron Depot (leuprolide) "Brain fog, hot flashes, bone chills and memory loss. Drug is poison."

• Anonymous
• May 25, 2016

Lupron Depot (leuprolide) "My dad had 1 shot of Lupron at age of 80 for elevated prostate cancer. He lost control of his muscles, was unable to walk and accelerated his dementia. My dad passed away 10 months after the shot."

• Flor...
• July 22, 2014

Lupron Depot (leuprolide) "Hot flashes and chills. Stomach became larger and weight gain. Hot flashes are very annoying. Fainted and doctor said it probably was due to dehydration."

• Slugger
• May 10, 2015

Eligard (leuprolide) "It works for me - long story short I'm going for my second shot on the 21st of this month"

• Think...
• Taken for 1 to 2 years
• December 14, 2022

Eligard (leuprolide) "If I had to do it all over again I would not take Eligard. I question why this poison was ever approved"

• Mully...
• September 24, 2017

"Weight gain. HOT Flashes. Shrinking testicles"