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Ezetimibe for High Cholesterol User Reviews (Page 4)

Brand names: Zetia

Ezetimibe has an average rating of 3.8 out of 10 from a total of 136 reviews for the treatment of High Cholesterol. 24% of reviewers reported a positive experience, while 63% reported a negative experience.

Reviews for Ezetimibe

  • Riodosa
  • Taken for 5 to 10 years
  • August 4, 2018

"I have been on this number of years - maybe 7. I think the Ezetimibe was effective on reducing the cholesterol as designed however, I have had bouts of diarrhea for years like my stomach explodes and out it comes. The doctors have not come up with a cause and/or a solution. Lately I have reason to believe it is caused by the Ezetimibe that I take. It seems to come on me about 2 or 3 hours after I take it. Anybody else have this problem?"

6 / 10
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38 Report
  • ejn
  • Taken for 1 to 6 months
  • March 18, 2017

"I have used this for a few months as I cannot take a statin due to muscle pains. During this period I developed a stiff shoulder that later progressed to a frozen shoulder. Worse, I had problems with focussed thinking, and because of my lack of focussed thinking I only noticed this at 6 weeks. As I am a teacher, I immediately quit using it. I was lucky this happened in the school holidays. I have no idea what it did for my cholesterol, as the second side effect I noticed was such that I felt unable to continue it."

2 / 10
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44 Report
  • JJano
  • Taken for less than 1 month
  • November 4, 2020

"I was on Zetia for a month but my hip burned so I stopped, much like other statins I had tried. I tried it again later and after a month both my hips burned. I stopped Zetia and the burning improved. It has been 6 months and my right hip still burns, and sometimes my left. I am done with statins. No drug is worth side effects like this. I will exercise more."

1 / 10
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26 Report

Frequently asked questions

  • debs
  • Taken for less than 1 month
  • November 9, 2019

"My dr warned me that I may get stomach problems on ezetimibe , but I wasn't expecting the runs for hours on end and stomach pain. I've stopped it as I'm not sleeping and I'm constantly burping and it tastes awful, I messed up my bed and clothing."

1 / 10
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31 Report
  • Sitinin
  • Taken for 2 to 5 years
  • February 22, 2018

"Was on Zetia 10mg daily for four years. Underwent numerous scans, testing, Ultrasounds & vascular studies to determine why I was having severe leg cramping every single day ( worse at night ) I discontinued Zetia by myself and legs had 100% return to normal. Unable to take statins due to joint pains but was assured this med was not the same."

2 / 10
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39 Report

Are you taking this medicine?

  • Mare
  • August 1, 2020

"Been taking ezetimibe 10mg about 3 weeks. I do get occasional diarrhea but my biggest problem is the bloating my stomach looks like I'm pregnant and I hate that feeling. I don't have any other symptoms."

5 / 10
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27 Report
  • Milag...
  • Taken for 1 to 2 years
  • December 6, 2019

"My Doc believed my LDL and total cholesterol were too high. I was on Simvastatin 40mg. He added a script for 10mg Ezetimibe. 3 months later on Simvastatin 40 and Ezetimibe 10 my total Cholesterol improved 216 > 116. LDL improved 137 > 46. I was on Paleo diet (no fruit) before and after Ezetimibe. Now all cholesterol measures are well within normal range."

10 / 10
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30 Report

More FAQ

  • Cindy
  • Taken for less than 1 month
  • May 20, 2019

"My cholesterol is/was at 235 and through a doppler discovered my left interior carotid artery is 100 percent occluded but got somewhat lucky with some strong collateral arteries. My doctor immediately put me on statins...a big no go on all of them, each one I tried (5) I had horrible side effects immediately. Fog like state, shortness of breath, muscle cramps, depression it was terrible. One of my sisters was put on Zetia with no side effects and her cholesterol went from over 300 down to 80. I begged my doctor to let me at least try it and I've just passed the 1 week mark with just a couple of small side effects, tingly legs twice and bloating. So far I love this ezetimibe however the proof will be in 2 months when my cholesterol is rechecked. I am a 65 yr old female."

