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Hydroxyzine for Pain User Reviews

Brand names: Vistaril

Rating: 6.9

Hydroxyzine has an average rating of 6.9 out of 10 from a total of 29 reviews for the treatment of pain. 59% of reviewers reported a positive experience, while 21% reported a negative experience.

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14%
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34%
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10%
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14%
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0%
5
3%
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3%
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3%
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3%
1
14%

Reviews for Hydroxyzine

  • Reb...
  • August 23, 2019

"Could not figure out why the only time my tooth (and thereby entire jaw) only stopped hurting at night... I take hydroxyzine and gabapentin together at night for anxiety. No more mystery! The two together should be ALL they prescribe for tooth pain! Why is no one screaming this from the rooftops for people with tooth pain? Best remedy ever, hands down."

7 / 10
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61 Report
  • Anonymous
  • August 14, 2012

Hydroxyzine "I have some conditions and I'm in pain 24/7. I use Fentanyl 100mcg every 72 hours and Percocet 2 every 6 hours. I have other medications; but with Vistaril, I don't have to use the dosages of Percocet as prescribed. I'm a veteran."

9 / 10
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108 Report
  • Seb...
  • January 17, 2015

"Hydroxyzine works great mixed with any opioid for anxiety, pretty good with withdrawal from benzodiazepines. Works like a charm. If you have this medicine, keep it around when needed, it could save your life."

9 / 10
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80 Report

Frequently asked questions

  • scb...
  • July 19, 2016

"Finally, a migraine preventative that works for me! I was having up to 10-15 migraines a month. None of the standard migraine preventatives worked well for me, or I had side effects that I could not tolerate. I have 2 levels of migraines -- those that Excedrin Migraine takes care of and the ones that need my triptan (Axert) medicine. Within a week of starting the hydroxyzine, my 'low-level' migraines all but disappeared and I was down to 3-4 'triptan' headaches a month; the month after that the 'triptan' headaches were gone. I haven't had a migraine-free stretch like that for over 15 years! The side effects have been minimal -- I was drowsy during the day for the first week, but that has gone away. On the plus side, I'm sleeping better too!"

9 / 10
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58 Report
  • TDi...
  • February 28, 2016

"I was prescribed hydroxyzine for severe itch. No doctors have a clue why I have these severe itching events. But I also have other problems. I have spinal stenosis and am using fentanyl 50 mcg/hr every 3 days. Still recovering from colon cancer surgery. Was just diagnosed with arthritis of my hip. There are days I cannot walk even with the fentanyl. Started taking hydroxyzine only when I itch, and it took a few days to put 2 and 2 together and realize my back and hip almost totally stopped hurting and I was able to walk without a cane or walker. The next time I took hydroxyzine for itch, same thing, I could walk without pain. I haven't told my doctor yet, wonder what he will say, and if this drug helps me, why didn't he give me hydroxyzine sooner?"

9 / 10
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59 Report

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  • Ski...
  • Taken for 1 to 6 months
  • February 15, 2020

"33/Female/Anxiety/Chronic migraine cycle for 2.5 years.... I tried every over-the-counter medication, anti-depressants, anti-seizures, and none of these medications rid me of migraines. I was prescribed this hydroxyzine for anxiety, and it broke my migraine cycle. This is even after several visits to the E.R. to receive various different migraine cocktails, combinations, and even ketamine couldn't get rid of my migraines. This med completely eliminated my migraines. I was able to find a neurologist who ordered 200 units of Botox per migraine protocol. After 5 rounds, I am finally migraine-free and not on hydroxyzine. I was taking 25 mg 3x a day and then 50 mg 3x a day. After 3 months, I became sedated, but after the 4-month mark, I became confused and couldn't find my car in the parking lot, walked out of the pharmacy almost forgetting to pick up this prescription, couldn't remember what exit to take off the interstate, etc."

10 / 10
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31 Report
  • Dan...
  • Taken for less than 1 month
  • September 6, 2023

"I have chronic cervical pain that puts severe pressure on the nerves. Physiotherapy is helping me, but muscle recovery is very hard with the lack of sleep. I am constantly on edge from the insomnia and pressure on the nerves. Hydroxyzine is the only thing that soothes and allows me to have deep recovery sleep. I take it before bed, and I am calm upon waking in the mornings (no existential dread). I'm only on half the 25mg dose. No side effects as of yet."

9 / 10
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12 Report

More FAQ

  • Aud...
  • Taken for 10 years or more
  • February 28, 2025

"My shoulder has been hurting for 5 months, and I notice since I have been taking my anxiety meds, hydroxyzine, my pain in my shoulder stops. I've been on it for over 10 years, but I take it every now and then when I get really nervous."

9 / 10
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2 Report
  • Hap...
  • Taken for 2 to 5 years
  • January 24, 2019

"25 mg of this drug is literally the only thing that helps my migraines. Takes about half an hour to work, and I still am aware of my headache, but it makes the pain much more tolerable and eliminates the accompanying nausea. I’ll take the profound sedation from this over migraine pain any day."

10 / 10
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35 Report
  • SPI...
  • July 28, 2015

Hydroxyzine "I take OxyContin 60 mg 3x a day, and Roxicodone 15 mg 4x a day for chronic back/neck pain. Sometimes I do too much walking or get severe neck pain that the pain meds don't control. I add one 25 mg Vistaril, and it enhances my pain meds' effectiveness. About 3 to 4 hours later, I become EXTREMELY drowsy and often fall asleep, not good in the middle of the afternoon! I think the occasional Ativan is almost as helpful, w/o all the sedation. Good drug, only if I can afford to be asleep."

