Estradiol topical for Atrophic Urethritis User Reviews

• Lil...
• Taken for 10 years or more
• April 1, 2021

Estradiol topical "I am 80 years old and I've been taking Vagifem for over 15 years since my surgery (Radical hysterectomy for uterine cancer). I trusted my doctor completely and have not had any problems with UTIs or vaginal dryness. I also use a KY-gel product after my shower and have no problem reaching a climax with masturbation, my only sexual release at my age. I also get Vagifem from Canadian Pharmacy for one-third the cost in the States. My younger sister could not tolerate Vagifem for many of the negative reports here, but she also didn't have cancer and is able to get relief from other meds. I really appreciate your comments and wish all the best to my sisters-at-large."

• Lou...
• Taken for 1 to 6 months
• February 9, 2021

Estradiol topical "I am 43 and was skeptical about using Vagifem as I did not have vaginal dryness, which is what it says it’s for. However, I have had problems with ongoing bladder leaking since giving birth to a very large baby and, most recently, consistent UTIs. All I can say is, thank goodness the female doctor I had told me to try this. I have not had any urine leakage at all since I started using Vagifem, which is a miracle, and no bladder infections. There are so many women my age with this issue, it should be prescribed more for this. It’s so good and amazing!"

• Moj...
• Taken for less than 1 month
• February 7, 2020

Estradiol topical "Have been having very painful cystitis and UTIs for over 4 years. I have been given numerous antibiotics over this time. After 1 to 2 weeks of finishing the course, it was back again. I was then kept on antibiotics full time. The specialist then suggested Vagifem. The first one did sting, so I didn't take more. I then tried again 3 weeks later, and the pain and inflammation started to ease. After 4 years of antibiotics that didn't work, I had found a breakthrough med. I cannot believe at the age of 57-62, the GP never thought lack of estrogen could be the cause."

• Bub...
• Taken for 2 to 5 years
• October 15, 2018

Estradiol topical "Changed my life, was out of my mind with pain and cystitis constantly, never thought for one minute would get any improvement, but Vagifem has helped immensely, but if I stop using them I go back to square one, so my gynaecologist said I need them for life, so pray they never stop producing them."

• nur...
• Taken for 2 to 5 years
• August 30, 2020

Estradiol topical "I used Vagifem for years, and the only issue was occasional yeast infections at the beginning, but the drug was effective for vaginal atrophy. Years later, in an HMO that will only prescribe generics, so forced to use Yuvafem. Initially, it seemed okay, but in the last 3 months, I noticed symptoms of burning, itching, and UTI returned. Simultaneously, I just read that Teva, the current generic manufacturer of Yuvafem that I'm using, has been indicted by U.S. Federal prosecutors for drug price-fixing along with other drug manufacturers. While they are only under investigation for price fixing, I hope the FDA is also investigating these companies to determine whether they are interfering with the drug formulation, i.e., cutting with fillers. Caveat emptor - while Vagifem is costly, we may be throwing money down the drain with generics that have filler instead of the drug."

• Ama...
• August 19, 2016

Estradiol topical "After years of suffering with recurrent cystitis, terrible pain in my urethra, bloating, chronic fatigue, I've recently been put on Vagifem and the difference has been incredible. Had previously tried antibiotics, over-the-counter remedies, various herbal treatments - NOTHING worked. I started Vagifem during a bad attack of cystitis and within hours the pain had all but gone. I've also noticed I have more energy, and a little more zest for life! It's early days and I have slight nausea, but so far so good. I'm delighted that something has worked at last."

• Den...
• Taken for 2 to 5 years
• April 3, 2018

Estradiol topical "I have been using Estrace for 5 years - a complete hysterectomy at age 42 - can't live without it - no more nightmares, nerves are calm normally according to my husband - HA! And I don't have hot flashes. I am fortunate that my insurance has always covered it, but in January 2018, a generic came out and my insurance would only pay for the generic. I was fine with that - but two months later I realized the generic was not working. All my symptoms had returned full-blown! My husband told me to go to the pharmacy and pay whatever the name brand Estrace costs! It would have been $325! I told the pharmacist my symptoms on the generic and he called my insurance company - told them I had had a reaction to the generic - they then covered the name brand - within 24 hours I felt like a new person and better each day. I want to say here - the generic did not work for me. Keep working it, women - there IS a way to have a GREAT AND HAPPY LIFE after menopause!"