8 / 10
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30 Report
  • Meena...
  • Taken for 1 to 6 months
  • November 1, 2021

"I have been on statins for the last 4years. Was placed on Crestor last dec and I had serious adverse effects like dizziness, loss of balance by taking just 2 times later placed back on Lipitor 20mg and then since 9 Sept. Lipitor was reduced to 10mg and Ezemitib 10mg was added. Now I have severe joint and muscle pain with mood swings which I can't explain. How often should liver function tests be taken especially when I have cholecystectomy done? What other options are there to reduce high LDL? With no family history of diabetes I now have high levels of HBA1C 6.5-7.2 thanks to statins. Can anyone reading this reply me? I will be very thankful. Take care all Statin users."

1 / 10
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18 Report
  • Barbara
  • Taken for 1 to 6 months
  • August 2, 2021

"Extreme weakness after taking it 2 months. Then extreme hunger but unable to eat much. After stopping for 7 days, all symptoms stopped. PA said it could not be causing my symptoms because they did not appear at first! I stopped any way and after 7 days I am almost OK."

1 / 10
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19 Report
  • GCano
  • August 11, 2020

"I have been taking Ezetimibe, generic for Zetia, for one year with no side effects. With drug RX card I pay $25.00 every 90 days. My collesteral is down to 200 from 238, I still have to little good cholesterol but its better than the pain I get with Statins."

7 / 10
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23 Report
  • Rick
  • Taken for 1 to 6 months
  • July 27, 2019

"I am on Ezetimibe 10 mg together with Simvastatin 20 mg for four weeks. In the mean time I stopped Fenofibrate 134 mg . It seems effective to reduce LDL-Cholesterol by 25%, total-Cholesterol by 30%. Don't know why my Trig level was cut in half from 200 to ~100. So far, don't have much side effect, but will watch in the next 3 months."

6 / 10
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27 Report
  • Dennis...
  • Taken for 6 months to 1 year
  • October 9, 2016

"I was reading this blog with interest. I'm a Canadian . You are being ripped off in the US I am sorry to say. I am on 5mg of Crestor and 10mg of ezetimibe and I do not have insurance. In Canada our social health insurance pays for the doctor but not prescriptions unless you are a senior. The cost of these two drugs together is just under $20.00 per month. Yes, not $200.00 but $20.00 I suggest you vote to put pressure on the drug manufacturers to reduce their pricing structures. And btw, I have tolerated both with no side effects and my Cholesterol numbers for total are very low. My Cardiologist is happy and so am I."

10 / 10
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36 Report
  • Steve
  • Taken for 1 to 6 months
  • March 10, 2021

"Sore shoulders, and neck pain. Taking this with a statin and I stopped the ezetimibe after two months. It has been two weeks off the drug and still sore, although not as bad, read that it can take up to two months for your muscles to heal."

1 / 10
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19 Report
  • Lilypad
  • Taken for 2 to 5 years
  • April 29, 2019

"After having a TIA ( transient ischemic attack ) I was put on avastatin which works well. Now I've been given ezetimibe to go with it and the pain in my legs hurt. Every night I'm tired with headaches all the time. Thinking of dropping it. PS I have swollen ankles too"

4 / 10
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26 Report
  • Michele
  • Taken for 6 months to 1 year
  • December 4, 2018

"I wasn’t sure if I could stay on Zetia at first because my blood pressure was lower than usual (78/56) and I had shortness of breath with extreme fatigue. I secretly took only half a pill and half of my blood pressure medication for a while (not recommended) Almost a month later, everything levelled out and I’m now taking a full dose of both meds with none of the problems listed. I had a lipid panel at the 4 month mark and my values were all normal and my LDL dropped 28 points. Best of all, recent lab work shows my liver enzymes as normal and this was the first medication that didn’t elevate them into the triple digits. I have a bit of back pain along the spine but nothing major. I’m not sure if it’s the Zetia or just me. Unless it gets unbearable, I’m gonna stay the course. $30 for the generic 90 day supply with insurance. Very pleased so far."

10 / 10
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25 Report
  • Wonde...
  • Taken for 1 to 2 years
  • June 5, 2024

Zetia (ezetimibe) "With Crestor, 40mg, my APOB was still in the high 90s. I'm very fit and eat well. Doc added Zetia and my APOB went down to 49. Miraculous. Zetia helps cholesterol “absorbers” as statins help “producers”. There is a blood test by Boston Heart Diagnostics that your doc could order to find out if you are a producer or absorber (or both). If your doctor doesn’t dig this deep before prescribing meds, you need a new doctor."

