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Glycopyrronium topical for Hyperhidrosis User Reviews

Brand names: Qbrexza

Rating: 5.6

Glycopyrronium topical has an average rating of 5.6 out of 10 from a total of 50 reviews for the treatment of hyperhidrosis. 38% of reviewers reported a positive experience, while 34% reported a negative experience.

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26%
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10%
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2%
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8%
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8%
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12%
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6%
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10%
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18%

Reviews for Glycopyrronium topical

Commonly mentioned side effects
  • Boo...
  • Taken for less than 1 month
  • April 19, 2021

"Tried Qbrexza for underarm sweating. This product does what it’s supposed to - it stops sweating. However, the side effects are simply not worth it. I had severe dry mouth and nose within 4 hrs of using under my arms. I did not sweat anywhere else either - hands, face, groin, feet, for that matter. I could barely talk or swallow and drank/sipped water constantly. It’s now been 14 hours since initial application, and I’m up at 3:30 am unable to sleep due to this dry mouth. I had to skip dinner because I had zero saliva to help break down my food. My eyes are also looking red and dry, but I’m not ‘feeling’ any issue with them. This dry mouth is incredibly horrible though. Had I known it was going to be this severe, I’d have passed in a heartbeat. After all the water I have drunk in the past 14 hours - literally over 1.5 gallons, I am worried as peeing is getting increasingly difficult."

2 / 10
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36 Report
  • DDB...
  • November 3, 2020

"I'm an ER doc, taking Adderall since high school. I tried older meds first for my hyperhidrosis, Robinul and Oxybutynin, both failed, were terrible, did nothing for sweating. Once Qbrexza was introduced, I was among the first to try it, and it truly works 100%. Although FDA approved for underarm sweating, it has stopped all my sweating. Since there is no generic, a month's supply costs somewhere around $700.00 if paying cash. Thus, insurance companies may not cover it at first if you haven't tried the cheap meds (referenced above) first. The best way to get it covered by your insurance is to have your dermatologist document in their progress note that you are a 4 on the HDSS (Hyperhidrosis Disease Severity Scale), Google it, and it will be one of the first results. This is a surefire way to get your insurance plan to cover it, especially when a prior authorization and/or medical necessity review is required. I've never had/heard of/learned of a solution to stop the Adderall sweats until this med came out."

10 / 10
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18 Report
  • Ria...
  • Taken for 6 months to 1 year
  • May 21, 2020

"HOLY MOLY. I used to use this product off and on because I would forget about applying it at night, but since quarantine hit, I decided to actually have a nighttime routine and I started using one pad a day regularly, and I noticed I stopped sweating... everywhere. It was so weird because I’ve sweat literally everywhere (mostly my underarms) for all of my life. I have always suffered from hyperhidrosis. Anyway, one morning I woke up with the WORST dry mouth I have EVER experienced. To the point where I was choking. My throat was so sore it was unbearable and my vision was so blurred. I am literally depressed because this actually stopped my sweating, but the side effects are just too much to handle."

6 / 10
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21 Report

Frequently asked questions

  • CCa...
  • Taken for less than 1 month
  • July 12, 2019

"Used to have to wear panty liners in my shirts to cover armpit sweat. Could be 100 degrees or -18 and I was pitting out! Been on for almost two weeks, soooooo much better!! I have had none of the side effects, not one. Try this product! It's a game changer!"

9 / 10
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23 Report
  • BKG...
  • Taken for 6 months to 1 year
  • September 18, 2019

"Have been using Qbrexza for six months for underarm sweating. Was working great. In the past two weeks, though, the side effects have come out of nowhere and hit me hard. Excessive dry mouth to the point of choking on food, urinary problems, blurred vision and inability to sweat. I was working out, doing my normal routine and spiked a crazy high fever. At first, I thought it was the flu, but I was fine the next day. Went to work out tonight, same thing happened and my coach noticed I wasn’t sweating. Stopping immediately. Will be calling my dermatologist tomorrow!"

4 / 10
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22 Report

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  • Mar...
  • Taken for less than 1 month
  • January 17, 2025

"Happy that something finally worked for my underarm sweating. But, as many have stated, side effects are not worth it. Urinary retention, dry mouth, blurred vision, and I don't sweat anywhere else. A shame side effects are so bad."

4 / 10
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2 Report
  • Chu...
  • Taken for less than 1 month
  • February 9, 2020

"Horrible!! Be careful if you use this on teenagers or young children. My daughter is 13, she used ONE! One! wipe, she ended up in the emergency room with bladder blockage, and the inside of her mouth turned white and super dry. She wasn’t able to eat or drink for over 48 hours. She was telling me she wants to cry, and she was so dry that no tears would come out. The medicine was over $500! Plus, the emergency room and the doctor's appointment to follow up, plus the medicine to get her back to normal, over $3000 in hospital deductible. I contacted the manufacturer, and I only got, 'I’m sorry that happened to her.' At least they reimbursed the medication, but not the rest. It's a very expensive risk and puts your child at risk, not worth it!!!!"

