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Symbyax for Major Depressive Disorder User Reviews

Symbyax has an average rating of 7.0 out of 10 from a total of 8 reviews for the treatment of Major Depressive Disorder. 50% of reviewers reported a positive experience, while 25% reported a negative experience.

Symbyax rating summary

7.0/10 average rating

8 ratings from 8 user reviews.

Compare all 56 medications used in the treatment of Major Depressive Disorder.

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  • GregD
  • Taken for 1 to 6 months
  • February 18, 2017

"Symbyax has changed my life. I have battled treatment-resistant depression, anxiety, paranoia, and bipolar 2 for all of my life. I'm 46 years old. Since age 18, I've tried probably every SSRI there is, including Prozac by itself. I won't list all the SSRIs and mood stabilizers I've tried because it would be a very long list. Nothing ever worked. I had a great career, but my problems have caused me to lose numerous jobs. The only time I felt how I thought I should feel was when I was on painkillers for surgeries; however, I knew that was not a treatment or sustainable. My doctor prescribed Symbyax (Prozac + Zyprexa). Within a day I was experiencing life the way I've always wanted to. I'm energetic, social, engaged, happy, etc. Great medicine"

10 / 10
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69 Report
  • Jimmy
  • Taken for 1 to 6 months
  • August 30, 2018

"I started taking the symbyax 6-25 about 2 months ago. I was severely depressed and having really bad anxiety and panic attacks prior to starting it. It started helping after a week but I was still having panic attacks. My doctor upped my dose to 6-50 mg a month ago and wow I feel amazing. No more depression and my panic attacks/anxiety are gone. This is by far the best medication I’ve taken for my disorders. All my friends and family say I’m a totally different person in a good way."

10 / 10
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49 Report
  • Symbyax...
  • September 3, 2015

"I have been on Symbyax for about 8 weeks now. The doctor upped my prescription to 6mg/50mg. It does make me eat all the time. I can't stop munching. This medication makes me feel a little better but it didn't last very long. I'm slowly declining again. Zoloft seemed to work but my doctor didn't think that was going to help me in the long run. I am having short term memory loss due to extreme anxiety. The Symbyax seems to make it worse. I still don't know if I like it or not."

7 / 10
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19 Report
  • Ted...
  • Taken for less than 1 month
  • November 5, 2019

"So far so good on Symbyax after only 4 days. My depression is not as prevalent and I haven’t had anxiety. My medication specialist prescribed the 2 meds separately to save on costs. Instead of $200 I paid $17 for them separately. So far I haven’t been overly hungry but it’s still early. I only gave it an 8 because it’s still early but I’ll revise my review in a month."

8 / 10
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11 Report
  • Egghead...
  • Taken for 2 to 5 years
  • March 30, 2022

"I took Symbyax for 6 years. The last year was awful because I developed a seizure disorder. The ER doctor told me it was the medicine causing my problem. My GP wanted to double my dose! I quit cold turkey because I could absolutely not handle any more seizures. Unfortunately, after quitting I went through hundreds of seizures over the next several months. The seizures gradually subsided the further away I got from my last dose. I believe it was the Zyprexa in the Symbyax that ruined my life! After nine months of being drug free but still completely devastated from my experience, I went to a different doctor and was prescribed Lexapro. The Lexapro helped for about 2.5 years then lost its effectiveness. I weaned myself off Lexapro very slowly over months then quit. Its been three months now and I am finally starting to feel better, yet I am nowhere near well! I will not take another antidepressant without a fight from here on out. I have had enough! Good Luck!"

2 / 10
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4 Report

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  • TheOn...
  • Taken for 6 months to 1 year
  • August 6, 2021

"It made my face swell up so bad my eyes looked barely open, they were so puffy. And this was after taking it for over 6 months. Side effect just came out of nowhere. I now take Prozac 40 and Lamictal 150 and feel so much better. And it didn’t really seem to help much with my depression, I was still laying in bed and sleeping most days and nights although maybe slightly less than unmedicated."

2 / 10
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3 Report
  • tja
  • October 17, 2016

"This medicine has worked wonders for me! Only problem is the weight gain - I have gained almost 40 lbs in 3 months."

7 / 10
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26 Report
  • Descon
  • January 31, 2024

"I can say that this medicine is really a lifesaver. I am very satisfied. It is great to use it under the supervision of a doctor."

10 / 10
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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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