10 / 10
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1 Report
  • Mik
  • November 3, 2020

"Have been unable to tolerate statins so doc recommended Zetia. The headaches from Zetia are intolerable. I am stopping them. If I don’t I will end up damaging my kidneys by taking too much ibuprofen just to get through the day."

1 / 10
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18 Report
  • Beeth...
  • July 2, 2019

"Has lowered bad cholesterol and raised good cholesterol , but - Not sure if ezetimbe ( 10 m.g. ) or other medications . Feel completely exhausted , can not tolerate statins ( pain ) Changed PCP's ( a Endocrinologist put me on this medicine + Synjardy X-R + amiloride < due to low potassium) also Blood Pressure medications - Lisinopril 20 mg + Amlodopine Besylate 10 mg ? Over medicated ? Have appointment with PCP tomorrow to discuss . Had very recent Metabolic Profile + Hgb A1C = 5.7 so good BP - 127/67 pulse 67 I take BP medication Lisinopril and Amlodopine Besylate at night as too tired if take in day . I take Synjardy and Ezetimbe and Amilirodine in morning , from Endocrinologist last July and great diabetic control med- diet and Home testing NOTE I have Lost > 40 + pounds since August 2018 and dropped from 44 waist to 36-38 I am a male - Yes I adjusted diet but not that radical , Help ? Panic ? Will post > But (IMO ) medication ('s ) cause of fatigue. ?"

7 / 10
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22 Report
  • Ali...
  • Taken for 5 to 10 years
  • October 6, 2023

"I added Zetia, 10mg, to my 40mg daily Crestor, and it drastically improved my HDL (I was routinely around low 40s, and with Zetia, it went to mid 50s). My LDL was also improved (was 120+/-, and with Zetia, it went below 100). I have had no side effects with either of the medications."

9 / 10
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5 Report
  • RJPKe...
  • Taken for less than 1 month
  • October 24, 2017

"Reduced LDL by about 25%, good. But made me feel terrible, disrupted my already tenuous sleep. I tried it 3 times, same result each time. Too bad, as it works to reduce LDL. Need to try something else."

3 / 10
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24 Report
  • LensD...
  • Taken for 1 to 2 years
  • April 4, 2024

"I had elevated LDL but a good level of HDL. I take this medication every other day or just before meals that might be overly fatty. It has brought my LDL down 30 points and my total is now under 200. I have had no side effects."

10 / 10
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2 Report
  • TMano
  • Taken for less than 1 month
  • July 5, 2018

"Starting taking ezetimibe 10mg on 7/1/18. Diarrhea and pain in left side of back by 7/4/18. Taking this along with Simvistatin. Can't continue on the ezetimibe with the back pain especially so will stop until my Dr. & I can figure out another alternative as the Simvistatin 20mg alone not doing it."

1 / 10
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22 Report
  • JonP
  • Taken for 10 years or more
  • November 13, 2021

"Tc was 320. Was on statins and zetia for 10 years til I decided to try whole food, plant-based diet (WFPB). TC dropped to 146, TG:60,APOB:86. Wanted to get APOB down under 70. Worked brilliantly. I’ve NEVER had a reaction to Zetia and am only too happy to be back on it. I consider arterial health as being a prime longevity factor and want to ensure no hardening from any causes."

10 / 10
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11 Report
  • Mycou...
  • January 29, 2021

"After heart attack, I started Vytorin (Zetia & Zocor). My total cholesterol dropped to 120. When components went generic, I took Ezetimibe and Symvastatin. My first Ezetimibe was from Impax labs. I had about 2 weeks of diarrhea in conjunction with the change. I got back on Vytorin for 3 months and diarrhea promptly cleared up. Guessing all generics are not exactly the same, I found different manufacturing for Ezetimibe via Walgreens, and had no problems since. Doctor ran experiment for three months by dropping Ezetimibe, and my total cholesterol went up to 135. I got back on Ezetimibe and my cholesterol went back down. I concluded the combination works well for me. I take it and my other medications during evening soon after dinner with small amount of food. I believe Ezetimibe allows me to control cholesterol with the smallest amount of statin drug - thereby reducing stress on my liver."

10 / 10
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12 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.