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Exenatide for Diabetes, Type 2 User Reviews (Page 4)

Brand names: Bydureon, Byetta, Bydureon BCise

Exenatide has an average rating of 6.4 out of 10 from a total of 367 reviews for the treatment of Diabetes, Type 2. 50% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Exenatide

  • Msty
  • May 18, 2016

Bydureon (exenatide) "I have been taking Bydureon for several years. Prior to Bydureon my A1C was 9.2. It's now 6.4. It took about 6-8 months but the bumps did disappear. The other side effects are now very minimal. I do get bad GI effects if I over eat...but that's a good deterrent. Over three years and still loving it!"

10 / 10
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  • kathy...
  • Taken for 1 to 6 months
  • September 2, 2019

Bydureon BCise (exenatide) "I did a review on 2019-09-02 under the same name (kathyonobx) and this is my update . Bydureon BCise was used for several months. I began to suspect that it had contributed to or caused a deep depression as well as daily migraine headaches which began almost immediately upon use. Update 09-02-2019: My last Bydureon BCise injection was Aug 5, 2019. My first Ozempic .25 mg injection was Aug 12, 2019. I was told it would take 2 weeks for the Bydureon to leave my system. At almost exactly the 2 week mark, my depression stopped and the migraines stopped! I still have an occasional headache, but not migraine strength and not daily."

2 / 10
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  • Anonymous
  • December 27, 2011

Byetta (exenatide) "On 7/19/11 I had a routine A1C and my Doctor called me during the weekend to tell me to drink lots of water and stay away from sugar. My A1C was 11.0 and he was really worried. I started on Metformin 1000 mg a day and then 2000 mg a day. My blood sugar was still consistently in the mid 200's. They started me on Byetta mid-August. After getting used to the nausea, the 5 mcg dose was fine (started 8/4/2011). I switched to the 10 mcg dose one month and once again spent 3-4 weeks dealing with almost crippling nausea that not only made me sick, but worsened my panic problems. I stuck through it though because I could see the changes in my blood sugar. Yesterday 12/26/11 A1C is 5.5 and I have lost 25 lbs. Dr gave me high five!"

9 / 10
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Frequently asked questions

  • magee
  • July 29, 2018

Bydureon BCise (exenatide) "Started taking Bydureon BCise in February 2018, 7 months in and nothing short of miraculous and has changed my life in so many positive ways. A1C at the start was 8.0 after my first blood test it dropped to 5.9 and I've lost approx. 43 lbs. I take Metformin 500 mg twice a day, my fasting sugar varies, from low 80s-115. On two occasions I experienced lows at 70, and 80, it was a new experience for me but a chocolate candy bar and good to go. I like others have read scary reviews about side effects so apprehensive at first but after my 3rd month I noticed nothing bad and began to get comfortable with the injection part, I've found taking the pen out of the refrigerator 30 min prior to injection helps with mixing and comfort when injecting, and it works best if you inject into fatty tissue in your lower abdomen, and alternate weekly. Also it is my courage as I've changed my lifestyle to healthy eating, as the medication will punish you if you make a bad choice trust me on this one !"

10 / 10
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  • 1st m...
  • Taken for 1 to 2 years
  • April 4, 2023

Bydureon BCise (exenatide) "Just had a first malfunction of a BCISE pen. Took the pen out of the fridge, let it sit for 1/2 hour. I then unlocked the pen and shook it to mix the meds. Pressed the pen to my belly area and I heard the click indicating the injector is functioning. The orange indicator never displayed ! I waited a few minutes, then removed the pen and the medicine spewed out of the pen. This is very expensive medicine. One more failure like this and I will move on to an alternative."

9 / 10
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Are you taking this medicine?

  • goodn...
  • May 28, 2008

Byetta (exenatide) "I started taking Byetta 3-4 months ago. It has along with diet, metformin and amaryl, enabled me to stop all insulins, (which I was allergic to). My blood sugar has dropped from the 180-250 range to 84-120, which I am very happy about. I also was informed by my doctor that Byetta reduces fat deposits around the liver so for people who have liver disease it is very important."

8 / 10
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  • 68...
  • Taken for 1 to 6 months
  • November 17, 2015

Bydureon (exenatide) "My wife started a course of Bydureon in the summer. After 3 months she had not only lost weight but her A1C went from 9 6.something. She felt healthier and had no severe reaction. I went on it when I saw how it worked for her. It affects your appetite and you can avoid junk food without and compulsion to eat it. No problems at all except for constipation. I've lost 20+ pounds in three months and have gone down a few inched on the waistline. Very expensive drug with a month's supply being over $1600 but my insurance covered it for both of us."

9 / 10
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More FAQ

  • Anonymous
  • Taken for 1 to 6 months
  • September 25, 2012

Bydureon (exenatide) "I am very happy with Bydureon. I hated the daily injection of Victoza, so this once a week injection is much better. The needle is a little bigger than the pen, but still pretty small when you look at it by itself. I have been taking Bydureon for 3 months and my A1c went from 8.4 to 6.8! Amazing. I also lost 6 lbs."