1 / 10
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20 Report
  • KTa...
  • Taken for 1 to 6 months
  • June 20, 2019

"The drug was great at eliminating my sweat problem, but at what cost? I experienced almost all side effects, even the severe. I got hives and was given several antihistamines from doctors because they couldn't figure out why they wouldn't go away. Later to find out that antihistamines have a negative reaction when taken with Qbrexza, so my hives just kept getting worse. Since then, I've experienced terrible dry mouth, urinary tract issues, and just this week began experiencing blurred vision. I went to the eye doctor, and he confirmed it was probably the medication since my pupils were incredibly dilated, which is also a side effect of the medication. I've never had an allergic reaction to any kind of medication. I wish I didn't have this experience with this medication since it does seem to work."

4 / 10
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17 Report
  • Jil...
  • Taken for less than 1 month
  • September 7, 2019

"Qbrexza works! There are side effects, but they are manageable. I use Qbrexza every other day and limit my swipes to one per area. I also use an all-natural deodorant (non-aluminum) to minimize dry, itchy skin. Since using Qbrexza, I am gaining a confidence that I never thought I would have!"

9 / 10
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17 Report
  • Rya...
  • Taken for less than 1 month
  • July 13, 2019

"Worked amazing from day 1, however, the side effects were horrible. Excessive dry mouth, couldn’t even eat. Dilated pupils, extremely sensitive to the sun. Also stopped sweating from everywhere, no matter how hot it was. This is scary and could lead to heat stroke quickly. My doc told me to discontinue immediately. Very upset by this as it’s the first thing that has ever stopped my underarm sweating."

4 / 10
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13 Report
  • TTa...
  • Taken for less than 1 month
  • July 6, 2019

"I used this 'off label' as a sample from my dermatologist for hyperhidrosis of the groin region. It was the easiest, non-irritating, best working product I have ever tried. I felt so free and confident to wear whatever type of pant I wanted without embarrassing sweat. I totally wish you could get this as a prescription for excessive sweating in the groin, but insurance only covers it for axillary hyperhidrosis. Totally bummed because it totally works!"

10 / 10
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12 Report
  • Ale...
  • Taken for less than 1 month
  • June 26, 2020

"First night with Qbrexza, just 1 wipe, and I am having half of the side effects: dry mouth, dry nose, itchy throat, blurred vision. This isn't worth the risk. Now I'm up at 3 a.m. in the morning writing this because I'm uncomfortable and can't go to sleep due to excessive dry mouth and nose... Ugh... Aggravating... I will never try it again."

1 / 10
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11 Report
  • Ste...
  • Taken for 1 to 6 months
  • July 19, 2020

"First day on Qbrexza, I woke up with a dried throat. Next day, I decided to use it around 5 PM and drink a lot of water, and I had no issues. I know side effects might vary, but 4 months in, and the only side effect is a dry throat once in a blue moon. Literally, the best thing ever, I can finally wear normal clothes."

10 / 10
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9 Report
  • Aan...
  • Taken for less than 1 month
  • February 6, 2021

"I used this medication for a week, and it really worked. However, on day 5, I got every single side effect to the extreme: dry mouth, throat, eyes, nose, blurred vision, distended bladder, and trouble urinating. I also stopped sweating from all other parts of my body, and when I exercised, my face got extremely red, and I began overheating. The benefits are absolutely not worth enduring the side effects. I won’t even continue trying to stick this out to see if they go away."

1 / 10
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8 Report
  • YaG...
  • Taken for less than 1 month
  • July 4, 2019

"So I have definitely noticed a decrease in underarm sweating, not as much as I wish, but I guess anything is an improvement. But I want to warn anyone that uses this, WASH YOUR HANDS!!! I put this on right before bed and forgot to wash my hands. I woke up in the night and realized my contacts were still in, so I took them out. Fast forward to the next morning, I looked in the mirror, and my eyes were dilated so big they looked almost completely black! Stayed that way almost all day, and going outside into the sun was almost unbearable. I had to wear my glasses and then sunglasses on top, not to mention I looked like I had been nose deep in cocaine that morning. Follow the directions!!!"

8 / 10
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10 Report
  • cas...
  • Taken for 1 to 2 years
  • October 26, 2020

"I had been on Drysol for years (I'm in my 30s); however, it was becoming increasingly difficult for my pharmacy to get, and the itching on application nights would keep me up. My dermatologist suggested Qbrexza, and I've been pleased, especially as I find the wipes far easier to apply than Drysol. I have a little itching after application, but it's nothing compared to what I experienced with Drysol. I did have severe dry mouth and throat irritation during the first week or so, but I increased my water intake, and this drastically decreased (possibly as my body adjusted to the medication). Everyone responds to medications differently, but for me, the benefits far outweigh the risks."

