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Esketamine for Depression User Reviews (Page 3)

Brand names: Spravato

Esketamine has an average rating of 5.6 out of 10 from a total of 64 reviews for the treatment of Depression. 39% of reviewers reported a positive experience, while 38% reported a negative experience.

Reviews for Esketamine

  • Carol
  • Taken for less than 1 month
  • October 5, 2022

Spravato (esketamine) "I was having suicidal ideations when I got my first Spravado last Thursday. The thoughts went away until Saturday morning when I was a mess. I had my second Spravato Monday and have had no ideations back. I am still depressed but it is working for me. I have my third treatment tmrw."

9 / 10
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6 Report
  • Better...
  • Taken for 6 months to 1 year
  • March 7, 2022

Spravato (esketamine) "I’m happy with my results. It took my until the 4th week to feel substantially better. I’m a few months into a weekly maintenance schedule. I found the treatments somewhat unpleasant initially but soon grew used to them. My advice: It’s not a miracle cure, so try to temper your expectations—the limited studies have shown that Spravato + a new antidepressant is maybe 30% more effective than a new antidepressant alone. Although the manufacturer contends people might feel better within days, not everyone will. It’s not a psychedelic therapy; any dissociation is a side effect—talk to your doctor about how Spravato works. The intensity of the dissociation is not an indication of how strong a given treatment is. It’s not a treatment for bipolar, anxiety, or PTSD."

9 / 10
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7 Report
  • sprav...
  • Taken for 1 to 6 months
  • January 11, 2022

Spravato (esketamine) "Started at the Spravato clinic a month ago. The sessions are in a group, which leads to fascinating conversations while under the influence of this drug. Enjoying the comaderie with fellow patients and the inhibition/disassociative effects. Yes, you can get high on this stuff. I haven't experienced any healing yet from my depression...however I've had more stressors than usual this past month, so that benefit may take longer to manifest. Others in my group session have seen great improvement in their mental health. So I suggest to those considering the treatment to at least give it a go!"

7 / 10
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7 Report

Frequently asked questions

  • Spunk...
  • February 4, 2020

"9 treatments. first three weeks, I felt some improvement. laughing, having motivation. Once a week and feel less depressed for 3 days .Then depressed. Treatment feels amazing! Had IV infusions very intense! I couldn't feel my body. Crazy hallucinations nothing scary. Enjoyable. Spravato I feel relaxed like the Pink Floyd's Comfortably Numb! No visual disturbances. Listen to Simon and Garfunkel mellow but upbeat. No rock! I can feel my body, hearing is more sensitive. Music sounds great! Definitely a nasty taste in throat. Candy helps. I stop feeling the effects after 1 hour, drowsy hour 2. Then normal but rest at home. Headphones and playlist, bring a soft blanket, and eye mask. the experience is becoming less pleasurable. Antidepressant effect has been minimal. I wish I more IV was less $. Pure Ketamine is very helpful. For Spravato they've taken away one of the molecules. Research it please"

4 / 10
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10 Report
  • tthyme
  • Taken for less than 1 month
  • April 30, 2023

Spravato (esketamine) "After my second treatment I am feeling more depressed and very tearful and hopeless. I am not sure it’s worth continuing. I have had only very minor side effects so the treatment wasn’t awful. Just not working as quickly as I hoped and actually feeling worse."

5 / 10
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3 Report

Are you taking this medicine?

  • Lones...
  • May 7, 2021

"I've had several Spravato treatments. I must say they have helped me tremendously. All the blah blah blah from researchers who say not enough tests have been done but as I'm sure that while these researchers/MDs treat major depressive disorder, they themselves have not experienced MDD. Spravato has helped me immensely. No SSRI or SNRI has ever really helped. Those drugs, too, have been pushed by big Pharma. I've suffered from depression most of my life. This is the first medication where I have experienced dramatic improvement. Don't know what will happen after I've completed my treatments. But I'm grateful for the relief Spravato has given me."