• dee...
• Taken for less than 1 month
• August 15, 2014

Estradiol topical "For the past 2 years I have suffered terribly with incontinence. A month ago I decided to go to the doctor and she prescribed Vagifem. It was an instantaneous result. I can even jog now without any leaking. It has changed my life. The only negative thing I find is that I gained 2kg or it can be water retention. But not having incontinence outweighs the water retention/weight gain."

• DeD...
• April 23, 2016

Estradiol topical "I have been using Estrace cream for 11 years, and it's been working. I use about 1/3 applicator every 5 or 6 days. Suddenly, it stopped working. I don't have a bladder infection, I already went through yeast infection treatment, both Diflucan and vaginal creams, and my vagina still burns. The Estrace cream relieves it, but only for about 6 or 10 hours. I am 70 and not sexually active. I know years ago the urologist said everything looked kind of shriveled up and dry down there. Could the hormone cream just not work anymore? Now, what do I do?"

• Jil...
• April 8, 2017

Estradiol topical "I have used Estrace samples for 6 months or so. I ran out and went to buy another tube. 375.00! And my insurance didn't cover any of it. (Costco was 325.00) I called my doctor, and they gave me a coupon, but my insurance didn't work with it. So overpriced. And my insurance just went up a 100 dollars a month. I just can't buy a medicine that is so overpriced. I thought it would be 50 dollars or so. There must be something else we can use? Also, the information I read said estrogens may increase the chances of getting cancer of the uterus. Why would we want to take this? I've got to do more homework and find something better!"

• amy...
• October 12, 2019

Estradiol topical "I used this once 3 weeks ago. Immediately had horrible burning and was up all night with what felt like a UTI. Am now on my 3rd antibiotic due to the inflammation and feel like these symptoms will never go away. It may be a Godsend for some, but if you are allergic, it is a nightmare."

• tar...
• February 10, 2016

Estradiol topical "My urologist has just put me on the cream 3 times a week for preventing UTIs. I just started using it, so not sure if it will help with this, but I pray that it does because the past year I have had one UTI after another, and I am tired of being on antibiotics all the time. The antibiotics are so hard on my gut. Anyways, no libido, and hopefully, that will improve too. So far, no bad side effects either, so that's good. I will be 60 in May. I always was very active sexually, now I don't even want to be touched, and my husband is not happy but understanding. So anyways, will report back, and hopefully this cream is a miracle worker!"

• Fed...
• April 27, 2020

Estradiol topical "I started taking Vagifem about 7 weeks ago, on Dr.'s advice, saying it's more effective than tablets. No leaflet in the box to describe side effects. Like you, Brody, I started feeling dizzy one morning when I was getting out of bed. I felt a bump on my nose, and when I opened my eyes, I was on the floor. I fainted and hit my head on the bedside drawer, haven't taken them since."

• lee...
• Taken for 1 to 2 years
• May 10, 2020

Estradiol topical "Used for urethritis (urgency and incontinence) and vaginal dryness. I felt it for the first day or two, but after that, I am not aware it is there. Two weeks before the 90 days are up, I start getting the urgency and getting a little dry and depressed, so I change it before the 90 days are up. It's $100 each ring in Canada, and I get 50% back with insurance. The awful experience of urgency and cost of incontinence products, I would pay double this."

• Hys...
• September 27, 2017

Estradiol topical "Yesterday was the first time I used Estrace Vaginal Cream. I have experienced burning and throbbing. I will not use it again. My co-pay was $146.73. Wish there would have been samples. I could have saved the money."

