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Itraconazole for Onychomycosis, Toenail User Reviews

Brand names: Sporanox, Tolsura

Rating: 5.7

Itraconazole has an average rating of 5.7 out of 10 from a total of 12 reviews for the treatment of onychomycosis, toenail. 50% of reviewers reported a positive experience, while 42% reported a negative experience.

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Reviews for Itraconazole

  • Anonymous
  • August 9, 2009

Itraconazole "After a year on Sporanox, my badly infected and painful toenail grew out. Odd part is having the infected toenail and other minor medical conditions for 30 years, Sporanox cleared up many other conditions. The doctors said not possible, however, I know there is a connection. Heart arrhythmia, gone, non-healing nose/anal fissures, gone, facial/scalp/pubic psoriasis plus mucous membrane inflammation gone for treatment duration, but back after a year. A year later, the original nails were still clear, but a different nail infected with peeling, scaly skin across 1/3 of my foot. Strangely, it didn't get worse. Back on Sporanox. Seems to be clearing both conditions. The returning problems above also vanished when restarting Sporanox."

8 / 10
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95 Report
  • Bog...
  • June 27, 2009

Itraconazole "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

5 / 10
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46 Report
  • Anonymous
  • Taken for less than 1 month
  • November 19, 2019

"I was prescribed this medication, and I reacted badly to it. I took one dosage, and shortly after, my legs began to feel numb and tingly, and I was having trouble breathing. It was too strong of a medication for me."

1 / 10
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20 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • May 23, 2022

"Two tablets (100 mg each) of itraconazole twice daily for seven days. Then three weeks off medication, followed by a further seven days, followed by another three weeks off, and then a final seven days on itraconazole successfully treated my toenail fungal infection. My toenail has returned to normal. Absolutely no negative side effects reported and felt good taking this medication. 10/10."

9 / 10
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10 Report
  • Anonymous
  • Taken for less than 1 month
  • July 23, 2020

Itraconazole "I was prescribed Sporanox to take as a pulse therapy for a toenail fungal infection. Day 1 was okay. Woke up at night, thirsty and with a feeling of sand in my mouth. Day 2, small cough and breathing not 100%. Day 3, the worst nightmare of my life. Let me just say, I'm a healthy young person, running around 80 miles a month in addition to regular gym sessions. My resting HR is 45. Never in my life have I had even a headache. That day, I was extremely tired, coughing, the strongest headache in my life, constantly thirsty, literally thought the next stage was dying. It's day 5 (I stopped on day 3), and I still feel a headache and the lymph nodes behind my ears hurt very much for the second day in a row. I can't move my head too much without hurting. If you're thinking of taking this for a fungal infection in toes or fingers, consider a different therapy like laser options. It was too short of a therapy to see any effects, so I can't say if it would be effective, the side effects were too much."

1 / 10
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22 Report

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  • Ann...
  • September 19, 2009

"I took one course of itraconazole (pulse therapy, 400 mg/day during 1 week), after being unsuccessfully treated for onychomycosis of my 5th foot nail (I had it for years). So, since terbinafine didn't help, I decided to use this one, as my doctor advised. Now I have my new nail growing healthy, so my decision is to continue the treatment with this drug."

10 / 10
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36 Report
  • Mik...
  • April 28, 2017

Itraconazole "Took Sporanox for approximately seven months to cure complete infestation of toenail fungus (both feet/all toes). Sporanox had started to clear it all up when I ran out of the capsules. I was overseas and unable to get a refill. After stopping the medication for a period of time, the fungus returned to its previous state. Upon my return to the U.S., I did not pursue another Rx due to concerns over liver damage. But if your liver is healthy and you can take it for an extended period of time, Sporanox seems to be a very effective cure. Much faster than topical meds I've used since then, although, like I said, soon after I stopped taking Sporanox, the fungal infection returned to its previous state."

10 / 10
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21 Report
  • Kol...
  • Taken for 1 to 6 months
  • April 26, 2021

Itraconazole "Tried Diflucan and terbinafine, which ended up with me vomiting and diarrhea and no success. Sporanox is a lifesaver. No side effects at all, feels like I'm eating candy. I'm at 2 months of treatment, and I have to keep going because I had some relapse, but right now it seems it's going away once and for all! Let us hope!"

10 / 10
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8 Report
  • gpu...
  • Taken for less than 1 month
  • April 6, 2023

"My mother (73) took this medicine for toenail fungus, and within a couple of weeks, her ankles had swollen up, and there was a large red rash on the legs. I think it should NOT be used on seniors. Two weeks later, after suspending the medicine, she cannot put her shoes on, and the rash persists. We are concerned there have been irreversible effects. AVOID this medicine."

1 / 10
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3 Report
  • Ace...
  • Taken for less than 1 month
  • April 18, 2021

"I was put on this for toenail fungus. After taking it for two weeks, 200 mg a day, I had to stop. The side effects are bad: no interest in anything, feeling sad, crying. Tried, so I don't know if it works or not. Had to stop, the side effects are so bad."

3 / 10
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4 Report
  • Anonymous
  • April 23, 2009

"This is perhaps one of the best medications out there. It will kill the fungus as long as you stay on top for about 6 months to a year with the medicine. Too bad it's not over the counter yet."

9 / 10
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13 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 3, 2023

"I have been taking this medication for months, and it has not done anything for my toenail fungus."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.