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Efudex User Reviews & Ratings (Page 5)

Efudex has an average rating of 7.5 out of 10 from a total of 121 reviews on Drugs.com. 66% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Efudex

  • Aussi...
  • Taken for less than 1 month
  • September 7, 2021

For Actinic Keratosis "Used Efudix full face treatment for AK and Bowens disease. Twice daily for three weeks. I was one who suffered severe reaction. From week two I suffered intolerable pain for three weeks. My face was a total mess of raw flesh. Sleeping impossible. Pillow and sheets stained with body fluids seeping from face. Sent me into a depression for 3 months. Worst experience of my life. Having said that the results were fantastic. Baby smooth blemish free skin [age70]. I am glad I perserved BUT I recommend the following. Do not do the whole face at once. Break it up into halves which reduces pain and makes sleeping easier, That pillow really hurts. Do not get it in eyes nose mouth genitals etc as believe me you will suffer! Put only thin film on as thats all you need. If Doctor states used for three weeks but you start to ulcer and erode at two weeks then stop because your done, don't extend the agony.Mine is the worst case scenerio. You experience may vary. Good luck."

10 / 10
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  • Jim
  • Taken for less than 1 month
  • February 8, 2022

For Actinic Keratosis "As expected this treatment is be Horrendous .Week 1 was not too bad Week 2 was extremely difficult, lack of sleep etc. Week 3 Truly awful ! Extreme pain, care must be taken when showering, I used lukewarm water on my face, I found this helped but then the skin went tight .After applying Efudix, I waited an hour or so before applying a moisturiser ( Nivea for men sensitive alcohol free) Sleep is extremely difficult due to the terrible itch - scratch - itch ! Week 4 .I had to stop using Efudix ! swollen face, half closed eyes ,however it has definitely worked with blistering ,weeping and peeling beginning. Because of the swelling around my eyes, I rang my Doc and we agreed to cease any further application as the Efudix has done the job! I am now experiencing bouts of severe itching - tried all sorts of lotions and potions but alas no relief, Nivea seems to give a little relief . I've read you often worse when you stop using Efudix and it's true!"

9 / 10
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6 Report
  • carol
  • Taken for less than 1 month
  • April 13, 2024

For Keratosis "I was prescribed Efudex for erosion on my face, used it every day for 3 weeks. My skin didn't go red or sore. I don't know why. I thought it can't be working as I didn't have any reaction to it, but it has worked; the skin cancer has gone now."

10 / 10
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1 Report

Frequently asked questions

  • Mary
  • Taken for 1 to 6 months
  • January 26, 2022

For Basal Cell Carcinoma "Using Efudex for Basal Cell Carcinoma (BCC) on my nose. Have finished 24 days and plan to go for 4 more days. My dermatologist feels if it hasn’t done the job then it most likely will not work. My nose has been red since week one then the affected area scabbed over during week two and three it was uncomfortable but tolerable. Since I began week four the pain has become intense at night almost intolerable. I am trying to soldier on but it is very stressful. I am using Tylenol and Benadryl but nothing eases the pain but ice packs. It feels like someone is driving needles or glass in my nose it’s Brutal. My phone doesn’t recognize me anymore."

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  • Female
  • Taken for 1 to 6 months
  • February 17, 2023

For Keratosis "I used Efudex for 6 weeks in total. I did stop the treatment at intervals when the blistering became too bad. I used it at night and put make up on during the day to cover all the redness. It is the worst experience I have had with my skin. But looking at my face now, it was worth it. It is 2 months since I stopped and I still have slight redness in certain areas. However the improvement in my skin has been wonderful. I will always use 50 factor suncream when I go out. Heliocare is very good. I hope and pray that I never will have to use Efudex again."

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Are you taking this medicine?

  • Rita
  • Taken for 1 to 2 years
  • October 23, 2023

For Skin Cancer "A sun worshipper from my teen years and up... I had/have spots of skin cancer on my face/arms/chest. I was sent to a plastic surgeon and had a spot surgically removed from between my brows (not a good experience). I am now using Efudex. I am tolerating the pain, itching, and side effects, but I find it helps. I have used it on my face, arms, and chest with good results. I have been using it intermittently for 1.5 years and will continue until my skin cancer is gone. It may be a while."

9 / 10
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  • Jennie
  • Taken for less than 1 month
  • June 3, 2023

For Keratosis "Used on nose, cheeks, and chin every night for 18 nights when scabbing became apparent, so stopped using. From today 3 June, I use canestan steroid cream on the affected areas. Also using oatmeal cream which is very mild. Areas are very red and unsightly with scabbing and some tightness. Redness and tightness have moved towards my eyes and this is quite uncomfortable. Persevering. Can’t comment on the outcome as the process is still ongoing."