10 / 10
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8 Report
  • Lat...
  • Taken for less than 1 month
  • May 10, 2019

"Qbrexza started to work for my sweating right away. I did experience some dryness of the mouth and throat, but it goes away as the day progresses. Lots of water is a very important factor, the water helps with dryness and constipation. My experience is way better than I had expected from the medicine."

10 / 10
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9 Report
  • Oli...
  • Taken for 6 months to 1 year
  • May 23, 2020

"I use Qbrexza under my arms, and it has seriously changed my life. I’m allergic to aluminum, so most other options just made my sweating worse. I’m a young college student, so I also didn’t want to try any pill that might have other lasting side effects. I think it’s important to follow the directions EXACTLY. Only one swipe per area, wash hands immediately. Doing anything outside of that exactly has given me the side effects others have complained about. I did have dry mouth when I first started it, but it went away within about a week of use. I did sort of struggle to get my insurance to cover this expensive drug, and it had to come from a specialty pharmacy, but it’s been completely worth it. I can wear sweaters, and I don’t have to wash the straps of my book bag of sweat anymore."

10 / 10
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8 Report
  • Jul...
  • Taken for 1 to 6 months
  • April 7, 2020

"I have been using Qbrexza for a few months now, and it works great! I was using it every day and did experience dry mouth at times, so I switched to every other day, and it made a world of difference! I have even found that lately I can go a few days or even a week without using it, and I still stay dry. I would recommend spacing it out if the side effects become too much. Definitely wear gloves when you apply it to avoid unnecessary contact with other parts of your skin."

10 / 10
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7 Report
  • Smi...
  • Taken for 1 to 6 months
  • October 6, 2021

"It works… if you can afford it. After my samples ran out, my insurance checked, Monat denied my prior authorization. The pharmacy wanted $1,000 for a 30-day supply. You read that right. $1,000 for something the size of an alcohol wipe. So frustrating. I finally find something that works, and it’s so overpriced. I guess I’ll just sweat until 2033 when it goes generic."

9 / 10
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5 Report
  • Cur...
  • Taken for less than 1 month
  • March 3, 2020

"I've experienced severe hyperhidrosis for over 20 years. My dermatologist had a sample and suggested it. I followed the instructions, applying to both underarms in the late afternoon. I woke up in the middle of the night with a major headache, dry mouth, and throat that felt like it was swollen. I drank water, and it was painful going down and caused a sore throat. I will say that it was effective the following day with no sweat. However, I had to leave work due to fatigue. This product works without question. I will not take it again because the risks outweigh the reward. I would recommend going with a smaller dosage to minimize the symptoms."

5 / 10
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6 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 17, 2023

"This medicine was the best until it turned on me. I started having blurry vision for about 2 weeks, to the point I was seeing double and I couldn't work or do anything normal. This all started in August 2022, and today, March 2023, I'm still having to go to the eye doctor. I've been there and spent a lot of money to figure out what's happening with my eyes. This drug made me develop some sort of 'bump' in the back of my eye, and I ended up having to have a brain MRI. Luckily, that came back clear for tumors/cancer, but it still hasn't been a pleasant experience. I haven't been able to wear contacts like I have my whole life until March 2023 since my eyes are still slowly coming back to normal. My scans at the eye doctor are getting better, so things are looking good and shouldn't have any more setbacks, but this drug totally destroyed my eyes for a while before we figured out what was going on. I DO NOT recommend these wipes to anyone."

1 / 10
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3 Report
  • NoS...
  • Taken for less than 1 month
  • January 8, 2022

"Works wonders, but it’s not tolerable due to the side effects. By far, the worst side effect is the dry mouth/throat that lasts for HOURS. I could barely eat anything because the lack of saliva almost choked me. Even WATER was tough to get down. I also experienced annoying dry eyes and blurry vision. I received 3 sample boxes containing 5 cloths in each box for free from my dermatologist. Side effects kicked in after the first use. The crazy thing is I cut 1 cloth into 8 pieces as instructed and used 1 piece per underarm… that was still too strong! Good luck to those who can tolerate this because it’s not worth it for me. Going back to Botox in my armpits. Costs around $500 where I’m from and lasts about 5 months for no underarm sweating."

6 / 10
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4 Report
  • Lut...
  • Taken for less than 1 month
  • November 9, 2023

"This product works as other users had indicated, but I am starting to experience blurry vision and dilated pupils to the point where my eyes look scary. Although the product works, the issues with my eyes have me creeped out, so I’m going to be stopping use of this product."

5 / 10
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2 Report
  • Sun...
  • Taken for less than 1 month
  • July 3, 2021

"My dermatologist told me about the wipes. I never knew about them, she gave me 2 weeks of samples, and I literally noticed the difference within the first 3 days. I have suffered for 18 years, and now it feels amazing to be without dry underarms! I can wear white shirts again, I can wear anything! However, I do notice the dry mouth at times. Just drink lots of water, and ONLY wipe once per arm. When I wipe more than once, the dry mouth is worse. Truly a change in my life."

10 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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