8 / 10
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47 Report
  • Anonymous
  • December 2, 2009

Hydroxyzine "I was given Vistaril for pain soon after a neck fusion. The surgeon refused to believe that I was in such severe pain after he 'fixed' me. Within hours of taking the medication, I was in a deep fog. I could not concentrate or think clearly. This medicine also made my legs ache, and I could not sleep until this medication was out of my system."

1 / 10
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66 Report
  • Rox...
  • January 28, 2019

"I had four teeth pulled at the same time. Bad idea. The pain was horrendous. I took hydroxyzine/gabapentin together... this has been my only relief in five damn days of horridly, horrid, horrible mouth and jaw pain. Does NOT work on anxiety for me."

7 / 10
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25 Report
  • meg...
  • Taken for less than 1 month
  • December 20, 2016

"I have a very high tolerance for meds (all meds), always have, even as a child. Woke up in the middle of surgery at 7, after being given twice the adult dosage because I couldn't go to sleep. I noticed on opiates they help, but minimally. I noticed for a brief period when I had benzodiazepines for my anxiety, it aided my pain meds. But they took me off for another kind, and my opiates for pain and anxiety relief weren't being helped at all. They just switched me, and I notice the same aid to my medication the benzodiazepines provided, minus the fog. It doesn't help with my severe chronic pain on its own (I wish it were that easy), but I find that my meds work so much better in conjunction. My gabapentin seems to work better too. :) Finally, I can live a little better."

9 / 10
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28 Report
  • Cec...
  • Taken for 6 months to 1 year
  • March 19, 2022

"I usually suffer from a strange joint pain, which is not positive for R.A. When I take the hydroxyzine, it calms the pain down. I also suffer from sharp pains all over my body, and that also settles down a bit with the medication."

9 / 10
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9 Report
  • Noi...
  • Taken for 6 months to 1 year
  • November 24, 2016

"Hydroxyzine seems to help more with my reaction to pain than with the actual pain. If I take hydroxyzine while I have shin splints, I still feel quite a bit of pain; it's just that I feel significantly less distressed and distracted by the pain than I normally would be. It works best for pain if taken with an actual painkiller. I prefer using naproxen, as the hydroxyzine seems to counteract the stomachache I always get from this NSAID."

7 / 10
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23 Report
  • joe...
  • Taken for 1 to 6 months
  • April 29, 2022

"I had an ankle arthroscopy procedure that didn't go well. Six weeks after the procedure, I have sciatic pain from my butt to my toes. The pain wakes me up at night, and I have to get up and take NSAIDs and gabapentin to help relieve the pain. My mental health doctor put me on hydroxyzine for depression. It really does nothing for depression, but I noticed it does help for pain. It is crazy to me that an antihistamine works for pain, but it does."

7 / 10
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8 Report
  • Fed...
  • Taken for less than 1 month
  • March 7, 2016

"I've been on this med for 5 days now. MD put me on 50 mg along with my Oxycodone 15 mg 4x daily for severe pain in my medial scapular region. At 50 mg, all I do is sleep. I tried breaking them in half and taking 25 mg also. At 25 mg, I'm in a fog, feeling tired, sad, overall depressed basically. Overall effectiveness of this med for pain... I'd give it a zero!"

3 / 10
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25 Report
  • Not...
  • Taken for 6 months to 1 year
  • December 4, 2020

"I use hydroxyzine to treat a comorbidity of conditions. I feel high when I take it, though. It is best if I take it at night, but my doc says it's good to take it if I have symptoms a lot as an allergy med. I have weird thoughts on this drug, and I feel drunk and on a weird drug kind of feeling. Maybe it's the sedative effect. I mean, it works for what you take it for, but the negative is that you have to deal with weird thoughts all the time and loopy feelings. I'm not sure I can handle this anymore."

5 / 10
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12 Report
  • Anonymous
  • September 4, 2011

Hydroxyzine "Great pain medication, much better than oxycodone without the side effects."

9 / 10
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83 Report
  • Anonymous
  • November 16, 2011

Hydroxyzine "Good - in combination with gabapentin and hydrocodone for neuropathic pain."

8 / 10
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74 Report
  • Anonymous
  • March 14, 2010

Hydroxyzine "Awesome, works like magic!"

10 / 10
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66 Report
  • CPJ...
  • Taken for 2 to 5 years
  • March 18, 2021

"The drug works well for chronic pelvic pain. I take 50 mg at early night, sleep well, and wake with less pain."

9 / 10
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17 Report
  • jer...
  • November 11, 2009

Hydroxyzine "I have been taking this medication for several months for pain. It has provided minimal relief for arthritic pain."

4 / 10
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50 Report
  • lei...
  • September 24, 2009

Hydroxyzine "I have seen Vistaril prescribed a number of times for pain, especially muscle pain. I found it useless for pain itself, but it was great to potentiate opiates and stop rashes that might develop."

2 / 10
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53 Report
  • hds...
  • October 12, 2009

Hydroxyzine "This medication made me very nervous and depressed. Almost like the effects I had from oxycodone. I had to stop taking it after 4 days."

1 / 10
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38 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.