10 / 10
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3 Report
  • RedEyes
  • Taken for 1 to 6 months
  • March 11, 2023

"It cured my depression. I tried SSRI and tricyclic antidepressants with no benefits. Now I am feeling good thanks to Esketamine. It started to work in one month and I was 100% fine at the end of the second month. Now I m still doing my third month and I have no relapses at all. We are scaling up the drug until it is removed. I'm from Italy here is free thanks to the National Health Service."

10 / 10
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  • Kate
  • Taken for less than 1 month
  • June 16, 2022

"I tried 4 doses of high-dose esketamine. It was absolutely useless! Waste of time! Waste of money! The only effect I experienced was that it tasted bitter when it dripped down my throat. I did not have dissociations, hallucinations, nausea, drowsiness, dizziness or anything else. My vital signs also never changed at all. I simply got angry because I was forced to sit in empty room, bored silly for 2 hours each time. It did nothing for my depression, suicidal ideation or panic attacks. Giving me bad tasting saline would have the same effects as esketamine (and be much cheaper). I think it works purely on a placebo effect! I also haven't responded to numerous antidepressants, CBT or any other treatments either."

1 / 10
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0 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • December 27, 2019

Spravato (esketamine) "Depressed NO MORE.. Thanks Spravato"

10 / 10
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59 Report
  • Bruno
  • Taken for 1 to 6 months
  • January 24, 2020

Spravato (esketamine) "Really Helped. IV is better, but this bridges the gap"

10 / 10
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35 Report
  • 777993
  • October 15, 2019

Spravato (esketamine) "Anybody have increased suicidal thought on spravato?"

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35 Report
  • Santa...
  • Taken for 1 to 6 months
  • June 27, 2019

Spravato (esketamine) "I'm on Spravato and the 56 mg dose is too much. Sick for 4 days after. Then 1 or 2 ok days. Where are all the other reviews? Drs know all that I know. They are no help at all"

2 / 10
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34 Report
  • Still...
  • Taken for 1 to 6 months
  • September 24, 2019

Spravato (esketamine) "Have been on spravato for over a month now and developing headaches. My anxiety level is through the roof. Still sad but not crying. Going in for assessment tomorrow."

1 / 10
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32 Report
  • Jules
  • Taken for less than 1 month
  • August 10, 2021

Spravato (esketamine) "Just had my first treatment. I shouldn’t have been anxious, it was a calm, relaxing experience."

9 / 10
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13 Report
  • Guy...
  • Taken for less than 1 month
  • November 12, 2021

Spravato (esketamine) "Works great, helps with depression and leaves me feeling wonderful."

10 / 10
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12 Report
  • AlboK
  • Taken for 1 to 6 months
  • March 7, 2022

Spravato (esketamine) "8 treatments @28mgs, last two treatments felt terrible during and 3 days after can't sleep and feel sick. Went up to 54mgs sickly past 4 days can't sleep. This is horrible medicine."

1 / 10
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9 Report
  • Still...
  • Taken for 1 to 6 months
  • August 3, 2021

Spravato (esketamine) "Part of a clinical trial for treatment resistant depression without any other antidepressants. I have 2 treatments left and it hasn't worked at all and has made my accompanying anxiety worse!"

2 / 10
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10 Report
  • Depre...
  • January 7, 2023

Spravato (esketamine) "Spravato worked when NOTHING else did. My doctor wanted to Rx another SSRI but I heard about Spravato as adjunctive tx"

10 / 10
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5 Report
  • Capti...
  • Taken for 6 months to 1 year
  • September 13, 2020

"I am now the poster child for this medication esketamine it absolutely saved my life! and it also helped with substance abuse which I've struggled with my entire life."

10 / 10
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10 Report
  • Martha
  • Taken for 1 to 6 months
  • March 9, 2022

Spravato (esketamine) "Horrible side effects. Paranoid, delusional, agitated all the time. Overwhelmed my sense"

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5 Report
  • Linne
  • Taken for less than 1 month
  • January 15, 2023

Spravato (esketamine) "No benefit whatsoever except emptying my wallet by almost $1,000 for 3 treatments over a 2 week period. The nose spray tasted terrible and made me feel 'spaced out'."

1 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.