Glecaprevir / pibrentasvir for Hepatitis C User Reviews
Brand names: Mavyret
Glecaprevir / pibrentasvir has an average rating of 8.4 out of 10 from a total of 337 reviews for the treatment of Hepatitis C. 79% of reviewers reported a positive experience, while 8% reported a negative experience.
Reviews for Glecaprevir / pibrentasvir
- LAM...
- Taken for 1 to 6 months
- September 21, 2018
Mavyret (glecaprevir / pibrentasvir) "First, I have to thank this forum. Talk about doing a service to the public. I ended my treatment 4 days ago of 8 weeks of treatment. And my results were negative for the Hep C virus. Found out today, it means nothing till you take another blood test 3 months after you end treatment of Mavyret. If it worked. I am going to post one more time after this post. It's just super sad, and there are mass media commercials that do not explain the Hep C symptoms. Remember when you do not look sick, no one believes you. With my experience with Hep C, depression started first. Seeking help from DBSA (Depression and Bipolar Support Alliance) in group meetings. Then the fatigue set in, I was in bed over 20 hours a day, over 4 days a week, wishing I was dead. Wanting to kill people I love, which would only be acting on the temporary virus, Hep C symptoms. No one properly explains the symptoms of Hep C and how bad it is. Hopefully someone understands my message."
- Anonymous
- Taken for 1 to 6 months
- August 23, 2020
Mavyret (glecaprevir / pibrentasvir) "After reading all the Mavyret reviews, I made sure I took it at bedtime with a bottle of water. I am a 30-year-old male, 5'10", 160 lbs. I had no side effects at all. I just finished my 8 weeks, and after my follow-up test, I am negative for Hep C."
Frequently asked questions
- What are the new drugs for the treatment of hepatitis C?
- Does Mavyret cure hep C (HCV)? What is the success rate?
- Can you take antibiotics with Mavyret?
- Does Mavyret cause itching?
- Mrz...
- Taken for less than 1 month
- August 2, 2020
Mavyret (glecaprevir / pibrentasvir) "I am on my second week of Mavyret treatment for hep C, Genotype 4a, and have had Hep C for over 30 years. I have good days and some weird days! I take my meds at 11:30 AM with food. Definitely eat! Side effects for me have been anxiety in the midst of the COVID virus (I live in FL), waking up at 3-4 AM with anxious thoughts, some fatigue during the day, and a very slight headache on and off. Hoping for a cure at the end of my 8 weeks! God bless everyone on this journey."
- Mic...
- Taken for 1 to 6 months
- March 13, 2019
Mavyret (glecaprevir / pibrentasvir) "Coming back 8 months later to speak about experience. Did a 2-month treatment of Mavyret. My viral load dropped significantly. Went for ending blood work (still had a viral load less than 12) worst part, medication was done. I was devastated. I assumed I didn't clear. The doctor said, 'the medication still works. Come back in a month for another test.' I had little hope. Went back in a month, UNDETECTED. Just did my six-month test.. UNDETECTED. It's safe to say, my Hepatitis C is gone. The doctors feel safe to say it. Point being.. When your meds are done, the medication still continues to work for upwards of a month. If your viral load is low at the end, chances are, it will show undetected a month later. Do! Not! Give! Up! Have hope! When you have nothing else, you still have hope."
Are you taking this medicine?
Your review helps others make informed decisions.- Jea...
- March 13, 2020
Mavyret (glecaprevir / pibrentasvir) "I'm from Germany, got HepC in the mid-80s. Happy there finally is an alternative to Interferon/Ribavirin! Started my 9th week (of 12) today. Only had very mild nausea and very mild diarrhea after the first doses, for 3-5 days, but did not feel sick or otherwise unable to work. Also had sudden fatigue that quickly disappeared after I had some rest. After the first week, I hardly even noticed I was on medication. Virus load was tested after W4 - and all HCV had gone, a miracle! Mid-July, I will have my SVR12 test. So let's keep spirits up, folks! Whatever the side effect - HepC has such a bad prognosis, high risks and may also have various co-diseases. There's rashes and joint/muscle pain (which I have had coming and going for some years now), and there may be many more. Hope for alleviation of my joint pain after the medication. I'd like to encourage everyone to go for the therapy. Let's get rid of the virus, and be free to live a healthy life!"
- Was...