10 / 10
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  • Seadog
  • April 1, 2015

Bydureon (exenatide) "I'm in my fourth week of taking the med. I'm down 17lbs, my blood sugars have been reduced to where sometimes I have to reduce my night time Lantus or I end up with a low blood sugar event. I love this. I've struggled for years, read about this online, talked with my Dr. and now I'm on my way to getting better."

10 / 10
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  • Melli...
  • June 14, 2016

Bydureon (exenatide) "Bit of nausea at the start but eased off until I changed my stab day then sickness came back for a couple of weeks. 11 weeks in and have dropped 12kg in weight. Blood sugars are way down and have more energy. Struggle to always eat three times a day but when I do I feel great and that's when the weight melts off."

10 / 10
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  • CinCee
  • Taken for 1 to 6 months
  • March 7, 2021

Bydureon BCise (exenatide) "Been using Bcise for 10 weeks, 3 times it has not fully injected so I only got a partial dose. Unlike the old bydureon, you can't move this to find a different spot or change needles to try again. Yes it's easier to work with, but I find it unreliable."

6 / 10
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  • Anonymous
  • October 22, 2010

Byetta (exenatide) "I have been on Byetta for 3 months now. The weight loss is good, 10 lbs and I haven't even exercised. I am on 10 mcg and still have some minimal lingering nausea. My blood sugars are doing great. The biggest side effect for me is that I never feel hungry and this is amazing to me, since before I started taking Byetta, I had a constant feeling of hunger and ate everything in sight. Now, I have to make myself eat. I love Byetta."

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  • Lando...
  • Taken for 1 to 6 months
  • May 2, 2016

Bydureon (exenatide) "I took my sixth Bydureon injection yesterday. The great news is my morning BG levels have dropped dramatically, to the 100 range (after being in the 200s). Bad however, I am debilitatingly nauseous 12 to 24 hours after injecting and 4x have thrown up at the 12 hour mark. I am not a fan of the pea sized lumps at each injection area. The first from 6 weeks ago has not shrunk one iota. The three abdomen injections each itched considerably the first week. I switched to injecting front of my legs, which do not itch. My vision, especially computer monitor distance is horrible, but I think that is due to the drop in my overall blood sugar. I am not sure if I can hang with the nausea and would like more info as to whether it will go away in time."

5 / 10
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  • Hogfa...
  • Taken for 1 to 6 months
  • July 17, 2012

Bydureon (exenatide) "Took over a month for my numbers to begin coming down. Now, after 6 weeks, I'm lower than anything obtained on my previous meds, but still not down to 'normal'. Injections are not a problem. I've been giving my wife B-12 shots for years, so I know to not be timid about sticking the needle in. Does it hurt? Not really. Just a prick that's not any worse than the prick needed for using my meter. Did develop a few nodules that are slow about going away, but they are not sensitive or uncomfortable. No nausea and my appetite is similar to before. Don't like the cost but expect to stay with Bydureon."

9 / 10
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  • Mo 2013
  • Taken for 1 to 6 months
  • May 28, 2013

Bydureon (exenatide) "I was on Bydureon for about 2 months, I really noticed the loss of appetite and lost my sweet tooth. My weight came down and my blood sugar levels dropped from 8.5 to 6.0. I was really happy with the medicine until the known side effects started to show. They were nausea this happened approx once a week in the fourth week in on taking the medicine and bloating, indigestion, a lot of passing wind and acidy burps. Also I felt a bump and itchy feeling around injection area whenever I injected. If they can sort out these side effects then it would be really fantastic for people with Type 2 diabetes. I was really reluctant to stop but the horrible nausea beat me. "

6 / 10
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  • dabrego
  • April 12, 2014

Bydureon (exenatide) "This is an update from my previous posting. I need to correct that I take 1000mg of Metformin NOT 2000mg a day. On Thurday I took my 4th injection of Bydureon. At first I had some nausea and heartburn. By my 3rd injection that has subsided. As far as weight loss, I've only lost 9lbs so far. My fasting sugar in the morning the day after injection is about 118. However, as the week goes on they tend to spike. The highest I've had is 185. Before Bydureon I ranged between 120-150. I've also noticed that my ankles swell by the evening time. Which is somewhat new. During these four weeks I had stopped my Actos because I couldn't afford the copay and but I was able to restart it this week. I put a call into my doctor. I'll see what she has to say"

3 / 10
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  • grate...
  • Taken for 1 to 6 months
  • August 6, 2013

Bydureon (exenatide) "Sugars are running 120. Have to be careful though. I have had them drop as low as 73. Have been on Bydureon for 3 months now. Lost little weight. Appetite is completely gone. Probably wouldn't eat at all, unless I didn't have to take other medicine. Have found that the bumps go away better if you shot in your legs and mix the solution together for about 10 minutes. Still have bumps in stomach from 3 months ago. Hope they will go away over time. Every once in awhile I have a bad reaction at the injection site. Inching and little pain. Usually goes away in 4 days. The price could've been cheaper to start with. Was paying full price. Insurance finally picked up and I'm now paying $74 a month for it. Also taking metformin 2 times a day 500mg each time."