• Bro...
• December 7, 2016

Estradiol topical "I have been treated successfully for atrophic vaginitis with Vagifem for six years. Unfortunately, because I now have Medicare with supplemental insurance, I have had to get a month's supply of Yuvafem, the new generic for Vagifem, until I can get the brand Vagifem from Canada. The first thing I noticed is how poorly the Yuvafem is packaged. When trying to separate the applicators, the packaging covering the pill area broke open, and I ended up having to cut the applicators apart. Now I wonder if the medication is also a substandard product. Of course, in the U.S., we are unable to tell where our prescription medications are made, whereas in other countries, that information is available."

• Che...
• Taken for less than 1 month
• August 16, 2016

Estradiol topical "I started using Estrace because of frequent urination with burning and dryness. I started menopause 4 yrs ago. When I use Estrace after 2 days, I have to stop due to bleeding and cramping that lasts for a week. I'm not a fan!"

• Ang...
• Taken for less than 1 month
• July 27, 2022

Estradiol topical "47 years old. Prescribed by gynecologist. 1 month of being in a nightmare. Severe vaginal swelling, itchiness, burning, pain, and thrush-like symptoms without discharge but severe pain. My vagina since taking this medication feels like an overripe, rotten, juicy tomato. I also have severe water retention and swelling in my lower body. Just waiting until it's out of my system."

• 123...
• Taken for 1 to 6 months
• May 9, 2017

Estradiol topical "I have used Vagifem for years successfully. Tried Yuvafem... excited about the price drop. After 2 months of use, I am in agony. Dr. confirmed no UTI, but without hormones, it mimics one exactly. Called Dr. and said brand name only for me from now on. Noticed on the box that the first ingredient was corn starch. No wonder it didn't dissolve or work for me. Hope you have better luck."

• New...
• Taken for 1 to 6 months
• March 8, 2018

Estradiol topical "I have not noticed any performance difference between Vagifem vs. Yuvafem. However, the packaging is terrible. I need scissors to separate the applicators from each other; when received, the foil often is ripped, and plungers are often pushed in, thus releasing the drug tablet. Since I have frequent UTIs, I am NOT following advice to manually insert the tablet if it is not in the applicator. My HMO is only looking at the cost factor, and it is very frustrating to be supplied with a very inferior drug product."

• Kat...
• Taken for 6 months to 1 year
• December 25, 2020

Estradiol topical "I'm 61 and was still suffering from night sweats! The nurse recommended Vagifem... and yes, it really helped to ease my night sweats. I can't comment on vaginal atrophy, etc. But if, like me, you still suffer from night sweats, then Vagifem really helped! Thank you."

• IL ...
• Taken for less than 1 month
• September 19, 2022

"My script for estradiol cream caused itching and burning, so my urologist recommended using a compound pharmacy. I received my tiny tube and used a pea-sized amount per instructions. It was prepared in a hypoallergenic base and did not contain a preservative. I had instant extreme burning. Unfortunately, it was expensive, and I'll be throwing it out."

• BLR...
• February 20, 2020

"I had vaginal dryness, painful intercourse, burning, urinary tract infections. My Dr. put me on estradiol cream twice a week, 1 mg. It's been almost 1 month, the burning has stopped, night sweats have improved a lot, but the urethra sometimes bothers me, but not too bad. Overall, it's working okay. My insurance would not pay for Premarin cream but would pay for estradiol cream, so thank goodness for that."

• Jus...
• Taken for less than 1 month
• June 22, 2022

Estradiol topical "I have no idea how it works because I simply can’t insert it. At first, I thought my vaginal area was too dry, so I added a bit of KY jelly, trying to not get any on the ring, which would make it slippery. Even so, I cannot get the ring in no matter how much I compress it. I’m not thrilled with the idea of having to go to my OB/GYN for insertion, but I don’t have a choice. Very frustrated."

• non...
• Taken for 1 to 6 months
• April 19, 2023

Estradiol topical "I gave up on Estring after 90 days. It didn't help with urethra pain, hot flashes returned while using it, and now I am afraid I won't be able to remove it. The cheerful instructional video on how to remove it by Pfizer is not reassuring. I also had to add a Dotti patch in addition to the Estring to combat hot flashes. It was an expensive and unpleasant trial for me."