- January 14, 2020
Mavyret (glecaprevir / pibrentasvir) "I have had Hep C for 25 years. Stage 4 cirrhosis in the liver. I was only able to tolerate the medication for 5 weeks and 5 days. Basically, it gave me really dark thoughts I've never had before or since stopping the medication. My doctor agreed that everybody is unique but my situation was unusual, and I had to stop the medication. The other side effects I experienced were nervousness, loss of appetite, muscle aches, just all-around feeling physically nasty, but it was the mental side effects that I had the most issues with. I've actually read reports from the VA that several people have experienced the same suicidal thoughts. My doctor informed me that I am most likely not cured because I didn't complete the 12 weeks. I was told I'd have to do another medication if I tested positive for Hep C. Today, I called for the results... I'm cured."
More FAQ
- Sur...
- Taken for less than 1 month
- January 29, 2020
Mavyret (glecaprevir / pibrentasvir) "I started Mavyret 7 days ago. I feel great. I have found out that to keep the nausea away, it is best taken at night with food a few hours before bed. Drink plenty of liquids and eat your meals, do not skip eating. I take 40mg of Omeprazole in the morning with a large glass of water. I have survived Esophagus Cancer and am very sensitive to medication, so I was worried about the nausea others have reported. I tremble a little with the medication, so I increased my liquids and it stops. I hope whoever reads this tries the medication and gets rid of HEP C."
- Fra...
- October 31, 2019
Mavyret (glecaprevir / pibrentasvir) "I looked at other reviews before taking this medication, and it made me not want to take it. I have had no problems. No side effects whatsoever. I have been taking this for a few weeks now. Do not let the reviews turn you off of this medicine. I will write another review when complete."
- 4ev...
- Taken for 1 to 6 months
- February 28, 2020
Mavyret (glecaprevir / pibrentasvir) "I am a 34-year-old female who has had Hep C for 12 years now. I quit smoking cigarettes two years ago and do not drink. My blood work before starting the medicine showed no signs of liver scarring. I decided to take the pills at night after eating dinner. I drink plenty of water every day and eat pretty healthy. I have 5 more days left of the medicine, then I am done! I did not experience any side effects, and my recent blood work was negative for the Hep C virus!!! I go back in 12 weeks to confirm a cure!"
- Kaj...
- Taken for less than 1 month
- December 22, 2019
Mavyret (glecaprevir / pibrentasvir) "Before taking this medication I read all the comments on this post... they literally had me scared to death! So scared that I postponed starting the medication for almost a week. I’m now 1 week into the medication and I’ve had zero side effects so far. At this point I’m starting to think (for the biggest part) only people who had negative experiences with it cared enough to review it."
- Ken...
- Taken for 1 to 6 months
- March 10, 2020
Mavyret (glecaprevir / pibrentasvir) "Just finished my 8-week treatment with Mavyret. Had no side effects. Doctor called and said no Hep C virus was detected. So thankful. Will go back to check again in July. I had Hep C for 28 years and always felt so tired. Hoping now that it's gone, I can start feeling better, enjoy life, and not want to go to sleep all the time. Feeling grateful..."
- gr8...
- Taken for 1 to 6 months
- November 7, 2019
Mavyret (glecaprevir / pibrentasvir) "I have had Hep C since 2000 but did not have insurance that would cover Mavyret until recently. The side effects were not a concern to my doctor. I was seriously ill with bone pain, nausea, fatigue, and headaches. Worst of all, about halfway into treatment, I started getting severe panic attacks - I had never had a panic attack in my entire life. My doctor said it had nothing to do with the medication. Uh, yes, it did. I also developed red lesions on my hands, feet, and legs that have not stopped forming even after three weeks of being off the medication! My doctor says that it is psoriasis, which I have never had as well. I am still suffering with the anxiety and skin lesions today. I hope it worked so it is worth all these side effects. I find out in January if I am free of Hep C, but my mid-treatment blood work showed good signs, so pray for me, pray these lesions go away too, please! Thanks for all the posts and support. I do not feel so alone."
- Lol...