10 / 10
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  • Loren
  • Taken for 1 to 6 months
  • March 20, 2018

Bydureon (exenatide) "Taking Bydureon isn ot worth the risk of Pancreatic cancer, lymphoma, or pancreatitis of which I developed. It almost killed me ; which at this point , it may have been better to be gone. I was admitted to the hospital 1 month ago with acute pancreatitis, renal failure, hepatic and kidney failure. I was on dilaudid IV every 2-3 hours. I developed dissolution of my common bile duct, which Bydureon also causes. Had an ERCP which was a failed attempt because the Bydureon had caused such havoc of the anatomy in my billiary tree and liver. So if that isn't enough I had to have a percutaneous intrahepatic billiary line placement. (drilling into my liver to thread a plastic tube to drain my bile out from the side of me!! ) Yes I walk around with a bag strapped to my leg. My bile cant get through to my intestine !"

1 / 10
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  • mr max
  • Taken for 1 to 6 months
  • January 29, 2013

Bydureon (exenatide) "I am back to update my time on Bydureon. It has been going pretty good. My sugars were really going down I suffered a few lows 40 to 50s so Dr. dropped Januvia and Actos then my sugars started going up. It's been a rough two weeks but hopefully they will level out. My appetite has gone down a lot and looks like I am finally losing some weight."

7 / 10
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  • Anonymous
  • June 22, 2009

Byetta (exenatide) "I have been off and on Byetta for about 2 years. I had issues with vomiting and not being able to tolerate the 10mg. Finally I found the answer. My doctor said to take the injection then wait 1 full hour to eat, and not to eat more than a very very small portion of food. I have not had any upset stomach doing this. I thought it was because of what I ate, like salad dressing or greasy foods, but it was the amount of food that I ate that was making me sick. I haven't been sick this round of using the medicines, using this method and feeling very full after just a few bites of food. Try limiting your food intake to relieve stomach upset."

10 / 10
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  • brn
  • Taken for 2 to 5 years
  • March 20, 2013

Byetta (exenatide) "My a1c is in the normal range now, and I have lost 42 lbs. All my labs are great due to the weight loss. I have been on 10mcg for over 2 years. My last a1c was so good last time, my doctor wants me to decrease to 5mcg. I have been to several dermatologists over the last 2 years trying to figure out why I am having hair loss, unhealthy hair, and change in texture. I never wanted to attribute it to the Byetta although the hair loss started a few months after I began taking it. I am now so desperate to stop the hair loss, I'm considering stopping the Byetta. I can't decide which would be worse - being bald or gaining back 42 pounds! I would really love to know if the person who recently posted had any hair regrowth after stopping Byetta."

10 / 10
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  • mrsgman
  • December 3, 2008

Byetta (exenatide) "I started using byetta in May 07 my A1C was 9.1 now it's 5.2 by blood sugar levels are excellent and as an added bonus. When I started I weighed 340lbs and currently weigh 239lbs. I have watched my diet. It makes you feel full and controls blood sugars. It is awesome I would highly recommend to anyone. 5mg is what I use. 10 mg is too much, it makes me sick. Good luck to you all."

10 / 10
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  • JenCo...
  • Taken for 1 to 6 months
  • April 6, 2016

Bydureon (exenatide) "This drug is HORRIBLE!!! For the entire month I was on it, my blood sugars were never under 200. I was on Trulicity before this, which is a wonderful medication that is the same type as Bydureon, but my insurance said it wouldn't cover the Trulicity for me anymore unless I tried the Bydureon first (?prior authorization). Well...obviously it sucks so thankfully I'll get to go back on the Trulicity, which made my blood sugars extremely steady (around 110) and I was losing weight...like 2 pounds per week. The Bydureon also hurt horribly to inject and always made me bleed, and the mixing it was a pain in the butt. With the Trulicity, it's all done for you and is almost painless, and I never bled at the injection site."

1 / 10
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  • Anonymous
  • April 21, 2012

Byetta (exenatide) "The first week of Byetta 5mcg dose, no side effects, 6 pound weight loss but high blood glucose numbers. My Endocrinologist suggested I try going up to the 10mcg dose. nausea, gas, stomach upset and constipation. I ended up in bed most afternoons. Numbers are now good and I've lost another 4 pounds. Too much lifestyle impairment due to side effects so I went back to the lower dose, still having stomach aches and constipation. I'm giving it time, but so far this has been an uncomfortable experience."

6 / 10
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  • Amand...
  • Taken for 1 to 6 months
  • May 18, 2015

Bydureon (exenatide) "I started 10 weeks ago and saw an immediate drop in my home testing glucose levels, from double figure mmol readings to 4/7mmol after fasting. I had no side effects at all for the first four weeks but subsequently suffered terrible nausea, overnight hypos, skin rash and the most revolting sulphur/egg-smelling burps (cured immediately by Alka Seltzer if anyone else has the same problem!) I've noticed no reduction in appetite (except when nausea has prevented me from eating at all) but had already reduced my intake to 1200 calories a day in an effort to lose weight. If anything, Bydureon is hindering my weight loss. I often see no loss after a week of eating like Snow White, which is disappointing. Overall delighted though."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.