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Leqvio User Reviews & Ratings (Page 2)

Leqvio has an average rating of 7.6 out of 10 from a total of 48 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 4% reported a negative experience.

Reviews for Leqvio

  • Jayne
  • Taken for 1 to 6 months
  • April 13, 2024

For High Cholesterol, Familial Heterozygous "I've just had my second injection. Cholesterol dropped, so that's a positive. I still have an injection site rash, possibly due to this last injection being very uncomfortable, unlike the first one. My IBS has been really bad this time too, but not sure if connected. Jury's still out as to whether I would have a 3rd."

6 / 10
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4 Report
  • Harvey
  • Taken for 1 to 6 months
  • June 4, 2024

For High Cholesterol "Had starter dose end of October. Had regular injection Jan. 31. Began having leg spasms, some cramping. It's June and symptoms have not abated. How long should any side effect last? LDL-C went from 122 to 55 after the second dose."

10 / 10
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2 Report
  • South...
  • Taken for less than 1 month
  • June 4, 2024

For High Cholesterol, Familial Heterozygous "This is in regards to side effects of Leqvio. Had the first injection about five days ago. No pain or redness at the injection site. A bit of soreness at the injection site for about 24 hours. A lethargic feeling off and on since the injection. A small amount of muscle or joint pain in the first 72 hours after the injection. No diarrhea as yet. Slightly loose BMs. No fever. Have experienced periods of being 'light-headed', i.e. feeling faint. Have not communicated this to my physician yet. Will do so later this week. I am hopeful this injectable medication will lower my LDL and thus, my total cholesterol number."

9 / 10
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1 Report

Frequently asked questions

  • revric
  • Taken for 1 to 6 months
  • April 26, 2024

For High Cholesterol "The Leqvio injection was a brief stop at the cardiologist's office. Typical, brief shot in the back of the arm. Easy. They held me there for ~15 minutes to ensure no injection symptoms. The nurse administering the injection did it very well. No pain or discomfort. I don't have serum numbers yet so I am unable to speak to the effectiveness, but I wish all my meds could be this easy."

9 / 10
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1 Report
  • Stacy
  • Taken for 6 months to 1 year
  • March 14, 2024

For High Cholesterol, Familial Heterozygous "I could not take statins without side effects. Sore muscles aching joints. I was crying at night, could not sleep. After using Leqvio for 2 doses, I don't even need to take any statins. I also changed the way I eat."

10 / 10
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Are you taking this medicine?

  • Drsir...
  • Taken for 1 to 2 years
  • July 21, 2024

For High Cholesterol, Familial Heterozygous "I took statins for 38 years. While they may have lowered my cholesterol, they did not mitigate my eventual need for CABG surgery. I took the Repatha shots for 2 1/2 years and didn't have too many negative side effects, but didn't like the need for injections every 14 days and began noticing that I would get purpura. My cholesterol level remained at good levels. Changing to Leqvio was beneficial because there is only a need for 2 injections annually; however, my cholesterol readings are somewhat higher and the purpura has increased. I fear that I am beginning to gain a little weight from Leqvio since there have been no changes in my diet or exercise routines. I am very bothered by the frequency and size of the purpura."

8 / 10
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  • Linda
  • Taken for 1 to 6 months
  • July 9, 2024

For High Cholesterol, Familial Heterozygous "Started taking first shot March 2 shot June. It is, I believe, responsible for incredible muscle. Stephen is in pain especially in my back and my ribs. It did, however, lower my numbers quite a bit, so I’m grateful for that, but I am not sure it’s worth it if I’m going to be in such severe pain. I hope that the pain goes away in a few weeks when it works through my system."

7 / 10
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More FAQ

  • Divin...
  • Taken for 1 to 6 months
  • March 15, 2023

For High Cholesterol "I am having the most severe muscle pain and tight muscles I have ever had since I have been on Leqvio. Has anyone else had this?"

4 / 10
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88 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

For High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision and sweating"

1 / 10
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53 Report
  • Eliot...
  • Taken for 6 months to 1 year
  • April 3, 2024

For High Cholesterol "About a month after Leqvio shot, I get heartburn, nausea, belly cramps, fatigue. Numbers are good, but not liking the side effects. Anyone else having similar issues?"

7 / 10
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16 Report
  • Susan...
  • Taken for 1 to 6 months
  • May 25, 2023

For High Cholesterol, Familial Heterozygous "Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee related issues."

4 / 10
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40 Report
  • L ham
  • Taken for 6 months to 1 year
  • May 28, 2024

For High Cholesterol "It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

8 / 10
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5 Report
  • David
  • Taken for 1 to 6 months
  • August 6, 2023

For High Cholesterol "Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

10 / 10
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20 Report
  • Mlh
  • Taken for 1 to 6 months
  • March 12, 2023

For High Cholesterol, Familial Heterozygous "I had a terrible reaction to repatha so I requested Leqvio. I had my first dose 3 months ago and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."

10 / 10
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23 Report
  • Eliot...
  • Taken for 1 to 2 years
  • May 22, 2024

For High Cholesterol "Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

7 / 10
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4 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

For High Cholesterol "Took first dose in October 2022. Bad cholesterol was 105 Second does in January Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer"

10 / 10
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15 Report
  • roger...
  • Taken for 6 months to 1 year
  • May 19, 2024

For High Cholesterol "Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

6 / 10
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2 Report
  • Thomas...
  • Taken for 2 to 5 years
  • January 1, 2024

For High Cholesterol "Worked for me, been taking it for a couple of years."

10 / 10
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3 Report
  • jack
  • Taken for 1 to 6 months
  • February 29, 2024

For High Cholesterol "Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
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  • shellie
  • Taken for 1 to 6 months
  • April 12, 2024

For High Cholesterol, Familial Heterozygous "Have felt better, not had blood work yet to check levels."

10 / 10
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  • Fred
  • Taken for 2 to 5 years
  • June 29, 2024

For High Cholesterol, Familial Heterozygous "Have just received my 4th injection. Further to my May '23 post. Cholesterol has remained low, slight muscle pain continues, believe it has contributed to some hair loss. Feel overall more energetic."

9 / 10
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  • Mary
  • Taken for 6 months to 1 year
  • April 18, 2024

For High Cholesterol "Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
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  • Anonymous
  • April 15, 2024

For High Cholesterol "Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.