- January 8, 2020
Mavyret (glecaprevir / pibrentasvir) "Eight-week course of Mavyret. Side effects weren’t too bad during treatment, but immediately after the course of meds was finished, I was suddenly slammed with severe joint and muscle pain, along with extreme fatigue. Five months out, I am barely able to function. I went from swimming a mile 3-4 days a week to barely being able to swim 1/4 mile once a week. I also did yoga 3-5 days a week for 90 minutes, now, 30 minutes every day IF I’m lucky and have low enough pain, and fatigue doesn’t have me glued in place. This is a BAD drug. I don’t care if it cures every single thing that ails you, it will leave you so debilitated you’ll barely be able to function. I’m keeping my eye out for a class action suit."
- Vic...
- Taken for 1 to 6 months
- October 23, 2018
Mavyret (glecaprevir / pibrentasvir) "Love this group. I have been reading this for a few weeks now. I am a 56-year-old male that has Hep C type 1 for probably 40 years. After being so sick I couldn’t work anymore, went to the doctor and was diagnosed. 13.7 million viral load. I start treatment on Friday, two days ago. Very nervous and high anxiety. I feel my liver twinging every morning for hours, I just lay around sick every day. Also was diagnosed with fatty liver. I'm so hopeful, so want life back. Nobody gets this disease or understands - unless you have it. I never did. Love to you all! Victor Now for my update! Update! Week 2 of medication. Still aches and pains, some depression. But it’s all poos and giggles now! I have worked a few hours for the last 3 days! Another update! Week 5 blood came back undetected! The world looks different now. Just stunned! Have been doing work again, slowly. Praise the Lord and Mavyret!"
- Rol...
- Taken for 1 to 6 months
- October 14, 2019
Mavyret (glecaprevir / pibrentasvir) "I finished week 8 of Mavyret on July 17th. Blood tests show no Hep C!!! I must have had it since spring 1981 from a dirty syringe my 'friend' left under my sofa. I was stuck by it the same day he used it and 'hid' it there. Side effects are still happening; severe fatigue, slowly getting better. My doctor told me to hang in there, as 2 - 3 months of side effects after finishing the meds is not uncommon. I felt better just having him tell me that! He also said, '2020 will be one of the best years of my life so far.' So grateful for this medicine, prayers for all of us... PEACE."
- Sha...
- Taken for 1 to 6 months
- June 2, 2020
Mavyret (glecaprevir / pibrentasvir) "I just finished my 8-week course. The side effects are minimal but still suck, it really depends on your lifestyle choices. I'm an avid coffee drinker, so guess who dealt with headaches every day despite how much water I drank. The nausea leveled out, and FYI, the bigger the meal is, the better. You get much fewer side effects that way. I took it with a glass of milk. The thicker liquid gave the medication a better absorbency, which = fewer side effects. I have alopecia areata and had thinning of hair during treatment, but I expected that due to underlying illness. I couldn't wait to finish this because the side effects basically got on my nerves, I was tired of being tired, but they weren't unbearable. I could still function fine. I just kept in mind the day I got to 'cross the finish line': a healthier version of myself thanks to Mavyret. I was non-detected at my 4-week visit, btw. Despite some mild side effects that get on your nerves, it's totally worth it, your future self will thank you for doing this."
- Sum...
- October 20, 2019
Mavyret (glecaprevir / pibrentasvir) "Yes, finally a drug that can cure me, and it did just that. However, the side effects they don't tell you about, and I called them about it, could have killed me. I was getting severe itching and bruising, told my MD who put me on Prednisone, and it helped until my last week and a half. I had a bad sore throat, trouble breathing. Within 2 days, I was in critical care, and my family was called, it was that bad. Taking both meds, the Mavyret and Prednisone, was causing me to get sick. I had pneumonia and needed assistance with breathing and honestly felt it was only time before I'm gone. I had a procedure where they go into my lungs to get gases and tissue, which caused bleeding every time I coughed, extremely painful. Long story short, 5 weeks later, finally going home. Yes, Hep C free too, but the combination of both meds could have taken my life. Not only did the hospital, MD, and I notify the manufacturer, nothing was done to show these 2 drugs combined could kill you."
- Aan...
- Taken for less than 1 month
- February 28, 2020
Mavyret (glecaprevir / pibrentasvir) "I'm only on my second day of Mavyret, and it is kicking my butt. I'm not a complainer, but this medication really makes me feel out of it. Nausea, dizziness, headache, and tiredness are also side effects I'm having. I had no liver damage and had a pretty loud viral load. I'm 26 and obviously will continue treatment to cure my hep C, but it's not a pleasant feeling. I'm currently taking my medication in the morning with light food. Maybe I should switch to before bed? Is that better? 7 weeks to go! It'll be fine."