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  • Dolly
  • Taken for 1 to 6 months
  • February 17, 2023

For Keratosis "I used Efudex for 6 weeks in total. I did stop the treatment at intervals when the blistering became too bad. I used it at night and put make up on during the day to cover all the redness. It is the worst experience I have had with my skin. But looking at my face now, it was worth it. It is 2 months since I stopped and I still have slight redness in certain areas. However the improvement in my skin has been wonderful. I will always use 50 factor suncream when I go out. Heliocare is very good. I hope and pray that I never will have to use Efudex again."

8 / 10
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  • kzn
  • Taken for less than 1 month
  • October 8, 2021

For Basal Cell Carcinoma "I was told it won't work on a squamous carcinoma. Applying to the tip of my nose for 3 weeks and only slightly red with no discomfort, hoping its not irritating a squamous cancer! on my face for 10 days so far and red and flaky but no real discomfort. some the stories on here are horrific but so far so good. will do one side of my face and evaluate the benefits. big fan of freezing them off so will weigh it all up."

5 / 10
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  • Militza
  • June 17, 2024

For Keratosis "This is my 3rd time using Efudex cream. I have been told by my dermatologist to use Efudex cream 2 times a day for 2 weeks on lower lip, forehead (1 spot), between upper lip and nose (1 spot), and both hands. I have very fair pale skin. My skin reacted really quickly to the cream. In 5 days, my skin was red with blisters and itchy, very uncomfortable. Now I am on day 10 and my hands are swollen, itchy, with scabs, very dry, and uncomfortable. I am applying fresh aloe vera gel from my yard 2 to 3 times a day. I am not sure I can make it to 14 days. I will write to let you know the results."

8 / 10
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  • Jacki
  • Taken for 1 to 6 months
  • February 21, 2024

For Keratosis "Prescribed once a day for 3-4 weeks. I used it all over my face and chest... by day 13, I needed a break and stopped for two days! 21 days in and my chest is very painful, raw, swollen, and feels like paper cuts opening all over when I move. My face hasn't been too bad pain-wise, but I'm scaring not only the children but adults too ;-) Try to keep the cream away from the sides of the nose as it will crack the thin layer of skin that joins to the upper lip, and it's not pleasant! Not sure if I've gone as far as I'm supposed to, but the sores are starting to peel... I don't want to do this again and get it right the first round."

8 / 10
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  • Anonymous
  • May 4, 2018

For Actinic Keratosis "I work for a dermatologist. In order for Efudex to react, sun damage/AK's, cancer should be present. Undamaged skin will not react to Efudex."

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110 Report
  • olyfo...
  • September 25, 2008

For Skin Cancer "This product works very well to eliminate skin cancers. It becomes quite irritating after a few days, and very irritating at about 10 days, but it gets rid of the skin cancer in a couple of weeks."

9 / 10
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177 Report
  • Deewi...
  • Taken for less than 1 month
  • September 17, 2017

For Actinic Keratosis "I have a question, not comment, please. I'm on day 6 of 14 days of application. No reaction. Is this normal? I'm applying a thin layer 2 times a day. Am I doing something wrong or is this normal?"

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  • Trueser
  • August 5, 2015

For Keratosis "Worked great for me, some pain but when I was done my face was like a baby's butt. Stay home for 30 days"

10 / 10
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106 Report
  • Anonymous
  • February 12, 2009

For Keratosis "Efudex works great to eliminate actinic keratosis. I have used it before and unfortunately am using it again. It becomes VERY unsightly.. blotchy, swollen, very painful, etc, but it works."

9 / 10
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158 Report
  • The...
  • April 8, 2016

For Keratosis "Can someone help me? I have been using Efudex once a day for 5 weeks and nothing is happening. Wondering if I should try using it twice a day or wait until I see my doctor?"

1 / 10
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96 Report
  • Sun...
  • Taken for less than 1 month
  • January 2, 2020

For Basal Cell Carcinoma "Have found using efudux apply only every 3 or 4 th day seems reaction not so bad and it will do the job in same amount of time .. works for me"

7 / 10
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35 Report
  • Lee
  • Taken for less than 1 month
  • May 3, 2020

For Actinic Keratosis "I just started I’m on day three I am absolutely terrified "

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25 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 10, 2019

For Keratosis "Efudex was extremely painful. It affects cancer spots. Well I guess that is all over because my entire body was inflamed."

4 / 10
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24 Report
  • Smand
  • Taken for 1 to 6 months
  • August 30, 2016

For Basal Cell Carcinoma "I have BCC on my upper arm and SCC on upper left hand. Unfortunately after 6wks of treatment twice a day the cream didnt work. So disappointed and im now scheduled to have both surgically removed."

1 / 10
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32 Report
  • APOC-...
  • Taken for less than 1 month
  • September 9, 2021

For Keratosis "Does not work. Save your money. No change at all after using for 10 days."

1 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.