- Tin...
- Taken for 1 to 6 months
- February 25, 2020
Mavyret (glecaprevir / pibrentasvir) "Update... It has been 6 months since my last treatment for 8 weeks. Lab test today non-detectable. Yes, some have side effects, others none. Drink lots of water and eat a good meal. You have no choice but to take this medication. You can do this ~ Good luck!!"
- jam...
- Taken for less than 1 month
- February 9, 2020
Mavyret (glecaprevir / pibrentasvir) "I am starting Mavyret on March 3. I've had Hep C for probably 50 years. Got it in the military. They tell me my liver looks practically normal with an extremely low viral load but suggest I still do the treatment. My question is if you have to work from 8 AM to 3 PM, what is the best time of day to take this so you might experience the least amount of side effects during that time period? I could probably handle harsh side effects if there are any, but someone tried to warn me about the possibility of this drug after treatment has finished causing heart conditions. Has anybody had any heart-related problems after taking this drug? Thank you very much."
- Pau...
- Taken for 1 to 6 months
- January 21, 2020
Mavyret (glecaprevir / pibrentasvir) "OK, so now I'm a month in. My insides have been a bit soft, but I've found that if you take your Mavyret while eating, then it's not so bad. I've had a bit of fogginess in the brain and bouts of fatigue, waves of depression and anxiety. My advice is don't dwell on the side effects, it'll just make them worse. Let's face it, most of us got Hep C one way, and we know that when you were hanging, if you just got on with things, it wasn't nearly as bad as when you sat around feeling sorry for yourself. Compared with Interferon, this is nothing."
- NW ...
- Taken for less than 1 month
- September 1, 2019
Mavyret (glecaprevir / pibrentasvir) "I have used the Mavyret for 2 weeks now. I get this 'psyched out' feeling like I am worrying and self-absorbed, scared I can't keep taking the med if it worsens. I go to the gym and exercise to help the muscle pain, fatigue, and headache symptoms. I am drinking a ton of water. I am so sensitive to medicine, but I am convinced I will get through this treatment. I have had hep C for over 45 years and I want to cure. May the Lord grant me a miracle."
- Lol...
- Taken for 1 to 6 months
- August 11, 2019
Mavyret (glecaprevir / pibrentasvir) "11 days post-Mavyret treatment and I feel like garbage every day. Extreme fatigue, muscle weakness, and joint pain! I hope this subsides soon, but from what I’ve read, side effects like this could last up to a year! I’m sorry I ever took the treatment. I never felt this bad in 40 years of being infected! I thought this was going to be good, but so far it's unbelievable how bad I feel. The Mavyret company says, “no side effects like that ever came up in clinical trials.”"
- Cat...
- August 17, 2019
Mavyret (glecaprevir / pibrentasvir) "So my PCP and then GI doc both assured me side effects with Mavyret are negligible. Nothing could be further from the truth; and they seem to be cumulative. Not much for the first week, then nausea to the point where I couldn’t eat. Next came the headaches, which were bad enough, but then came the fatigue/bone tired/flu-like feeling, including brain fog. I am almost six weeks into treatment, and the pattern seems to be I can “function” one day, followed by a day when I can only get out of bed to get to the bathroom. I didn’t research side effects of this drug because even though I am a pretty stalwart person who doesn’t give in to illness without a fight, I also didn’t want to be suggestible. Multiple calls to my docs have been futile. I have been told multiple times to “suck it up” and finish treatment."
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Mavyret (glecaprevir / pibrentasvir) "I normally never write reviews but felt I needed to considering people are reading this when deciding to take the Mavyret. I, myself, did so before taking the medication and found myself hesitant and nervous because I am super sensitive to medication. Tomorrow will be my fourth week of taking it and it has been a lot easier than I had anticipated. My side effects have been dizziness, trouble focusing, coldness, slight nausea, tiredness. I had some anxiety which is now gone. The dizziness has decreased dramatically and I can focus much better now. My body just needed to acclimate to the meds. If I can offer advice to anyone who is reading this is to prepare. Drink 16 cups of water a day. Eat crackers for nausea and eat a big meal with the meds and rest when your body needs it. Take care of your body so it can take care of you. I can only speak to my experience of the medication. For me, it has been a lot easier than I had anticipated. Don't let fear stop you. You can do this."